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The map label for this gene is pgsA [H]

Identifier: 49475348

GI number: 49475348

Start: 650619

End: 651200

Strand: Reverse

Name: pgsA [H]

Synonym: BH05540

Alternate gene names: 49475348

Gene position: 651200-650619 (Counterclockwise)

Preceding gene: 49475349

Following gene: 49475346

Centisome position: 33.72

GC content: 38.49

Gene sequence:

>582_bases
ATGAAAAATCATACTTTTTCTTTTCCAAATATTTTAACTTATGCACGAATTGTTGCTGTGCCAATGGTTGTTGCATGCTT
TTTTTTAGAAGGACGACTGCAATCAAGTGATATTGCACGTTGGGCTGCTGTTTCTATTTTTGTAGTTGCATCTATTACTG
ACTTTCTTGATGGTTACCTTGCCCGTATTTGGGAACAAACATCTAATATTGGGCGCATGTTAGATCCAATTGCAGATAAA
CTTCTCGTCTCGGCCTGTTTACTCTTGCTCGCAGCAGACAGTACTATTGCGGGGTGGACATTATGGGCAGCTATTATTAT
TCTTTGTCGGGAAATTCTTGTATCCGGATTGCGTGAATATTTAGCTGAATTGAAAGTTAGTGTCCCTGTCTCTCGCCTCG
CAAAATGGAAAACTTTTGTACAAATGATAGCTATTATCTTTCTTTTAGCGGGACCAGCTGGCAATAAAATTATCCCTTAT
ACATTGGAATTTGGCATCACTATGCTGTGGATTTCTGCCCTTCTTACATTGTGGACAGGATGGGATTATTTTCGTGCAGG
TTTAAAACATGTTATCATATAA

Upstream 100 bases:

>100_bases
TTTATAACCATTTTAATGAAAAATAGGCTTGTTGCATAATCTTTGCCTTATTACGTTTATAAAGTATATTGTAATTTCAA
AAAAAATTGAAAATAATTTT

Downstream 100 bases:

>100_bases
AAAATGATAAACTTCACAACTCTTTTAAAAAAATTCATAACCTCATAAGAAAAATTCCGAACAGTATGTTTCGGAATTTT
CTGCTTTTCATATATGCCTT

Product: CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MKNHTFSFPNILTYARIVAVPMVVACFFLEGRLQSSDIARWAAVSIFVVASITDFLDGYLARIWEQTSNIGRMLDPIADK
LLVSACLLLLAADSTIAGWTLWAAIIILCREILVSGLREYLAELKVSVPVSRLAKWKTFVQMIAIIFLLAGPAGNKIIPY
TLEFGITMLWISALLTLWTGWDYFRAGLKHVII

Sequences:

>Translated_193_residues
MKNHTFSFPNILTYARIVAVPMVVACFFLEGRLQSSDIARWAAVSIFVVASITDFLDGYLARIWEQTSNIGRMLDPIADK
LLVSACLLLLAADSTIAGWTLWAAIIILCREILVSGLREYLAELKVSVPVSRLAKWKTFVQMIAIIFLLAGPAGNKIIPY
TLEFGITMLWISALLTLWTGWDYFRAGLKHVII
>Mature_193_residues
MKNHTFSFPNILTYARIVAVPMVVACFFLEGRLQSSDIARWAAVSIFVVASITDFLDGYLARIWEQTSNIGRMLDPIADK
LLVSACLLLLAADSTIAGWTLWAAIIILCREILVSGLREYLAELKVSVPVSRLAKWKTFVQMIAIIFLLAGPAGNKIIPY
TLEFGITMLWISALLTLWTGWDYFRAGLKHVII

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=184, Percent_Identity=38.5869565217391, Blast_Score=109, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6320059, Length=165, Percent_Identity=32.7272727272727, Blast_Score=71, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 21566; Mature: 21566

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNHTFSFPNILTYARIVAVPMVVACFFLEGRLQSSDIARWAAVSIFVVASITDFLDGYL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ARIWEQTSNIGRMLDPIADKLLVSACLLLLAADSTIAGWTLWAAIIILCREILVSGLREY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LAELKVSVPVSRLAKWKTFVQMIAIIFLLAGPAGNKIIPYTLEFGITMLWISALLTLWTG
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCC
WDYFRAGLKHVII
HHHHHHHHHHHCC
>Mature Secondary Structure
MKNHTFSFPNILTYARIVAVPMVVACFFLEGRLQSSDIARWAAVSIFVVASITDFLDGYL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ARIWEQTSNIGRMLDPIADKLLVSACLLLLAADSTIAGWTLWAAIIILCREILVSGLREY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LAELKVSVPVSRLAKWKTFVQMIAIIFLLAGPAGNKIIPYTLEFGITMLWISALLTLWTG
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCC
WDYFRAGLKHVII
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA