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The map label for this gene is divL [H]

Identifier: 49474858

GI number: 49474858

Start: 37929

End: 40394

Strand: Reverse

Name: divL [H]

Synonym: BH00300

Alternate gene names: 49474858

Gene position: 40394-37929 (Counterclockwise)

Preceding gene: 49474859

Following gene: 49474857

Centisome position: 2.09

GC content: 40.23

Gene sequence:

>2466_bases
GTGCTCAGCTTCGGTGACTATAACTCCAAAGAAAAAGCTCAAAAAATGATCCGAATCTGTACTCATATTTTTTGCTTTCT
TTTTCTTTTTTTTCCAACATGTGCTGCTGCTCAGTTATTGGAAACATATCTACCGTCTACCTTTACTTTGCCAGATGGTC
CATGGCTTCTCTTAGCGCTCTGCGGAGGAATCTCTTGTGCCTCACTTTTCACGTGTATGGCCGTTATTATGCGTGCGAAA
AAAACGTTACAAAAGCCTCTGCAGACATTTCAAACAGATCTTTCTGAAAAACTTAAATATTATGAATGGCTTCTGGAAGA
AACCGGACAGTATCTTCTTATTTGGGAAAACCCAACGGCTTTACCTCGTGTGGTTGGCAACATTCCAACATTGCAAAAAG
TGGGAATTCATCAACAAGATTTTCAGCGTTTCGAATTCTGGCTTGAAGAAAATTCTCTGCGGGAACTTGATTACGCATTA
AAGCAATTACGTTACAAGTCTCATCCTTTTGAACTTTCTCTTTTCACCAAGAATAATATGCTGTTGCATGTTACAGGCGT
TATTGCTGGAACAGTAGCCATTGCACGCTTTCAAGACATCTCACTACAACAAAGCGAAAATGCTCGTTTACAGAAAAATA
TTGCAAGAATCCTTACCGAACTGAGAATGCAGCGTAACCTTCTCGATGTTATTCAAGAACCAGTCTGGATAAAAGATAGT
GAAGGAAAAATTTGCTTTATCAACCGCGCCTTTAGAGAAATAACAGGCTTTCGAGAAGGCAGTAACGAAGTAGTTGACCT
TTTCAATGAAACAACACAACGCAAAACAGATGAAACAGAAACCGTTTTTCAAGAGCACGTTCATACGGTCCTTGATGGAG
AACGGCACCGCTTTCATCTCACACGGATTACAACAGCCGAAGGGATGGCGGCTTTTGCCCGTGATGATAGTGCATATGAA
AATCTTGCCAATGAACTAAGACGTGTTTTTCAAAACCATTGTGAAACACTTGATCAAATTTCAACAGCTGTAGCTGTTTT
CGATAGCAATCAAAAATTAAAATTCTGCAACCATGCCTTTAAAATTTTATGGCCCTTAGAGAATTCCTTTCTAGAAAGTG
AACCAAGCCATACATTGTTTCTTGAACGTTTGCGTGAAAAAGGGCTCATTGGTGAACACCCGGATTGGCGCACTTGGAAA
GAAGAACTTTTAAAAGCTTACCGGCAAACGGAATCAAATCAACAAATTTGGAATCTTCCAGATGGGCGCACAGTGCGTGT
CATTTCTAGTCCTCACCCACAAGGAGGTGTCACTTGGCTTTACGAAAATCTCACAGAAAAAATTGATCTTGAACAGCGCT
ATAATACACTCATTAAAATACAAGGCGAAACACTTGATAAACTTTCAGAAGGAGTGGTGGTCTTTGGCACTGATGGATGC
CTTCGTTTATCAAATCCTGCTTTATCAAAATTATGGTCTCTACCCTATAATTTATTGGTAGAAGGCACCCATATTACACA
ATTACAAAGTTATTGTTCACCCCTAACTTTGAGACAAGAATGGGACTGGTTCACCAAATTTATTACCGGTTTTGCTGAAG
AACGGGATACATATTCAGGTCGTATGGACCTCAAAAATGGCATGATCATTGATTACACATTGGTCCCGCTTCCTAATGGA
GAGACCATGCTTACTTTCGTGAATGTTACGGACACTGTTCATGTCGCGCGTGCTCTTCAAGAGAAAAATGAAGCTTTGGA
AAGTGCTGATCGTTTGCGGAATGAATTTGTCCAACATGTTTCCTATGAATTGCGTACACCCCTCACCAATATTATTGGAT
TTTCCGATATTTTACGCGATCAAATTTTTGGTCCTATCAATGAACGCCAACAGGAATATCTTGGACACATTCATTCAGAA
TCAGGCTCTCTTTTGAATATTGTGAATGATATTCTTGACCTTGCAACCCTTGATGCTGGTATTATGGAGCTGGACATAAA
ACCGGTTAATATTGCCGATGCTATGGTGCAAGCAGTAGCACGTGTGGAAGAGCGTCTTAATGGACGCCATATTACGCTTT
TACAACAAATTTCTCCTTCCTTAAACTTTATTTCTGTAGATGCAACACGTTTGCACCAAATCTTTGTGAATGTCCTCAGC
AATGCTATTAATTTTGCAACGGAAGCAAGCACCATTGAATTTTGTGCCGAAGAAAAAGATGATGACATCGTTTTCAGTGT
TCACAATGAGGGATCCGATATTCCAGAAGATATCCTTGATCGCATTTTTAAACGCTTTTCTTCCCATTCACATCATGGTG
GGCGTGCGGGAGCAGGTCTTGGCCTTTCTCTTGTCAAAAGCTTTGTTGAGCTCCACGGAGGGCGCGTTGAAATTTTCACC
GGTACAGGACAAGGAACAACAGTTAAATGCTTCTTTCCAATTTCCAAAGAAGATAAAGTTTTTTAG

Upstream 100 bases:

>100_bases
CAAGCTGCCTATATTGGAGTTACTCCACAAGGACCTTATAAACCAGACCATTATCGTTATTAAATGTTTCCTTGGGATAA
AAGAAAAAGGAAAACGCATC

Downstream 100 bases:

>100_bases
TCTTATCCTTTATTATGATAAAAACTCTTTCTCATTCACTTCATGGAAATCTTAATGAATTTTAGTTTTTTTCTTGAAAA
TGAAGAAGCAACCAAGCTTT

Product: sensor histidine kinase protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 821; Mature: 821

Protein sequence:

>821_residues
MLSFGDYNSKEKAQKMIRICTHIFCFLFLFFPTCAAAQLLETYLPSTFTLPDGPWLLLALCGGISCASLFTCMAVIMRAK
KTLQKPLQTFQTDLSEKLKYYEWLLEETGQYLLIWENPTALPRVVGNIPTLQKVGIHQQDFQRFEFWLEENSLRELDYAL
KQLRYKSHPFELSLFTKNNMLLHVTGVIAGTVAIARFQDISLQQSENARLQKNIARILTELRMQRNLLDVIQEPVWIKDS
EGKICFINRAFREITGFREGSNEVVDLFNETTQRKTDETETVFQEHVHTVLDGERHRFHLTRITTAEGMAAFARDDSAYE
NLANELRRVFQNHCETLDQISTAVAVFDSNQKLKFCNHAFKILWPLENSFLESEPSHTLFLERLREKGLIGEHPDWRTWK
EELLKAYRQTESNQQIWNLPDGRTVRVISSPHPQGGVTWLYENLTEKIDLEQRYNTLIKIQGETLDKLSEGVVVFGTDGC
LRLSNPALSKLWSLPYNLLVEGTHITQLQSYCSPLTLRQEWDWFTKFITGFAEERDTYSGRMDLKNGMIIDYTLVPLPNG
ETMLTFVNVTDTVHVARALQEKNEALESADRLRNEFVQHVSYELRTPLTNIIGFSDILRDQIFGPINERQQEYLGHIHSE
SGSLLNIVNDILDLATLDAGIMELDIKPVNIADAMVQAVARVEERLNGRHITLLQQISPSLNFISVDATRLHQIFVNVLS
NAINFATEASTIEFCAEEKDDDIVFSVHNEGSDIPEDILDRIFKRFSSHSHHGGRAGAGLGLSLVKSFVELHGGRVEIFT
GTGQGTTVKCFFPISKEDKVF

Sequences:

>Translated_821_residues
MLSFGDYNSKEKAQKMIRICTHIFCFLFLFFPTCAAAQLLETYLPSTFTLPDGPWLLLALCGGISCASLFTCMAVIMRAK
KTLQKPLQTFQTDLSEKLKYYEWLLEETGQYLLIWENPTALPRVVGNIPTLQKVGIHQQDFQRFEFWLEENSLRELDYAL
KQLRYKSHPFELSLFTKNNMLLHVTGVIAGTVAIARFQDISLQQSENARLQKNIARILTELRMQRNLLDVIQEPVWIKDS
EGKICFINRAFREITGFREGSNEVVDLFNETTQRKTDETETVFQEHVHTVLDGERHRFHLTRITTAEGMAAFARDDSAYE
NLANELRRVFQNHCETLDQISTAVAVFDSNQKLKFCNHAFKILWPLENSFLESEPSHTLFLERLREKGLIGEHPDWRTWK
EELLKAYRQTESNQQIWNLPDGRTVRVISSPHPQGGVTWLYENLTEKIDLEQRYNTLIKIQGETLDKLSEGVVVFGTDGC
LRLSNPALSKLWSLPYNLLVEGTHITQLQSYCSPLTLRQEWDWFTKFITGFAEERDTYSGRMDLKNGMIIDYTLVPLPNG
ETMLTFVNVTDTVHVARALQEKNEALESADRLRNEFVQHVSYELRTPLTNIIGFSDILRDQIFGPINERQQEYLGHIHSE
SGSLLNIVNDILDLATLDAGIMELDIKPVNIADAMVQAVARVEERLNGRHITLLQQISPSLNFISVDATRLHQIFVNVLS
NAINFATEASTIEFCAEEKDDDIVFSVHNEGSDIPEDILDRIFKRFSSHSHHGGRAGAGLGLSLVKSFVELHGGRVEIFT
GTGQGTTVKCFFPISKEDKVF
>Mature_821_residues
MLSFGDYNSKEKAQKMIRICTHIFCFLFLFFPTCAAAQLLETYLPSTFTLPDGPWLLLALCGGISCASLFTCMAVIMRAK
KTLQKPLQTFQTDLSEKLKYYEWLLEETGQYLLIWENPTALPRVVGNIPTLQKVGIHQQDFQRFEFWLEENSLRELDYAL
KQLRYKSHPFELSLFTKNNMLLHVTGVIAGTVAIARFQDISLQQSENARLQKNIARILTELRMQRNLLDVIQEPVWIKDS
EGKICFINRAFREITGFREGSNEVVDLFNETTQRKTDETETVFQEHVHTVLDGERHRFHLTRITTAEGMAAFARDDSAYE
NLANELRRVFQNHCETLDQISTAVAVFDSNQKLKFCNHAFKILWPLENSFLESEPSHTLFLERLREKGLIGEHPDWRTWK
EELLKAYRQTESNQQIWNLPDGRTVRVISSPHPQGGVTWLYENLTEKIDLEQRYNTLIKIQGETLDKLSEGVVVFGTDGC
LRLSNPALSKLWSLPYNLLVEGTHITQLQSYCSPLTLRQEWDWFTKFITGFAEERDTYSGRMDLKNGMIIDYTLVPLPNG
ETMLTFVNVTDTVHVARALQEKNEALESADRLRNEFVQHVSYELRTPLTNIIGFSDILRDQIFGPINERQQEYLGHIHSE
SGSLLNIVNDILDLATLDAGIMELDIKPVNIADAMVQAVARVEERLNGRHITLLQQISPSLNFISVDATRLHQIFVNVLS
NAINFATEASTIEFCAEEKDDDIVFSVHNEGSDIPEDILDRIFKRFSSHSHHGGRAGAGLGLSLVKSFVELHGGRVEIFT
GTGQGTTVKCFFPISKEDKVF

Specific function: Required for cell division and growth. It catalyzes the phosphorylation of CtrA and activates transcription in vitro of the cell cycle-regulated fliF promoter [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=230, Percent_Identity=31.7391304347826, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1788393, Length=260, Percent_Identity=25, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1788713, Length=302, Percent_Identity=26.8211920529801, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI1789149, Length=238, Percent_Identity=30.672268907563, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1790861, Length=251, Percent_Identity=28.2868525896414, Blast_Score=91, Evalue=4e-19,
Organism=Escherichia coli, GI145693157, Length=256, Percent_Identity=26.5625, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI87082128, Length=245, Percent_Identity=25.3061224489796, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1786912, Length=293, Percent_Identity=24.5733788395904, Blast_Score=87, Evalue=6e-18,
Organism=Escherichia coli, GI87081816, Length=238, Percent_Identity=29.4117647058824, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1790436, Length=216, Percent_Identity=26.3888888888889, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1786600, Length=242, Percent_Identity=27.6859504132231, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1788549, Length=423, Percent_Identity=23.1678486997636, Blast_Score=76, Evalue=9e-15,
Organism=Escherichia coli, GI1786783, Length=235, Percent_Identity=27.2340425531915, Blast_Score=67, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 93901; Mature: 93901

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSFGDYNSKEKAQKMIRICTHIFCFLFLFFPTCAAAQLLETYLPSTFTLPDGPWLLLAL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHH
CGGISCASLFTCMAVIMRAKKTLQKPLQTFQTDLSEKLKYYEWLLEETGQYLLIWENPTA
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCH
LPRVVGNIPTLQKVGIHQQDFQRFEFWLEENSLRELDYALKQLRYKSHPFELSLFTKNNM
HHHHHCCCCCHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEEEECCCE
LLHVTGVIAGTVAIARFQDISLQQSENARLQKNIARILTELRMQRNLLDVIQEPVWIKDS
EEEEHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECC
EGKICFINRAFREITGFREGSNEVVDLFNETTQRKTDETETVFQEHVHTVLDGERHRFHL
CCCEEEEEHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEE
TRITTAEGMAAFARDDSAYENLANELRRVFQNHCETLDQISTAVAVFDSNQKLKFCNHAF
EEEECHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHCCHH
KILWPLENSFLESEPSHTLFLERLREKGLIGEHPDWRTWKEELLKAYRQTESNQQIWNLP
EEEECCCHHHHCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECC
DGRTVRVISSPHPQGGVTWLYENLTEKIDLEQRYNTLIKIQGETLDKLSEGVVVFGTDGC
CCCEEEEEECCCCCCCHHHHHHHHHHHCCHHHHCCEEEEECCCHHHHHHCCEEEEECCCC
LRLSNPALSKLWSLPYNLLVEGTHITQLQSYCSPLTLRQEWDWFTKFITGFAEERDTYSG
EEECCHHHHHHHHCCHHHEECCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
RMDLKNGMIIDYTLVPLPNGETMLTFVNVTDTVHVARALQEKNEALESADRLRNEFVQHV
CEECCCCEEEEEEEEECCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SYELRTPLTNIIGFSDILRDQIFGPINERQQEYLGHIHSESGSLLNIVNDILDLATLDAG
HHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
IMELDIKPVNIADAMVQAVARVEERLNGRHITLLQQISPSLNFISVDATRLHQIFVNVLS
CEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEHHHCCCCCCEEECCHHHHHHHHHHHHH
NAINFATEASTIEFCAEEKDDDIVFSVHNEGSDIPEDILDRIFKRFSSHSHHGGRAGAGL
HHHHHHHCHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCC
GLSLVKSFVELHGGRVEIFTGTGQGTTVKCFFPISKEDKVF
CHHHHHHHHHHCCCEEEEEECCCCCCEEEEEEECCCCCCCC
>Mature Secondary Structure
MLSFGDYNSKEKAQKMIRICTHIFCFLFLFFPTCAAAQLLETYLPSTFTLPDGPWLLLAL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHH
CGGISCASLFTCMAVIMRAKKTLQKPLQTFQTDLSEKLKYYEWLLEETGQYLLIWENPTA
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCH
LPRVVGNIPTLQKVGIHQQDFQRFEFWLEENSLRELDYALKQLRYKSHPFELSLFTKNNM
HHHHHCCCCCHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEEEECCCE
LLHVTGVIAGTVAIARFQDISLQQSENARLQKNIARILTELRMQRNLLDVIQEPVWIKDS
EEEEHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECC
EGKICFINRAFREITGFREGSNEVVDLFNETTQRKTDETETVFQEHVHTVLDGERHRFHL
CCCEEEEEHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEE
TRITTAEGMAAFARDDSAYENLANELRRVFQNHCETLDQISTAVAVFDSNQKLKFCNHAF
EEEECHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHCCHH
KILWPLENSFLESEPSHTLFLERLREKGLIGEHPDWRTWKEELLKAYRQTESNQQIWNLP
EEEECCCHHHHCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECC
DGRTVRVISSPHPQGGVTWLYENLTEKIDLEQRYNTLIKIQGETLDKLSEGVVVFGTDGC
CCCEEEEEECCCCCCCHHHHHHHHHHHCCHHHHCCEEEEECCCHHHHHHCCEEEEECCCC
LRLSNPALSKLWSLPYNLLVEGTHITQLQSYCSPLTLRQEWDWFTKFITGFAEERDTYSG
EEECCHHHHHHHHCCHHHEECCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
RMDLKNGMIIDYTLVPLPNGETMLTFVNVTDTVHVARALQEKNEALESADRLRNEFVQHV
CEECCCCEEEEEEEEECCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SYELRTPLTNIIGFSDILRDQIFGPINERQQEYLGHIHSESGSLLNIVNDILDLATLDAG
HHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
IMELDIKPVNIADAMVQAVARVEERLNGRHITLLQQISPSLNFISVDATRLHQIFVNVLS
CEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEHHHCCCCCCEEECCHHHHHHHHHHHHH
NAINFATEASTIEFCAEEKDDDIVFSVHNEGSDIPEDILDRIFKRFSSHSHHGGRAGAGL
HHHHHHHCHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCC
GLSLVKSFVELHGGRVEIFTGTGQGTTVKCFFPISKEDKVF
CHHHHHHHHHHCCCEEEEEECCCCCCEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10557274; 11259647 [H]