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The map label for this gene is yusP [H]

Identifier: 49183655

GI number: 49183655

Start: 680384

End: 681814

Strand: Direct

Name: yusP [H]

Synonym: BAS0630

Alternate gene names: 49183655

Gene position: 680384-681814 (Clockwise)

Preceding gene: 49183654

Following gene: 49183656

Centisome position: 13.01

GC content: 37.88

Gene sequence:

>1431_bases
ATGGAGCAACAAGAAAATATAAACAGAAAGTTGTTGTTAATCGGTTTAATCATTGCCATGCTATTTGCTGCATTAGATGG
AACAATCGTTGGTACAGCAATGCCGCGTATCGTCGGTGAACTAGGCGGATTAAGCTTAATGACGTGGTTAACAACAGCCT
ATATGTTAACATCAACGACAGTTGTACCAATTGCAGGTAAATTAGCGGATTTACTTGGCCGTCGTAACGTATATATAACA
GGGCTAGTTATCTTTATGGTTGGCTCAGCGTTATGTGGTATGGCAAATGGCATGACAGAATTAATTATTTTCCGTGGTAT
TCAAGGTCTTGGTGGCGGTATTATGATGCCGATGGCTATGATTATTATCGGAGATATGTTCACGGGGAAAGAACGTGCGA
AATGGCAAGGTATTTTTGGTGCGTTATACGGTCTTGCTTCTGTAATTGGGCCACAAGTTGGTGGCTGGATTGTAGACGCA
GTAAACTGGAGATGGGTATTCTACATTAACTTACCAGTGGGTATTTTAGCAACAATCTTTATTGCAATGGGATTAAAATC
ACATAAACAAACAGGACCAATTAAAATTGATATCGCTGGAATCTTCACGATGATTCTCGGTGTTGTCAGTTTATTACTTG
CATTAACGTTTGGCGGAAAAGATTACGCATGGGATTCTTGGCAAATTATCGGGTTATTTGCATTAGCTCTAATTGGTATT
GTTAGCTTTGTTATCGTTGAAACGAAAGCAGAAGAACCAATTTTACCGATGCATTTCTTTAAAAATCGTACATTTACATT
ACTAAATGCGATTGGATTCTTTATGAGTATCGGAATGTTCGGTGCGATTATGTTCGTCCCATTCTTCATGCAAGGAATTG
TAGGAGTAAGTGCTGCTGAATCAGGTACAATTATGACGCCAATGATGATTACTATGATTGTGATGAGTATTATCGGCGGG
CAACTTGTATTAAAAGTTGGTGTAAAACCACAAATTATTACAGGAATGCTTATAATGGCTGGAGGATTCTGGTTATTAAC
AACGATGGATATGCACACAACTAAATTGACTGCTACTTCTTATATGATGGTTATCGGTTTAGGAATGGGTCTTGTAATGC
CGACATTAACGTTAGCGTTACAAGAAAGCTTCCCGAAAAAAGATCTTGGTGTCGTAACATCATCAAGTCAGTTCTTCCGT
CAAATCGGTGGAACATTTGGTATTACAATTTTAGGATCAATTATGAATAACACTTCAGGTACAACATTAACAAAAAATTT
AGTACCTGTATTAGATACGTTCCCGAAAGAAGCGGGACAAATGGTAACGAAATTTAAAGATATGATTCATACGGACCCAC
AAGGTTTATATTCAATGCTATTTAGCCCAGAGGCATTAAAACAAATGCCAGAAGCATTGTACCAATTTTGA

Upstream 100 bases:

>100_bases
GAAAGAGAAGATTTGTTACGCCTCTTTGAGAAGCTCGAAACAATTATTTGCGGGACACAAGAGAAAAAAGAGAATAACTA
AGAGGAATTGAGGAGATTAC

Downstream 100 bases:

>100_bases
AAAACTCTTTAGTAGACTCTCTTCATACTGTATTCTTAACAGGATTAGTATTCATTGTAGTGGGTGCTATCTTTACGATT
TTCTTACAGAAGATTAAACT

Product: multidrug-efflux transporter

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MEQQENINRKLLLIGLIIAMLFAALDGTIVGTAMPRIVGELGGLSLMTWLTTAYMLTSTTVVPIAGKLADLLGRRNVYIT
GLVIFMVGSALCGMANGMTELIIFRGIQGLGGGIMMPMAMIIIGDMFTGKERAKWQGIFGALYGLASVIGPQVGGWIVDA
VNWRWVFYINLPVGILATIFIAMGLKSHKQTGPIKIDIAGIFTMILGVVSLLLALTFGGKDYAWDSWQIIGLFALALIGI
VSFVIVETKAEEPILPMHFFKNRTFTLLNAIGFFMSIGMFGAIMFVPFFMQGIVGVSAAESGTIMTPMMITMIVMSIIGG
QLVLKVGVKPQIITGMLIMAGGFWLLTTMDMHTTKLTATSYMMVIGLGMGLVMPTLTLALQESFPKKDLGVVTSSSQFFR
QIGGTFGITILGSIMNNTSGTTLTKNLVPVLDTFPKEAGQMVTKFKDMIHTDPQGLYSMLFSPEALKQMPEALYQF

Sequences:

>Translated_476_residues
MEQQENINRKLLLIGLIIAMLFAALDGTIVGTAMPRIVGELGGLSLMTWLTTAYMLTSTTVVPIAGKLADLLGRRNVYIT
GLVIFMVGSALCGMANGMTELIIFRGIQGLGGGIMMPMAMIIIGDMFTGKERAKWQGIFGALYGLASVIGPQVGGWIVDA
VNWRWVFYINLPVGILATIFIAMGLKSHKQTGPIKIDIAGIFTMILGVVSLLLALTFGGKDYAWDSWQIIGLFALALIGI
VSFVIVETKAEEPILPMHFFKNRTFTLLNAIGFFMSIGMFGAIMFVPFFMQGIVGVSAAESGTIMTPMMITMIVMSIIGG
QLVLKVGVKPQIITGMLIMAGGFWLLTTMDMHTTKLTATSYMMVIGLGMGLVMPTLTLALQESFPKKDLGVVTSSSQFFR
QIGGTFGITILGSIMNNTSGTTLTKNLVPVLDTFPKEAGQMVTKFKDMIHTDPQGLYSMLFSPEALKQMPEALYQF
>Mature_476_residues
MEQQENINRKLLLIGLIIAMLFAALDGTIVGTAMPRIVGELGGLSLMTWLTTAYMLTSTTVVPIAGKLADLLGRRNVYIT
GLVIFMVGSALCGMANGMTELIIFRGIQGLGGGIMMPMAMIIIGDMFTGKERAKWQGIFGALYGLASVIGPQVGGWIVDA
VNWRWVFYINLPVGILATIFIAMGLKSHKQTGPIKIDIAGIFTMILGVVSLLLALTFGGKDYAWDSWQIIGLFALALIGI
VSFVIVETKAEEPILPMHFFKNRTFTLLNAIGFFMSIGMFGAIMFVPFFMQGIVGVSAAESGTIMTPMMITMIVMSIIGG
QLVLKVGVKPQIITGMLIMAGGFWLLTTMDMHTTKLTATSYMMVIGLGMGLVMPTLTLALQESFPKKDLGVVTSSSQFFR
QIGGTFGITILGSIMNNTSGTTLTKNLVPVLDTFPKEAGQMVTKFKDMIHTDPQGLYSMLFSPEALKQMPEALYQF

Specific function: Translocase That Confers Resistance To Substances Of High Hydrophobicity. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI1789042, Length=462, Percent_Identity=25.7575757575758, Blast_Score=155, Evalue=5e-39,
Organism=Escherichia coli, GI1788710, Length=405, Percent_Identity=27.6543209876543, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI87081983, Length=413, Percent_Identity=24.6973365617433, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1790195, Length=329, Percent_Identity=29.1793313069909, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1788392, Length=397, Percent_Identity=29.2191435768262, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1790146, Length=190, Percent_Identity=26.3157894736842, Blast_Score=69, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6322958, Length=490, Percent_Identity=27.5510204081633, Blast_Score=147, Evalue=4e-36,
Organism=Saccharomyces cerevisiae, GI6323735, Length=347, Percent_Identity=28.8184438040346, Blast_Score=129, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6319770, Length=406, Percent_Identity=25.3694581280788, Blast_Score=124, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6319783, Length=403, Percent_Identity=26.5508684863524, Blast_Score=106, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6321663, Length=470, Percent_Identity=24.6808510638298, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6325455, Length=231, Percent_Identity=27.7056277056277, Blast_Score=93, Evalue=9e-20,
Organism=Saccharomyces cerevisiae, GI6324954, Length=373, Percent_Identity=24.6648793565684, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6323520, Length=365, Percent_Identity=26.027397260274, Blast_Score=74, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 51496; Mature: 51496

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
8.0 %Met     (Translated Protein)
8.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
8.0 %Met     (Mature Protein)
8.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQQENINRKLLLIGLIIAMLFAALDGTIVGTAMPRIVGELGGLSLMTWLTTAYMLTSTT
CCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
VVPIAGKLADLLGRRNVYITGLVIFMVGSALCGMANGMTELIIFRGIQGLGGGIMMPMAM
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHH
IIIGDMFTGKERAKWQGIFGALYGLASVIGPQVGGWIVDAVNWRWVFYINLPVGILATIF
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCEEEEEEEECCHHHHHHHH
IAMGLKSHKQTGPIKIDIAGIFTMILGVVSLLLALTFGGKDYAWDSWQIIGLFALALIGI
HHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
VSFVIVETKAEEPILPMHFFKNRTFTLLNAIGFFMSIGMFGAIMFVPFFMQGIVGVSAAE
HHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SGTIMTPMMITMIVMSIIGGQLVLKVGVKPQIITGMLIMAGGFWLLTTMDMHTTKLTATS
CCCCHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCHHEEEECCHHHHHHHHHH
YMMVIGLGMGLVMPTLTLALQESFPKKDLGVVTSSSQFFRQIGGTFGITILGSIMNNTSG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHCCCHHHHHHHHHHCCCCC
TTLTKNLVPVLDTFPKEAGQMVTKFKDMIHTDPQGLYSMLFSPEALKQMPEALYQF
CEEHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MEQQENINRKLLLIGLIIAMLFAALDGTIVGTAMPRIVGELGGLSLMTWLTTAYMLTSTT
CCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
VVPIAGKLADLLGRRNVYITGLVIFMVGSALCGMANGMTELIIFRGIQGLGGGIMMPMAM
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHH
IIIGDMFTGKERAKWQGIFGALYGLASVIGPQVGGWIVDAVNWRWVFYINLPVGILATIF
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCEEEEEEEECCHHHHHHHH
IAMGLKSHKQTGPIKIDIAGIFTMILGVVSLLLALTFGGKDYAWDSWQIIGLFALALIGI
HHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
VSFVIVETKAEEPILPMHFFKNRTFTLLNAIGFFMSIGMFGAIMFVPFFMQGIVGVSAAE
HHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SGTIMTPMMITMIVMSIIGGQLVLKVGVKPQIITGMLIMAGGFWLLTTMDMHTTKLTATS
CCCCHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCHHEEEECCHHHHHHHHHH
YMMVIGLGMGLVMPTLTLALQESFPKKDLGVVTSSSQFFRQIGGTFGITILGSIMNNTSG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHCCCHHHHHHHHHHCCCCC
TTLTKNLVPVLDTFPKEAGQMVTKFKDMIHTDPQGLYSMLFSPEALKQMPEALYQF
CEEHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]