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The map label for this gene is yrkA [H]

Identifier: 46447117

GI number: 46447117

Start: 1758163

End: 1759191

Strand: Direct

Name: yrkA [H]

Synonym: pc1483

Alternate gene names: 46447117

Gene position: 1758163-1759191 (Clockwise)

Preceding gene: 46447116

Following gene: 161611303

Centisome position: 72.82

GC content: 36.15

Gene sequence:

>1029_bases
ATGTTTGAAATTTTATTGATTTTAATGTGTTTGATTCTTAATGCATTTTTAGCTGGAGCAGAAACAGCTTTTATTGCAGT
TAGTAAATCAACTTTGAGAGAATGGATTAAAAAGGGGCATGCAAGAGCTAAATTGCTTTTAACTTTACGCGAAAATCCAG
AGAGAACTCTATCTGTTATTCAAATAGGAATTACTTTTTTGGGGGCATTTGCAGCAGCTTTAGGGGGTGCTGGCGCCGAA
GAAACCATTACTCCTTGGCTAACTTCTACGTTTAGATTGACTGAGACTTTAGCTGAAATTCTTTCGTTGATGATTGTTGT
TGTTCCTTTAACTTTCGTTAGCGTAGTAGTTGGAGAGCTTGTTCCCAAAACTCTGGCATTAAGACGCCCTTTATTTTTTG
CTTCGAAATCTGCACCTTGGCTCTTTCAGGCCAGCCGATTTATCAGCCCTATTGTTTCTTCGCTTGAATGGTCGACCAAA
ATGGTTTTAGCCTCTTTTCCAAAACACCACATTGTGAGTGAAGAAAGTCAAGAGGAATCAAATTTTCCCTTAGAACATCT
TTCAACGTTCGATAAACAATACATTTTTAATATTGTTAAGGTTGAAAAAACAACTGTCAGAGAAATTTTTGTTAGTTGGC
CTGAAGTTGTTAGCGTTAACAGTGCTCAAACATTGTCCGAAGTAGAAAACATTGTCATCTCATCAGGTCATACACGCTTA
CCTGTTTTACAAGATCAAGAAGTTATGGGAATTATCAACGCTAAAGAATTTTTAGCTTTTCAAAAAACTGGGCAACAAAA
TTGGATGTCTATTGTTCGTCCCCCCCTTAAAATTGAAGATAAATTACCCATTCTCTCTGCTCTTCGTTTTATGCAAGATC
ATCGGAGTCATATGGCTATTGTCTATCAAGGAAAAAATAAAAGTGGAATTGTTACCATGGAAGCTATTTTCGAAGAAATA
GTCGGTGATATTTACGATGAAGAAGATGATGGATCATTAAAAAGAATCTTGGGTCGTTCTATAAAATAA

Upstream 100 bases:

>100_bases
AGGGTAGATGGAAAATAAATTTTTTTATCCCTAAATCCAAATCTCAAAGAAAAAACTTTAAATTCAAGTTACTAGATCAA
ATCGTTATAAAGTGCAAATT

Downstream 100 bases:

>100_bases
TTTGTAAAATTAGAAGAATTTTTTTATTATTCTACATCTGAAAGAGTCATATGATCATCATCTTTTTCTTCGTAAGTGAG
AAGTTCAATTAGTTCATTTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MFEILLILMCLILNAFLAGAETAFIAVSKSTLREWIKKGHARAKLLLTLRENPERTLSVIQIGITFLGAFAAALGGAGAE
ETITPWLTSTFRLTETLAEILSLMIVVVPLTFVSVVVGELVPKTLALRRPLFFASKSAPWLFQASRFISPIVSSLEWSTK
MVLASFPKHHIVSEESQEESNFPLEHLSTFDKQYIFNIVKVEKTTVREIFVSWPEVVSVNSAQTLSEVENIVISSGHTRL
PVLQDQEVMGIINAKEFLAFQKTGQQNWMSIVRPPLKIEDKLPILSALRFMQDHRSHMAIVYQGKNKSGIVTMEAIFEEI
VGDIYDEEDDGSLKRILGRSIK

Sequences:

>Translated_342_residues
MFEILLILMCLILNAFLAGAETAFIAVSKSTLREWIKKGHARAKLLLTLRENPERTLSVIQIGITFLGAFAAALGGAGAE
ETITPWLTSTFRLTETLAEILSLMIVVVPLTFVSVVVGELVPKTLALRRPLFFASKSAPWLFQASRFISPIVSSLEWSTK
MVLASFPKHHIVSEESQEESNFPLEHLSTFDKQYIFNIVKVEKTTVREIFVSWPEVVSVNSAQTLSEVENIVISSGHTRL
PVLQDQEVMGIINAKEFLAFQKTGQQNWMSIVRPPLKIEDKLPILSALRFMQDHRSHMAIVYQGKNKSGIVTMEAIFEEI
VGDIYDEEDDGSLKRILGRSIK
>Mature_342_residues
MFEILLILMCLILNAFLAGAETAFIAVSKSTLREWIKKGHARAKLLLTLRENPERTLSVIQIGITFLGAFAAALGGAGAE
ETITPWLTSTFRLTETLAEILSLMIVVVPLTFVSVVVGELVPKTLALRRPLFFASKSAPWLFQASRFISPIVSSLEWSTK
MVLASFPKHHIVSEESQEESNFPLEHLSTFDKQYIFNIVKVEKTTVREIFVSWPEVVSVNSAQTLSEVENIVISSGHTRL
PVLQDQEVMGIINAKEFLAFQKTGQQNWMSIVRPPLKIEDKLPILSALRFMQDHRSHMAIVYQGKNKSGIVTMEAIFEEI
VGDIYDEEDDGSLKRILGRSIK

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=347, Percent_Identity=26.5129682997118, Blast_Score=110, Evalue=3e-24,
Organism=Escherichia coli, GI145693175, Length=329, Percent_Identity=24.3161094224924, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1790664, Length=344, Percent_Identity=21.8023255813953, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 38302; Mature: 38302

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEILLILMCLILNAFLAGAETAFIAVSKSTLREWIKKGHARAKLLLTLRENPERTLSVI
CHHHHHHHHHHHHHHHHCCCCHHEEEECHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHH
QIGITFLGAFAAALGGAGAEETITPWLTSTFRLTETLAEILSLMIVVVPLTFVSVVVGEL
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPKTLALRRPLFFASKSAPWLFQASRFISPIVSSLEWSTKMVLASFPKHHIVSEESQEES
HHHHHHHHCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCC
NFPLEHLSTFDKQYIFNIVKVEKTTVREIFVSWPEVVSVNSAQTLSEVENIVISSGHTRL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHCCCCCCC
PVLQDQEVMGIINAKEFLAFQKTGQQNWMSIVRPPLKIEDKLPILSALRFMQDHRSHMAI
CCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEE
VYQGKNKSGIVTMEAIFEEIVGDIYDEEDDGSLKRILGRSIK
EEECCCCCCCEEHHHHHHHHHHHHCCCCCCCHHHHHHCCCCC
>Mature Secondary Structure
MFEILLILMCLILNAFLAGAETAFIAVSKSTLREWIKKGHARAKLLLTLRENPERTLSVI
CHHHHHHHHHHHHHHHHCCCCHHEEEECHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHH
QIGITFLGAFAAALGGAGAEETITPWLTSTFRLTETLAEILSLMIVVVPLTFVSVVVGEL
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPKTLALRRPLFFASKSAPWLFQASRFISPIVSSLEWSTKMVLASFPKHHIVSEESQEES
HHHHHHHHCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCC
NFPLEHLSTFDKQYIFNIVKVEKTTVREIFVSWPEVVSVNSAQTLSEVENIVISSGHTRL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHCCCCCCC
PVLQDQEVMGIINAKEFLAFQKTGQQNWMSIVRPPLKIEDKLPILSALRFMQDHRSHMAI
CCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEE
VYQGKNKSGIVTMEAIFEEIVGDIYDEEDDGSLKRILGRSIK
EEECCCCCCCEEHHHHHHHHHHHHCCCCCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9308178; 9384377; 8969508; 7608059 [H]