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The map label for this gene is yvrG [H]

Identifier: 49184059

GI number: 49184059

Start: 1092857

End: 1094599

Strand: Reverse

Name: yvrG [H]

Synonym: BAS1039

Alternate gene names: 49184059

Gene position: 1094599-1092857 (Counterclockwise)

Preceding gene: 49184060

Following gene: 49184055

Centisome position: 20.93

GC content: 33.96

Gene sequence:

>1743_bases
ATGAACTTTAATAAACGACTTATTATCCAGTTTATACTGCAACACGTATTTGTTTTAGTTACATTACTAATTGCTGTAGT
AGCTGCTTTCACTTATTTAATTTTTCTCGTTACTAGTACTTCATATGAACCGAACATTCCAGATGCTGATAATTTTATGA
TTGCAAGATACATCTCTTCAGAAGATGGCAATATTTCGTTAAAATCTGAAGTAAAAGACTTAATTAAAGAGAAAAATGAT
TGGATTCAAGTTGTCGAGGAAAACGGAAAAGTTCTCTATCACTTTAATACACCTAGTGACGTACCAACATCTTATACGAA
AGCATCTTTATTCTCGTATATACAAAATCATATAGAAAATCCTTATACATTTACATATTGGGAAATTGAATTAGAAGAAA
AGAACGTACTCGTTATTTACGGCGGCATGTTAAAAAGCAATGCATTACTGAAAACAATTCAGAAAGCGCACCCTTCTGTA
TCTACCGATTCGTTCACATTAACAGAAGAAGAACAACAGTTACTTTCTAAAGAAAAAGCAACACTTCAAATCTTTAATAG
TAAGGGCGATGAAGTATTCTCCTATCCAAACGGAAAGAAAAAAACGTTTTCTGTTATACAAGCTGCTCTTAATGAAAGGG
AACCGTGGAATCATAAAGAAAACACGTCTAGCTTTTACGACACAAATAGCAATCATCTCCTTGTTGTAACGGCAAAAAAT
GAGCACTACTACCCAGACGATGAAATAGACGATGTATTTACTAAAAAGTTTCTAATCGGATGCGGATTAATCCTTCTTAT
CGTATTTGTTTATTTAGTCATTCTTTCTATTTGGTACGGTAATAAATTTGGAAAACCGTTATTACATGCGATGCGCTGGC
TTAAAAATATTGCTGGTGGAAAGTACGAAGAGCCTGTTAGTAAAAAAGGGAAACCTATCAGGTTCAGGAAATCGGGTAAA
GAAAAATGGTCATTCCGCTTATTTAGTGATGTTACAAATTCACTAGAGCACCTTTCTATTACACTCAAAAAAAATGATGC
AATGAGGCAAGTACTGCAGCAAACACGTGAAGAATGGATTACTGGTCTAACGCACGATTTAAAAACACCACTAAGTTCTA
TATACGGCTACGCATTATTACTAGAATCAAAACAGTATAACTGGACTGATCGTGACATTCAGCAATTCGGCAGCGTTATG
AAAGAGAAATCTCAATATATGACCACACTAATTGATGACTTAAGCTTAACGTATCAATTAAAGAATAATAGTCTTCCTGC
GCAGCACGTAAACATTGAAATGAATCAATTCGTCCAAAAAGTATTATTACAATTCATTAATAATCCGACACTTCAAAATC
AAAATATTGAATTCGTACCAAGCTCAAACAAAATTCAATATTTCATTGAAGAAAAATGGTTCCAACGCATTATCGAAAAC
TTACTCGTAAACGCTGTAAAACATAATAATGAAACAACTAATGTCATTGTAAAGCTTTCACAAAATGCTACTTCATTCAC
ACTCTCTATTTCAGATAACGGAAAAGGAATGGATGATAAAACGAAAGAGCTTCTATTTGAGCGATATTACAGAGGAACAA
ATACAGAAGAAAGCAACATCGGAACTGGACTTGGCCTCGCTATTACAAAGCAACTCGTTCATGCTCATAACGGAGCGATT
TCTATTGATAGTGAACTAGGAAAAGGAACGACAATTATACTTGTGTTTCCGTTTTGTTCGTAG

Upstream 100 bases:

>100_bases
AAAACTGCGTGAAAAAATTGAACAAGACCCAAGTAAACCAGAATATATAAAAACCGTTCGCGGACTTGGCTATAAGTTCA
TTACAAAGTAGGGTGACGAT

Downstream 100 bases:

>100_bases
AAAAGGCGCTATGTGGCGTCTTTTCTTTTTGGGGAGAGTTCAGCGGTATATGAAATTATACGGATCGTTTTTTAAAGTGT
TTTATCGGTATATGAAATTA

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 580; Mature: 580

Protein sequence:

>580_residues
MNFNKRLIIQFILQHVFVLVTLLIAVVAAFTYLIFLVTSTSYEPNIPDADNFMIARYISSEDGNISLKSEVKDLIKEKND
WIQVVEENGKVLYHFNTPSDVPTSYTKASLFSYIQNHIENPYTFTYWEIELEEKNVLVIYGGMLKSNALLKTIQKAHPSV
STDSFTLTEEEQQLLSKEKATLQIFNSKGDEVFSYPNGKKKTFSVIQAALNEREPWNHKENTSSFYDTNSNHLLVVTAKN
EHYYPDDEIDDVFTKKFLIGCGLILLIVFVYLVILSIWYGNKFGKPLLHAMRWLKNIAGGKYEEPVSKKGKPIRFRKSGK
EKWSFRLFSDVTNSLEHLSITLKKNDAMRQVLQQTREEWITGLTHDLKTPLSSIYGYALLLESKQYNWTDRDIQQFGSVM
KEKSQYMTTLIDDLSLTYQLKNNSLPAQHVNIEMNQFVQKVLLQFINNPTLQNQNIEFVPSSNKIQYFIEEKWFQRIIEN
LLVNAVKHNNETTNVIVKLSQNATSFTLSISDNGKGMDDKTKELLFERYYRGTNTEESNIGTGLGLAITKQLVHAHNGAI
SIDSELGKGTTIILVFPFCS

Sequences:

>Translated_580_residues
MNFNKRLIIQFILQHVFVLVTLLIAVVAAFTYLIFLVTSTSYEPNIPDADNFMIARYISSEDGNISLKSEVKDLIKEKND
WIQVVEENGKVLYHFNTPSDVPTSYTKASLFSYIQNHIENPYTFTYWEIELEEKNVLVIYGGMLKSNALLKTIQKAHPSV
STDSFTLTEEEQQLLSKEKATLQIFNSKGDEVFSYPNGKKKTFSVIQAALNEREPWNHKENTSSFYDTNSNHLLVVTAKN
EHYYPDDEIDDVFTKKFLIGCGLILLIVFVYLVILSIWYGNKFGKPLLHAMRWLKNIAGGKYEEPVSKKGKPIRFRKSGK
EKWSFRLFSDVTNSLEHLSITLKKNDAMRQVLQQTREEWITGLTHDLKTPLSSIYGYALLLESKQYNWTDRDIQQFGSVM
KEKSQYMTTLIDDLSLTYQLKNNSLPAQHVNIEMNQFVQKVLLQFINNPTLQNQNIEFVPSSNKIQYFIEEKWFQRIIEN
LLVNAVKHNNETTNVIVKLSQNATSFTLSISDNGKGMDDKTKELLFERYYRGTNTEESNIGTGLGLAITKQLVHAHNGAI
SIDSELGKGTTIILVFPFCS
>Mature_580_residues
MNFNKRLIIQFILQHVFVLVTLLIAVVAAFTYLIFLVTSTSYEPNIPDADNFMIARYISSEDGNISLKSEVKDLIKEKND
WIQVVEENGKVLYHFNTPSDVPTSYTKASLFSYIQNHIENPYTFTYWEIELEEKNVLVIYGGMLKSNALLKTIQKAHPSV
STDSFTLTEEEQQLLSKEKATLQIFNSKGDEVFSYPNGKKKTFSVIQAALNEREPWNHKENTSSFYDTNSNHLLVVTAKN
EHYYPDDEIDDVFTKKFLIGCGLILLIVFVYLVILSIWYGNKFGKPLLHAMRWLKNIAGGKYEEPVSKKGKPIRFRKSGK
EKWSFRLFSDVTNSLEHLSITLKKNDAMRQVLQQTREEWITGLTHDLKTPLSSIYGYALLLESKQYNWTDRDIQQFGSVM
KEKSQYMTTLIDDLSLTYQLKNNSLPAQHVNIEMNQFVQKVLLQFINNPTLQNQNIEFVPSSNKIQYFIEEKWFQRIIEN
LLVNAVKHNNETTNVIVKLSQNATSFTLSISDNGKGMDDKTKELLFERYYRGTNTEESNIGTGLGLAITKQLVHAHNGAI
SIDSELGKGTTIILVFPFCS

Specific function: Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA, wapA- yxxG, dltABCDE, sunA, sunT-bdbA-yolJ-bdbB, sigO-rsoA, and sigX- rsiX), and negatively regulates the lytABC operon. Probably activates yv

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=228, Percent_Identity=28.0701754385965, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1786912, Length=248, Percent_Identity=25, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI145693157, Length=232, Percent_Identity=24.5689655172414, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1788393, Length=245, Percent_Identity=24.8979591836735, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1788713, Length=255, Percent_Identity=25.0980392156863, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1788549, Length=267, Percent_Identity=24.7191011235955, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1790436, Length=217, Percent_Identity=25.3456221198157, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1789808, Length=251, Percent_Identity=24.3027888446215, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI87082128, Length=229, Percent_Identity=20.5240174672489, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1786783, Length=330, Percent_Identity=19.6969696969697, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1789149, Length=252, Percent_Identity=23.4126984126984, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790346, Length=230, Percent_Identity=23.0434782608696, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788279, Length=308, Percent_Identity=22.4025974025974, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 66622; Mature: 66622

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFNKRLIIQFILQHVFVLVTLLIAVVAAFTYLIFLVTSTSYEPNIPDADNFMIARYISS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECC
EDGNISLKSEVKDLIKEKNDWIQVVEENGKVLYHFNTPSDVPTSYTKASLFSYIQNHIEN
CCCCEEEHHHHHHHHHCCCHHEEHEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCC
PYTFTYWEIELEEKNVLVIYGGMLKSNALLKTIQKAHPSVSTDSFTLTEEEQQLLSKEKA
CEEEEEEEEEECCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCEEECHHHHHHHHHCCC
TLQIFNSKGDEVFSYPNGKKKTFSVIQAALNEREPWNHKENTSSFYDTNSNHLLVVTAKN
EEEEECCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEECC
EHYYPDDEIDDVFTKKFLIGCGLILLIVFVYLVILSIWYGNKFGKPLLHAMRWLKNIAGG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
KYEEPVSKKGKPIRFRKSGKEKWSFRLFSDVTNSLEHLSITLKKNDAMRQVLQQTREEWI
CCCCCHHCCCCCEEEECCCCCHHHHHHHHHHHCCHHHEEEEEECCHHHHHHHHHHHHHHH
TGLTHDLKTPLSSIYGYALLLESKQYNWTDRDIQQFGSVMKEKSQYMTTLIDDLSLTYQL
HHHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEE
KNNSLPAQHVNIEMNQFVQKVLLQFINNPTLQNQNIEFVPSSNKIQYFIEEKWFQRIIEN
CCCCCCCCEECCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEHHHHHHHHHHHHH
LLVNAVKHNNETTNVIVKLSQNATSFTLSISDNGKGMDDKTKELLFERYYRGTNTEESNI
HHHHHHHCCCCCEEEEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCC
GTGLGLAITKQLVHAHNGAISIDSELGKGTTIILVFPFCS
CCCHHHHHHHHHHHHCCCCEEECCCCCCCCEEEEEECCCC
>Mature Secondary Structure
MNFNKRLIIQFILQHVFVLVTLLIAVVAAFTYLIFLVTSTSYEPNIPDADNFMIARYISS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECC
EDGNISLKSEVKDLIKEKNDWIQVVEENGKVLYHFNTPSDVPTSYTKASLFSYIQNHIEN
CCCCEEEHHHHHHHHHCCCHHEEHEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCC
PYTFTYWEIELEEKNVLVIYGGMLKSNALLKTIQKAHPSVSTDSFTLTEEEQQLLSKEKA
CEEEEEEEEEECCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCEEECHHHHHHHHHCCC
TLQIFNSKGDEVFSYPNGKKKTFSVIQAALNEREPWNHKENTSSFYDTNSNHLLVVTAKN
EEEEECCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEECC
EHYYPDDEIDDVFTKKFLIGCGLILLIVFVYLVILSIWYGNKFGKPLLHAMRWLKNIAGG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
KYEEPVSKKGKPIRFRKSGKEKWSFRLFSDVTNSLEHLSITLKKNDAMRQVLQQTREEWI
CCCCCHHCCCCCEEEECCCCCHHHHHHHHHHHCCHHHEEEEEECCHHHHHHHHHHHHHHH
TGLTHDLKTPLSSIYGYALLLESKQYNWTDRDIQQFGSVMKEKSQYMTTLIDDLSLTYQL
HHHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEE
KNNSLPAQHVNIEMNQFVQKVLLQFINNPTLQNQNIEFVPSSNKIQYFIEEKWFQRIIEN
CCCCCCCCEECCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEHHHHHHHHHHHHH
LLVNAVKHNNETTNVIVKLSQNATSFTLSISDNGKGMDDKTKELLFERYYRGTNTEESNI
HHHHHHHCCCCCEEEEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCC
GTGLGLAITKQLVHAHNGAISIDSELGKGTTIILVFPFCS
CCCHHHHHHHHHHHHCCCCEEECCCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]