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The map label for this gene is oppC [H]

Identifier: 46447138

GI number: 46447138

Start: 1792666

End: 1793568

Strand: Direct

Name: oppC [H]

Synonym: pc1504

Alternate gene names: 46447138

Gene position: 1792666-1793568 (Clockwise)

Preceding gene: 46447137

Following gene: 46447139

Centisome position: 74.25

GC content: 38.65

Gene sequence:

>903_bases
ATGAAATCCTCCCCCTCTCAATCAGATTTTACTCCCTTGGAGAAGTGGGAAGAAACTTTTGTGCCGCCATCCTATAGCAG
ACCCTCTATTTTTAAACGTTTTCAATCTCATCCCTTAGGAATCGCGGGAATGCTTCTTTTTTTAGGAATTGTTATTTTAA
CGATTTTAGGACCTTTAATTTCTGGATATTCTCCCGAAACAACGCATCTGACTTTAAAAAATCACCCCCCTTCTTCACAG
TTTTGGTTTGGCACAGATGACCTTGGTCGCGATCTTTTTACGAGAGTTTGGTTTGGGGCTCGAATTTCTCTTTGTATTGG
TTTTTTAGCCGCCTCTATCGATCTAATTGTAGGATTAATTTGGGGCGGTATTGCCGGTTTTTCTGGAGGTAAAATTGATG
AAGCGATGATGCGATTTGTCGATATTTTATACGCTCTACCCTACTTACTTATCGTTATTTTGTTCACAGTAGTTTTAGGA
TCTGGCTTTTTCTCTATTGTCCTTGCTATTACATTATTTGGATGGATAACAATGGCTAGAATTGTTCGAGGGCAAATCCT
TTTAATTAAAGAAATGGATTATATTTTAGCTGAAAAAGTATTAGGAGCAAGTTTTTCGAGAATTTTATGGAAACACCTTC
TACCTAATGCCAGCGGACCCATCCTTGTTACTTTAACGTTAACGATTCCTTCCGCTATTTTTTCTGAAGCTTTTTTAAGT
TTTTTAGGGTTGGGTGTCCAAGCCCCAACAGCAAGTTGGGGCACAATGGCACATGAGGGATTGCCTGCCCTACAATATTA
CCCTTGGCGATTATTTTTTCCCGCTTTTTTGATTAGTTTGACTATGCTTTCTCTTCATTGGATTGGTGAAGGATTGAAAA
GCGCTTTTGATAAAACAGAGTAA

Upstream 100 bases:

>100_bases
CTCTTTTTTATAGCACTCTTTTGCTATTATCTGTCTTTATTGTTGATATCATTTACAGCTTATTAGACCCTCGCATTCAA
CTCATTCATAAGGAATTAGT

Downstream 100 bases:

>100_bases
GTTTTTTTATGATTCAGCCACTTGTTGACGTATGTCAGTTATTTCTCACCCTTGAAACTTTGCATGGTTCCCTCCATGCC
CTAAGAGGTGTTAATTTTCA

Product: oligo/dipeptide ABC transporter (permease) oppC

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: Stage 0 sporulation protein KC [H]

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MKSSPSQSDFTPLEKWEETFVPPSYSRPSIFKRFQSHPLGIAGMLLFLGIVILTILGPLISGYSPETTHLTLKNHPPSSQ
FWFGTDDLGRDLFTRVWFGARISLCIGFLAASIDLIVGLIWGGIAGFSGGKIDEAMMRFVDILYALPYLLIVILFTVVLG
SGFFSIVLAITLFGWITMARIVRGQILLIKEMDYILAEKVLGASFSRILWKHLLPNASGPILVTLTLTIPSAIFSEAFLS
FLGLGVQAPTASWGTMAHEGLPALQYYPWRLFFPAFLISLTMLSLHWIGEGLKSAFDKTE

Sequences:

>Translated_300_residues
MKSSPSQSDFTPLEKWEETFVPPSYSRPSIFKRFQSHPLGIAGMLLFLGIVILTILGPLISGYSPETTHLTLKNHPPSSQ
FWFGTDDLGRDLFTRVWFGARISLCIGFLAASIDLIVGLIWGGIAGFSGGKIDEAMMRFVDILYALPYLLIVILFTVVLG
SGFFSIVLAITLFGWITMARIVRGQILLIKEMDYILAEKVLGASFSRILWKHLLPNASGPILVTLTLTIPSAIFSEAFLS
FLGLGVQAPTASWGTMAHEGLPALQYYPWRLFFPAFLISLTMLSLHWIGEGLKSAFDKTE
>Mature_300_residues
MKSSPSQSDFTPLEKWEETFVPPSYSRPSIFKRFQSHPLGIAGMLLFLGIVILTILGPLISGYSPETTHLTLKNHPPSSQ
FWFGTDDLGRDLFTRVWFGARISLCIGFLAASIDLIVGLIWGGIAGFSGGKIDEAMMRFVDILYALPYLLIVILFTVVLG
SGFFSIVLAITLFGWITMARIVRGQILLIKEMDYILAEKVLGASFSRILWKHLLPNASGPILVTLTLTIPSAIFSEAFLS
FLGLGVQAPTASWGTMAHEGLPALQYYPWRLFFPAFLISLTMLSLHWIGEGLKSAFDKTE

Specific function: Part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the substrate across the membrane. Also required for sporulation and competence [H]

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787498, Length=298, Percent_Identity=36.9127516778523, Blast_Score=183, Evalue=1e-47,
Organism=Escherichia coli, GI1787054, Length=267, Percent_Identity=37.4531835205993, Blast_Score=180, Evalue=8e-47,
Organism=Escherichia coli, GI1787760, Length=290, Percent_Identity=32.7586206896552, Blast_Score=165, Evalue=4e-42,
Organism=Escherichia coli, GI1789889, Length=235, Percent_Identity=33.1914893617021, Blast_Score=141, Evalue=5e-35,
Organism=Escherichia coli, GI1789964, Length=251, Percent_Identity=36.2549800796813, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1788505, Length=226, Percent_Identity=35.3982300884956, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1787549, Length=280, Percent_Identity=28.9285714285714, Blast_Score=117, Evalue=7e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33185; Mature: 33185

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSSPSQSDFTPLEKWEETFVPPSYSRPSIFKRFQSHPLGIAGMLLFLGIVILTILGPLI
CCCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
SGYSPETTHLTLKNHPPSSQFWFGTDDLGRDLFTRVWFGARISLCIGFLAASIDLIVGLI
CCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WGGIAGFSGGKIDEAMMRFVDILYALPYLLIVILFTVVLGSGFFSIVLAITLFGWITMAR
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
IVRGQILLIKEMDYILAEKVLGASFSRILWKHLLPNASGPILVTLTLTIPSAIFSEAFLS
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHH
FLGLGVQAPTASWGTMAHEGLPALQYYPWRLFFPAFLISLTMLSLHWIGEGLKSAFDKTE
HHHCCCCCCCCCHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKSSPSQSDFTPLEKWEETFVPPSYSRPSIFKRFQSHPLGIAGMLLFLGIVILTILGPLI
CCCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
SGYSPETTHLTLKNHPPSSQFWFGTDDLGRDLFTRVWFGARISLCIGFLAASIDLIVGLI
CCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WGGIAGFSGGKIDEAMMRFVDILYALPYLLIVILFTVVLGSGFFSIVLAITLFGWITMAR
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
IVRGQILLIKEMDYILAEKVLGASFSRILWKHLLPNASGPILVTLTLTIPSAIFSEAFLS
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHH
FLGLGVQAPTASWGTMAHEGLPALQYYPWRLFFPAFLISLTMLSLHWIGEGLKSAFDKTE
HHHCCCCCCCCCHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1901616; 1899858; 9384377 [H]