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The map label for this gene is comM [H]

Identifier: 49474869

GI number: 49474869

Start: 59552

End: 61084

Strand: Reverse

Name: comM [H]

Synonym: BH00440

Alternate gene names: 49474869

Gene position: 61084-59552 (Counterclockwise)

Preceding gene: 49474872

Following gene: 49474867

Centisome position: 3.16

GC content: 44.88

Gene sequence:

>1533_bases
ATGATCGCGTGTGTTACAACGGTTGCTTTTCGTGGTCTAGAAGCAGTACCTGTTGATGTACAGGTTATGATTTCCTCTGG
TAAAATAGGCATGGCTATTGTTGGATTGCCAGATAAAGCAATCGCAGAAAGTCGTGAACGTGTTCAAGCAGCCTTTCATG
CTTGCGGACTTTCTATGCCCAATAAACGGGTCACTATTAATCTTGCGCCTGCTGATCTCCCTAAAGAGGGATCACATTAT
GATTTGCCAATCGCCGTAGGCTTAATGCTCGCTATGGGACTTCTTCCTCCTGACGTAGAACAAGACTACATCATTTTAGG
CGAATTATCACTGGATGGTTCACTTACAGCAGTTAATGGTGTTTTACCAGCAGCGATGACAGCTTTATCATGCGATAAAG
GACTTATTTGTCCCTATCAATGTGGACCTGAAGCGGCATGGGCAAATGCAGAAATGAATATTCTCGCACCCGAAACGCTT
CTTACCATGGTCAATCATTTTAAAGGAACACAAATTCAAAAACGTCCACAACCACGCCAATATACCATCCAAAATGAGCT
TCCAGATCTTTGCGAAATTAAAGGACAAAAAACAGCTAAACGTGCATTAGAAGTTTGCGCAGCTGGGCGGCATAACCTTT
TATTTGTCGGTCCTCCTGGTGCCGGAAAGTCTATGTTAGCACAACGCTTACCTTCCATTTTGCCACCTCTTGATAGCCGT
GAACTCTTAGATGTTTCTCTGATTGCTTCTATTACGGGAGAAACCATACAGAATACCATTTCACTTCACTGCCCCTTTCG
CGCTCCGCATCATTCTGCTTCCATGGCTGCAATGATCGGTGGTGGACTTAAAGCACGACCGGGAGAAGTCTCGCTTGCAC
ATAATGGTGTCTTATTTCTTGACGAATTACCGGAATTTTCTCCACAGGTCCTCGATTCTCTTCGTCAACCTTTAGAAAGC
GGAGAATGTGTTATCGCCCGCGCTAACCACCATATCAGCTATCCTGCCCGTATCCAACTCATTGCCGCGATGAACCCTTG
TCGATGTGGCATGGCAGGCGAAAAAAATCATGTTTGCGCAAAAGGAATACGCTGTCAAATCGATTATCAATCCCGTATTT
CTGGTCCTTTGCTCGACCGAATTGATTTACGAATTGATGTCCCTGCTTTAACAGCTATGGATCTTATGCAACCAGAACAA
TCAGAAAAAAGCTGCGCTGTTGCAAAACGCGTCGCACGGTGTCGTACCATTCAAACCAAACGCTTTACTAAACTAGGGCT
TGATCATATTCGCACTAACGGTGATTGCCCAGCCAAAATTATCGAACAAATTGCTATTCCTGATAAAAATGCGGCTACAC
TCTTACGGGATGTGAGCGAAAAGATGCACCTTTCTGCACGCGCCTATCATCGTATTCTCAAAGTTGCACGCACCATTGCT
GATCTCGACGAAGCAGACTATCTCTCACGCCATCATCTCGCGGAAGCCATTTCTTATCGATTGGGCACTGAAAGATTAAC
AGCTCTTACCTAA

Upstream 100 bases:

>100_bases
ATATGTAGACCTCTTCTCACAAAAGACTATACGGACACTTCTTGATTTTTATGTGCAGATATGATTGTCTCGCTCAAATC
ACAAGTTGGGGAGAAAACTG

Downstream 100 bases:

>100_bases
AAAAGCACGCTTCAATAAAAACTGATTGGAAAATAACGTAGATAAAGTTCTGTAAGCTTACCATCATCCTCTAGAGATTT
CAGAGCATAATTGAGTATAT

Product: competence protein comM

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 510; Mature: 510

Protein sequence:

>510_residues
MIACVTTVAFRGLEAVPVDVQVMISSGKIGMAIVGLPDKAIAESRERVQAAFHACGLSMPNKRVTINLAPADLPKEGSHY
DLPIAVGLMLAMGLLPPDVEQDYIILGELSLDGSLTAVNGVLPAAMTALSCDKGLICPYQCGPEAAWANAEMNILAPETL
LTMVNHFKGTQIQKRPQPRQYTIQNELPDLCEIKGQKTAKRALEVCAAGRHNLLFVGPPGAGKSMLAQRLPSILPPLDSR
ELLDVSLIASITGETIQNTISLHCPFRAPHHSASMAAMIGGGLKARPGEVSLAHNGVLFLDELPEFSPQVLDSLRQPLES
GECVIARANHHISYPARIQLIAAMNPCRCGMAGEKNHVCAKGIRCQIDYQSRISGPLLDRIDLRIDVPALTAMDLMQPEQ
SEKSCAVAKRVARCRTIQTKRFTKLGLDHIRTNGDCPAKIIEQIAIPDKNAATLLRDVSEKMHLSARAYHRILKVARTIA
DLDEADYLSRHHLAEAISYRLGTERLTALT

Sequences:

>Translated_510_residues
MIACVTTVAFRGLEAVPVDVQVMISSGKIGMAIVGLPDKAIAESRERVQAAFHACGLSMPNKRVTINLAPADLPKEGSHY
DLPIAVGLMLAMGLLPPDVEQDYIILGELSLDGSLTAVNGVLPAAMTALSCDKGLICPYQCGPEAAWANAEMNILAPETL
LTMVNHFKGTQIQKRPQPRQYTIQNELPDLCEIKGQKTAKRALEVCAAGRHNLLFVGPPGAGKSMLAQRLPSILPPLDSR
ELLDVSLIASITGETIQNTISLHCPFRAPHHSASMAAMIGGGLKARPGEVSLAHNGVLFLDELPEFSPQVLDSLRQPLES
GECVIARANHHISYPARIQLIAAMNPCRCGMAGEKNHVCAKGIRCQIDYQSRISGPLLDRIDLRIDVPALTAMDLMQPEQ
SEKSCAVAKRVARCRTIQTKRFTKLGLDHIRTNGDCPAKIIEQIAIPDKNAATLLRDVSEKMHLSARAYHRILKVARTIA
DLDEADYLSRHHLAEAISYRLGTERLTALT
>Mature_510_residues
MIACVTTVAFRGLEAVPVDVQVMISSGKIGMAIVGLPDKAIAESRERVQAAFHACGLSMPNKRVTINLAPADLPKEGSHY
DLPIAVGLMLAMGLLPPDVEQDYIILGELSLDGSLTAVNGVLPAAMTALSCDKGLICPYQCGPEAAWANAEMNILAPETL
LTMVNHFKGTQIQKRPQPRQYTIQNELPDLCEIKGQKTAKRALEVCAAGRHNLLFVGPPGAGKSMLAQRLPSILPPLDSR
ELLDVSLIASITGETIQNTISLHCPFRAPHHSASMAAMIGGGLKARPGEVSLAHNGVLFLDELPEFSPQVLDSLRQPLES
GECVIARANHHISYPARIQLIAAMNPCRCGMAGEKNHVCAKGIRCQIDYQSRISGPLLDRIDLRIDVPALTAMDLMQPEQ
SEKSCAVAKRVARCRTIQTKRFTKLGLDHIRTNGDCPAKIIEQIAIPDKNAATLLRDVSEKMHLSARAYHRILKVARTIA
DLDEADYLSRHHLAEAISYRLGTERLTALT

Specific function: Induced during competence development. Not needed for DNA uptake. May be involved in a recombination step [H]

COG id: COG0606

COG function: function code O; Predicted ATPase with chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily [H]

Homologues:

Organism=Escherichia coli, GI145693202, Length=501, Percent_Identity=41.7165668662675, Blast_Score=363, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001208
- InterPro:   IPR004482
- InterPro:   IPR000523
- InterPro:   IPR020568 [H]

Pfam domain/function: PF01078 Mg_chelatase [H]

EC number: NA

Molecular weight: Translated: 55294; Mature: 55294

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIACVTTVAFRGLEAVPVDVQVMISSGKIGMAIVGLPDKAIAESRERVQAAFHACGLSMP
CEEEEEHHHHCCCCCCCCEEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCC
NKRVTINLAPADLPKEGSHYDLPIAVGLMLAMGLLPPDVEQDYIILGELSLDGSLTAVNG
CCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCHHHHH
VLPAAMTALSCDKGLICPYQCGPEAAWANAEMNILAPETLLTMVNHFKGTQIQKRPQPRQ
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHCCCCCCCCCCCCCC
YTIQNELPDLCEIKGQKTAKRALEVCAAGRHNLLFVGPPGAGKSMLAQRLPSILPPLDSR
EEHHHCCCHHHHCCCCHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCC
ELLDVSLIASITGETIQNTISLHCPFRAPHHSASMAAMIGGGLKARPGEVSLAHNGVLFL
HHHHHHHHHHHCCHHHHCEEEEECCCCCCCCCCHHHHHHCCCCCCCCCCEEEECCCEEEE
DELPEFSPQVLDSLRQPLESGECVIARANHHISYPARIQLIAAMNPCRCGMAGEKNHVCA
CCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEC
KGIRCQIDYQSRISGPLLDRIDLRIDVPALTAMDLMQPEQSEKSCAVAKRVARCRTIQTK
CCCEEEEEHHHHCCCCCHHCCCEEEECCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
RFTKLGLDHIRTNGDCPAKIIEQIAIPDKNAATLLRDVSEKMHLSARAYHRILKVARTIA
HHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLDEADYLSRHHLAEAISYRLGTERLTALT
HCHHHHHHHHHHHHHHHHHHCCCHHHHCCC
>Mature Secondary Structure
MIACVTTVAFRGLEAVPVDVQVMISSGKIGMAIVGLPDKAIAESRERVQAAFHACGLSMP
CEEEEEHHHHCCCCCCCCEEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCC
NKRVTINLAPADLPKEGSHYDLPIAVGLMLAMGLLPPDVEQDYIILGELSLDGSLTAVNG
CCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCHHHHH
VLPAAMTALSCDKGLICPYQCGPEAAWANAEMNILAPETLLTMVNHFKGTQIQKRPQPRQ
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHCCCCCCCCCCCCCC
YTIQNELPDLCEIKGQKTAKRALEVCAAGRHNLLFVGPPGAGKSMLAQRLPSILPPLDSR
EEHHHCCCHHHHCCCCHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCC
ELLDVSLIASITGETIQNTISLHCPFRAPHHSASMAAMIGGGLKARPGEVSLAHNGVLFL
HHHHHHHHHHHCCHHHHCEEEEECCCCCCCCCCHHHHHHCCCCCCCCCCEEEECCCEEEE
DELPEFSPQVLDSLRQPLESGECVIARANHHISYPARIQLIAAMNPCRCGMAGEKNHVCA
CCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEC
KGIRCQIDYQSRISGPLLDRIDLRIDVPALTAMDLMQPEQSEKSCAVAKRVARCRTIQTK
CCCEEEEEHHHHCCCCCHHCCCEEEECCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
RFTKLGLDHIRTNGDCPAKIIEQIAIPDKNAATLLRDVSEKMHLSARAYHRILKVARTIA
HHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLDEADYLSRHHLAEAISYRLGTERLTALT
HCHHHHHHHHHHHHHHHHHHCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 9457884 [H]