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The map label for this gene is fabI [H]

Identifier: 46446786

GI number: 46446786

Start: 1381433

End: 1382344

Strand: Direct

Name: fabI [H]

Synonym: pc1152

Alternate gene names: 46446786

Gene position: 1381433-1382344 (Clockwise)

Preceding gene: 46446784

Following gene: 46446793

Centisome position: 57.21

GC content: 41.23

Gene sequence:

>912_bases
ATGCAAATCAATTTAAAGGGAAAAAAAGCTTTTATTGCTGGAGTAGGAGATGATCAAGGCTTTGGATGGGCCATTGCTAA
AGCCCTTGCCGAAGCAGGAGCGGAAATCATTATCGGAACTTGGACTCCTATTTTGAAGATTTTTACTTCTAGCTTGCAGG
CGGGAAAATTTGATGCTTCACGCCGTTTACCTAATGGATCTTTACTTACTTTTGCTAAAATTTATCCCCTAGATGCTTCT
TTTGATAAACCCGAAGATGTTCCAGAAGAAATTAGGGAGAACAAAAGATATAAGGGTGTTGGAGGCTATACCATTTCTGA
GGTCTGCGAAGCAATTGGAAAGGATTTTGGAAAGATAGATATTTTCGTCCATTCCCTTGCCAACGCACCTGAAGTACAAA
AACCCTTATTAGAAACAAGCCGAAAAGGATATCTAGCAGCTCTTAGCTCTTCCTCTTATTCATTTGTGAGTTTATTGTCT
CATCTTGGACCTTATCTCAATTCTCAAGGGTCAGCCTTAACTCTGACTTACCTCGCCTCAGAAAAAATTATTCCAGGCTA
TGGAGGCGGTATGAGCTCTGCGAAAGCGGCTTTAGAGAGTGATACCAGGACTTTAGCCTGGGAAGCCGGCAGAAAATGGA
ATATTCGCGTAAATACCATTTCGGCTGGCCCCCTACGAAGTCGTGCAGCTAGAGCAATTGGTTTTATTGATCGTATGATT
AATTATTCTCAAGTGAATGCTCCCCTTCAAGAAGAGCTTAAAGCTTGTGAAGTGGCAAATGTTGCGGCTTTTTTAGGATC
AGATTTAGCCTGTGCAATTACTGGATCTACAATTTATGTAGATTACGGCCTTCATGCGATGGGAGTAGGAATGGATAGCC
CAACTTTAAAAGAAGCAGAACAAGAAGTTTAA

Upstream 100 bases:

>100_bases
ATAAACACCTTTGTAGCTCTAAAAAAAACTTCGACAAACTTATAAGTAAAATCTTACAATGGAGCCCACTTAAAATTTTC
TATAATAAGGAGTTTCTCAA

Downstream 100 bases:

>100_bases
TTTTTTTAATGAAAAATATGCTTTCAACGAATGAAATTTTTCTTTCGAAAAATTTCATTCGGACTATATGTAATAGAAAG
AAATTTAAATAAAATATTTT

Product: enoyl-(acyl carrier protein) reductase

Products: NA

Alternate protein names: NADH-dependent enoyl-ACP reductase [H]

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MQINLKGKKAFIAGVGDDQGFGWAIAKALAEAGAEIIIGTWTPILKIFTSSLQAGKFDASRRLPNGSLLTFAKIYPLDAS
FDKPEDVPEEIRENKRYKGVGGYTISEVCEAIGKDFGKIDIFVHSLANAPEVQKPLLETSRKGYLAALSSSSYSFVSLLS
HLGPYLNSQGSALTLTYLASEKIIPGYGGGMSSAKAALESDTRTLAWEAGRKWNIRVNTISAGPLRSRAARAIGFIDRMI
NYSQVNAPLQEELKACEVANVAAFLGSDLACAITGSTIYVDYGLHAMGVGMDSPTLKEAEQEV

Sequences:

>Translated_303_residues
MQINLKGKKAFIAGVGDDQGFGWAIAKALAEAGAEIIIGTWTPILKIFTSSLQAGKFDASRRLPNGSLLTFAKIYPLDAS
FDKPEDVPEEIRENKRYKGVGGYTISEVCEAIGKDFGKIDIFVHSLANAPEVQKPLLETSRKGYLAALSSSSYSFVSLLS
HLGPYLNSQGSALTLTYLASEKIIPGYGGGMSSAKAALESDTRTLAWEAGRKWNIRVNTISAGPLRSRAARAIGFIDRMI
NYSQVNAPLQEELKACEVANVAAFLGSDLACAITGSTIYVDYGLHAMGVGMDSPTLKEAEQEV
>Mature_303_residues
MQINLKGKKAFIAGVGDDQGFGWAIAKALAEAGAEIIIGTWTPILKIFTSSLQAGKFDASRRLPNGSLLTFAKIYPLDAS
FDKPEDVPEEIRENKRYKGVGGYTISEVCEAIGKDFGKIDIFVHSLANAPEVQKPLLETSRKGYLAALSSSSYSFVSLLS
HLGPYLNSQGSALTLTYLASEKIIPGYGGGMSSAKAALESDTRTLAWEAGRKWNIRVNTISAGPLRSRAARAIGFIDRMI
NYSQVNAPLQEELKACEVANVAAFLGSDLACAITGSTIYVDYGLHAMGVGMDSPTLKEAEQEV

Specific function: Fatty acid biosynthesis pathway; second reduction step. [C]

COG id: COG0623

COG function: function code I; Enoyl-[acyl-carrier-protein] reductase (NADH)

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787545, Length=283, Percent_Identity=31.4487632508834, Blast_Score=110, Evalue=1e-25,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR014358
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.3.1.9 [H]

Molecular weight: Translated: 32467; Mature: 32467

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQINLKGKKAFIAGVGDDQGFGWAIAKALAEAGAEIIIGTWTPILKIFTSSLQAGKFDAS
CEEECCCCEEEEEECCCCCCCHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHCCCCCCHH
RRLPNGSLLTFAKIYPLDASFDKPEDVPEEIRENKRYKGVGGYTISEVCEAIGKDFGKID
HCCCCCCEEEEEEEEECCCCCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCHH
IFVHSLANAPEVQKPLLETSRKGYLAALSSSSYSFVSLLSHLGPYLNSQGSALTLTYLAS
HHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEC
EKIIPGYGGGMSSAKAALESDTRTLAWEAGRKWNIRVNTISAGPLRSRAARAIGFIDRMI
CCCCCCCCCCHHHHHHHHHCCCCEEEECCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHH
NYSQVNAPLQEELKACEVANVAAFLGSDLACAITGSTIYVDYGLHAMGVGMDSPTLKEAE
HHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEEEECCEEEECCCCCCCHHHHH
QEV
HCC
>Mature Secondary Structure
MQINLKGKKAFIAGVGDDQGFGWAIAKALAEAGAEIIIGTWTPILKIFTSSLQAGKFDAS
CEEECCCCEEEEEECCCCCCCHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHCCCCCCHH
RRLPNGSLLTFAKIYPLDASFDKPEDVPEEIRENKRYKGVGGYTISEVCEAIGKDFGKID
HCCCCCCEEEEEEEEECCCCCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCHH
IFVHSLANAPEVQKPLLETSRKGYLAALSSSSYSFVSLLSHLGPYLNSQGSALTLTYLAS
HHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEC
EKIIPGYGGGMSSAKAALESDTRTLAWEAGRKWNIRVNTISAGPLRSRAARAIGFIDRMI
CCCCCCCCCCHHHHHHHHHCCCCEEEECCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHH
NYSQVNAPLQEELKACEVANVAAFLGSDLACAITGSTIYVDYGLHAMGVGMDSPTLKEAE
HHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEEEECCEEEECCCCCCCHHHHH
QEV
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8391534; 11759840 [H]