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The map label for this gene is murG

Identifier: 49475855

GI number: 49475855

Start: 1239619

End: 1240755

Strand: Reverse

Name: murG

Synonym: BH11240

Alternate gene names: 49475855

Gene position: 1240755-1239619 (Counterclockwise)

Preceding gene: 49475856

Following gene: 49475854

Centisome position: 64.25

GC content: 43.1

Gene sequence:

>1137_bases
ATGACTGATAAAAAAGTTATTGTTTTAGCGGCTGGTGGTACAGGTGGGCATCTTTTTCCTGCGGAAGCTGTTGCTGTTGA
ATTAAGGCAGCGTGGATATGATGTTCATTTAGTGACGGATGAAAGGGCACAGCGTTTTGTACGCTGCTTTGATGAAGAGC
ATATACATATCATTTCATCGGCAACATTTACACGACGTCACCCTTTTTCCCTTATAAAAACATTTTGGATGTTGTTAAAA
GGAATGGGACAATCTTTAGCGCTTTTTTATAAACTGTGTCCTGTTCTTGTTGGTGGATTTGGGGGATATCCTACCTTTCC
TCCTCTTATTGTTGCTGCTTTCATGAGGCGTGTAACATTTATTCATGAGCAAAATGCTGTTATGGGGCGTGCCAATCGGG
TATTGGCAGTTTTTGTGTCTGCAATAGCAGGTGGTTTGTTGTCGCAAAATAATCGTTACGCTCATAAAACAGTTTTGACT
GGCAATCCTGTGCGTGATGTTGTTCTCAATGCAGCAGAAATTCCTTATTATCCCTCAGAGGGTGAGAAGCCGTTTCATTT
CTTGATTTTTGGTGGGAGTCAGGGAGCCTCTTTTTTTTCACGAATTGTCCCTGAAGCAATTGCTTTGCTTGATGATAATA
TACGTCAACGTTTACGGATTGTTCAGCAAGTTCGTGGTGATACGGAAGAGTTGATAAAAATCTATCGCCAGATGGATGTG
CAAGCAGAAGTTGCTCCTTTTTTTGATGATATGGCTGAACGTATGGCACGGTCTCAATTTATTTTGTCACGTGCTGGTGC
TTCGTCTGTTTGTGAAATCGCCGTGATTGGTCGACCTGCTCTGCTTATTCCCTATCCTCATGCTTTAGATCACGATCAGG
CAGCGAATGCGGCACTGCTTGCTCGTGTGGGAGGTGCTCAAATTATATCAGAAAAAGATTTGAACGCACAAAGACTTGCT
TCCCTCTTAACAGAAGCCTTTTGTGCACCGCACTTATTGGAAAAACAAGCGCTTGCTGCAAAAAAAGTGGGGCAACCTTA
TGCAACTCGTCGTCTTGCTGATATGGCTGAAGCGTTGATTGTGGGGCGGTCGCTGTCAGATGTAAAGGAGGAGTTTTTTG
ATGAAAATGCCGCTTAA

Upstream 100 bases:

>100_bases
GCGATTGCACTTTCAATGGGCATTTTGCTTAGTTTAACACGCCGCTGGCCAGAAGCGCGTCTTTCAGCTTTTTCCTCTCC
TGTTGTCTTGGATACAATTT

Downstream 100 bases:

>100_bases
TATAGGCCTTATCCATTTTGTCGGAATCGGTGGAATTGGTATGAGTGGAATTGCTGAAGTTTTTCATAATCTTGGTTATA
AAGTTCAAGGATCTGATCAA

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MTDKKVIVLAAGGTGGHLFPAEAVAVELRQRGYDVHLVTDERAQRFVRCFDEEHIHIISSATFTRRHPFSLIKTFWMLLK
GMGQSLALFYKLCPVLVGGFGGYPTFPPLIVAAFMRRVTFIHEQNAVMGRANRVLAVFVSAIAGGLLSQNNRYAHKTVLT
GNPVRDVVLNAAEIPYYPSEGEKPFHFLIFGGSQGASFFSRIVPEAIALLDDNIRQRLRIVQQVRGDTEELIKIYRQMDV
QAEVAPFFDDMAERMARSQFILSRAGASSVCEIAVIGRPALLIPYPHALDHDQAANAALLARVGGAQIISEKDLNAQRLA
SLLTEAFCAPHLLEKQALAAKKVGQPYATRRLADMAEALIVGRSLSDVKEEFFDENAA

Sequences:

>Translated_378_residues
MTDKKVIVLAAGGTGGHLFPAEAVAVELRQRGYDVHLVTDERAQRFVRCFDEEHIHIISSATFTRRHPFSLIKTFWMLLK
GMGQSLALFYKLCPVLVGGFGGYPTFPPLIVAAFMRRVTFIHEQNAVMGRANRVLAVFVSAIAGGLLSQNNRYAHKTVLT
GNPVRDVVLNAAEIPYYPSEGEKPFHFLIFGGSQGASFFSRIVPEAIALLDDNIRQRLRIVQQVRGDTEELIKIYRQMDV
QAEVAPFFDDMAERMARSQFILSRAGASSVCEIAVIGRPALLIPYPHALDHDQAANAALLARVGGAQIISEKDLNAQRLA
SLLTEAFCAPHLLEKQALAAKKVGQPYATRRLADMAEALIVGRSLSDVKEEFFDENAA
>Mature_377_residues
TDKKVIVLAAGGTGGHLFPAEAVAVELRQRGYDVHLVTDERAQRFVRCFDEEHIHIISSATFTRRHPFSLIKTFWMLLKG
MGQSLALFYKLCPVLVGGFGGYPTFPPLIVAAFMRRVTFIHEQNAVMGRANRVLAVFVSAIAGGLLSQNNRYAHKTVLTG
NPVRDVVLNAAEIPYYPSEGEKPFHFLIFGGSQGASFFSRIVPEAIALLDDNIRQRLRIVQQVRGDTEELIKIYRQMDVQ
AEVAPFFDDMAERMARSQFILSRAGASSVCEIAVIGRPALLIPYPHALDHDQAANAALLARVGGAQIISEKDLNAQRLAS
LLTEAFCAPHLLEKQALAAKKVGQPYATRRLADMAEALIVGRSLSDVKEEFFDENAA

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=353, Percent_Identity=31.1614730878187, Blast_Score=127, Evalue=9e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_BARHE (Q6G2Q5)

Other databases:

- EMBL:   BX897699
- RefSeq:   YP_033896.1
- ProteinModelPortal:   Q6G2Q5
- GeneID:   2865367
- GenomeReviews:   BX897699_GR
- KEGG:   bhe:BH11240
- NMPDR:   fig|283166.1.peg.1024
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- ProtClustDB:   PRK00726
- BioCyc:   BHEN283166:BH11240-MONOMER
- BRENDA:   2.4.1.227
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 41692; Mature: 41561

Theoretical pI: Translated: 8.33; Mature: 8.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKKVIVLAAGGTGGHLFPAEAVAVELRQRGYDVHLVTDERAQRFVRCFDEEHIHIISS
CCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEECHHHHHHHHHHHCCCCEEEEEC
ATFTRRHPFSLIKTFWMLLKGMGQSLALFYKLCPVLVGGFGGYPTFPPLIVAAFMRRVTF
CCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
IHEQNAVMGRANRVLAVFVSAIAGGLLSQNNRYAHKTVLTGNPVRDVVLNAAEIPYYPSE
HHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCC
GEKPFHFLIFGGSQGASFFSRIVPEAIALLDDNIRQRLRIVQQVRGDTEELIKIYRQMDV
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
QAEVAPFFDDMAERMARSQFILSRAGASSVCEIAVIGRPALLIPYPHALDHDQAANAALL
CHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEEECCCEEEECCCCCCCCCHHCCHHHH
ARVGGAQIISEKDLNAQRLASLLTEAFCAPHLLEKQALAAKKVGQPYATRRLADMAEALI
HHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
VGRSLSDVKEEFFDENAA
HCCCHHHHHHHHHCCCCC
>Mature Secondary Structure 
TDKKVIVLAAGGTGGHLFPAEAVAVELRQRGYDVHLVTDERAQRFVRCFDEEHIHIISS
CCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEECHHHHHHHHHHHCCCCEEEEEC
ATFTRRHPFSLIKTFWMLLKGMGQSLALFYKLCPVLVGGFGGYPTFPPLIVAAFMRRVTF
CCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
IHEQNAVMGRANRVLAVFVSAIAGGLLSQNNRYAHKTVLTGNPVRDVVLNAAEIPYYPSE
HHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCC
GEKPFHFLIFGGSQGASFFSRIVPEAIALLDDNIRQRLRIVQQVRGDTEELIKIYRQMDV
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
QAEVAPFFDDMAERMARSQFILSRAGASSVCEIAVIGRPALLIPYPHALDHDQAANAALL
CHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEEECCCEEEECCCCCCCCCHHCCHHHH
ARVGGAQIISEKDLNAQRLASLLTEAFCAPHLLEKQALAAKKVGQPYATRRLADMAEALI
HHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
VGRSLSDVKEEFFDENAA
HCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA