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The map label for this gene is qor [C]

Identifier: 49186311

GI number: 49186311

Start: 3271721

End: 3272719

Strand: Direct

Name: qor [C]

Synonym: BAS3306

Alternate gene names: 49186311

Gene position: 3271721-3272719 (Clockwise)

Preceding gene: 49186310

Following gene: 49186312

Centisome position: 62.57

GC content: 34.33

Gene sequence:

>999_bases
ATGAAAGCGATGATAATTGATAAGTATGGAAAAGTCCCAATGCGTATGGCCGAGGTACCTATTCCTGAAATAAATGAGCA
TGAAGTGCTCGCAGAAATTCATGCAGCTAGTATTAACCCAATTGATTTTAAAATACGCGATGGAAAAGTAAAGATGTTAC
TGAAATATGAAATGCCCCTAATCCTTGGGAATGACTTTGCCGGTGTCATCATAAAGGTTGGATCAAAAGTAACTCGTTTT
AAAATCGGTGATGAAATATATGCACGTCCAAGAAAAAATAAGATTGGTACTTTCGCGGAGTATATAGCTATTCATGAAGA
TGATATAGCTTTAAAACCGAAAAATTTAAGTTTTGAAGAAGCTGCTTCAATTCCACTTGTTGGCTTAACATCATATCAAG
CATTACATGACATTATGCAATTACAAAAAGATCAAAAGATTTTAATTCACGCTGGATCTGGTGGTGTTGGTACTTTCGCA
ATTCAGCTAGCAAAAATAATGGGTGCTACCGTTACAACAACTGCTAGTGAAGCTGGTCCCGATTTAGTAAAGTCTCTTGG
AGCAGATCAAATTATTAATTACAAAACAGAAAAATTTGAAGAAATACTAAAAGATTATGATGCAGTATTTGATACCATTG
GTGGTACAACACTTGAAAAATCATTCGATATTATAAAAAGCGGCGGCAACATTGTTTCCGTTTCAGGAATACCAAATGCT
CGTTTCAGTAAAGAATTTGGTTCTGGATTTTTTAAAACATTCTTATTTTCATTAGCAAGTAAAAAACTTACTGCACTTGA
AAAAAAGCATAATGCTCAATATTCATTTTTATTTATGAAGCCAAGCGGAGATCAATTACGTACTATCGCAAACTATATTG
AAGCCGGAAAAATCAAACCGGTAATCGATCGAGTTTTCCCTTTTGAAGATGCGCAAAAAGCAATGGAATATTCAGAGGCC
GGAAGAGCAAAAGGAAAAATAATTGTGAAAATGAAATAA

Upstream 100 bases:

>100_bases
TTATATTGATATACGTACAAAATTAAGTTTATTAAAAAATCTTGTATTAGATATCGAAAAGCTATTGCACAACTTTTATT
AAAATGTGGAGGTATAAGAA

Downstream 100 bases:

>100_bases
TAATAAAGACTCCATTTTCTTAAGATGGGGTCTTTATATTTACTGTTAAATAGACATAGTGCAGTGAAGTCCTTACAATA
GATTGCAAGGGGAAATATCA

Product: zinc-containing alcohol dehydrogenase

Products: aldehyde; ketone; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MKAMIIDKYGKVPMRMAEVPIPEINEHEVLAEIHAASINPIDFKIRDGKVKMLLKYEMPLILGNDFAGVIIKVGSKVTRF
KIGDEIYARPRKNKIGTFAEYIAIHEDDIALKPKNLSFEEAASIPLVGLTSYQALHDIMQLQKDQKILIHAGSGGVGTFA
IQLAKIMGATVTTTASEAGPDLVKSLGADQIINYKTEKFEEILKDYDAVFDTIGGTTLEKSFDIIKSGGNIVSVSGIPNA
RFSKEFGSGFFKTFLFSLASKKLTALEKKHNAQYSFLFMKPSGDQLRTIANYIEAGKIKPVIDRVFPFEDAQKAMEYSEA
GRAKGKIIVKMK

Sequences:

>Translated_332_residues
MKAMIIDKYGKVPMRMAEVPIPEINEHEVLAEIHAASINPIDFKIRDGKVKMLLKYEMPLILGNDFAGVIIKVGSKVTRF
KIGDEIYARPRKNKIGTFAEYIAIHEDDIALKPKNLSFEEAASIPLVGLTSYQALHDIMQLQKDQKILIHAGSGGVGTFA
IQLAKIMGATVTTTASEAGPDLVKSLGADQIINYKTEKFEEILKDYDAVFDTIGGTTLEKSFDIIKSGGNIVSVSGIPNA
RFSKEFGSGFFKTFLFSLASKKLTALEKKHNAQYSFLFMKPSGDQLRTIANYIEAGKIKPVIDRVFPFEDAQKAMEYSEA
GRAKGKIIVKMK
>Mature_332_residues
MKAMIIDKYGKVPMRMAEVPIPEINEHEVLAEIHAASINPIDFKIRDGKVKMLLKYEMPLILGNDFAGVIIKVGSKVTRF
KIGDEIYARPRKNKIGTFAEYIAIHEDDIALKPKNLSFEEAASIPLVGLTSYQALHDIMQLQKDQKILIHAGSGGVGTFA
IQLAKIMGATVTTTASEAGPDLVKSLGADQIINYKTEKFEEILKDYDAVFDTIGGTTLEKSFDIIKSGGNIVSVSGIPNA
RFSKEFGSGFFKTFLFSLASKKLTALEKKHNAQYSFLFMKPSGDQLRTIANYIEAGKIKPVIDRVFPFEDAQKAMEYSEA
GRAKGKIIVKMK

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI47519420, Length=356, Percent_Identity=34.8314606741573, Blast_Score=198, Evalue=7e-51,
Organism=Homo sapiens, GI22538446, Length=344, Percent_Identity=29.0697674418605, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI22538444, Length=344, Percent_Identity=29.0697674418605, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI194239674, Length=325, Percent_Identity=28.3076923076923, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI13236495, Length=325, Percent_Identity=28.3076923076923, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI18379349, Length=313, Percent_Identity=29.3929712460064, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI194239676, Length=313, Percent_Identity=28.1150159744409, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI24308257, Length=354, Percent_Identity=26.271186440678, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI67078404, Length=335, Percent_Identity=24.4776119402985, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI28557745, Length=334, Percent_Identity=25.748502994012, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI67078406, Length=298, Percent_Identity=25.8389261744966, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI90669511, Length=157, Percent_Identity=30.5732484076433, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI156627571, Length=345, Percent_Identity=25.2173913043478, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI1790485, Length=317, Percent_Identity=30.2839116719243, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1790045, Length=353, Percent_Identity=22.0963172804533, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789651, Length=246, Percent_Identity=26.4227642276423, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71987554, Length=366, Percent_Identity=29.5081967213115, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17507255, Length=241, Percent_Identity=29.4605809128631, Blast_Score=104, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI71988145, Length=222, Percent_Identity=29.2792792792793, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17536829, Length=305, Percent_Identity=27.2131147540984, Blast_Score=81, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17562876, Length=267, Percent_Identity=28.0898876404494, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17556000, Length=347, Percent_Identity=22.7665706051873, Blast_Score=71, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17562878, Length=223, Percent_Identity=29.1479820627803, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323801, Length=349, Percent_Identity=26.9340974212034, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6319520, Length=347, Percent_Identity=27.0893371757925, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320948, Length=369, Percent_Identity=24.6612466124661, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6324195, Length=243, Percent_Identity=33.3333333333333, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6319401, Length=262, Percent_Identity=26.7175572519084, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319945, Length=242, Percent_Identity=33.0578512396694, Blast_Score=70, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6323493, Length=242, Percent_Identity=31.404958677686, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24581341, Length=364, Percent_Identity=28.021978021978, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24581339, Length=364, Percent_Identity=28.021978021978, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI45550423, Length=254, Percent_Identity=24.4094488188976, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI221330659, Length=233, Percent_Identity=27.8969957081545, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI19920632, Length=233, Percent_Identity=27.8969957081545, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24581345, Length=231, Percent_Identity=25.974025974026, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR014182
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: 1.1.1.1

Molecular weight: Translated: 36662; Mature: 36662

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAMIIDKYGKVPMRMAEVPIPEINEHEVLAEIHAASINPIDFKIRDGKVKMLLKYEMPL
CCEEEEECCCCCCCCHHCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCEEEEEEECCCE
ILGNDFAGVIIKVGSKVTRFKIGDEIYARPRKNKIGTFAEYIAIHEDDIALKPKNLSFEE
EECCCCCEEEEEECCCEEEEEECCHHHCCCCCCCCHHHHHHHEEECCCCEECCCCCCHHH
AASIPLVGLTSYQALHDIMQLQKDQKILIHAGSGGVGTFAIQLAKIMGATVTTTASEAGP
HCCCCEEECHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCEEEECCCCCCH
DLVKSLGADQIINYKTEKFEEILKDYDAVFDTIGGTTLEKSFDIIKSGGNIVSVSGIPNA
HHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEECCCCCC
RFSKEFGSGFFKTFLFSLASKKLTALEKKHNAQYSFLFMKPSGDQLRTIANYIEAGKIKP
CHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHCCCCCH
VIDRVFPFEDAQKAMEYSEAGRAKGKIIVKMK
HHHHHCCCHHHHHHHHHHHCCCCCCEEEEEEC
>Mature Secondary Structure
MKAMIIDKYGKVPMRMAEVPIPEINEHEVLAEIHAASINPIDFKIRDGKVKMLLKYEMPL
CCEEEEECCCCCCCCHHCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCEEEEEEECCCE
ILGNDFAGVIIKVGSKVTRFKIGDEIYARPRKNKIGTFAEYIAIHEDDIALKPKNLSFEE
EECCCCCEEEEEECCCEEEEEECCHHHCCCCCCCCHHHHHHHEEECCCCEECCCCCCHHH
AASIPLVGLTSYQALHDIMQLQKDQKILIHAGSGGVGTFAIQLAKIMGATVTTTASEAGP
HCCCCEEECHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCEEEECCCCCCH
DLVKSLGADQIINYKTEKFEEILKDYDAVFDTIGGTTLEKSFDIIKSGGNIVSVSGIPNA
HHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEECCCCCC
RFSKEFGSGFFKTFLFSLASKKLTALEKKHNAQYSFLFMKPSGDQLRTIANYIEAGKIKP
CHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHCCCCCH
VIDRVFPFEDAQKAMEYSEAGRAKGKIIVKMK
HHHHHCCCHHHHHHHHHHHCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: alcohol; NAD+

Specific reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA