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The map label for this gene is hrcA

Identifier: 46447131

GI number: 46447131

Start: 1784377

End: 1785534

Strand: Direct

Name: hrcA

Synonym: pc1497

Alternate gene names: 46447131

Gene position: 1784377-1785534 (Clockwise)

Preceding gene: 46447130

Following gene: 46447132

Centisome position: 73.9

GC content: 36.7

Gene sequence:

>1158_bases
TTGAAAATCATCAAACCAACACCGATTAAACGCGTGGGTAAACACGATCGAGAAAGACGGGTTTTATTAGGCTTAGTCGA
TTACTATATTCAAACTGGAAAACCCGTTGGATCCAACACTTTAAAAGAAGCTGGATTTGAAGATTTGAGCTCTGCAACCA
TTCGTAATTATTTTGCCCAACTTGAAGAAGAAGGATATTTATTACAATCACACTCTTCTGGTGGCCGCATTCCTACGGAT
TTAGCCTATCGAATTTATGCTCATGCTTATCTCAATACCAATGAACCTTATCCTAAGCAAAATCCTTTTGAAGCTTTTAA
AAGTTTTGAATCAAAGGAAATCGCTATCTTTTTGCAAGAAGCTGCAGAAAAACTTAGCTGGGAAACTAATTGTGCTGTTT
TCCTTTCTGCCCCTCGGTTTGATCACGATTTTATCGCTAACCTCAAGCTAGTTCCATTAGATGCCTATCGGTGCCTTTGC
ATTATTATGACGGATTTTGGAGTTATTAAAACTGAAGTCATGCATTTGCCAGTTAAACTCTCTTCTTTTGGAATCAAACG
CATTGAGAATTATTTTCATTGCCGCTTAACGAATTTAGGAGAACCTGAAAATTTAGAGCCTGAGGAAGAAACTGTTGCTC
AAACTTTTTATAATGAATTAATGCTTAGATATATCGTTGGTTATTCAAATTTTATTGATGTGGATCTTTACCGAACTGGC
TTTTCTCGCCTGCTCTTTTACTCAGATTTTCAGGATACCAACTTACTTGCAAGCAGCCTATCTTTATTCGAGAATGCACA
TAGCATGCGCCTTCTTTTAAAAGAATGCAAAGCCTTAAATCATTTAAGATTTTGGATTGGGGATGATCTGTCCTCTTTTG
CAAATTCGAGCCCTAGATGTAGTGTTTTAACTATCCCTTATTATATCAATTACAAGCCAGTCGGCGCAGTAGGCTTATTA
GGCCCAACAAGACTGCCTTATCGAGCATTGTTCAGTTTATTAAAGCTATTTTCTGATTGTATTAGCGAAACTGTTACAAA
AAATGTTTACAAATTCAAAATTGACTACAGGCAACCTGAGCAAAGCTTATATTTGAAAAAAGAAGAAAGTTTACTGATTG
GTCAATCACGTTTCCTCATCGAAGATAAGCGACCATGA

Upstream 100 bases:

>100_bases
AAGAAAAATTATAGCACTCGATATAATCGAGTGCTAAATTTGTTTGACGAAATTTTCCCTCTTTGCGTATAATAACAAAA
TTATTAGGGAGGATTCGCTC

Downstream 100 bases:

>100_bases
AGTTATATAGACCAGAATGATAAAGGAGAAAAAAGAAATGGTTGACAAAGACGAAGAGCAAATAAAACAAAACGTAGAGG
AAGATTTATCTTCGACAGTA

Product: heat-inducible transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MKIIKPTPIKRVGKHDRERRVLLGLVDYYIQTGKPVGSNTLKEAGFEDLSSATIRNYFAQLEEEGYLLQSHSSGGRIPTD
LAYRIYAHAYLNTNEPYPKQNPFEAFKSFESKEIAIFLQEAAEKLSWETNCAVFLSAPRFDHDFIANLKLVPLDAYRCLC
IIMTDFGVIKTEVMHLPVKLSSFGIKRIENYFHCRLTNLGEPENLEPEEETVAQTFYNELMLRYIVGYSNFIDVDLYRTG
FSRLLFYSDFQDTNLLASSLSLFENAHSMRLLLKECKALNHLRFWIGDDLSSFANSSPRCSVLTIPYYINYKPVGAVGLL
GPTRLPYRALFSLLKLFSDCISETVTKNVYKFKIDYRQPEQSLYLKKEESLLIGQSRFLIEDKRP

Sequences:

>Translated_385_residues
MKIIKPTPIKRVGKHDRERRVLLGLVDYYIQTGKPVGSNTLKEAGFEDLSSATIRNYFAQLEEEGYLLQSHSSGGRIPTD
LAYRIYAHAYLNTNEPYPKQNPFEAFKSFESKEIAIFLQEAAEKLSWETNCAVFLSAPRFDHDFIANLKLVPLDAYRCLC
IIMTDFGVIKTEVMHLPVKLSSFGIKRIENYFHCRLTNLGEPENLEPEEETVAQTFYNELMLRYIVGYSNFIDVDLYRTG
FSRLLFYSDFQDTNLLASSLSLFENAHSMRLLLKECKALNHLRFWIGDDLSSFANSSPRCSVLTIPYYINYKPVGAVGLL
GPTRLPYRALFSLLKLFSDCISETVTKNVYKFKIDYRQPEQSLYLKKEESLLIGQSRFLIEDKRP
>Mature_385_residues
MKIIKPTPIKRVGKHDRERRVLLGLVDYYIQTGKPVGSNTLKEAGFEDLSSATIRNYFAQLEEEGYLLQSHSSGGRIPTD
LAYRIYAHAYLNTNEPYPKQNPFEAFKSFESKEIAIFLQEAAEKLSWETNCAVFLSAPRFDHDFIANLKLVPLDAYRCLC
IIMTDFGVIKTEVMHLPVKLSSFGIKRIENYFHCRLTNLGEPENLEPEEETVAQTFYNELMLRYIVGYSNFIDVDLYRTG
FSRLLFYSDFQDTNLLASSLSLFENAHSMRLLLKECKALNHLRFWIGDDLSSFANSSPRCSVLTIPYYINYKPVGAVGLL
GPTRLPYRALFSLLKLFSDCISETVTKNVYKFKIDYRQPEQSLYLKKEESLLIGQSRFLIEDKRP

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HRCA_PARUW (Q6MB28)

Other databases:

- EMBL:   BX908798
- RefSeq:   YP_008496.1
- ProteinModelPortal:   Q6MB28
- SMR:   Q6MB28
- STRING:   Q6MB28
- GeneID:   2780652
- GenomeReviews:   BX908798_GR
- KEGG:   pcu:pc1497
- NMPDR:   fig|264201.1.peg.1497
- eggNOG:   COG1420
- HOGENOM:   HBG414062
- OMA:   VHYKLRT
- ProtClustDB:   PRK00082
- BioCyc:   CPRO264201:PC1497-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00081
- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PIRSF:   PIRSF005485
- TIGRFAMs:   TIGR00331

Pfam domain/function: PF01628 HrcA

EC number: NA

Molecular weight: Translated: 44393; Mature: 44393

Theoretical pI: Translated: 7.49; Mature: 7.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIKPTPIKRVGKHDRERRVLLGLVDYYIQTGKPVGSNTLKEAGFEDLSSATIRNYFAQ
CCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHHHHHHHHHHH
LEEEGYLLQSHSSGGRIPTDLAYRIYAHAYLNTNEPYPKQNPFEAFKSFESKEIAIFLQE
HHCCCCEEEECCCCCCCCHHHHHEEEEEEEECCCCCCCCCCHHHHHHCCCCCHHHHHHHH
AAEKLSWETNCAVFLSAPRFDHDFIANLKLVPLDAYRCLCIIMTDFGVIKTEVMHLPVKL
HHHHCCCCCCEEEEEECCCCCCHHHCCCEEEEEHHHHEEHHHHHCCCHHHHHHHHCCEEH
SSFGIKRIENYFHCRLTNLGEPENLEPEEETVAQTFYNELMLRYIVGYSNFIDVDLYRTG
HHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHH
FSRLLFYSDFQDTNLLASSLSLFENAHSMRLLLKECKALNHLRFWIGDDLSSFANSSPRC
HHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCE
SVLTIPYYINYKPVGAVGLLGPTRLPYRALFSLLKLFSDCISETVTKNVYKFKIDYRQPE
EEEEEEEEEECCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCC
QSLYLKKEESLLIGQSRFLIEDKRP
HHEEEECCCCEEECCCEEEEECCCC
>Mature Secondary Structure
MKIIKPTPIKRVGKHDRERRVLLGLVDYYIQTGKPVGSNTLKEAGFEDLSSATIRNYFAQ
CCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHHHHHHHHHHH
LEEEGYLLQSHSSGGRIPTDLAYRIYAHAYLNTNEPYPKQNPFEAFKSFESKEIAIFLQE
HHCCCCEEEECCCCCCCCHHHHHEEEEEEEECCCCCCCCCCHHHHHHCCCCCHHHHHHHH
AAEKLSWETNCAVFLSAPRFDHDFIANLKLVPLDAYRCLCIIMTDFGVIKTEVMHLPVKL
HHHHCCCCCCEEEEEECCCCCCHHHCCCEEEEEHHHHEEHHHHHCCCHHHHHHHHCCEEH
SSFGIKRIENYFHCRLTNLGEPENLEPEEETVAQTFYNELMLRYIVGYSNFIDVDLYRTG
HHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHH
FSRLLFYSDFQDTNLLASSLSLFENAHSMRLLLKECKALNHLRFWIGDDLSSFANSSPRC
HHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCE
SVLTIPYYINYKPVGAVGLLGPTRLPYRALFSLLKLFSDCISETVTKNVYKFKIDYRQPE
EEEEEEEEEECCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCC
QSLYLKKEESLLIGQSRFLIEDKRP
HHEEEECCCCEEECCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA