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The map label for this gene is cat [H]

Identifier: 49475841

GI number: 49475841

Start: 1219971

End: 1220600

Strand: Reverse

Name: cat [H]

Synonym: BH11080

Alternate gene names: 49475841

Gene position: 1220600-1219971 (Counterclockwise)

Preceding gene: 49475845

Following gene: 49475836

Centisome position: 63.21

GC content: 40.95

Gene sequence:

>630_bases
ATGAATACTAAGAAAGATCTTCGATTCCGTGAGAGTCAGCCTCGTATCAATACAACAGCACGGCTGCATGGTTGTAAATT
GGGGCGCTATGTAGAAATCAACGAGCGGGTGGTTTTACGTGATGTAACGGTTGGAGATTTTTCCTATTTTGAGCATAACA
GTGAAGCTATTTATAGCGATATTGGGCGTTTTTGTTCTATTGCATCTCATGTCTGTGTGAATGCACTAGAACATCCCATG
GAACGCCTTTCAACACATAAAATAACATATCGTCCAAATGAATATTTCCGCTATATGTCCTTAGATCGTTCCTTTCGTGA
AAGGCGTTGTGAAAAGCGTGTTACCGTTGGTCATGATGTATGGATTGGACATGGTGCGGTTATTATGCCTGGGGTGGCAA
TTGGACATGGCGCTATCATTGGTACTAACGCTGTTATAACAAAAGATATTTTACCTTATACGATTGTTGCTGGTGTTCCT
GCAAAACCGTTGCGGATGCGCTTTCCCGATAATGTGATTCAGACACTTTTGGAGATGGCTTGGTGGAATTGGCCACTTGA
TAAAATTTATAATGCGTTGTCTGATATGCAAAACTTACCCATCGAGGTTTTTATTCACAAATGGAAGTAA

Upstream 100 bases:

>100_bases
TGGCAGGTTAGTTTTGCAATCTCATGTTTCATGATTGATTGTGTTTATCAGGTGATTTGTTTTTTCATGTTATTGAGAAA
AAATAATTGGTGAAAGATAA

Downstream 100 bases:

>100_bases
TATTAAAATAAAATGAAAAAATGTTTTTATAATTTAGAAAGGGAGTTTCTGTATGTATATGCTAAGCTTTGCTTACAAAA
TTATCGAGCACTCGTTTTTC

Product: chloramphenicol acetyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MNTKKDLRFRESQPRINTTARLHGCKLGRYVEINERVVLRDVTVGDFSYFEHNSEAIYSDIGRFCSIASHVCVNALEHPM
ERLSTHKITYRPNEYFRYMSLDRSFRERRCEKRVTVGHDVWIGHGAVIMPGVAIGHGAIIGTNAVITKDILPYTIVAGVP
AKPLRMRFPDNVIQTLLEMAWWNWPLDKIYNALSDMQNLPIEVFIHKWK

Sequences:

>Translated_209_residues
MNTKKDLRFRESQPRINTTARLHGCKLGRYVEINERVVLRDVTVGDFSYFEHNSEAIYSDIGRFCSIASHVCVNALEHPM
ERLSTHKITYRPNEYFRYMSLDRSFRERRCEKRVTVGHDVWIGHGAVIMPGVAIGHGAIIGTNAVITKDILPYTIVAGVP
AKPLRMRFPDNVIQTLLEMAWWNWPLDKIYNALSDMQNLPIEVFIHKWK
>Mature_209_residues
MNTKKDLRFRESQPRINTTARLHGCKLGRYVEINERVVLRDVTVGDFSYFEHNSEAIYSDIGRFCSIASHVCVNALEHPM
ERLSTHKITYRPNEYFRYMSLDRSFRERRCEKRVTVGHDVWIGHGAVIMPGVAIGHGAIIGTNAVITKDILPYTIVAGVP
AKPLRMRFPDNVIQTLLEMAWWNWPLDKIYNALSDMQNLPIEVFIHKWK

Specific function: This enzyme is an effector of chloramphenicol resistance in bacteria [H]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.28 [H]

Molecular weight: Translated: 24228; Mature: 24228

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTKKDLRFRESQPRINTTARLHGCKLGRYVEINERVVLRDVTVGDFSYFEHNSEAIYSD
CCCCCCCCCCCCCCCCCCHHEECCCCCCCEEEECCEEEEEEECCCCHHHHHCCCHHHHHH
IGRFCSIASHVCVNALEHPMERLSTHKITYRPNEYFRYMSLDRSFRERRCEKRVTVGHDV
HHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCEE
WIGHGAVIMPGVAIGHGAIIGTNAVITKDILPYTIVAGVPAKPLRMRFPDNVIQTLLEMA
EECCCCEEECCEEECCCEEEECCCEEECCCCCEEEECCCCCCCEEECCCHHHHHHHHHHH
WWNWPLDKIYNALSDMQNLPIEVFIHKWK
HCCCCHHHHHHHHHHHHCCCEEEEEEECC
>Mature Secondary Structure
MNTKKDLRFRESQPRINTTARLHGCKLGRYVEINERVVLRDVTVGDFSYFEHNSEAIYSD
CCCCCCCCCCCCCCCCCCHHEECCCCCCCEEEECCEEEEEEECCCCHHHHHCCCHHHHHH
IGRFCSIASHVCVNALEHPMERLSTHKITYRPNEYFRYMSLDRSFRERRCEKRVTVGHDV
HHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCEE
WIGHGAVIMPGVAIGHGAIIGTNAVITKDILPYTIVAGVPAKPLRMRFPDNVIQTLLEMA
EECCCCEEECCEEECCCEEEECCCEEECCCCCEEEECCCCCCCEEECCCHHHHHHHHHHH
WWNWPLDKIYNALSDMQNLPIEVFIHKWK
HCCCCHHHHHHHHHHHHCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1314803 [H]