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The map label for this gene is hlyE [C]

Identifier: 46446759

GI number: 46446759

Start: 1349586

End: 1350170

Strand: Reverse

Name: hlyE [C]

Synonym: pc1125

Alternate gene names: 46446759

Gene position: 1350170-1349586 (Counterclockwise)

Preceding gene: 46446760

Following gene: 46446757

Centisome position: 55.92

GC content: 32.99

Gene sequence:

>585_bases
TTGACCCATGGACTGGGCTTAATGTTAAGTTTATTTGGCTTAATTTTCCTAATGATAAAGTCATTTTCAATGGAAGATTA
TTGGAAAGCTTTAAACTTTTTGATTTACGGATCTACATTAGTTCTACTTTATTCAGCTTCTACTCTTTATCATTTTTTTA
AAGATCCTTCTTTAAAAAAATTATTTAGAAAAGTCGATCATTGTGCAATTTATTTACTTATTGCCGGATCTTATACGCCT
TTTACACTAATAGCCTTACAGGGGTTTTGGGGATGGCTATTATTTAGTATTGTTTGGATTTTAGCCTGCTTTGGTGTCAT
TACTAAAGCTTTTTTTATTCAGCGATTTAAGACAGCCTCAACCTGGCTTTATCTTGGAATGGGATGGTTAATCATCATTG
CTTTTGAGCCATTATTCAATTCCGTCTCCTCCGAAGGTTTATATTGGCTTTTTATTGGAGGAGGATTTTATACGGTCGGA
GTCATTTTTTATGTATTAGACCGTATTCGCTTTTTTCATGCCATTTGGCATCTTTTTGTGATGGGAGGAAGTATATGCCA
TTTTTTTGCAATTTTATTTCTCTAA

Upstream 100 bases:

>100_bases
TAAATTGAAGAGATTAATGAAACAAAGTGAACAAACCATTGAAAACGAAGATTATTTATGGGCTCAAGGACTTATTCTCA
AAGATGAATGGGCGAATTAT

Downstream 100 bases:

>100_bases
AAATTTAAGCTTAGTTTTTTAACCATTATTTTAAATGTAAATAATTTCTTCTTCACAGAAAGCTTTTTTGTGTTTCAATA
TGTATTTAAAAGCTTGACTT

Product: hemolysin III

Products: NA

Alternate protein names: Hemolysin III; Hly-III [H]

Number of amino acids: Translated: 194; Mature: 193

Protein sequence:

>194_residues
MTHGLGLMLSLFGLIFLMIKSFSMEDYWKALNFLIYGSTLVLLYSASTLYHFFKDPSLKKLFRKVDHCAIYLLIAGSYTP
FTLIALQGFWGWLLFSIVWILACFGVITKAFFIQRFKTASTWLYLGMGWLIIIAFEPLFNSVSSEGLYWLFIGGGFYTVG
VIFYVLDRIRFFHAIWHLFVMGGSICHFFAILFL

Sequences:

>Translated_194_residues
MTHGLGLMLSLFGLIFLMIKSFSMEDYWKALNFLIYGSTLVLLYSASTLYHFFKDPSLKKLFRKVDHCAIYLLIAGSYTP
FTLIALQGFWGWLLFSIVWILACFGVITKAFFIQRFKTASTWLYLGMGWLIIIAFEPLFNSVSSEGLYWLFIGGGFYTVG
VIFYVLDRIRFFHAIWHLFVMGGSICHFFAILFL
>Mature_193_residues
THGLGLMLSLFGLIFLMIKSFSMEDYWKALNFLIYGSTLVLLYSASTLYHFFKDPSLKKLFRKVDHCAIYLLIAGSYTPF
TLIALQGFWGWLLFSIVWILACFGVITKAFFIQRFKTASTWLYLGMGWLIIIAFEPLFNSVSSEGLYWLFIGGGFYTVGV
IFYVLDRIRFFHAIWHLFVMGGSICHFFAILFL

Specific function: Unknown

COG id: COG1272

COG function: function code R; Predicted membrane protein, hemolysin III homolog

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0073 (Hly-III) family [H]

Homologues:

Organism=Homo sapiens, GI154759275, Length=198, Percent_Identity=34.8484848484849, Blast_Score=90, Evalue=1e-18,
Organism=Homo sapiens, GI154759277, Length=219, Percent_Identity=31.5068493150685, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI52630445, Length=198, Percent_Identity=30.8080808080808, Blast_Score=76, Evalue=2e-14,
Organism=Escherichia coli, GI1789266, Length=192, Percent_Identity=41.6666666666667, Blast_Score=154, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI71996356, Length=203, Percent_Identity=35.4679802955665, Blast_Score=116, Evalue=7e-27,
Organism=Drosophila melanogaster, GI24640324, Length=217, Percent_Identity=31.7972350230415, Blast_Score=88, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004254
- InterPro:   IPR005744 [H]

Pfam domain/function: PF03006 HlyIII [H]

EC number: NA

Molecular weight: Translated: 22443; Mature: 22312

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHGLGLMLSLFGLIFLMIKSFSMEDYWKALNFLIYGSTLVLLYSASTLYHFFKDPSLKK
CCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LFRKVDHCAIYLLIAGSYTPFTLIALQGFWGWLLFSIVWILACFGVITKAFFIQRFKTAS
HHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TWLYLGMGWLIIIAFEPLFNSVSSEGLYWLFIGGGFYTVGVIFYVLDRIRFFHAIWHLFV
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
MGGSICHFFAILFL
HCCHHHHHHHHHHC
>Mature Secondary Structure 
THGLGLMLSLFGLIFLMIKSFSMEDYWKALNFLIYGSTLVLLYSASTLYHFFKDPSLKK
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LFRKVDHCAIYLLIAGSYTPFTLIALQGFWGWLLFSIVWILACFGVITKAFFIQRFKTAS
HHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TWLYLGMGWLIIIAFEPLFNSVSSEGLYWLFIGGGFYTVGVIFYVLDRIRFFHAIWHLFV
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
MGGSICHFFAILFL
HCCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7495855 [H]