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The map label for this gene is coaD [H]

Identifier: 49475755

GI number: 49475755

Start: 1120019

End: 1120552

Strand: Reverse

Name: coaD [H]

Synonym: BH10110

Alternate gene names: 49475755

Gene position: 1120552-1120019 (Counterclockwise)

Preceding gene: 49475756

Following gene: 49475754

Centisome position: 58.03

GC content: 40.82

Gene sequence:

>534_bases
GTGCGGATTGAAATGATGAAAATTGCTCTTTATGCAGGTTCCTTCGATCCTCTTACAAATGGTCATCTTGATATTTTAAA
AGCCAGTTTCGTTTTGGCTGACAAGGTGATTGTGGCTATAGGTATACAGGCTAAAAAAGAATCACTTTTTAGTTTTGAAG
AGCGTGTTGATTTAATTACTCAGGCAGGAAAAGAGTTGTTAAATATGGGGTCTGATCGGTTACAGGTTATTTCGTTTGAG
ACTCTTTTGATTGATAAGGCTCGGGAAATTGGTGCTTCTTTTCTTATTCGCGGATTACGTGATGGCACTGATCTTGATTA
TGAAATGCAAATGGCGGGGATGAATGGTCTCATGGCTCCTGAATTGCAAACTGTTTTTTTGCCGGCAGGCGTTTTGGGGC
GTGTAATAACTTCTACATTGGTACGACAGATTGCCTCTATGGGAGGTGATGTGGCACCTTTTGTGCCTGCGAATGTTGCT
AGAGCTTTGCATTTAAAATTTCAATCTTCAAGGGGGAGTGATTGTGTCTCTTAG

Upstream 100 bases:

>100_bases
AGATGATGATAACCAATTAGATGATGAAACTGAAAAATGTTCCGAGGCGGTTGATGATTCTGAGATGATTGATTTGAGCG
AAGGAAAATAATTTTTAAGA

Downstream 100 bases:

>100_bases
AGTTCTTAGTGTTTTAATATGCTTTTTTTGCTTTTTTTCCTTGAGTGCTGTAGCAGATGATTCTAACGTTCTTGTTTTAT
CTCTCAAAAATGGTGATGTA

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT [H]

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MRIEMMKIALYAGSFDPLTNGHLDILKASFVLADKVIVAIGIQAKKESLFSFEERVDLITQAGKELLNMGSDRLQVISFE
TLLIDKAREIGASFLIRGLRDGTDLDYEMQMAGMNGLMAPELQTVFLPAGVLGRVITSTLVRQIASMGGDVAPFVPANVA
RALHLKFQSSRGSDCVS

Sequences:

>Translated_177_residues
MRIEMMKIALYAGSFDPLTNGHLDILKASFVLADKVIVAIGIQAKKESLFSFEERVDLITQAGKELLNMGSDRLQVISFE
TLLIDKAREIGASFLIRGLRDGTDLDYEMQMAGMNGLMAPELQTVFLPAGVLGRVITSTLVRQIASMGGDVAPFVPANVA
RALHLKFQSSRGSDCVS
>Mature_177_residues
MRIEMMKIALYAGSFDPLTNGHLDILKASFVLADKVIVAIGIQAKKESLFSFEERVDLITQAGKELLNMGSDRLQVISFE
TLLIDKAREIGASFLIRGLRDGTDLDYEMQMAGMNGLMAPELQTVFLPAGVLGRVITSTLVRQIASMGGDVAPFVPANVA
RALHLKFQSSRGSDCVS

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate [H]

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family [H]

Homologues:

Organism=Escherichia coli, GI1790065, Length=159, Percent_Identity=44.0251572327044, Blast_Score=134, Evalue=5e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2 [H]

EC number: =2.7.7.3 [H]

Molecular weight: Translated: 19235; Mature: 19235

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIEMMKIALYAGSFDPLTNGHLDILKASFVLADKVIVAIGIQAKKESLFSFEERVDLIT
CCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHH
QAGKELLNMGSDRLQVISFETLLIDKAREIGASFLIRGLRDGTDLDYEMQMAGMNGLMAP
HHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCC
ELQTVFLPAGVLGRVITSTLVRQIASMGGDVAPFVPANVARALHLKFQSSRGSDCVS
CHHHEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHEEECCCCCCCCCC
>Mature Secondary Structure
MRIEMMKIALYAGSFDPLTNGHLDILKASFVLADKVIVAIGIQAKKESLFSFEERVDLIT
CCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHH
QAGKELLNMGSDRLQVISFETLLIDKAREIGASFLIRGLRDGTDLDYEMQMAGMNGLMAP
HHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCC
ELQTVFLPAGVLGRVITSTLVRQIASMGGDVAPFVPANVARALHLKFQSSRGSDCVS
CHHHEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA