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The map label for this gene is ilvH [H]

Identifier: 49184326

GI number: 49184326

Start: 1342068

End: 1342577

Strand: Direct

Name: ilvH [H]

Synonym: BAS1309

Alternate gene names: 49184326

Gene position: 1342068-1342577 (Clockwise)

Preceding gene: 49184325

Following gene: 49184327

Centisome position: 25.67

GC content: 36.47

Gene sequence:

>510_bases
GTGAAGAGAATTGTTACAGCAACAGTTCGAAATCAAAGTGGTGTGTTAAACCGAATTACAGGTGTTATGACACGAAGACA
TTTTAATATTGAAAGTATTTCAGTAGGTCATACGGAATCATCGGACATATCGCGGATGACGATTGTTGTACACGTTGAAA
ATGAACAGCAAGTAGAGCAGTTAATTAAACAACTTCATAAGCAAATTGATGTTTTGAAAGTATCAGATATTACAGAAGAA
GCGATGATTGCAAGAGAACTCGCACTTATTAAAGTAGCAACATCAGTAGCAAGAGCAGAATTATACAGTTTAATTGAACC
GTTTCGAGCCGCTGTAATAGATGTTGGGAAGGATTCCATAGTTGTGCAAGTAACAGGTACGCAGGAAAAAGTAGAAGCAT
TAATTGAATTACTTCGTCCATACGGTTTGAAAGAAATTGCAAGAACAGGGGTAACAGCCTTTACGCGTAGCATGAAAAAG
CAAGATAAGCAAGTAATGTTAATTCAATAA

Upstream 100 bases:

>100_bases
AACCAGTCGTAATTGATTGCCGTGTACTTCAATCAGAAAAGGTAATGCCGATGGTTGCGCCAGGGAAAGGTGTTCACCAA
ATGGAGGGAGTGGAAAAAAG

Downstream 100 bases:

>100_bases
TCATTTAAATATAGGGGGAAATGAAAATGGCAAAAGTTTATTATGAAAAAGATGTAACGGTAAATGTATTAAAGGAAAAG
AAAGTAGCAATCATTGGATA

Product: acetolactate synthase 3 regulatory subunit

Products: NA

Alternate protein names: Acetohydroxy-acid synthase small subunit; AHAS; ALS [H]

Number of amino acids: Translated: 169; Mature: 169

Protein sequence:

>169_residues
MKRIVTATVRNQSGVLNRITGVMTRRHFNIESISVGHTESSDISRMTIVVHVENEQQVEQLIKQLHKQIDVLKVSDITEE
AMIARELALIKVATSVARAELYSLIEPFRAAVIDVGKDSIVVQVTGTQEKVEALIELLRPYGLKEIARTGVTAFTRSMKK
QDKQVMLIQ

Sequences:

>Translated_169_residues
MKRIVTATVRNQSGVLNRITGVMTRRHFNIESISVGHTESSDISRMTIVVHVENEQQVEQLIKQLHKQIDVLKVSDITEE
AMIARELALIKVATSVARAELYSLIEPFRAAVIDVGKDSIVVQVTGTQEKVEALIELLRPYGLKEIARTGVTAFTRSMKK
QDKQVMLIQ
>Mature_169_residues
MKRIVTATVRNQSGVLNRITGVMTRRHFNIESISVGHTESSDISRMTIVVHVENEQQVEQLIKQLHKQIDVLKVSDITEE
AMIARELALIKVATSVARAELYSLIEPFRAAVIDVGKDSIVVQVTGTQEKVEALIELLRPYGLKEIARTGVTAFTRSMKK
QDKQVMLIQ

Specific function: Valine and isoleucine biosynthesis; first step. [C]

COG id: COG0440

COG function: function code E; Acetolactate synthase, small (regulatory) subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Escherichia coli, GI1786266, Length=161, Percent_Identity=39.1304347826087, Blast_Score=112, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6319837, Length=209, Percent_Identity=25.8373205741627, Blast_Score=79, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004789
- InterPro:   IPR019455
- InterPro:   IPR002912 [H]

Pfam domain/function: PF01842 ACT; PF10369 ALS_ss_C [H]

EC number: =2.2.1.6 [H]

Molecular weight: Translated: 18965; Mature: 18965

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRIVTATVRNQSGVLNRITGVMTRRHFNIESISVGHTESSDISRMTIVVHVENEQQVEQ
CCCEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEEEEEECCHHHHHH
LIKQLHKQIDVLKVSDITEEAMIARELALIKVATSVARAELYSLIEPFRAAVIDVGKDSI
HHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
VVQVTGTQEKVEALIELLRPYGLKEIARTGVTAFTRSMKKQDKQVMLIQ
EEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEC
>Mature Secondary Structure
MKRIVTATVRNQSGVLNRITGVMTRRHFNIESISVGHTESSDISRMTIVVHVENEQQVEQ
CCCEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEEEEEECCHHHHHH
LIKQLHKQIDVLKVSDITEEAMIARELALIKVATSVARAELYSLIEPFRAAVIDVGKDSI
HHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
VVQVTGTQEKVEALIELLRPYGLKEIARTGVTAFTRSMKKQDKQVMLIQ
EEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]