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The map label for this gene is thiO [H]

Identifier: 49475285

GI number: 49475285

Start: 568361

End: 569311

Strand: Reverse

Name: thiO [H]

Synonym: BH04900

Alternate gene names: 49475285

Gene position: 569311-568361 (Counterclockwise)

Preceding gene: 49475286

Following gene: 49475284

Centisome position: 29.48

GC content: 39.85

Gene sequence:

>951_bases
TTGAAAAACATTCTTATTAAAGGTGCAGGTGTAGGGGGATTAACAGTCGCCTTTATGTTACAACAAAAAGGTGTTTCTGT
TACCATTTCAGCACCCCCTCATTCTCCTGTAGGAACTGCTAGTTGGTATGCAGGAGGAATGCTAGCACCTTACTGTGAAA
AAGAAAACGCTGAACAAATCGTTGAAGACCTTGGCATACAAGCGATACAATGGTGGCATAAAACACTTCCCAATCTCGTC
ATACGAAAAGGAACTTTAGTTGTTGCACCTACACGGGATAGGGGAGAACTTGAACGATTTTCAGCGCGTACACATCATCA
TAAAATTATAAATGGTGAGGAAATAGCACATCTTGAACCGGATCTTGCAGAACGTTTCAACCACGCACTCTTTTATGAAA
ATGAAGCACATCTTGACCCGCGCCAAGCACTTATCACTTTAAAAGAAGATCTTATAAAAAATGGAGTCTGTTTTGTTGAT
ATAGAAACATCTGAAAAAAAATTTGATCTTGTCATTGATGCGACTGGAATAGCGCGTTTAGGAAAAGACAAAAATATACG
GGGTGTACGCGGCGAAATGCTTCTCGTACGCAGCACAGATATTAAAATTTCTCGTCCAATTCGCCTCCTTCATCCACGAT
TTCCTCTCTATATTGTTCCTCGGCAAGATAATATTTTTATGATTGGCGCAACAATGATTGAAAGTGACTTTGATGGTGCC
ATCTCGATAAGATCAATGATGGAATTACTCAATGCGGCTTATACCTTGCATCCTGCTTTTGCCGAAGCAGAAATTATTGA
ATCCGGCGTTGGTATACGACCATCTTATCCTGATAACTTCCCTTCTGTATACAAATATGGTAACCATATTTCTATTAACG
GATTTTATAGACATGGTTTCCTTTTATCTCCCGAAATGGCAACACGAGCGATGAAATTGGCGTTGGAGTAA

Upstream 100 bases:

>100_bases
AAATAAAAGATGAAGGTATGGTCGCCATGGCGGAAAAATATCAAAAGAATGGTGATCTCTATATAGACGTTAGTCCTCCT
CAAAAGAAGATAGTAAACCA

Downstream 100 bases:

>100_bases
AGCATGCAAATATTTGTCAATGGTGAAACAATCGAAACAGAAGTCATCACTCTCAATCTGTTGCTTGAAGAATTAGGTTA
TGAAGGAAATTGGCTCGCAA

Product: thiamine biosynthesis oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MKNILIKGAGVGGLTVAFMLQQKGVSVTISAPPHSPVGTASWYAGGMLAPYCEKENAEQIVEDLGIQAIQWWHKTLPNLV
IRKGTLVVAPTRDRGELERFSARTHHHKIINGEEIAHLEPDLAERFNHALFYENEAHLDPRQALITLKEDLIKNGVCFVD
IETSEKKFDLVIDATGIARLGKDKNIRGVRGEMLLVRSTDIKISRPIRLLHPRFPLYIVPRQDNIFMIGATMIESDFDGA
ISIRSMMELLNAAYTLHPAFAEAEIIESGVGIRPSYPDNFPSVYKYGNHISINGFYRHGFLLSPEMATRAMKLALE

Sequences:

>Translated_316_residues
MKNILIKGAGVGGLTVAFMLQQKGVSVTISAPPHSPVGTASWYAGGMLAPYCEKENAEQIVEDLGIQAIQWWHKTLPNLV
IRKGTLVVAPTRDRGELERFSARTHHHKIINGEEIAHLEPDLAERFNHALFYENEAHLDPRQALITLKEDLIKNGVCFVD
IETSEKKFDLVIDATGIARLGKDKNIRGVRGEMLLVRSTDIKISRPIRLLHPRFPLYIVPRQDNIFMIGATMIESDFDGA
ISIRSMMELLNAAYTLHPAFAEAEIIESGVGIRPSYPDNFPSVYKYGNHISINGFYRHGFLLSPEMATRAMKLALE
>Mature_316_residues
MKNILIKGAGVGGLTVAFMLQQKGVSVTISAPPHSPVGTASWYAGGMLAPYCEKENAEQIVEDLGIQAIQWWHKTLPNLV
IRKGTLVVAPTRDRGELERFSARTHHHKIINGEEIAHLEPDLAERFNHALFYENEAHLDPRQALITLKEDLIKNGVCFVD
IETSEKKFDLVIDATGIARLGKDKNIRGVRGEMLLVRSTDIKISRPIRLLHPRFPLYIVPRQDNIFMIGATMIESDFDGA
ISIRSMMELLNAAYTLHPAFAEAEIIESGVGIRPSYPDNFPSVYKYGNHISINGFYRHGFLLSPEMATRAMKLALE

Specific function: May have amino acid oxidase activity in the biosynthesis of thiazole when cysteine gives its thiol group to be inserted into the thiazole molecule and the rest of the molecule is deaminated to give pyruvic acid and ammonia [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR012727 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: NA

Molecular weight: Translated: 35325; Mature: 35325

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNILIKGAGVGGLTVAFMLQQKGVSVTISAPPHSPVGTASWYAGGMLAPYCEKENAEQI
CCCEEEEECCCCHHHHEEEEHHCCCEEEEECCCCCCCCCCCHHCCCEECCCCCCCCHHHH
VEDLGIQAIQWWHKTLPNLVIRKGTLVVAPTRDRGELERFSARTHHHKIINGEEIAHLEP
HHHHCHHHHHHHHHHCCHHEEECCEEEEEECCCCHHHHHHHHHHHHCEECCCCCEEECCC
DLAERFNHALFYENEAHLDPRQALITLKEDLIKNGVCFVDIETSEKKFDLVIDATGIARL
HHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHCCEEEEEEECCCCEEEEEEECCCHHHC
GKDKNIRGVRGEMLLVRSTDIKISRPIRLLHPRFPLYIVPRQDNIFMIGATMIESDFDGA
CCCCCCCCCCCCEEEEEECCEEEECCEEEECCCCCEEEEECCCCEEEEEEEEECCCCCCH
ISIRSMMELLNAAYTLHPAFAEAEIIESGVGIRPSYPDNFPSVYKYGNHISINGFYRHGF
HHHHHHHHHHHHHEEECCCHHHHHHHHCCCCCCCCCCCCCCHHHHCCCEEEEEEEEECCE
LLSPEMATRAMKLALE
EECHHHHHHHHHHCCC
>Mature Secondary Structure
MKNILIKGAGVGGLTVAFMLQQKGVSVTISAPPHSPVGTASWYAGGMLAPYCEKENAEQI
CCCEEEEECCCCHHHHEEEEHHCCCEEEEECCCCCCCCCCCHHCCCEECCCCCCCCHHHH
VEDLGIQAIQWWHKTLPNLVIRKGTLVVAPTRDRGELERFSARTHHHKIINGEEIAHLEP
HHHHCHHHHHHHHHHCCHHEEECCEEEEEECCCCHHHHHHHHHHHHCEECCCCCEEECCC
DLAERFNHALFYENEAHLDPRQALITLKEDLIKNGVCFVDIETSEKKFDLVIDATGIARL
HHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHCCEEEEEEECCCCEEEEEEECCCHHHC
GKDKNIRGVRGEMLLVRSTDIKISRPIRLLHPRFPLYIVPRQDNIFMIGATMIESDFDGA
CCCCCCCCCCCCEEEEEECCEEEECCEEEECCCCCEEEEECCCCEEEEEEEEECCCCCCH
ISIRSMMELLNAAYTLHPAFAEAEIIESGVGIRPSYPDNFPSVYKYGNHISINGFYRHGF
HHHHHHHHHHHHHEEECCCHHHHHHHHCCCCCCCCCCCCCCHHHHCCCEEEEEEEEECCE
LLSPEMATRAMKLALE
EECHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371431 [H]