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The map label for this gene is nuoG [H]

Identifier: 49475652

GI number: 49475652

Start: 1004050

End: 1006119

Strand: Reverse

Name: nuoG [H]

Synonym: BH08890

Alternate gene names: 49475652

Gene position: 1006119-1004050 (Counterclockwise)

Preceding gene: 49475653

Following gene: 49475651

Centisome position: 52.1

GC content: 40.48

Gene sequence:

>2070_bases
ATGATAAATATCAAAGTTGATGGTAAAGAGATCGAAGTCCCTGATTACTATACGTTGCTTCAAGCTGCTGAGGCGGCGGG
CGCTGAGGTGCCGCGTTTTTGTTTTCATGAATCTTTATCAATTGCTGGAAATTGCCGAATGTGTTTGGTTGAGGTCAAGG
GTGGACCTCCAAAACCTCAAGCTTCCTGTGCTATGGGAGTCCGCGATTTACGCTTAGGACCTAACGGTGAAGCTCCGGAA
ATTTTTACCAATACGGCAATGGTTAAAAAAGCTCGTGAAGGTGTGATGGAGTTTCTTCTCATCAATCACCCTTTAGATTG
TCCTGTGTGTGATCAAGGGGGTGAGTGCGATCTTCAAGATCAAGCAATGCTTTATGGGCGTGACTGTTCTCGTTATACAG
AAAATAAGCGTGCTGTAGAAGATAAATATATTGGGCCACTTGTAAAAACTGTTATGACTCGCTGTATTCATTGCACGCGT
TGTGTTCGTTTTACGACGGAAGTAGCGGGCATTTCAGAGCTTGGTTTAATAGGCCGTGGTGAGGATGCTGAAATTACGAC
ATATCTTGAAAAAGCAATGACATCTGAATTACAGGGAAATGTTATTGATCTTTGTCCAGTGGGAGCTTTAACTTCAAAAC
CTTATGCATTTCATGCCCGTCCATGGGAATTATTTAAAACGGAATCGATTGATGTCATGGATGCACTTGGCAGTGCTATC
CGTATTGATAGCCGGGGTCGTGAGGTTATGCGAATTATGCCGCGTACCAATGAAAATATAAATGAGGAATGGATTTCTGA
TAAGACGCGTTTTATTTGGGATGGACTACGCACTCAGCGGCTTGATAGGCCTTATGTACGCAAAGATGGTAAGCTTCAAC
CTGTAAGTTGGACAGAAGCTTTTGAAAAAATTAAAATGGTGGTTTCTAAAACCTTGCCAGAAAAAATAGGTGCGATTGCA
GGAGATCTTACGTCCATTGAAGAAATGTATGCACTTAAAAAATTACTGATTTCATTGGGATCAAAGATCTTCGATTGTCG
TCAAAGAGGGATGGCTTTGTCTTCTGAGTTAGGCCGTTCGAGTTATATTTTTAATCCAACAATTGCAGGTATTGAACAGG
CTGATGCATTGCTTATCGTAGGGTCTAATCCTCGCTATGAAGCCGCTGTTTTAAATGCACGTATTTTAAAGCGTAAACGA
ATGGGACAATTTCCCATAGCATTAATTGGGGAGAAGGTCGATTTACGTTATCCTTATTCTTATCTTGGAACTGGTACGGA
TGCATTGAATGCACTTATTCGTGGAGAGGATGCGTTTTTTAATGTCTTAAAAGAAGCGAAGAAGCCACTTATTCTTATCG
GGGAGGGAGCTGTTTCAGGTAAAGAGGGCTTGTCTGTTTTAAAAAATCTTGCAAAATTAGCTGATAGTATTGGAGCTCTT
AGTGAAGAATGGAATGGATTTGGGGTTCTTCACAATGCCGCATCGACTGTTGGGGGATTGGACATTGGTTTTACTTCTGA
GCTTGGGGTTGCAAATATTCTTAAAACCTGTGAAGTTTTGTTTTTGCTTGGTGCTGATGAAGTAGAATTAGCTGATATAA
AAGCTTTTACAATTTACATTGGTAGCCACGGTGATAATGGTGCACACTCTGCTGATGTTATTTTACCAGCATCGGCTTAT
ACTGAAAAATCAGGACTTTATGTGAATACAGAAGGACGTGTTCAAATGACAAATCGGGCTGGTTTTGCTCCGGGTGAAGC
AAAAGAAGATTGGGCTATTTTACGGGCTTTATCGGATGTTTTAGGACAAAAGCTTCCTTTTAATTCGCTTTTTCAATTAA
GACAGAGCTTGTTTAATGATTATCCACATCTTTGTGCTATTGATGATATAGTCCCTTCTGATATAGGTGATCTTAAAGCT
CTTGCTTCACAAATGATTGTTTTGGAAACACAAACATTTACTTCCATGGTCAAAGACTTTTATTTGACAAATCCGATAGC
ACGTGCTTCTGCAGTTATGGCTGAATGTTCTTCTCTTGCAAAGAATCGTGCTATGCAAGCTGTAGAGTAA

Upstream 100 bases:

>100_bases
AAAGAAAAAATATTGCTTTAGAAGCAGTAGAATAGAGGGTTTTGCTTTAAGAGCAACAGAATGCAAATTTTAAGTGGGTT
ATCCGCAGGCTGGATGAGTG

Downstream 100 bases:

>100_bases
GGGTAGAGGAAAAGAAATAATGATATATGATTTCTTCATGACCTGGTTATTCCCATTACTTATTATAGTTGGAAAAACGC
TTCTTCTTTTGGTTATTCTC

Product: NADH dehydrogenase subunit G

Products: NA

Alternate protein names: NADH dehydrogenase I, chain 3; NDH-1, chain 3 [H]

Number of amino acids: Translated: 689; Mature: 689

Protein sequence:

>689_residues
MINIKVDGKEIEVPDYYTLLQAAEAAGAEVPRFCFHESLSIAGNCRMCLVEVKGGPPKPQASCAMGVRDLRLGPNGEAPE
IFTNTAMVKKAREGVMEFLLINHPLDCPVCDQGGECDLQDQAMLYGRDCSRYTENKRAVEDKYIGPLVKTVMTRCIHCTR
CVRFTTEVAGISELGLIGRGEDAEITTYLEKAMTSELQGNVIDLCPVGALTSKPYAFHARPWELFKTESIDVMDALGSAI
RIDSRGREVMRIMPRTNENINEEWISDKTRFIWDGLRTQRLDRPYVRKDGKLQPVSWTEAFEKIKMVVSKTLPEKIGAIA
GDLTSIEEMYALKKLLISLGSKIFDCRQRGMALSSELGRSSYIFNPTIAGIEQADALLIVGSNPRYEAAVLNARILKRKR
MGQFPIALIGEKVDLRYPYSYLGTGTDALNALIRGEDAFFNVLKEAKKPLILIGEGAVSGKEGLSVLKNLAKLADSIGAL
SEEWNGFGVLHNAASTVGGLDIGFTSELGVANILKTCEVLFLLGADEVELADIKAFTIYIGSHGDNGAHSADVILPASAY
TEKSGLYVNTEGRVQMTNRAGFAPGEAKEDWAILRALSDVLGQKLPFNSLFQLRQSLFNDYPHLCAIDDIVPSDIGDLKA
LASQMIVLETQTFTSMVKDFYLTNPIARASAVMAECSSLAKNRAMQAVE

Sequences:

>Translated_689_residues
MINIKVDGKEIEVPDYYTLLQAAEAAGAEVPRFCFHESLSIAGNCRMCLVEVKGGPPKPQASCAMGVRDLRLGPNGEAPE
IFTNTAMVKKAREGVMEFLLINHPLDCPVCDQGGECDLQDQAMLYGRDCSRYTENKRAVEDKYIGPLVKTVMTRCIHCTR
CVRFTTEVAGISELGLIGRGEDAEITTYLEKAMTSELQGNVIDLCPVGALTSKPYAFHARPWELFKTESIDVMDALGSAI
RIDSRGREVMRIMPRTNENINEEWISDKTRFIWDGLRTQRLDRPYVRKDGKLQPVSWTEAFEKIKMVVSKTLPEKIGAIA
GDLTSIEEMYALKKLLISLGSKIFDCRQRGMALSSELGRSSYIFNPTIAGIEQADALLIVGSNPRYEAAVLNARILKRKR
MGQFPIALIGEKVDLRYPYSYLGTGTDALNALIRGEDAFFNVLKEAKKPLILIGEGAVSGKEGLSVLKNLAKLADSIGAL
SEEWNGFGVLHNAASTVGGLDIGFTSELGVANILKTCEVLFLLGADEVELADIKAFTIYIGSHGDNGAHSADVILPASAY
TEKSGLYVNTEGRVQMTNRAGFAPGEAKEDWAILRALSDVLGQKLPFNSLFQLRQSLFNDYPHLCAIDDIVPSDIGDLKA
LASQMIVLETQTFTSMVKDFYLTNPIARASAVMAECSSLAKNRAMQAVE
>Mature_689_residues
MINIKVDGKEIEVPDYYTLLQAAEAAGAEVPRFCFHESLSIAGNCRMCLVEVKGGPPKPQASCAMGVRDLRLGPNGEAPE
IFTNTAMVKKAREGVMEFLLINHPLDCPVCDQGGECDLQDQAMLYGRDCSRYTENKRAVEDKYIGPLVKTVMTRCIHCTR
CVRFTTEVAGISELGLIGRGEDAEITTYLEKAMTSELQGNVIDLCPVGALTSKPYAFHARPWELFKTESIDVMDALGSAI
RIDSRGREVMRIMPRTNENINEEWISDKTRFIWDGLRTQRLDRPYVRKDGKLQPVSWTEAFEKIKMVVSKTLPEKIGAIA
GDLTSIEEMYALKKLLISLGSKIFDCRQRGMALSSELGRSSYIFNPTIAGIEQADALLIVGSNPRYEAAVLNARILKRKR
MGQFPIALIGEKVDLRYPYSYLGTGTDALNALIRGEDAFFNVLKEAKKPLILIGEGAVSGKEGLSVLKNLAKLADSIGAL
SEEWNGFGVLHNAASTVGGLDIGFTSELGVANILKTCEVLFLLGADEVELADIKAFTIYIGSHGDNGAHSADVILPASAY
TEKSGLYVNTEGRVQMTNRAGFAPGEAKEDWAILRALSDVLGQKLPFNSLFQLRQSLFNDYPHLCAIDDIVPSDIGDLKA
LASQMIVLETQTFTSMVKDFYLTNPIARASAVMAECSSLAKNRAMQAVE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=709, Percent_Identity=49.3653032440056, Blast_Score=654, Evalue=0.0,
Organism=Escherichia coli, GI145693161, Length=387, Percent_Identity=29.4573643410853, Blast_Score=192, Evalue=9e-50,
Organism=Caenorhabditis elegans, GI17565758, Length=693, Percent_Identity=47.1861471861472, Blast_Score=605, Evalue=1e-173,
Organism=Caenorhabditis elegans, GI32566231, Length=599, Percent_Identity=49.0818030050083, Blast_Score=553, Evalue=1e-158,
Organism=Caenorhabditis elegans, GI193209088, Length=260, Percent_Identity=59.6153846153846, Blast_Score=314, Evalue=9e-86,
Organism=Drosophila melanogaster, GI24640559, Length=702, Percent_Identity=47.8632478632479, Blast_Score=626, Evalue=1e-179,
Organism=Drosophila melanogaster, GI24640557, Length=702, Percent_Identity=47.8632478632479, Blast_Score=626, Evalue=1e-179,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006656
- InterPro:   IPR000283
- InterPro:   IPR010228
- InterPro:   IPR019574
- InterPro:   IPR015405 [H]

Pfam domain/function: PF09326 DUF1982; PF00111 Fer2; PF00384 Molybdopterin; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 75548; Mature: 75548

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS00642 COMPLEX1_75K_2 ; PS00643 COMPLEX1_75K_3 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINIKVDGKEIEVPDYYTLLQAAEAAGAEVPRFCFHESLSIAGNCRMCLVEVKGGPPKPQ
CEEEEECCCEECCCHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCEEEEEEECCCCCCCC
ASCAMGVRDLRLGPNGEAPEIFTNTAMVKKAREGVMEFLLINHPLDCPVCDQGGECDLQD
HHHHHCCHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
QAMLYGRDCSRYTENKRAVEDKYIGPLVKTVMTRCIHCTRCVRFTTEVAGISELGLIGRG
CHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCC
EDAEITTYLEKAMTSELQGNVIDLCPVGALTSKPYAFHARPWELFKTESIDVMDALGSAI
CCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCEECCCCHHHHCCCCCHHHHHCCCCE
RIDSRGREVMRIMPRTNENINEEWISDKTRFIWDGLRTQRLDRPYVRKDGKLQPVSWTEA
EECCCCCHHHHCCCCCCCCCCHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHH
FEKIKMVVSKTLPEKIGAIAGDLTSIEEMYALKKLLISLGSKIFDCRQRGMALSSELGRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCC
SYIFNPTIAGIEQADALLIVGSNPRYEAAVLNARILKRKRMGQFPIALIGEKVDLRYPYS
CEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEECCEEEEECCHH
YLGTGTDALNALIRGEDAFFNVLKEAKKPLILIGEGAVSGKEGLSVLKNLAKLADSIGAL
HHCCCHHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
SEEWNGFGVLHNAASTVGGLDIGFTSELGVANILKTCEVLFLLGADEVELADIKAFTIYI
HHCCCCCEEHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHEEECCCCEEEEEEEEEEEEE
GSHGDNGAHSADVILPASAYTEKSGLYVNTEGRVQMTNRAGFAPGEAKEDWAILRALSDV
ECCCCCCCCCCCEEECCHHCCCCCCEEECCCCCEEECCCCCCCCCCCCHHHHHHHHHHHH
LGQKLPFNSLFQLRQSLFNDYPHLCAIDDIVPSDIGDLKALASQMIVLETQTFTSMVKDF
HCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHEEEHHHHHHHHHHH
YLTNPIARASAVMAECSSLAKNRAMQAVE
HHCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MINIKVDGKEIEVPDYYTLLQAAEAAGAEVPRFCFHESLSIAGNCRMCLVEVKGGPPKPQ
CEEEEECCCEECCCHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCEEEEEEECCCCCCCC
ASCAMGVRDLRLGPNGEAPEIFTNTAMVKKAREGVMEFLLINHPLDCPVCDQGGECDLQD
HHHHHCCHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
QAMLYGRDCSRYTENKRAVEDKYIGPLVKTVMTRCIHCTRCVRFTTEVAGISELGLIGRG
CHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCC
EDAEITTYLEKAMTSELQGNVIDLCPVGALTSKPYAFHARPWELFKTESIDVMDALGSAI
CCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCEECCCCHHHHCCCCCHHHHHCCCCE
RIDSRGREVMRIMPRTNENINEEWISDKTRFIWDGLRTQRLDRPYVRKDGKLQPVSWTEA
EECCCCCHHHHCCCCCCCCCCHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHH
FEKIKMVVSKTLPEKIGAIAGDLTSIEEMYALKKLLISLGSKIFDCRQRGMALSSELGRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCC
SYIFNPTIAGIEQADALLIVGSNPRYEAAVLNARILKRKRMGQFPIALIGEKVDLRYPYS
CEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEECCEEEEECCHH
YLGTGTDALNALIRGEDAFFNVLKEAKKPLILIGEGAVSGKEGLSVLKNLAKLADSIGAL
HHCCCHHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
SEEWNGFGVLHNAASTVGGLDIGFTSELGVANILKTCEVLFLLGADEVELADIKAFTIYI
HHCCCCCEEHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHEEECCCCEEEEEEEEEEEEE
GSHGDNGAHSADVILPASAYTEKSGLYVNTEGRVQMTNRAGFAPGEAKEDWAILRALSDV
ECCCCCCCCCCCEEECCHHCCCCCCEEECCCCCEEECCCCCCCCCCCCHHHHHHHHHHHH
LGQKLPFNSLFQLRQSLFNDYPHLCAIDDIVPSDIGDLKALASQMIVLETQTFTSMVKDF
HCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHEEEHHHHHHHHHHH
YLTNPIARASAVMAECSSLAKNRAMQAVE
HHCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1605643; 8422400 [H]