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The map label for this gene is hutC [H]

Identifier: 49475289

GI number: 49475289

Start: 577252

End: 578349

Strand: Reverse

Name: hutC [H]

Synonym: BH04940

Alternate gene names: 49475289

Gene position: 578349-577252 (Counterclockwise)

Preceding gene: 49475290

Following gene: 49475288

Centisome position: 29.95

GC content: 40.98

Gene sequence:

>1098_bases
ATGCTAGACACTCCATCCATTGTGCATACATCTGAAACAAAGGAGAATAAAAGAGTAAGTCGTGCGAACTTAGCAAAAAT
TTTGCTCTTAAGTTTAATTGTGTTTCTTATCTTCAGCATTTTTGGAGGACTCTTGCATGGTGCATCAAAGGCTTCTTTCA
TTGATTTCCTTCATGTAATGCTCACACAAGATTTTTCGATGAGTAGTAGAACGCGTGATTACCTCATACTTATAGACATA
AGACTGCCGCGTATTATCTTGGGAGTGTTAGTTGGAGCAGCTCTTGCTGTCTCTGGTGTTCTTATGCAAGGTCTTTTCCG
TAACCCTCTTGCAGATCCGGGGATTGTAGGCGTATCTGCAGGTGCCGGTCTTGGAGCTGTTTTAGCAATTGTTGTCGGTA
TTGCCTTTCCTTCTTCATTGGCACCTTTTCTAGAACCTTACAAGGTTATCATAGGTGCATTTTGTGGTGGTCTATTATCA
ACAATTGTTCTCTACGCGATAGCAACACGTCATAGTTGCACATCTATTGCAACAATGCTTCTTGCAGGCATTGCTCTTGG
TGCCTTAAGCAGTGCTGTTGTTGGAACATTAATTTTTATCGCAAATGACCAACAATTACGTGATATTACTTTTTGGAATC
TTGGCTCTCTTGCAGGTGCAACATGGTTGAAAGTGTGGCTTGTTTTTCCCTTTATCTGTATTGGTCTTCTTTTTTCTCCT
TTTTTATCACGCGCCCTTAATGCTCTTGCTCTTGGAGAAGCTGTTGCTGGCCACATTGGCTTCCATATTCAACGGATTAA
AAATATTGCTATTTTCCTTGTTGCACTTATGTGTGGTAGCGCAGTCGCTATCAGTGGCGGTATTGGTTTTATCGGTATTG
TTGTTCCCCATATTTTGCGTCAACTCATTGGTCCTGATCATCGCTATCTTATTCCTTGCTCAGCCCTCTTAGGAGCGGCA
TTACTTATTTTTGCCGATACCTTTGCACGCTTAATTGTAGCCCCAGCAGAATTACCAATCGGAATTGTTACAGCACTTTT
TGGTGCACCTTTTTTCCTTTGGATTCTTATATGCAAACGAGGAATAAATTTTTCATGA

Upstream 100 bases:

>100_bases
GCTATGTATCTTTTAGGATTTGGTCCACGTACTGCAAACGCATCAAAGGAGCTTATTGATATGCTCTATGGTGTAGGTCA
AAATGGTAAGAGCTTATAAC

Downstream 100 bases:

>100_bases
TTGAAGCAGTTGATATCTGCGTTCAACGCGGAAAAAAACAGATCCTCAAACATGTTGACCTCCAAGCAAAAAATGGTGCT
ATAACCGTCATTATCGGTCC

Product: hemin ABC transporter, permease protein

Products: ADP; phosphate; cob(I)alamin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MLDTPSIVHTSETKENKRVSRANLAKILLLSLIVFLIFSIFGGLLHGASKASFIDFLHVMLTQDFSMSSRTRDYLILIDI
RLPRIILGVLVGAALAVSGVLMQGLFRNPLADPGIVGVSAGAGLGAVLAIVVGIAFPSSLAPFLEPYKVIIGAFCGGLLS
TIVLYAIATRHSCTSIATMLLAGIALGALSSAVVGTLIFIANDQQLRDITFWNLGSLAGATWLKVWLVFPFICIGLLFSP
FLSRALNALALGEAVAGHIGFHIQRIKNIAIFLVALMCGSAVAISGGIGFIGIVVPHILRQLIGPDHRYLIPCSALLGAA
LLIFADTFARLIVAPAELPIGIVTALFGAPFFLWILICKRGINFS

Sequences:

>Translated_365_residues
MLDTPSIVHTSETKENKRVSRANLAKILLLSLIVFLIFSIFGGLLHGASKASFIDFLHVMLTQDFSMSSRTRDYLILIDI
RLPRIILGVLVGAALAVSGVLMQGLFRNPLADPGIVGVSAGAGLGAVLAIVVGIAFPSSLAPFLEPYKVIIGAFCGGLLS
TIVLYAIATRHSCTSIATMLLAGIALGALSSAVVGTLIFIANDQQLRDITFWNLGSLAGATWLKVWLVFPFICIGLLFSP
FLSRALNALALGEAVAGHIGFHIQRIKNIAIFLVALMCGSAVAISGGIGFIGIVVPHILRQLIGPDHRYLIPCSALLGAA
LLIFADTFARLIVAPAELPIGIVTALFGAPFFLWILICKRGINFS
>Mature_365_residues
MLDTPSIVHTSETKENKRVSRANLAKILLLSLIVFLIFSIFGGLLHGASKASFIDFLHVMLTQDFSMSSRTRDYLILIDI
RLPRIILGVLVGAALAVSGVLMQGLFRNPLADPGIVGVSAGAGLGAVLAIVVGIAFPSSLAPFLEPYKVIIGAFCGGLLS
TIVLYAIATRHSCTSIATMLLAGIALGALSSAVVGTLIFIANDQQLRDITFWNLGSLAGATWLKVWLVFPFICIGLLFSP
FLSRALNALALGEAVAGHIGFHIQRIKNIAIFLVALMCGSAVAISGGIGFIGIVVPHILRQLIGPDHRYLIPCSALLGAA
LLIFADTFARLIVAPAELPIGIVTALFGAPFFLWILICKRGINFS

Specific function: Part of the binding-protein-dependent transport system for hemin; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788004, Length=286, Percent_Identity=43.7062937062937, Blast_Score=181, Evalue=7e-47,
Organism=Escherichia coli, GI1790740, Length=289, Percent_Identity=40.1384083044983, Blast_Score=178, Evalue=6e-46,
Organism=Escherichia coli, GI1786805, Length=300, Percent_Identity=37.3333333333333, Blast_Score=141, Evalue=5e-35,
Organism=Escherichia coli, GI1790741, Length=286, Percent_Identity=34.965034965035, Blast_Score=141, Evalue=6e-35,
Organism=Escherichia coli, GI1786804, Length=285, Percent_Identity=30.8771929824561, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1786347, Length=285, Percent_Identity=31.2280701754386, Blast_Score=102, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 38641; Mature: 38641

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDTPSIVHTSETKENKRVSRANLAKILLLSLIVFLIFSIFGGLLHGASKASFIDFLHVM
CCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LTQDFSMSSRTRDYLILIDIRLPRIILGVLVGAALAVSGVLMQGLFRNPLADPGIVGVSA
HHCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECC
GAGLGAVLAIVVGIAFPSSLAPFLEPYKVIIGAFCGGLLSTIVLYAIATRHSCTSIATML
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAGIALGALSSAVVGTLIFIANDQQLRDITFWNLGSLAGATWLKVWLVFPFICIGLLFSP
HHHHHHHHHHHHHHHHHHHEECCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FLSRALNALALGEAVAGHIGFHIQRIKNIAIFLVALMCGSAVAISGGIGFIGIVVPHILR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCCHHHHHHHHHHHHH
QLIGPDHRYLIPCSALLGAALLIFADTFARLIVAPAELPIGIVTALFGAPFFLWILICKR
HHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHC
GINFS
CCCCC
>Mature Secondary Structure
MLDTPSIVHTSETKENKRVSRANLAKILLLSLIVFLIFSIFGGLLHGASKASFIDFLHVM
CCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LTQDFSMSSRTRDYLILIDIRLPRIILGVLVGAALAVSGVLMQGLFRNPLADPGIVGVSA
HHCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECC
GAGLGAVLAIVVGIAFPSSLAPFLEPYKVIIGAFCGGLLSTIVLYAIATRHSCTSIATML
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAGIALGALSSAVVGTLIFIANDQQLRDITFWNLGSLAGATWLKVWLVFPFICIGLLFSP
HHHHHHHHHHHHHHHHHHHEECCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FLSRALNALALGEAVAGHIGFHIQRIKNIAIFLVALMCGSAVAISGGIGFIGIVVPHILR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCCHHHHHHHHHHHHH
QLIGPDHRYLIPCSALLGAALLIFADTFARLIVAPAELPIGIVTALFGAPFFLWILICKR
HHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHC
GINFS
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; cob(I)alamin [Periplasm]; H2O [C]

Specific reaction: ATP + cob(I)alamin [Periplasm] + H2O = ADP + phosphate + cob(I)alamin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9026634; 11586360; 12142430 [H]