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The map label for this gene is kat [H]

Identifier: 49184096

GI number: 49184096

Start: 1129051

End: 1130517

Strand: Direct

Name: kat [H]

Synonym: BAS1076

Alternate gene names: 49184096

Gene position: 1129051-1130517 (Clockwise)

Preceding gene: 49184095

Following gene: 49184097

Centisome position: 21.59

GC content: 39.6

Gene sequence:

>1467_bases
ATGAATCCAAATAATCGCTTAACAACAAACCAAGGTGCTCCGGTCGGAGATAACCAAAATTCTCGTACAGCTGGTCGCCG
CGGACCAGTATTATTAGAAGACTATCATTTAGTAGAAAAACTAGCTCACTTTGATCGTGAACGTATTCCAGAGCGTGTTG
TGCATGCACGTGGTGCAGGTGCTCACGGTGTATTCGTAACGAAAAACAGCATGAAGAAATATACGAAAGCAGCATTTTTA
CAAAATGAAGGAACTGAAACACCTGTGTTTGTTCGTTTTTCAACGGTTATTCATGGTCAAGGTTCTCCTGAAACAGCACG
TGATCCACGCGGTTTCGCTGTTAAATTTTATACAGAAGAAGGAAATTACGATATTGTAGGTAACCATTTACCAGTCTTCT
TCATTCGTGATGCAATTAAATTCCCTGATATGGTGCATTCTTTAAAACCAGCACCTGATACAAATATTCAAACACCAGAT
CGTTACTGGGATTTCATGACGTTAAGTCCAGAATCTACACATATGATGACATGGGTATTTTCTGATTACGGTACACCAGC
AAGCTATCGTGAAATGGAAGGTTTCGGTGTACATTCATTCAAATGGATTAATGCAGAAGGTAAAATCGTCTACATTAAAT
ATCATTGGAAACCACAGCAAGGTGTACGTAACTTAAGTGCAAAAGAAGTGCAAGAAGTACAAGGAAAGGACTTCAACCAT
GCAACTCGTGACTTGTTCGATGCAATCGAAAAAGGAAATTACCCGAAATGGGATTTACACGTACAAGTAATGCAATTAGA
GGAAACAGATTCTTTAGATTTCGATCCGTTAGATCCGACGAAAGTTTGGCCAGAAGATCGTTTCCCATTAATGGAAGTAG
GGACAATGACGTTAAATCGTAACCCGAAAAACTTCTTCGCGGAAGTAGAACAAGTAGCGTTCTCTCCAAGTGCAACTGTA
AATGGTATTGAACCATCTGAAGATAAATTATTACAAGGTCGTTTATTCTCTTATCCAGATACACAGCGTTACCGCCTTGG
TGCAAACTACTTACAAATTCCTGTAAACTGCCCATACGCAGCTGTTCATAACCAACAACGTGATGGTGCGATGCAAATCA
ATCAAAACCCATCTACAATTAACTACGAACCGAGCCGTCATGCTGAAAATCCAGTTGAAGACCCAGCTTACCGCGATTCA
ACTATGAAAGTAGAAGGCTACGTATCTCGTGAAAAAATTGACAAACCAAATGATTTCAAACAAGCAGGTGAGCGTTACCG
TTCATTCTCTAAAGAAGAGCAAGACAACTTAATTGCAAACTTAACAAGTGACTTAAAAGACGTAAATGAACGTACGAAAT
TACTAGCTGTATGTAACTTCTTCCGTGCAGATCAAGAGTACGGTATGCGTTTAGCGCAAGCATTAAACGTTGATATTACG
CAATATGTAGGAAATGCTCCGAAATAA

Upstream 100 bases:

>100_bases
AAGAAATAGTTGACAAAGAACTAATTTTGAATAATAATTAATTTATAATAATTTTAAATAAATAATAATTACTACGAAAG
AAAGAGGAGGATCCCCCTAG

Downstream 100 bases:

>100_bases
ATAGGAAAAGACGACTGTTATGAAACGGTCGTCTTTTTTTAGTGTAAAGTTACAAGCGGGTATTCTTCATTTTCTTTATG
TCGGAATTTGGTGGTAAATC

Product: catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MNPNNRLTTNQGAPVGDNQNSRTAGRRGPVLLEDYHLVEKLAHFDRERIPERVVHARGAGAHGVFVTKNSMKKYTKAAFL
QNEGTETPVFVRFSTVIHGQGSPETARDPRGFAVKFYTEEGNYDIVGNHLPVFFIRDAIKFPDMVHSLKPAPDTNIQTPD
RYWDFMTLSPESTHMMTWVFSDYGTPASYREMEGFGVHSFKWINAEGKIVYIKYHWKPQQGVRNLSAKEVQEVQGKDFNH
ATRDLFDAIEKGNYPKWDLHVQVMQLEETDSLDFDPLDPTKVWPEDRFPLMEVGTMTLNRNPKNFFAEVEQVAFSPSATV
NGIEPSEDKLLQGRLFSYPDTQRYRLGANYLQIPVNCPYAAVHNQQRDGAMQINQNPSTINYEPSRHAENPVEDPAYRDS
TMKVEGYVSREKIDKPNDFKQAGERYRSFSKEEQDNLIANLTSDLKDVNERTKLLAVCNFFRADQEYGMRLAQALNVDIT
QYVGNAPK

Sequences:

>Translated_488_residues
MNPNNRLTTNQGAPVGDNQNSRTAGRRGPVLLEDYHLVEKLAHFDRERIPERVVHARGAGAHGVFVTKNSMKKYTKAAFL
QNEGTETPVFVRFSTVIHGQGSPETARDPRGFAVKFYTEEGNYDIVGNHLPVFFIRDAIKFPDMVHSLKPAPDTNIQTPD
RYWDFMTLSPESTHMMTWVFSDYGTPASYREMEGFGVHSFKWINAEGKIVYIKYHWKPQQGVRNLSAKEVQEVQGKDFNH
ATRDLFDAIEKGNYPKWDLHVQVMQLEETDSLDFDPLDPTKVWPEDRFPLMEVGTMTLNRNPKNFFAEVEQVAFSPSATV
NGIEPSEDKLLQGRLFSYPDTQRYRLGANYLQIPVNCPYAAVHNQQRDGAMQINQNPSTINYEPSRHAENPVEDPAYRDS
TMKVEGYVSREKIDKPNDFKQAGERYRSFSKEEQDNLIANLTSDLKDVNERTKLLAVCNFFRADQEYGMRLAQALNVDIT
QYVGNAPK
>Mature_488_residues
MNPNNRLTTNQGAPVGDNQNSRTAGRRGPVLLEDYHLVEKLAHFDRERIPERVVHARGAGAHGVFVTKNSMKKYTKAAFL
QNEGTETPVFVRFSTVIHGQGSPETARDPRGFAVKFYTEEGNYDIVGNHLPVFFIRDAIKFPDMVHSLKPAPDTNIQTPD
RYWDFMTLSPESTHMMTWVFSDYGTPASYREMEGFGVHSFKWINAEGKIVYIKYHWKPQQGVRNLSAKEVQEVQGKDFNH
ATRDLFDAIEKGNYPKWDLHVQVMQLEETDSLDFDPLDPTKVWPEDRFPLMEVGTMTLNRNPKNFFAEVEQVAFSPSATV
NGIEPSEDKLLQGRLFSYPDTQRYRLGANYLQIPVNCPYAAVHNQQRDGAMQINQNPSTINYEPSRHAENPVEDPAYRDS
TMKVEGYVSREKIDKPNDFKQAGERYRSFSKEEQDNLIANLTSDLKDVNERTKLLAVCNFFRADQEYGMRLAQALNVDIT
QYVGNAPK

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=485, Percent_Identity=47.8350515463918, Blast_Score=454, Evalue=1e-128,
Organism=Escherichia coli, GI48994891, Length=423, Percent_Identity=51.3002364066194, Blast_Score=415, Evalue=1e-117,
Organism=Caenorhabditis elegans, GI25147792, Length=471, Percent_Identity=46.9214437367304, Blast_Score=447, Evalue=1e-126,
Organism=Caenorhabditis elegans, GI25151141, Length=471, Percent_Identity=46.9214437367304, Blast_Score=446, Evalue=1e-125,
Organism=Caenorhabditis elegans, GI71998444, Length=478, Percent_Identity=44.7698744769874, Blast_Score=443, Evalue=1e-125,
Organism=Saccharomyces cerevisiae, GI6320462, Length=378, Percent_Identity=47.6190476190476, Blast_Score=363, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6321525, Length=368, Percent_Identity=47.2826086956522, Blast_Score=339, Evalue=7e-94,
Organism=Drosophila melanogaster, GI17981717, Length=477, Percent_Identity=46.5408805031447, Blast_Score=443, Evalue=1e-124,
Organism=Drosophila melanogaster, GI19920968, Length=477, Percent_Identity=44.2348008385744, Blast_Score=425, Evalue=1e-119,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 55833; Mature: 55833

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS00437 CATALASE_1 ; PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPNNRLTTNQGAPVGDNQNSRTAGRRGPVLLEDYHLVEKLAHFDRERIPERVVHARGAG
CCCCCCEECCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AHGVFVTKNSMKKYTKAAFLQNEGTETPVFVRFSTVIHGQGSPETARDPRGFAVKFYTEE
CCEEEEECHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCCCCCCCCEEEEEEEEC
GNYDIVGNHLPVFFIRDAIKFPDMVHSLKPAPDTNIQTPDRYWDFMTLSPESTHMMTWVF
CCEEEECCCCCEEEEHHHHHHHHHHHHCCCCCCCCCCCCHHHEEEEEECCCCCEEEEEEE
SDYGTPASYREMEGFGVHSFKWINAEGKIVYIKYHWKPQQGVRNLSAKEVQEVQGKDFNH
ECCCCCCCHHHHCCCCCCEEEEECCCCEEEEEEEECCHHHHHHCCCHHHHHHHCCCCCCH
ATRDLFDAIEKGNYPKWDLHVQVMQLEETDSLDFDPLDPTKVWPEDRFPLMEVGTMTLNR
HHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEECEEEECC
NPKNFFAEVEQVAFSPSATVNGIEPSEDKLLQGRLFSYPDTQRYRLGANYLQIPVNCPYA
CHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCCCCCCEEEECCCEEEEECCCCHH
AVHNQQRDGAMQINQNPSTINYEPSRHAENPVEDPAYRDSTMKVEGYVSREKIDKPNDFK
HHCCCCCCCCEEECCCCCEECCCCCCCCCCCCCCCCCCCCCEEEEEEECHHHCCCCHHHH
QAGERYRSFSKEEQDNLIANLTSDLKDVNERTKLLAVCNFFRADQEYGMRLAQALNVDIT
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHH
QYVGNAPK
HHCCCCCC
>Mature Secondary Structure
MNPNNRLTTNQGAPVGDNQNSRTAGRRGPVLLEDYHLVEKLAHFDRERIPERVVHARGAG
CCCCCCEECCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AHGVFVTKNSMKKYTKAAFLQNEGTETPVFVRFSTVIHGQGSPETARDPRGFAVKFYTEE
CCEEEEECHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCCCCCCCCEEEEEEEEC
GNYDIVGNHLPVFFIRDAIKFPDMVHSLKPAPDTNIQTPDRYWDFMTLSPESTHMMTWVF
CCEEEECCCCCEEEEHHHHHHHHHHHHCCCCCCCCCCCCHHHEEEEEECCCCCEEEEEEE
SDYGTPASYREMEGFGVHSFKWINAEGKIVYIKYHWKPQQGVRNLSAKEVQEVQGKDFNH
ECCCCCCCHHHHCCCCCCEEEEECCCCEEEEEEEECCHHHHHHCCCHHHHHHHCCCCCCH
ATRDLFDAIEKGNYPKWDLHVQVMQLEETDSLDFDPLDPTKVWPEDRFPLMEVGTMTLNR
HHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEECEEEECC
NPKNFFAEVEQVAFSPSATVNGIEPSEDKLLQGRLFSYPDTQRYRLGANYLQIPVNCPYA
CHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCCCCCCEEEECCCEEEEECCCCHH
AVHNQQRDGAMQINQNPSTINYEPSRHAENPVEDPAYRDSTMKVEGYVSREKIDKPNDFK
HHCCCCCCCCEEECCCCCEECCCCCCCCCCCCCCCCCCCCCEEEEEEECHHHCCCCHHHH
QAGERYRSFSKEEQDNLIANLTSDLKDVNERTKLLAVCNFFRADQEYGMRLAQALNVDIT
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHH
QYVGNAPK
HHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]