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The map label for this gene is acpS

Identifier: 46447345

GI number: 46447345

Start: 2050094

End: 2050462

Strand: Direct

Name: acpS

Synonym: pc1711

Alternate gene names: 46447345

Gene position: 2050094-2050462 (Clockwise)

Preceding gene: 46447344

Following gene: 46447348

Centisome position: 84.91

GC content: 37.4

Gene sequence:

>369_bases
ATGACTTTAGGAATTGGCAACGATATTATTGAGATTGAGCGAATACAAGCAAATATTAAAAAGTATGGACAACGCTTTTT
AAATCGAGTTTTTACCAAAAATGAACAAATATATTGTTTAAATCGTAAAATGCCCGCTCTACATCTTGCCGGTCGATTTG
CCGCTAAAGAAGCGGTGGTCAAAGCTTTGGGGACAGGTTTTAGCCAAGGTATTTCTTGGCTAGACGTCGAAATCCTCAAT
GATGCAAATGGAAAACCTTACGTTTCTATTTCTCCTCTTTTAACTCAGTTATTTGCTTCCCCTAAACTTCTTATCTCGAT
TAGTCACTGCCATCATTACGCAACAGCATTTGCTGTTTGGTCTTCTTAA

Upstream 100 bases:

>100_bases
AGCTTCTAAAAATAGTAACCTTTTTTTATTTAAGTTGATCTCTTCATACGTCAAATGAAACGCTGGTTTTATCAAACAAA
AACCTTACCCCATTGTTAAC

Downstream 100 bases:

>100_bases
TTGATCCCGAATTTCATTCTTCGGGTCTTTTTATTTATCTGAAAAAGACAAAATTACACGTAAAGGGTTTACAATCCAAA
AGGGTAAAAGAACGTCAATT

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 122; Mature: 121

Protein sequence:

>122_residues
MTLGIGNDIIEIERIQANIKKYGQRFLNRVFTKNEQIYCLNRKMPALHLAGRFAAKEAVVKALGTGFSQGISWLDVEILN
DANGKPYVSISPLLTQLFASPKLLISISHCHHYATAFAVWSS

Sequences:

>Translated_122_residues
MTLGIGNDIIEIERIQANIKKYGQRFLNRVFTKNEQIYCLNRKMPALHLAGRFAAKEAVVKALGTGFSQGISWLDVEILN
DANGKPYVSISPLLTQLFASPKLLISISHCHHYATAFAVWSS
>Mature_121_residues
TLGIGNDIIEIERIQANIKKYGQRFLNRVFTKNEQIYCLNRKMPALHLAGRFAAKEAVVKALGTGFSQGISWLDVEILND
ANGKPYVSISPLLTQLFASPKLLISISHCHHYATAFAVWSS

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=123, Percent_Identity=35.7723577235772, Blast_Score=80, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_PARUW (Q6MAG4)

Other databases:

- EMBL:   BX908798
- RefSeq:   YP_008710.1
- ProteinModelPortal:   Q6MAG4
- SMR:   Q6MAG4
- STRING:   Q6MAG4
- GeneID:   2781017
- GenomeReviews:   BX908798_GR
- KEGG:   pcu:pc1711
- NMPDR:   fig|264201.1.peg.1711
- eggNOG:   COG0736
- HOGENOM:   HBG734479
- OMA:   NSSAIAY
- PhylomeDB:   Q6MAG4
- ProtClustDB:   PRK00070
- BioCyc:   CPRO264201:PC1711-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 13591; Mature: 13460

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLGIGNDIIEIERIQANIKKYGQRFLNRVFTKNEQIYCLNRKMPALHLAGRFAAKEAVV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHH
KALGTGFSQGISWLDVEILNDANGKPYVSISPLLTQLFASPKLLISISHCHHYATAFAVW
HHHCCCHHHCCCEEEEEEEECCCCCCEEEHHHHHHHHHCCCEEEEEHHHHHHHHHHHEEE
SS
CC
>Mature Secondary Structure 
TLGIGNDIIEIERIQANIKKYGQRFLNRVFTKNEQIYCLNRKMPALHLAGRFAAKEAVV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHH
KALGTGFSQGISWLDVEILNDANGKPYVSISPLLTQLFASPKLLISISHCHHYATAFAVW
HHHCCCHHHCCCEEEEEEEECCCCCCEEEHHHHHHHHHCCCEEEEEHHHHHHHHHHHEEE
SS
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA