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The map label for this gene is yheS [H]

Identifier: 49475346

GI number: 49475346

Start: 647705

End: 649582

Strand: Reverse

Name: yheS [H]

Synonym: BH05520

Alternate gene names: 49475346

Gene position: 649582-647705 (Counterclockwise)

Preceding gene: 49475348

Following gene: 49475342

Centisome position: 33.64

GC content: 39.19

Gene sequence:

>1878_bases
ATGTTAGTATTGAATGATATTACAATACGGATAGCTGGGCGTCTTTTAATTAGCCGTGCTAACATTGCTCTTCCTACTGG
TTCAAAAACTGGATTTGTTGGCTATAATGGCACTGGAAAATCAACCCTTTTTCGCGCCATTACAGGTGAAATATCACCCG
AAAACGGCGATATTATTATGCCCAAAAGTACAAAGATTGGTCACGTTGCTCAAGAGGCACCCGCAACCGAACACTCTTTG
CTTGCAACTGTCTTAGCCGCCAACACAGAACACGCCAATCTTCTCCATGAAGCAGAAAGCGCAACTGATCCTCTGCGGAT
TGCTGCCATTTATGCACGCTTAGCCGATATTGATGCCCATGCTGCAGAAGCACGCGCCGGAAAAATCCTCTCTGGTTTAG
GATTTGATTCTCACACACAACAGCGACCTCTCTCATCCTTTTCCGGCGGATGGCGTATGCGAATTGCGCTAGCAGCTATA
CTGTTTACTGAGCCTGATCTTTTACTGCTCGATGAACCAACAAATTATCTCGATATTGAAGGAACTCTCTGGCTCACTGA
GTATGTGCGTCAATACCCCCATACAGTAATCATAATCAGTCATGATCGCGATTTTTTAAATAATACAGTTAATTCTATCA
TGCATCTCGAAAATAACCAACTTACTTTTTGGCGTGGTAATTATGATCAATTTGAACAACAAAAAGCTGAAGTTGTTAAA
GTACAACAAAAACAAATTGAAAAACAAGAAGTGCAACAAAAACATATGGAAGATTTTATTGTTCGTTTTCGTGCTAAAGC
AAGTAAAGCGCGACAAGCGCAATCGCGCCTCAAAGCTCTCGAAAAGCTTAAGCCCCTTACAACGTGGAAAATTCAGCATG
TTCAGCCTTTTATCTTTCCAAAAGTAGAAAAGCCTGTAGCTTCTCCTATTATTGCATTATCAAACGTAAGTGTTGGTTAT
GAAACAGGAAAACCAATTTTAAAAGAATTAAATTTAAGAATTGATAATGATGACCGTATCACTCTCTTGGGCTCAAACGG
AAACGGAAAATCAACTCTTGCTAAATTGCTCGCTGGCCGTCTGAAAGCGGAAAAAGGAACAATCACTCTTGCTCCACATC
TGAAAATTGCTTTTTTTTCTCAACATCAACTTGATGATCTGAAACCGGAAGAAAATGCAATAGATCACATGCGTCATCTC
ATGCCAGGAAAAGCAGACGCTAAAATACGCGCAGCAGTCGCTCGTATGGGAATATCAACGGAAAAAATGATGACAAAAGC
CAAAGAGCTTTCAGGAGGTGAAAAAGTTCGCTTGCTTATGGGACTTACTGTTTTTGAAGGGCCCCATCTTCTTATTCTTG
ATGAACCAACCAATCACCTTGACATTGATAGCCGTCAAGAACTGATACATGCACTCAATCATTTTAATGGAGCAGTAATA
CTTATTGCTCATGACCGCCACCTTATCGAAGCAACAATGGATCGCTTATGGCTTGTGAAAAATAAAACTGTCCTTCCTTA
TGAAGGTGACATGCATACTTACCGTAAAGAGATTCTTGGACTTTCATCCAAAAAAGAAACAAATGTATCCCTCAAAAAAC
AACTTTCCCTTTCTAAAAATGATCAACGAAAAAGCAACGCTCAAAAACGTTCTAGTCTTGCTCCATTACGTAAGAAAATT
GTAGAAACCGAAGCATTGATAGAGTACCTTCATAAACAAATTGCACAACTTGATGAAGAACTTATTTCTGCTTCTTTTCA
TAACAAAATACCTGAAAAAATAAAAGAACGTGCCCAAAAGGCTAAAAAATTACAAGAAGCTGAAACACTCTGGTTTACGT
TATCTGATCAATATGAAACACAAATGATGCAAAAATAA

Upstream 100 bases:

>100_bases
GCCAACTTGCACCAAGAATAAAGATGATAACTACACACTCTCTTTAAAGATTAAATCCACTTGCGCTTATTTTAAAAATA
TGCAAGGGAGATTTTTCATT

Downstream 100 bases:

>100_bases
ACTCTTATCACTTCAAAATTTTGCTTGCTTGGGAACTCTAGGATAATAGCCATCCATAAGGCAAAAAATTCACGACTCGA
CTAAAAATTACGCATCAAAT

Product: ABC transporter, ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 625; Mature: 625

Protein sequence:

>625_residues
MLVLNDITIRIAGRLLISRANIALPTGSKTGFVGYNGTGKSTLFRAITGEISPENGDIIMPKSTKIGHVAQEAPATEHSL
LATVLAANTEHANLLHEAESATDPLRIAAIYARLADIDAHAAEARAGKILSGLGFDSHTQQRPLSSFSGGWRMRIALAAI
LFTEPDLLLLDEPTNYLDIEGTLWLTEYVRQYPHTVIIISHDRDFLNNTVNSIMHLENNQLTFWRGNYDQFEQQKAEVVK
VQQKQIEKQEVQQKHMEDFIVRFRAKASKARQAQSRLKALEKLKPLTTWKIQHVQPFIFPKVEKPVASPIIALSNVSVGY
ETGKPILKELNLRIDNDDRITLLGSNGNGKSTLAKLLAGRLKAEKGTITLAPHLKIAFFSQHQLDDLKPEENAIDHMRHL
MPGKADAKIRAAVARMGISTEKMMTKAKELSGGEKVRLLMGLTVFEGPHLLILDEPTNHLDIDSRQELIHALNHFNGAVI
LIAHDRHLIEATMDRLWLVKNKTVLPYEGDMHTYRKEILGLSSKKETNVSLKKQLSLSKNDQRKSNAQKRSSLAPLRKKI
VETEALIEYLHKQIAQLDEELISASFHNKIPEKIKERAQKAKKLQEAETLWFTLSDQYETQMMQK

Sequences:

>Translated_625_residues
MLVLNDITIRIAGRLLISRANIALPTGSKTGFVGYNGTGKSTLFRAITGEISPENGDIIMPKSTKIGHVAQEAPATEHSL
LATVLAANTEHANLLHEAESATDPLRIAAIYARLADIDAHAAEARAGKILSGLGFDSHTQQRPLSSFSGGWRMRIALAAI
LFTEPDLLLLDEPTNYLDIEGTLWLTEYVRQYPHTVIIISHDRDFLNNTVNSIMHLENNQLTFWRGNYDQFEQQKAEVVK
VQQKQIEKQEVQQKHMEDFIVRFRAKASKARQAQSRLKALEKLKPLTTWKIQHVQPFIFPKVEKPVASPIIALSNVSVGY
ETGKPILKELNLRIDNDDRITLLGSNGNGKSTLAKLLAGRLKAEKGTITLAPHLKIAFFSQHQLDDLKPEENAIDHMRHL
MPGKADAKIRAAVARMGISTEKMMTKAKELSGGEKVRLLMGLTVFEGPHLLILDEPTNHLDIDSRQELIHALNHFNGAVI
LIAHDRHLIEATMDRLWLVKNKTVLPYEGDMHTYRKEILGLSSKKETNVSLKKQLSLSKNDQRKSNAQKRSSLAPLRKKI
VETEALIEYLHKQIAQLDEELISASFHNKIPEKIKERAQKAKKLQEAETLWFTLSDQYETQMMQK
>Mature_625_residues
MLVLNDITIRIAGRLLISRANIALPTGSKTGFVGYNGTGKSTLFRAITGEISPENGDIIMPKSTKIGHVAQEAPATEHSL
LATVLAANTEHANLLHEAESATDPLRIAAIYARLADIDAHAAEARAGKILSGLGFDSHTQQRPLSSFSGGWRMRIALAAI
LFTEPDLLLLDEPTNYLDIEGTLWLTEYVRQYPHTVIIISHDRDFLNNTVNSIMHLENNQLTFWRGNYDQFEQQKAEVVK
VQQKQIEKQEVQQKHMEDFIVRFRAKASKARQAQSRLKALEKLKPLTTWKIQHVQPFIFPKVEKPVASPIIALSNVSVGY
ETGKPILKELNLRIDNDDRITLLGSNGNGKSTLAKLLAGRLKAEKGTITLAPHLKIAFFSQHQLDDLKPEENAIDHMRHL
MPGKADAKIRAAVARMGISTEKMMTKAKELSGGEKVRLLMGLTVFEGPHLLILDEPTNHLDIDSRQELIHALNHFNGAVI
LIAHDRHLIEATMDRLWLVKNKTVLPYEGDMHTYRKEILGLSSKKETNVSLKKQLSLSKNDQRKSNAQKRSSLAPLRKKI
VETEALIEYLHKQIAQLDEELISASFHNKIPEKIKERAQKAKKLQEAETLWFTLSDQYETQMMQK

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=523, Percent_Identity=37.093690248566, Blast_Score=357, Evalue=2e-98,
Organism=Homo sapiens, GI27881506, Length=523, Percent_Identity=35.9464627151052, Blast_Score=336, Evalue=4e-92,
Organism=Homo sapiens, GI10947137, Length=523, Percent_Identity=35.9464627151052, Blast_Score=336, Evalue=5e-92,
Organism=Homo sapiens, GI69354671, Length=546, Percent_Identity=35.3479853479854, Blast_Score=287, Evalue=2e-77,
Organism=Homo sapiens, GI10947135, Length=544, Percent_Identity=34.7426470588235, Blast_Score=287, Evalue=2e-77,
Organism=Homo sapiens, GI31657092, Length=158, Percent_Identity=29.746835443038, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI150417984, Length=207, Percent_Identity=27.536231884058, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1789751, Length=636, Percent_Identity=38.3647798742138, Blast_Score=458, Evalue=1e-130,
Organism=Escherichia coli, GI1787041, Length=524, Percent_Identity=31.4885496183206, Blast_Score=306, Evalue=3e-84,
Organism=Escherichia coli, GI1787182, Length=618, Percent_Identity=28.1553398058252, Blast_Score=239, Evalue=3e-64,
Organism=Escherichia coli, GI2367384, Length=545, Percent_Identity=28.9908256880734, Blast_Score=207, Evalue=2e-54,
Organism=Escherichia coli, GI1788165, Length=197, Percent_Identity=28.9340101522843, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI145693107, Length=453, Percent_Identity=21.8543046357616, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788506, Length=228, Percent_Identity=23.2456140350877, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1787370, Length=213, Percent_Identity=26.2910798122066, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI48994883, Length=213, Percent_Identity=26.2910798122066, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787089, Length=257, Percent_Identity=25.2918287937743, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786398, Length=212, Percent_Identity=25.4716981132075, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI87081782, Length=243, Percent_Identity=28.3950617283951, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1789891, Length=216, Percent_Identity=25, Blast_Score=63, Evalue=6e-11,
Organism=Escherichia coli, GI87081834, Length=183, Percent_Identity=30.0546448087432, Blast_Score=63, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17555318, Length=531, Percent_Identity=36.9114877589454, Blast_Score=356, Evalue=3e-98,
Organism=Caenorhabditis elegans, GI17553372, Length=531, Percent_Identity=37.4764595103578, Blast_Score=352, Evalue=3e-97,
Organism=Caenorhabditis elegans, GI17559834, Length=552, Percent_Identity=33.8768115942029, Blast_Score=314, Evalue=9e-86,
Organism=Caenorhabditis elegans, GI71992285, Length=190, Percent_Identity=28.4210526315789, Blast_Score=73, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6321121, Length=537, Percent_Identity=37.8026070763501, Blast_Score=387, Evalue=1e-108,
Organism=Saccharomyces cerevisiae, GI6320874, Length=530, Percent_Identity=32.4528301886792, Blast_Score=308, Evalue=2e-84,
Organism=Saccharomyces cerevisiae, GI6325030, Length=442, Percent_Identity=28.0542986425339, Blast_Score=151, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6323278, Length=387, Percent_Identity=26.8733850129199, Blast_Score=128, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6324314, Length=386, Percent_Identity=25.6476683937824, Blast_Score=124, Evalue=7e-29,
Organism=Drosophila melanogaster, GI24666836, Length=518, Percent_Identity=39.96138996139, Blast_Score=394, Evalue=1e-110,
Organism=Drosophila melanogaster, GI24642252, Length=525, Percent_Identity=37.1428571428571, Blast_Score=343, Evalue=1e-94,
Organism=Drosophila melanogaster, GI18859989, Length=525, Percent_Identity=37.1428571428571, Blast_Score=343, Evalue=1e-94,
Organism=Drosophila melanogaster, GI24641342, Length=540, Percent_Identity=33.3333333333333, Blast_Score=315, Evalue=5e-86,
Organism=Drosophila melanogaster, GI116007328, Length=242, Percent_Identity=26.8595041322314, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28574150, Length=242, Percent_Identity=26.8595041322314, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281363262, Length=250, Percent_Identity=26, Blast_Score=66, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24653245, Length=250, Percent_Identity=26, Blast_Score=66, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 70301; Mature: 70301

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVLNDITIRIAGRLLISRANIALPTGSKTGFVGYNGTGKSTLFRAITGEISPENGDIIM
CEEEEEEEEEEHHHHHEEECCEEECCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCEEE
PKSTKIGHVAQEAPATEHSLLATVLAANTEHANLLHEAESATDPLRIAAIYARLADIDAH
CCCCCCCCHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCHHH
AAEARAGKILSGLGFDSHTQQRPLSSFSGGWRMRIALAAILFTEPDLLLLDEPTNYLDIE
HHHHHHHHHHHCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHCCCCEEEEECCCCEEECC
GTLWLTEYVRQYPHTVIIISHDRDFLNNTVNSIMHLENNQLTFWRGNYDQFEQQKAEVVK
CEEHHHHHHHHCCCEEEEEECCHHHHHHHHHHHEEECCCEEEEEECCHHHHHHHHHHHHH
VQQKQIEKQEVQQKHMEDFIVRFRAKASKARQAQSRLKALEKLKPLTTWKIQHVQPFIFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCC
KVEKPVASPIIALSNVSVGYETGKPILKELNLRIDNDDRITLLGSNGNGKSTLAKLLAGR
CCCCCHHCCEEEEECCCCCCCCCCHHHHHCCCEECCCCEEEEEECCCCCHHHHHHHHHHH
LKAEKGTITLAPHLKIAFFSQHQLDDLKPEENAIDHMRHLMPGKADAKIRAAVARMGIST
HCCCCCEEEEECCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCH
EKMMTKAKELSGGEKVRLLMGLTVFEGPHLLILDEPTNHLDIDSRQELIHALNHFNGAVI
HHHHHHHHHCCCCCEEEEEEEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCEEE
LIAHDRHLIEATMDRLWLVKNKTVLPYEGDMHTYRKEILGLSSKKETNVSLKKQLSLSKN
EEECCCHHHHHHHHHEEEEECCEECCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHCCCCC
DQRKSNAQKRSSLAPLRKKIVETEALIEYLHKQIAQLDEELISASFHNKIPEKIKERAQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
AKKLQEAETLWFTLSDQYETQMMQK
HHHHHHHHEEEEEECCHHHHHHHCC
>Mature Secondary Structure
MLVLNDITIRIAGRLLISRANIALPTGSKTGFVGYNGTGKSTLFRAITGEISPENGDIIM
CEEEEEEEEEEHHHHHEEECCEEECCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCEEE
PKSTKIGHVAQEAPATEHSLLATVLAANTEHANLLHEAESATDPLRIAAIYARLADIDAH
CCCCCCCCHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCHHH
AAEARAGKILSGLGFDSHTQQRPLSSFSGGWRMRIALAAILFTEPDLLLLDEPTNYLDIE
HHHHHHHHHHHCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHCCCCEEEEECCCCEEECC
GTLWLTEYVRQYPHTVIIISHDRDFLNNTVNSIMHLENNQLTFWRGNYDQFEQQKAEVVK
CEEHHHHHHHHCCCEEEEEECCHHHHHHHHHHHEEECCCEEEEEECCHHHHHHHHHHHHH
VQQKQIEKQEVQQKHMEDFIVRFRAKASKARQAQSRLKALEKLKPLTTWKIQHVQPFIFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCC
KVEKPVASPIIALSNVSVGYETGKPILKELNLRIDNDDRITLLGSNGNGKSTLAKLLAGR
CCCCCHHCCEEEEECCCCCCCCCCHHHHHCCCEECCCCEEEEEECCCCCHHHHHHHHHHH
LKAEKGTITLAPHLKIAFFSQHQLDDLKPEENAIDHMRHLMPGKADAKIRAAVARMGIST
HCCCCCEEEEECCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCH
EKMMTKAKELSGGEKVRLLMGLTVFEGPHLLILDEPTNHLDIDSRQELIHALNHFNGAVI
HHHHHHHHHCCCCCEEEEEEEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCEEE
LIAHDRHLIEATMDRLWLVKNKTVLPYEGDMHTYRKEILGLSSKKETNVSLKKQLSLSKN
EEECCCHHHHHHHHHEEEEECCEECCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHCCCCC
DQRKSNAQKRSSLAPLRKKIVETEALIEYLHKQIAQLDEELISASFHNKIPEKIKERAQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
AKKLQEAETLWFTLSDQYETQMMQK
HHHHHHHHEEEEEECCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]