| Definition | Bacillus anthracis str. Sterne chromosome, complete genome. |
|---|---|
| Accession | NC_005945 |
| Length | 5,228,663 |
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The map label for this gene is helD [H]
Identifier: 49183994
GI number: 49183994
Start: 1027423
End: 1029753
Strand: Reverse
Name: helD [H]
Synonym: BAS0973
Alternate gene names: 49183994
Gene position: 1029753-1027423 (Counterclockwise)
Preceding gene: 49183995
Following gene: 49183993
Centisome position: 19.69
GC content: 39.85
Gene sequence:
>2331_bases ATGAACAAAAAACTTGATCAAGAGCAAAAACGATTGGATACCGTAATCGAAACGATTACGCAGCAAATTGATAAGCTGGA AAACGAAACTGGCAGACGCCGAGCAGAAGTAATCAATATTCGTAAACATTTCTGGGATGACGTGAAAGTGAATACTGATA CTTTTGATGATTATCTTGAAACAGTTATCAACTTAAGACAACAAGCTCAGTCACTAGCTGTCACACAAATTACTCATAAG CACACCTTTAATCGACTTGCCGCATTAAGACGCATGCATAAAGCACCTTATTTTGGACGAATTGATTTCAAAGAAGAAGG AGAATCTGCTGCGGAGCAAATTTATATTGGCGTTGCTACACTTACTGATGCTAGCGGAGAAAACTTTCTTATATACGACT GGCGCGCACCCATTTCGAGTGTCTACTACGATTATCCACCAGGGCCGGCTGAATATAGTACACCAGGCGGAGTAATCCAC GGTAATGTGGAGAAAAAATTACAATACATTATTCAAAATGGCGAGATTGATTCTATGTTCGATACGAGCCTTACAATTGG CGATGAGATCTTGCAACAAGCGCTCGGAAAAGGTACAAACAAACATATGCAAAGTATCGTTGCTACGATTCAGCGCGAGC AAAATGAAATTATTCGTCACGATGAAGGCCGACTCCTTATCGTACAAGGAGCTGCTGGTAGCGGTAAAACGTCAGCCGCC CTGCAACGAATCGCCTACTTACTATATAAATATCGCGAATGGCTAAAAGCTGATCAAATTATTCTCTTCTCCCCTAACTC TATGTTCAACAGCTACGTTTCTAACGTACTACCTGAACTTGGTGAAGAGAATATGCAGCAAGTTACATTCCAAGAATATT TAAACCATAGACTAAGTAAGTCATTTGATGTGGAAGACCCTTATGAACAATTAGAGTATATGCTAACTGAAACGAATAGC CCTGCCTATAAAACGAGAAATGCTAGTATTCGTTTTAAAGCATCTACTCAATTTTTCGAGATGATTCGAGCGTACAGACA ATCTCTTGAATCTTCAGGCATGCTATTTAGAGGAATGAAATTTAGAGGAAAACTGATTGTTTCTGCGAAAGAAATTACAG AGCAGTTTTACAATACCGACTCCTCCCTCCGCTTCCATAGTCGAATTGAGAAGTTAACGGATTGGCTAAATAAACAAATA GATGCAATTGAAAAAGCAGAATTGAAAAAGCCTTGGGTAGAAGAAGAAATTGAATTACTTAGTAAAGATGAATACCAAAA GGCTTATAAATACTTGCAGAAAAAAGGCGAGTTTGACGACAACTCCTTTCAAGATTTTGAGAAAGAAACGAGAGTACTTG GACGTATGATTGTCCGTAAAAAATTGAAGCCGCTGCGTAAAGGCGTTCAAACATTACGCTTTATCAATTTCACAGGTATA TATAAACAACTTTTCACAGATGCATCATGGGGGACTGGAGAAAAACTGAAAGAATGGGATGACATTTGCTCACTAACGGT GAACATGCTCGATGAAGGAAAGCTATATTACGAGGATGCGACTCCATTTTTACTTTTAAAAGAGTTAATTGAAGGTTTCC AAACGAACAGATCGATTAAACACGTACTCGTAGACGAAGCACAAGATTATTCGCCGTTTCAGTTCGAGTTTTTAAAACGT CTCTTCCCTGCCGCAAGAATGACGGTACTTGGAGACTTTAACCAAGCAATATTTGCTCATGCGAGTGAAACAGTTAATTT CGATACACTTACGAATTTATACGGGCCAGACGAAACAAACGGCATTAACTTAACTCGTAGTTATCGCTCAACAAAACCAA TTATTGAATTTACACGTGCTCTCGTACCGGAAGGGAAGAACATTCACGCCTTTGAACGTGACGGTGAGAAACCTACAGTG ACGAAAGTAGCGAATGAGAGCGAACTGCACGAACGTATTACTGCCAAAGTTGCTGAATTACAAAAACAAAATCACAACAC GATCGCAATTATATGTAAATCTGCAGCTGAAAGCGCCGCTGCCTATGAGGCACTTAGTCCTATCGAGAATATTAAACTCG TGAAGAGTAACTCAGCCGAGTATGAGCAAGGCATTGTCGTGATCCCAGCTTACTTAGCGAAGGGTATCGAATTTGATGCC GTTATTATTTACGATGCGTCTAAAGATGTATACAACGATGAGAGCGTTCGTCGATTGTTCTACACTGCTTGTACACGCGC AATGCATGAATTACAACTTTATAGCGTTGGCGAGGTTAGTCCTTTTATTGTTGAGGCTGATTCGGAGAGTTTTGAGCTTA TTACACCTTGA
Upstream 100 bases:
>100_bases TTTCTAAAATTAAAAGAACGTATTTATCCCTATCTTAATTGTACACCAAAACACATCTTCAGTCAACCTCTATTTTTCAC TTTTAAAGGAGTGCTATCGT
Downstream 100 bases:
>100_bases TAACAATCAAGGTGTTTCTTTTTTGTGCAGGATTTACAACTTTAAAGTAGAATATATCAGTTTAGAAAAAAGTTAAGGAG CGAAAAGATGAACCATTATT
Product: UvrD/Rep family helicase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 776; Mature: 776
Protein sequence:
>776_residues MNKKLDQEQKRLDTVIETITQQIDKLENETGRRRAEVINIRKHFWDDVKVNTDTFDDYLETVINLRQQAQSLAVTQITHK HTFNRLAALRRMHKAPYFGRIDFKEEGESAAEQIYIGVATLTDASGENFLIYDWRAPISSVYYDYPPGPAEYSTPGGVIH GNVEKKLQYIIQNGEIDSMFDTSLTIGDEILQQALGKGTNKHMQSIVATIQREQNEIIRHDEGRLLIVQGAAGSGKTSAA LQRIAYLLYKYREWLKADQIILFSPNSMFNSYVSNVLPELGEENMQQVTFQEYLNHRLSKSFDVEDPYEQLEYMLTETNS PAYKTRNASIRFKASTQFFEMIRAYRQSLESSGMLFRGMKFRGKLIVSAKEITEQFYNTDSSLRFHSRIEKLTDWLNKQI DAIEKAELKKPWVEEEIELLSKDEYQKAYKYLQKKGEFDDNSFQDFEKETRVLGRMIVRKKLKPLRKGVQTLRFINFTGI YKQLFTDASWGTGEKLKEWDDICSLTVNMLDEGKLYYEDATPFLLLKELIEGFQTNRSIKHVLVDEAQDYSPFQFEFLKR LFPAARMTVLGDFNQAIFAHASETVNFDTLTNLYGPDETNGINLTRSYRSTKPIIEFTRALVPEGKNIHAFERDGEKPTV TKVANESELHERITAKVAELQKQNHNTIAIICKSAAESAAAYEALSPIENIKLVKSNSAEYEQGIVVIPAYLAKGIEFDA VIIYDASKDVYNDESVRRLFYTACTRAMHELQLYSVGEVSPFIVEADSESFELITP
Sequences:
>Translated_776_residues MNKKLDQEQKRLDTVIETITQQIDKLENETGRRRAEVINIRKHFWDDVKVNTDTFDDYLETVINLRQQAQSLAVTQITHK HTFNRLAALRRMHKAPYFGRIDFKEEGESAAEQIYIGVATLTDASGENFLIYDWRAPISSVYYDYPPGPAEYSTPGGVIH GNVEKKLQYIIQNGEIDSMFDTSLTIGDEILQQALGKGTNKHMQSIVATIQREQNEIIRHDEGRLLIVQGAAGSGKTSAA LQRIAYLLYKYREWLKADQIILFSPNSMFNSYVSNVLPELGEENMQQVTFQEYLNHRLSKSFDVEDPYEQLEYMLTETNS PAYKTRNASIRFKASTQFFEMIRAYRQSLESSGMLFRGMKFRGKLIVSAKEITEQFYNTDSSLRFHSRIEKLTDWLNKQI DAIEKAELKKPWVEEEIELLSKDEYQKAYKYLQKKGEFDDNSFQDFEKETRVLGRMIVRKKLKPLRKGVQTLRFINFTGI YKQLFTDASWGTGEKLKEWDDICSLTVNMLDEGKLYYEDATPFLLLKELIEGFQTNRSIKHVLVDEAQDYSPFQFEFLKR LFPAARMTVLGDFNQAIFAHASETVNFDTLTNLYGPDETNGINLTRSYRSTKPIIEFTRALVPEGKNIHAFERDGEKPTV TKVANESELHERITAKVAELQKQNHNTIAIICKSAAESAAAYEALSPIENIKLVKSNSAEYEQGIVVIPAYLAKGIEFDA VIIYDASKDVYNDESVRRLFYTACTRAMHELQLYSVGEVSPFIVEADSESFELITP >Mature_776_residues MNKKLDQEQKRLDTVIETITQQIDKLENETGRRRAEVINIRKHFWDDVKVNTDTFDDYLETVINLRQQAQSLAVTQITHK HTFNRLAALRRMHKAPYFGRIDFKEEGESAAEQIYIGVATLTDASGENFLIYDWRAPISSVYYDYPPGPAEYSTPGGVIH GNVEKKLQYIIQNGEIDSMFDTSLTIGDEILQQALGKGTNKHMQSIVATIQREQNEIIRHDEGRLLIVQGAAGSGKTSAA LQRIAYLLYKYREWLKADQIILFSPNSMFNSYVSNVLPELGEENMQQVTFQEYLNHRLSKSFDVEDPYEQLEYMLTETNS PAYKTRNASIRFKASTQFFEMIRAYRQSLESSGMLFRGMKFRGKLIVSAKEITEQFYNTDSSLRFHSRIEKLTDWLNKQI DAIEKAELKKPWVEEEIELLSKDEYQKAYKYLQKKGEFDDNSFQDFEKETRVLGRMIVRKKLKPLRKGVQTLRFINFTGI YKQLFTDASWGTGEKLKEWDDICSLTVNMLDEGKLYYEDATPFLLLKELIEGFQTNRSIKHVLVDEAQDYSPFQFEFLKR LFPAARMTVLGDFNQAIFAHASETVNFDTLTNLYGPDETNGINLTRSYRSTKPIIEFTRALVPEGKNIHAFERDGEKPTV TKVANESELHERITAKVAELQKQNHNTIAIICKSAAESAAAYEALSPIENIKLVKSNSAEYEQGIVVIPAYLAKGIEFDA VIIYDASKDVYNDESVRRLFYTACTRAMHELQLYSVGEVSPFIVEADSESFELITP
Specific function: Catalyzes the unwinding of duplex DNA in the 3' to 5' direction; this reaction is dependent on the hydrolysis of ATP [H]
COG id: COG3973
COG function: function code R; Superfamily I DNA and RNA helicases
Gene ontology:
Cell location: Cytoplasm (Probable) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 uvrD-like helicase ATP-binding domain [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR000212 - InterPro: IPR014016 [H]
Pfam domain/function: PF00580 UvrD-helicase [H]
EC number: =3.6.4.12 [H]
Molecular weight: Translated: 89263; Mature: 89263
Theoretical pI: Translated: 5.45; Mature: 5.45
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 1.8 %Met (Translated Protein) 2.2 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 1.8 %Met (Mature Protein) 2.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNKKLDQEQKRLDTVIETITQQIDKLENETGRRRAEVINIRKHFWDDVKVNTDTFDDYLE CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHH TVINLRQQAQSLAVTQITHKHTFNRLAALRRMHKAPYFGRIDFKEEGESAAEQIYIGVAT HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCHHHHHHEEEEEEE LTDASGENFLIYDWRAPISSVYYDYPPGPAEYSTPGGVIHGNVEKKLQYIIQNGEIDSMF EECCCCCEEEEEECCCCHHHCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHCCCCCCHH DTSLTIGDEILQQALGKGTNKHMQSIVATIQREQNEIIRHDEGRLLIVQGAAGSGKTSAA CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHH LQRIAYLLYKYREWLKADQIILFSPNSMFNSYVSNVLPELGEENMQQVTFQEYLNHRLSK HHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC SFDVEDPYEQLEYMLTETNSPAYKTRNASIRFKASTQFFEMIRAYRQSLESSGMLFRGMK CCCCCCHHHHHHHHHHCCCCCCEECCCCEEEEECHHHHHHHHHHHHHHHHHCCCEEECCC FRGKLIVSAKEITEQFYNTDSSLRFHSRIEKLTDWLNKQIDAIEKAELKKPWVEEEIELL CCCEEEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH SKDEYQKAYKYLQKKGEFDDNSFQDFEKETRVLGRMIVRKKLKPLRKGVQTLRFINFTGI CCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH YKQLFTDASWGTGEKLKEWDDICSLTVNMLDEGKLYYEDATPFLLLKELIEGFQTNRSIK HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCCHH HVLVDEAQDYSPFQFEFLKRLFPAARMTVLGDFNQAIFAHASETVNFDTLTNLYGPDETN HHHHHCCCCCCCHHHHHHHHHCCHHHHHHHCCHHHHHHHHCCCCCCHHHHHHCCCCCCCC GINLTRSYRSTKPIIEFTRALVPEGKNIHAFERDGEKPTVTKVANESELHERITAKVAEL CCEEEECCCCCCHHHHHHHHHCCCCCCEECCCCCCCCCCHHHHCCHHHHHHHHHHHHHHH QKQNHNTIAIICKSAAESAAAYEALSPIENIKLVKSNSAEYEQGIVVIPAYLAKGIEFDA HHCCCCEEEEEEECHHHHHHHHHHHCCHHHEEEEECCCCHHHCCEEEEEHHHHCCCCCCE VIIYDASKDVYNDESVRRLFYTACTRAMHELQLYSVGEVSPFIVEADSESFELITP EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCEECCC >Mature Secondary Structure MNKKLDQEQKRLDTVIETITQQIDKLENETGRRRAEVINIRKHFWDDVKVNTDTFDDYLE CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHH TVINLRQQAQSLAVTQITHKHTFNRLAALRRMHKAPYFGRIDFKEEGESAAEQIYIGVAT HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCHHHHHHEEEEEEE LTDASGENFLIYDWRAPISSVYYDYPPGPAEYSTPGGVIHGNVEKKLQYIIQNGEIDSMF EECCCCCEEEEEECCCCHHHCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHCCCCCCHH DTSLTIGDEILQQALGKGTNKHMQSIVATIQREQNEIIRHDEGRLLIVQGAAGSGKTSAA CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHH LQRIAYLLYKYREWLKADQIILFSPNSMFNSYVSNVLPELGEENMQQVTFQEYLNHRLSK HHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC SFDVEDPYEQLEYMLTETNSPAYKTRNASIRFKASTQFFEMIRAYRQSLESSGMLFRGMK CCCCCCHHHHHHHHHHCCCCCCEECCCCEEEEECHHHHHHHHHHHHHHHHHCCCEEECCC FRGKLIVSAKEITEQFYNTDSSLRFHSRIEKLTDWLNKQIDAIEKAELKKPWVEEEIELL CCCEEEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH SKDEYQKAYKYLQKKGEFDDNSFQDFEKETRVLGRMIVRKKLKPLRKGVQTLRFINFTGI CCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH YKQLFTDASWGTGEKLKEWDDICSLTVNMLDEGKLYYEDATPFLLLKELIEGFQTNRSIK HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCCHH HVLVDEAQDYSPFQFEFLKRLFPAARMTVLGDFNQAIFAHASETVNFDTLTNLYGPDETN HHHHHCCCCCCCHHHHHHHHHCCHHHHHHHCCHHHHHHHHCCCCCCHHHHHHCCCCCCCC GINLTRSYRSTKPIIEFTRALVPEGKNIHAFERDGEKPTVTKVANESELHERITAKVAEL CCEEEECCCCCCHHHHHHHHHCCCCCCEECCCCCCCCCCHHHHCCHHHHHHHHHHHHHHH QKQNHNTIAIICKSAAESAAAYEALSPIENIKLVKSNSAEYEQGIVVIPAYLAKGIEFDA HHCCCCEEEEEEECHHHHHHHHHHHCCHHHEEEEECCCCHHHCCEEEEEHHHHCCCCCCE VIIYDASKDVYNDESVRRLFYTACTRAMHELQLYSVGEVSPFIVEADSESFELITP EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCEECCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9384377 [H]