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The map label for this gene is cynT [H]

Identifier: 46446692

GI number: 46446692

Start: 1260664

End: 1261449

Strand: Reverse

Name: cynT [H]

Synonym: pc1058

Alternate gene names: 46446692

Gene position: 1261449-1260664 (Counterclockwise)

Preceding gene: 46446696

Following gene: 46446686

Centisome position: 52.25

GC content: 33.46

Gene sequence:

>786_bases
ATGAAACTTCAGCTATTTTTATTTGCAACTATTTTGAATATTTTGCCGCTAGTTTATGTGTCCGCAACTGAAGAAAAAAA
GCCTGCCAATAGTGAAATACCACAAACCCAAGATCTGGTTAATCAAGTCCTTACATTTGCAAGAAATCATCAAGACTTTA
AAAATCTTTATTTTAAAGAACATGAGCATGAATTTATTCGTTTAGCTGAACAAGGGCAAAATCCCCATACGTTATTTATT
GGTTGTAGCGATTCTCGCATGGTACCAGATTTGATTTTAGGGACAAAGCCTGGAGAATTATTTGTTATTCGTACGGCAGG
AAATTTTGTGCCTCCTTATGATCAAAATGGTTGGGATGGTGTTTCTGCCACTATTCAATATGCTCTTGAAGCTTTAGATG
TTAAGCATATCATTATTTGTGGTCATTCGCATTGTGGAGCTATTAAAGGTTTATTTCAGACAATTAATTCAACTCAGCTT
GGTATTTTAAAGCGATGGCTTCAATTTGGTAATGAAGCTAAAGAGACTACAATGAAAATTGTTAAACCGGAAACGTCTGA
AAAAGATTTGTATACTGTTGCAGAACAAATTTCAGTTGTGTATCAACTAGCACATCTTATGACATTTCCCGCTATTAAGA
AAAAAGTAGATGAAAAAACTTTAGACTTGCATGGTTGGTATTACAAAATAGAAACAGGAGAAGTTTCATATTATGACCCA
GAAACTTTTGTTTTCAAACCTTTAAAAAAGTTAAAAGCTCAAGCCCTTCAGTCAATATTGAATTAA

Upstream 100 bases:

>100_bases
GTTGAATAGCATAAATTTAGTTCGAATTTGTTTTGAATAGATAGCAATAAGTATAAGATGATGACTATCAAATTTTATTA
TCCCCAAACAGAGGAAAGGT

Downstream 100 bases:

>100_bases
TTTCATTTTATCAAAAAAAACTCTGTTTAGATTCAATTAAATCTAAACGGAGTTATATTTGAATAATTAAAGTTAGGAGA
TGACTTAGCTTTTATTCTTC

Product: putative carbonate dehydratase, cynT

Products: NA

Alternate protein names: Carbonate dehydratase 1 [H]

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MKLQLFLFATILNILPLVYVSATEEKKPANSEIPQTQDLVNQVLTFARNHQDFKNLYFKEHEHEFIRLAEQGQNPHTLFI
GCSDSRMVPDLILGTKPGELFVIRTAGNFVPPYDQNGWDGVSATIQYALEALDVKHIIICGHSHCGAIKGLFQTINSTQL
GILKRWLQFGNEAKETTMKIVKPETSEKDLYTVAEQISVVYQLAHLMTFPAIKKKVDEKTLDLHGWYYKIETGEVSYYDP
ETFVFKPLKKLKAQALQSILN

Sequences:

>Translated_261_residues
MKLQLFLFATILNILPLVYVSATEEKKPANSEIPQTQDLVNQVLTFARNHQDFKNLYFKEHEHEFIRLAEQGQNPHTLFI
GCSDSRMVPDLILGTKPGELFVIRTAGNFVPPYDQNGWDGVSATIQYALEALDVKHIIICGHSHCGAIKGLFQTINSTQL
GILKRWLQFGNEAKETTMKIVKPETSEKDLYTVAEQISVVYQLAHLMTFPAIKKKVDEKTLDLHGWYYKIETGEVSYYDP
ETFVFKPLKKLKAQALQSILN
>Mature_261_residues
MKLQLFLFATILNILPLVYVSATEEKKPANSEIPQTQDLVNQVLTFARNHQDFKNLYFKEHEHEFIRLAEQGQNPHTLFI
GCSDSRMVPDLILGTKPGELFVIRTAGNFVPPYDQNGWDGVSATIQYALEALDVKHIIICGHSHCGAIKGLFQTINSTQL
GILKRWLQFGNEAKETTMKIVKPETSEKDLYTVAEQISVVYQLAHLMTFPAIKKKVDEKTLDLHGWYYKIETGEVSYYDP
ETFVFKPLKKLKAQALQSILN

Specific function: Reversible hydration of carbon dioxide. Carbon dioxide formed in the bicarbonate-dependent decomposition of cyanate by cyanase (CynS) diffuses out of the cell faster than it would be hydrated to bicarbonate, so the apparent function of this enzyme is to c

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786534, Length=199, Percent_Identity=40.2010050251256, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1786318, Length=191, Percent_Identity=32.4607329842932, Blast_Score=99, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI115532990, Length=222, Percent_Identity=26.5765765765766, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6324292, Length=202, Percent_Identity=26.7326732673267, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24645213, Length=231, Percent_Identity=24.2424242424242, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 29731; Mature: 29731

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1 ; PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLQLFLFATILNILPLVYVSATEEKKPANSEIPQTQDLVNQVLTFARNHQDFKNLYFKE
CEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHH
HEHEFIRLAEQGQNPHTLFIGCSDSRMVPDLILGTKPGELFVIRTAGNFVPPYDQNGWDG
HHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHCCCCCCCEEEEEECCCCCCCCCCCCCCH
VSATIQYALEALDVKHIIICGHSHCGAIKGLFQTINSTQLGILKRWLQFGNEAKETTMKI
HHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHE
VKPETSEKDLYTVAEQISVVYQLAHLMTFPAIKKKVDEKTLDLHGWYYKIETGEVSYYDP
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCEEEEEECCEEEEECC
ETFVFKPLKKLKAQALQSILN
CHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MKLQLFLFATILNILPLVYVSATEEKKPANSEIPQTQDLVNQVLTFARNHQDFKNLYFKE
CEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHH
HEHEFIRLAEQGQNPHTLFIGCSDSRMVPDLILGTKPGELFVIRTAGNFVPPYDQNGWDG
HHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHCCCCCCCEEEEEECCCCCCCCCCCCCCH
VSATIQYALEALDVKHIIICGHSHCGAIKGLFQTINSTQLGILKRWLQFGNEAKETTMKI
HHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHE
VKPETSEKDLYTVAEQISVVYQLAHLMTFPAIKKKVDEKTLDLHGWYYKIETGEVSYYDP
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCEEEEEECCEEEEECC
ETFVFKPLKKLKAQALQSILN
CHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]