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The map label for this gene is accA

Identifier: 46446798

GI number: 46446798

Start: 1392164

End: 1393114

Strand: Reverse

Name: accA

Synonym: pc1164

Alternate gene names: 46446798

Gene position: 1393114-1392164 (Counterclockwise)

Preceding gene: 46446799

Following gene: 46446797

Centisome position: 57.7

GC content: 38.17

Gene sequence:

>951_bases
TTGGATATTTTACCCCATGAAAAGCAAATTCATGAGTATATCAAAACGATTGAGCACCTCAAAAAACAAAGTCAAGACAA
TCCAATTTTTGATGTTGAAATTCAAAAATTAGAGCAGAAATTAGATAGTCTCAAACAACATGTCTATTCCGAATTGACCC
CTTGGCAAAGAATTATGATTTGTCGCCATCCCTCTCGACCGCACGCTGTCGATTTTATTCGCCATCTTTCAGAAAGTTTT
GTAGAACTGGCTGGTGATCGCAGTTACAGAGAAGATCATGCGATTGTCGGAGGTTTGGCCAAAATTGGAGGAATCAAATG
CGTTGTTATTGGACAAGAAAAAGGTTTTGATACAGAGAGTCGAGTTTATCGAAACTTTGGAATGTTAAATCCTGAGGGCT
TTCGTAAAGCTTTACGTTTAATGCAAATGGCTGAGAAATTTCAATTACCTATTATTTCCCTTTTAGATACACCAGGGGCA
TATCCAGGCCTTGAAGCAGAAGAACGTGGCCAAGGATGGGCGATTGCTCGAAATCTTCGTGAAATGATGCGTATTAATAC
TCCAATCATTATTACAATTATCGGGGAAGGATGTTCGGGAGGAGCACTTGGAATGGGAATAGGAGACGTCATTGGAATGT
TAGAACATGCCTATTATTCCGTTATTTCTCCAGAAGGATGTGCGTCAATCCTTTGGAAGGATGCCTCTAAAAACGTCGAA
GCCGCCTCTGCCCTTAAATTGAATGCTGAAGATCTTTTGAATCTTAAAATCATTGATAGTATTATTAAAGAACCCCTTGG
TGGAGCTCATCATGATCCTCACATAACTTACCAAAATGTCAAACAATTTTTAGTTGAACAGTTACATATCCTTAGACGAA
TTCCTTCTCAAATTTTACTTGAACAACGTTATTTGAAATTTCGTCAAATGGGAGAATTTTTAGAGGGTTAA

Upstream 100 bases:

>100_bases
GAGATTTTTCTGAGGCGACCTTACCAGGAATACTGGATTAAATAAATCCTAAATTATTAAAAATTAAATAGATAGAACCT
TTAAAGGAAGGAGTACTCCG

Downstream 100 bases:

>100_bases
AAGTTTTATGCGTTTGTTAATGAAAACAGCATTAATGGGAAAGCAACACCGTTTTCTGATTATCCTAACAATTTTATCAA
TGATCTTTTTAACGATTGCC

Product: acetyl-CoA carboxylase carboxyltransferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MDILPHEKQIHEYIKTIEHLKKQSQDNPIFDVEIQKLEQKLDSLKQHVYSELTPWQRIMICRHPSRPHAVDFIRHLSESF
VELAGDRSYREDHAIVGGLAKIGGIKCVVIGQEKGFDTESRVYRNFGMLNPEGFRKALRLMQMAEKFQLPIISLLDTPGA
YPGLEAEERGQGWAIARNLREMMRINTPIIITIIGEGCSGGALGMGIGDVIGMLEHAYYSVISPEGCASILWKDASKNVE
AASALKLNAEDLLNLKIIDSIIKEPLGGAHHDPHITYQNVKQFLVEQLHILRRIPSQILLEQRYLKFRQMGEFLEG

Sequences:

>Translated_316_residues
MDILPHEKQIHEYIKTIEHLKKQSQDNPIFDVEIQKLEQKLDSLKQHVYSELTPWQRIMICRHPSRPHAVDFIRHLSESF
VELAGDRSYREDHAIVGGLAKIGGIKCVVIGQEKGFDTESRVYRNFGMLNPEGFRKALRLMQMAEKFQLPIISLLDTPGA
YPGLEAEERGQGWAIARNLREMMRINTPIIITIIGEGCSGGALGMGIGDVIGMLEHAYYSVISPEGCASILWKDASKNVE
AASALKLNAEDLLNLKIIDSIIKEPLGGAHHDPHITYQNVKQFLVEQLHILRRIPSQILLEQRYLKFRQMGEFLEG
>Mature_316_residues
MDILPHEKQIHEYIKTIEHLKKQSQDNPIFDVEIQKLEQKLDSLKQHVYSELTPWQRIMICRHPSRPHAVDFIRHLSESF
VELAGDRSYREDHAIVGGLAKIGGIKCVVIGQEKGFDTESRVYRNFGMLNPEGFRKALRLMQMAEKFQLPIISLLDTPGA
YPGLEAEERGQGWAIARNLREMMRINTPIIITIIGEGCSGGALGMGIGDVIGMLEHAYYSVISPEGCASILWKDASKNVE
AASALKLNAEDLLNLKIIDSIIKEPLGGAHHDPHITYQNVKQFLVEQLHILRRIPSQILLEQRYLKFRQMGEFLEG

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family

Homologues:

Organism=Escherichia coli, GI1786382, Length=315, Percent_Identity=47.9365079365079, Blast_Score=307, Evalue=7e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCA_PARUW (Q6MC11)

Other databases:

- EMBL:   BX908798
- RefSeq:   YP_008163.1
- ProteinModelPortal:   Q6MC11
- SMR:   Q6MC11
- STRING:   Q6MC11
- GeneID:   2779848
- GenomeReviews:   BX908798_GR
- KEGG:   pcu:pc1164
- NMPDR:   fig|264201.1.peg.1164
- eggNOG:   COG0825
- HOGENOM:   HBG286557
- OMA:   QLTKDIY
- PhylomeDB:   Q6MC11
- ProtClustDB:   PRK05724
- BioCyc:   CPRO264201:PC1164-MONOMER
- HAMAP:   MF_00823
- InterPro:   IPR001095
- InterPro:   IPR011763
- PANTHER:   PTHR22855:SF3
- PRINTS:   PR01069
- TIGRFAMs:   TIGR00513

Pfam domain/function: PF03255 ACCA

EC number: =6.4.1.2

Molecular weight: Translated: 35826; Mature: 35826

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDILPHEKQIHEYIKTIEHLKKQSQDNPIFDVEIQKLEQKLDSLKQHVYSELTPWQRIMI
CCCCCCHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
CRHPSRPHAVDFIRHLSESFVELAGDRSYREDHAIVGGLAKIGGIKCVVIGQEKGFDTES
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCHHH
RVYRNFGMLNPEGFRKALRLMQMAEKFQLPIISLLDTPGAYPGLEAEERGQGWAIARNLR
HHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCHHHCCCCHHHHHHHH
EMMRINTPIIITIIGEGCSGGALGMGIGDVIGMLEHAYYSVISPEGCASILWKDASKNVE
HHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCH
AASALKLNAEDLLNLKIIDSIIKEPLGGAHHDPHITYQNVKQFLVEQLHILRRIPSQILL
HHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EQRYLKFRQMGEFLEG
HHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDILPHEKQIHEYIKTIEHLKKQSQDNPIFDVEIQKLEQKLDSLKQHVYSELTPWQRIMI
CCCCCCHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
CRHPSRPHAVDFIRHLSESFVELAGDRSYREDHAIVGGLAKIGGIKCVVIGQEKGFDTES
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCHHH
RVYRNFGMLNPEGFRKALRLMQMAEKFQLPIISLLDTPGAYPGLEAEERGQGWAIARNLR
HHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCHHHCCCCHHHHHHHH
EMMRINTPIIITIIGEGCSGGALGMGIGDVIGMLEHAYYSVISPEGCASILWKDASKNVE
HHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCH
AASALKLNAEDLLNLKIIDSIIKEPLGGAHHDPHITYQNVKQFLVEQLHILRRIPSQILL
HHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EQRYLKFRQMGEFLEG
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA