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The map label for this gene is rkpK [H]

Identifier: 46447329

GI number: 46447329

Start: 2033509

End: 2034918

Strand: Direct

Name: rkpK [H]

Synonym: pc1695

Alternate gene names: 46447329

Gene position: 2033509-2034918 (Clockwise)

Preceding gene: 46447325

Following gene: 46447330

Centisome position: 84.22

GC content: 37.87

Gene sequence:

>1410_bases
TTGCTTTATTCGAAAGAAAGGACATGTATGAATCTTCTTATTATTGGTGTAGGATATGTAGGACTAGTGACGGCCACTTG
TTTTTCCGAAATGGGTTATTATGTCACTTGTTTGGATATTAATAAGGAAAAAATTGAACAATTAAAACTAGGCATGATCC
CTATTTATGAACCTGGGTTGGACGAAATGGTAAAACGCAACATAAAATCTAAGCGTTTGACTTTTACAACCAATTACTCC
TCTTCAGTTCCTCTCGCTAATATTTGCTTTATTGCTGTTGATACACCTACAACGCCACAAGGAGGAGCTGATACTTCTCA
AGTCGAATGTGTTGCAAAAACGTTGGGAGAGTTTATCAATCATTATTGTATTATTGTAACGAAATCTACAGTTCCTGTTG
GAACAACGCATCGAGTTTCTGCTATCATTCAAAATGCTTTAGAAAACAGAAATTGTCATGTGGAGTTTGATGTCGTTTCT
AACCCTGAATTTTTAAAAGAAGGAAATGCCGTTCAAGATTTTATGAAACCTGACCGAATCATTGTAGGATCGGATCACGC
TCGTTCAGCCAAAATCATGCGTGAATTATATTCTCCTTTTATGCTTAATCATGAACGCTTACTGGAAATGGATATTTTAT
CGGCAGAACTAGCAAAATATGCGGCTAATGCCATGTTAGCGACACGTATTTCCTTTATGAATGAAATGGCAAGGTTATGT
GAAAATGTGGGGGCGAATATTGGGTGGGTTCGTAAGGCAATGGGAGCTGACGATCGAATTGGACATAAATTTTTATATCC
TGGTGCAGGTTATGGTGGATCATGCCTGCCAAAAGATGTAAAAGCTCTAATTACTCAAGCGAAAGAATTGGGCCATCCTC
TTTCTTTATTAACGGCAGTGGATGAGATTAACCAACACCAAAAACATATCATAGGACAAAAAGTTAAAAATTACTTTGCC
GATCATGGAGGACTTAAAGGAAAAACCTTCGGAATTTTAGGCCTTTCATTCAAGCCCGATACAGATGACATGCGAGAAGC
TTCCTCATTAACTTTAATTAAAGATCTCATTGCAGAAGAAGCTTTATTAAAAGTTTATGATCCAGTCGCTATTCCGAAAG
CTCAACAAATACTTTCAGCTCATACTTGCATTACATGGTGCCAAACAGAACTCGAAGTAGCTGATCAAGCAGACGGCCTA
ATTTTAATGACAGAGTGGAAGCAGTTTCGATTCCTCGATTTTCCACTACTTTTAAAACGCATGAAAGGAAAAGCTTTTTT
TGATGGACGTAATCAATATCATCCGGAGGAAATGGCACGTAAAGGTTTCGATTATTTTAGTATTGGACGATCTGCAGCGT
ACGCAGAAGATCTCTCACTTCAAGTTGGAAATATAGGTGGCGATGTATGA

Upstream 100 bases:

>100_bases
TGATCGAAAACGTATTTATTCAAAAATAAACAACTTCTAAATAAATATGTTGTTTTAAAAACTATAAGCATGCAGCAAAA
ACGTTAAGTCAGTATAATAT

Downstream 100 bases:

>100_bases
TGGATGTTGCCAATTATTTACAAACACAAAGTCAGCTTATTGAAAAACGCCTGGATCAACTTGTCTCCAAACGTCACGGC
CCTCACCAAAATTTAATTGA

Product: udpglucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 469; Mature: 469

Protein sequence:

>469_residues
MLYSKERTCMNLLIIGVGYVGLVTATCFSEMGYYVTCLDINKEKIEQLKLGMIPIYEPGLDEMVKRNIKSKRLTFTTNYS
SSVPLANICFIAVDTPTTPQGGADTSQVECVAKTLGEFINHYCIIVTKSTVPVGTTHRVSAIIQNALENRNCHVEFDVVS
NPEFLKEGNAVQDFMKPDRIIVGSDHARSAKIMRELYSPFMLNHERLLEMDILSAELAKYAANAMLATRISFMNEMARLC
ENVGANIGWVRKAMGADDRIGHKFLYPGAGYGGSCLPKDVKALITQAKELGHPLSLLTAVDEINQHQKHIIGQKVKNYFA
DHGGLKGKTFGILGLSFKPDTDDMREASSLTLIKDLIAEEALLKVYDPVAIPKAQQILSAHTCITWCQTELEVADQADGL
ILMTEWKQFRFLDFPLLLKRMKGKAFFDGRNQYHPEEMARKGFDYFSIGRSAAYAEDLSLQVGNIGGDV

Sequences:

>Translated_469_residues
MLYSKERTCMNLLIIGVGYVGLVTATCFSEMGYYVTCLDINKEKIEQLKLGMIPIYEPGLDEMVKRNIKSKRLTFTTNYS
SSVPLANICFIAVDTPTTPQGGADTSQVECVAKTLGEFINHYCIIVTKSTVPVGTTHRVSAIIQNALENRNCHVEFDVVS
NPEFLKEGNAVQDFMKPDRIIVGSDHARSAKIMRELYSPFMLNHERLLEMDILSAELAKYAANAMLATRISFMNEMARLC
ENVGANIGWVRKAMGADDRIGHKFLYPGAGYGGSCLPKDVKALITQAKELGHPLSLLTAVDEINQHQKHIIGQKVKNYFA
DHGGLKGKTFGILGLSFKPDTDDMREASSLTLIKDLIAEEALLKVYDPVAIPKAQQILSAHTCITWCQTELEVADQADGL
ILMTEWKQFRFLDFPLLLKRMKGKAFFDGRNQYHPEEMARKGFDYFSIGRSAAYAEDLSLQVGNIGGDV
>Mature_469_residues
MLYSKERTCMNLLIIGVGYVGLVTATCFSEMGYYVTCLDINKEKIEQLKLGMIPIYEPGLDEMVKRNIKSKRLTFTTNYS
SSVPLANICFIAVDTPTTPQGGADTSQVECVAKTLGEFINHYCIIVTKSTVPVGTTHRVSAIIQNALENRNCHVEFDVVS
NPEFLKEGNAVQDFMKPDRIIVGSDHARSAKIMRELYSPFMLNHERLLEMDILSAELAKYAANAMLATRISFMNEMARLC
ENVGANIGWVRKAMGADDRIGHKFLYPGAGYGGSCLPKDVKALITQAKELGHPLSLLTAVDEINQHQKHIIGQKVKNYFA
DHGGLKGKTFGILGLSFKPDTDDMREASSLTLIKDLIAEEALLKVYDPVAIPKAQQILSAHTCITWCQTELEVADQADGL
ILMTEWKQFRFLDFPLLLKRMKGKAFFDGRNQYHPEEMARKGFDYFSIGRSAAYAEDLSLQVGNIGGDV

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=467, Percent_Identity=34.2612419700214, Blast_Score=246, Evalue=3e-65,
Organism=Homo sapiens, GI296040438, Length=373, Percent_Identity=33.5120643431635, Blast_Score=193, Evalue=3e-49,
Organism=Homo sapiens, GI296040443, Length=317, Percent_Identity=34.7003154574132, Blast_Score=175, Evalue=1e-43,
Organism=Escherichia coli, GI1788340, Length=363, Percent_Identity=29.4765840220386, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI48994968, Length=416, Percent_Identity=26.2019230769231, Blast_Score=132, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI17560350, Length=471, Percent_Identity=33.9702760084926, Blast_Score=237, Evalue=8e-63,
Organism=Drosophila melanogaster, GI17136908, Length=468, Percent_Identity=33.3333333333333, Blast_Score=244, Evalue=1e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 52176; Mature: 52176

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYSKERTCMNLLIIGVGYVGLVTATCFSEMGYYVTCLDINKEKIEQLKLGMIPIYEPGL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCCCCCCCCH
DEMVKRNIKSKRLTFTTNYSSSVPLANICFIAVDTPTTPQGGADTSQVECVAKTLGEFIN
HHHHHHCCCCCEEEEEECCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHC
HYCIIVTKSTVPVGTTHRVSAIIQNALENRNCHVEFDVVSNPEFLKEGNAVQDFMKPDRI
CEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHCCCHHHHHCCCCEE
IVGSDHARSAKIMRELYSPFMLNHERLLEMDILSAELAKYAANAMLATRISFMNEMARLC
EECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ENVGANIGWVRKAMGADDRIGHKFLYPGAGYGGSCLPKDVKALITQAKELGHPLSLLTAV
HHHCCCHHHHHHHCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHH
DEINQHQKHIIGQKVKNYFADHGGLKGKTFGILGLSFKPDTDDMREASSLTLIKDLIAEE
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
ALLKVYDPVAIPKAQQILSAHTCITWCQTELEVADQADGLILMTEWKQFRFLDFPLLLKR
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHCCCHHHHHHH
MKGKAFFDGRNQYHPEEMARKGFDYFSIGRSAAYAEDLSLQVGNIGGDV
HCCCEEECCCCCCCHHHHHHCCCCHHHCCCCHHHHHHCEEEECCCCCCC
>Mature Secondary Structure
MLYSKERTCMNLLIIGVGYVGLVTATCFSEMGYYVTCLDINKEKIEQLKLGMIPIYEPGL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCCCCCCCCH
DEMVKRNIKSKRLTFTTNYSSSVPLANICFIAVDTPTTPQGGADTSQVECVAKTLGEFIN
HHHHHHCCCCCEEEEEECCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHC
HYCIIVTKSTVPVGTTHRVSAIIQNALENRNCHVEFDVVSNPEFLKEGNAVQDFMKPDRI
CEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHCCCHHHHHCCCCEE
IVGSDHARSAKIMRELYSPFMLNHERLLEMDILSAELAKYAANAMLATRISFMNEMARLC
EECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ENVGANIGWVRKAMGADDRIGHKFLYPGAGYGGSCLPKDVKALITQAKELGHPLSLLTAV
HHHCCCHHHHHHHCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHH
DEINQHQKHIIGQKVKNYFADHGGLKGKTFGILGLSFKPDTDDMREASSLTLIKDLIAEE
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
ALLKVYDPVAIPKAQQILSAHTCITWCQTELEVADQADGLILMTEWKQFRFLDFPLLLKR
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHCCCHHHHHHH
MKGKAFFDGRNQYHPEEMARKGFDYFSIGRSAAYAEDLSLQVGNIGGDV
HCCCEEECCCCCCCHHHHHHCCCCHHHCCCCHHHHHHCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]