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The map label for this gene is arrD [H]

Identifier: 49475681

GI number: 49475681

Start: 1022616

End: 1023281

Strand: Reverse

Name: arrD [H]

Synonym: BH09240

Alternate gene names: 49475681

Gene position: 1023281-1022616 (Counterclockwise)

Preceding gene: 49475682

Following gene: 49475680

Centisome position: 52.99

GC content: 43.54

Gene sequence:

>666_bases
ATGGCACGAAAAATCAATAAAAATTGTCTCAATTATTTAAAGAAATGGGAAGGGCTACGGCTCCATGCTTATAGAGATGC
TTCTGGTGTTTGGACGATAGGATATGGTCATACAGAAAAAGCGGGTAAGCCGATAGTTGTTGAAGGCATGGTCATTACGG
AAAAAAGAGCGGAAATTCTTCTTTTGGAAGACTTGCGTCAATATGAGCGGGCGGTAGAAAAAGCGGTTTATGTTGACTTA
AGTGACGAGCAGTTTGGTGCTCTTGTTTCCTTTTGTTATAATATAGGGATCATAGCTTTCCAAAATTCTACATTACTTAA
AAAGCTGAATAAAGGCGATTATGAATCTGTACCCATTGAATTGCAGAAATGGACTAGAGCAGGAGGAAAGCGTTTAAAAG
GCTTAGTCCACCGTCGTGCAGCAGAAGCAGGGTTGTGGGCGAAAGGCGCGTTTGTTTCCTCCAACTATCAGACGGTAGAA
AAAAAGCATGCAACAGGGCTTTTCAAAGCCGAAGCCCTTGCACCAGTCATTGGATCTTTCTCAGGTCTTAGTGGTTTTTT
AGCGGGCAATGGTCCCATCCAATGGGCTTTCGCTGCCGTTATGGTTTTTGCTGCCTGTGCTGGCATTTTCTTCGTGGCTA
AGCGTTTTCAGGAGCACTGCCTATGA

Upstream 100 bases:

>100_bases
GCGGTTATTTTCCTGGAAAGGATGCAACGTCTTCCTCCAGTGGCGATGGTGGCGATGGCGCCGTATTAATCAAGGTATAT
TTATAAAATGGAATTGAACG

Downstream 100 bases:

>100_bases
TCTTATGGATGAAAAGAAATCTGCTGTTAACAGGCGCGGCTCTAGCCGCTTTTTTTATAGCCTTAATGAGAGCTTTTCAT
TTTGGCAAGAAGACTGAACA

Product: Phage related lysozyme

Products: NA

Alternate protein names: Endolysin; Lysis protein; Muramidase [H]

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MARKINKNCLNYLKKWEGLRLHAYRDASGVWTIGYGHTEKAGKPIVVEGMVITEKRAEILLLEDLRQYERAVEKAVYVDL
SDEQFGALVSFCYNIGIIAFQNSTLLKKLNKGDYESVPIELQKWTRAGGKRLKGLVHRRAAEAGLWAKGAFVSSNYQTVE
KKHATGLFKAEALAPVIGSFSGLSGFLAGNGPIQWAFAAVMVFAACAGIFFVAKRFQEHCL

Sequences:

>Translated_221_residues
MARKINKNCLNYLKKWEGLRLHAYRDASGVWTIGYGHTEKAGKPIVVEGMVITEKRAEILLLEDLRQYERAVEKAVYVDL
SDEQFGALVSFCYNIGIIAFQNSTLLKKLNKGDYESVPIELQKWTRAGGKRLKGLVHRRAAEAGLWAKGAFVSSNYQTVE
KKHATGLFKAEALAPVIGSFSGLSGFLAGNGPIQWAFAAVMVFAACAGIFFVAKRFQEHCL
>Mature_220_residues
ARKINKNCLNYLKKWEGLRLHAYRDASGVWTIGYGHTEKAGKPIVVEGMVITEKRAEILLLEDLRQYERAVEKAVYVDLS
DEQFGALVSFCYNIGIIAFQNSTLLKKLNKGDYESVPIELQKWTRAGGKRLKGLVHRRAAEAGLWAKGAFVSSNYQTVEK
KHATGLFKAEALAPVIGSFSGLSGFLAGNGPIQWAFAAVMVFAACAGIFFVAKRFQEHCL

Specific function: Essential for lysis of bacterial cell wall, by showing cell wall hydrolyzing activity [H]

COG id: COG3772

COG function: function code R; Phage-related lysozyme (muraminidase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 24 family [H]

Homologues:

Organism=Escherichia coli, GI1786768, Length=126, Percent_Identity=42.0634920634921, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787836, Length=143, Percent_Identity=34.2657342657343, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002196 [H]

Pfam domain/function: PF00959 Phage_lysozyme [H]

EC number: =3.2.1.17 [H]

Molecular weight: Translated: 24506; Mature: 24375

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARKINKNCLNYLKKWEGLRLHAYRDASGVWTIGYGHTEKAGKPIVVEGMVITEKRAEIL
CCCCCCHHHHHHHHHCCCCEEEEEECCCCEEEEECCCCCCCCCCEEEEEEEEECCCHHHH
LLEDLRQYERAVEKAVYVDLSDEQFGALVSFCYNIGIIAFQNSTLLKKLNKGDYESVPIE
HHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHCCEEEECCCHHHHHCCCCCCCCCCHH
LQKWTRAGGKRLKGLVHRRAAEAGLWAKGAFVSSNYQTVEKKHATGLFKAEALAPVIGSF
HHHHHHHHHHHHHHHHHHHHHHCCCEECCCEECCCHHHHHHHHHCCHHHHHHHHHHHHCC
SGLSGFLAGNGPIQWAFAAVMVFAACAGIFFVAKRFQEHCL
CCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ARKINKNCLNYLKKWEGLRLHAYRDASGVWTIGYGHTEKAGKPIVVEGMVITEKRAEIL
CCCCCHHHHHHHHHCCCCEEEEEECCCCEEEEECCCCCCCCCCEEEEEEEEECCCHHHH
LLEDLRQYERAVEKAVYVDLSDEQFGALVSFCYNIGIIAFQNSTLLKKLNKGDYESVPIE
HHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHCCEEEECCCHHHHHCCCCCCCCCCHH
LQKWTRAGGKRLKGLVHRRAAEAGLWAKGAFVSSNYQTVEKKHATGLFKAEALAPVIGSF
HHHHHHHHHHHHHHHHHHHHHHCCCEECCCEECCCHHHHHHHHHCCHHHHHHHHHHHHCC
SGLSGFLAGNGPIQWAFAAVMVFAACAGIFFVAKRFQEHCL
CCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]