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The map label for this gene is inlA [H]

Identifier: 46446666

GI number: 46446666

Start: 1220127

End: 1222331

Strand: Reverse

Name: inlA [H]

Synonym: pc1032

Alternate gene names: 46446666

Gene position: 1222331-1220127 (Counterclockwise)

Preceding gene: 46446667

Following gene: 46446665

Centisome position: 50.63

GC content: 40.05

Gene sequence:

>2205_bases
TTGAATATTTCTAATTTTGGGTTTAATCCTAGTCAACTTGTCCCTACAACGGCTCCTTCTTACTATCCTCAAGAGATTAG
TGATCCTCTTGTGGATGAAAACACTCCCTTAGACAATCCTTTGCCTAATCTAGAAGAAACCGGTGCCTCAACGATTCAAG
CTCCCGCTCTTTCACTTTCATCTGATGAAATTCAACTAAGCTTTCAAGAGGGAACTTCTCTGACTATTTCTCACTCTCAG
CTAGCTTTGTTAAGGGACAAATCGCCTTATTTTAAGAATCTGTGGTCGGGGCAATTTCAAGAAACCCTGCAACATCCTCT
CGCTTTAATACAAAAAGACTTTACGCTTTTGCTTAATTGTGTCATGGATGCTAAATTTAAAGTTCCTTTGGAAGAGATCA
CTTCTGCCATTCAACTAGCTGATTATTATGAACTAACAGAAGTGGTAACAAATTTAGAAGAACAGCTGATTGATGGATAC
AAATCACAAAGATTTGAACCCTTTAACTCCACTGAAGAAAGTTTAGTCAGATTAAAAGAGATTTTAAATTTTGCGCAGCA
ATGTCGATTAAACCCTTTGAAAAACTATTTAGAATTCACCGTTGTGAGCGCCTTATTAAACCAGACCTCTCAGTTAGAGA
AGTTTGAAAAAATTGTAAATCACTTCTCAAAGAAGATAGAAACACTTAATTTTTCAGAAAATGCCCGTTTAACCGATGCC
CATCTTTTAACATTAAAAAATTGTAAAAATTTAAAAATACTTCATTTTAAGAAATGTTGGGGTGTCACTGATGCAGGATT
AGCGCATTTGACACCCTTAACGACTTTGCAGTATCTAGATCTAAGCGATTGCGAGAAACTCACTGATGATGGATTAGCGC
ATTTGACACCTTTAACGGGCTTGCAGCATCTAGATCTAAGCTGGTGCAGCAGTCTTACCGATGCAGGATTAGCGCATTTA
ACACCCTTAACGGCTTTGCAGCATCTAAATCTAAACAGATGCGAGTATCTCAAAGATGCAGGATTGGCGCATTTGACACC
TTTAACGGGTTTGCAACATCTAAATCTAAATAGGTGCAAGGATCTCACCGATGCTGGATTATCCCATTTGAAACCCTTAA
CCGCTTTGCAGCATCTAAATCTAAGCGAGTGTTGGAAACTTACCGATGCTGGATTAGCCCATTTGACACCTTTAACGGCT
TTACAGCATTTAGATCTAAGCAGGTGTAACAGTCTTACCGATGCAGGATTAGCGCATTTAACACCCTTAACAGCTTTACA
GCATCTAGATTTAAGCGATTGTCAAAATTTCACCGATGCAGGATTAGCGCATTTGACATCTTTGACGGGTTTGCAGTATC
TAAATCTAAGCGAATATAAGAATCTCACTGATGCAGGTTTAGCCCATTTGACGCCCTTAACAGCTTTGCAGCATCTTAAT
CTGTGTAATTGTAGAAAATTCACGGATAATGGATTAGCGCATTTGACGCCCTTAACAGCTTTGCAACACCTAGATCTGAG
CCATTGTAAGAATCTCACTGATGATGGATTAGCCCATTTAGCACCTTTAACGGGCTTGCAGCGTCTAGTTCTAAGTTGGT
GCGATAAGCTCACCGATGCAGGATTAGCCCATTTGACACCCCTAACGGCTTTGCAGTATTTAGATCTGAGCTGCTGTGAG
ATCACCGATGCAGGATTAGCCCATTTGACACCTTTAACGGGCTTGCAGCATCTAGTTCTAGTCTATTGCTGGCAACTCAC
CGATGCAGGATTAGCCCATTTAACACCCTTAACGACTTTGCAATATCTATATCTAGGCAGTTGCAATAGACTCACCGATG
CAGGATTGGCCCATTTGGCACCTTTAACAGCTTTGCAGCATCTAGCTTTAAACGACTGTAGGAAACTTACCGATACAGGA
TTAGCGCATTTAACACCCTTAACGGCTTTGCAGCATTTAACTCTAAACAGATGCGAGAAACTCACTGATGATGGATTAGC
CCATTTGAAACCCTTAGCGGCTTTGCAGTATTTAGATCTGAGCTACTGTGAGATCACCGATGCTGGATTAGCCCATTTAA
CACATTTAATGGCTTTACAACGTTTAGATCTATATGGGCGTGAGATCACTGATGATGGATTAGAACGTTTTGAAACTTTA
GCAGCTTCATTTAATTTAGAAATAAGGCTGGATAGATTTCTATAA

Upstream 100 bases:

>100_bases
CCTATTTTAACTTATTAATATTGCAATAATTTTTATCTATTCATCATATTGTTAAAATAGCTATAAATGAAAATTTATTT
TATTCATTGGGATGGTCATT

Downstream 100 bases:

>100_bases
AGAAGGAAACTAGGTCCAAAAATAAAAGAGTACTTTGTCCTAAGAGGATCAAGGATAAAATTTCATTAAAGTTGATCAAT
TTTCATTGAGACGTTTCTCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 734; Mature: 734

Protein sequence:

>734_residues
MNISNFGFNPSQLVPTTAPSYYPQEISDPLVDENTPLDNPLPNLEETGASTIQAPALSLSSDEIQLSFQEGTSLTISHSQ
LALLRDKSPYFKNLWSGQFQETLQHPLALIQKDFTLLLNCVMDAKFKVPLEEITSAIQLADYYELTEVVTNLEEQLIDGY
KSQRFEPFNSTEESLVRLKEILNFAQQCRLNPLKNYLEFTVVSALLNQTSQLEKFEKIVNHFSKKIETLNFSENARLTDA
HLLTLKNCKNLKILHFKKCWGVTDAGLAHLTPLTTLQYLDLSDCEKLTDDGLAHLTPLTGLQHLDLSWCSSLTDAGLAHL
TPLTALQHLNLNRCEYLKDAGLAHLTPLTGLQHLNLNRCKDLTDAGLSHLKPLTALQHLNLSECWKLTDAGLAHLTPLTA
LQHLDLSRCNSLTDAGLAHLTPLTALQHLDLSDCQNFTDAGLAHLTSLTGLQYLNLSEYKNLTDAGLAHLTPLTALQHLN
LCNCRKFTDNGLAHLTPLTALQHLDLSHCKNLTDDGLAHLAPLTGLQRLVLSWCDKLTDAGLAHLTPLTALQYLDLSCCE
ITDAGLAHLTPLTGLQHLVLVYCWQLTDAGLAHLTPLTTLQYLYLGSCNRLTDAGLAHLAPLTALQHLALNDCRKLTDTG
LAHLTPLTALQHLTLNRCEKLTDDGLAHLKPLAALQYLDLSYCEITDAGLAHLTHLMALQRLDLYGREITDDGLERFETL
AASFNLEIRLDRFL

Sequences:

>Translated_734_residues
MNISNFGFNPSQLVPTTAPSYYPQEISDPLVDENTPLDNPLPNLEETGASTIQAPALSLSSDEIQLSFQEGTSLTISHSQ
LALLRDKSPYFKNLWSGQFQETLQHPLALIQKDFTLLLNCVMDAKFKVPLEEITSAIQLADYYELTEVVTNLEEQLIDGY
KSQRFEPFNSTEESLVRLKEILNFAQQCRLNPLKNYLEFTVVSALLNQTSQLEKFEKIVNHFSKKIETLNFSENARLTDA
HLLTLKNCKNLKILHFKKCWGVTDAGLAHLTPLTTLQYLDLSDCEKLTDDGLAHLTPLTGLQHLDLSWCSSLTDAGLAHL
TPLTALQHLNLNRCEYLKDAGLAHLTPLTGLQHLNLNRCKDLTDAGLSHLKPLTALQHLNLSECWKLTDAGLAHLTPLTA
LQHLDLSRCNSLTDAGLAHLTPLTALQHLDLSDCQNFTDAGLAHLTSLTGLQYLNLSEYKNLTDAGLAHLTPLTALQHLN
LCNCRKFTDNGLAHLTPLTALQHLDLSHCKNLTDDGLAHLAPLTGLQRLVLSWCDKLTDAGLAHLTPLTALQYLDLSCCE
ITDAGLAHLTPLTGLQHLVLVYCWQLTDAGLAHLTPLTTLQYLYLGSCNRLTDAGLAHLAPLTALQHLALNDCRKLTDTG
LAHLTPLTALQHLTLNRCEKLTDDGLAHLKPLAALQYLDLSYCEITDAGLAHLTHLMALQRLDLYGREITDDGLERFETL
AASFNLEIRLDRFL
>Mature_734_residues
MNISNFGFNPSQLVPTTAPSYYPQEISDPLVDENTPLDNPLPNLEETGASTIQAPALSLSSDEIQLSFQEGTSLTISHSQ
LALLRDKSPYFKNLWSGQFQETLQHPLALIQKDFTLLLNCVMDAKFKVPLEEITSAIQLADYYELTEVVTNLEEQLIDGY
KSQRFEPFNSTEESLVRLKEILNFAQQCRLNPLKNYLEFTVVSALLNQTSQLEKFEKIVNHFSKKIETLNFSENARLTDA
HLLTLKNCKNLKILHFKKCWGVTDAGLAHLTPLTTLQYLDLSDCEKLTDDGLAHLTPLTGLQHLDLSWCSSLTDAGLAHL
TPLTALQHLNLNRCEYLKDAGLAHLTPLTGLQHLNLNRCKDLTDAGLSHLKPLTALQHLNLSECWKLTDAGLAHLTPLTA
LQHLDLSRCNSLTDAGLAHLTPLTALQHLDLSDCQNFTDAGLAHLTSLTGLQYLNLSEYKNLTDAGLAHLTPLTALQHLN
LCNCRKFTDNGLAHLTPLTALQHLDLSHCKNLTDDGLAHLAPLTGLQRLVLSWCDKLTDAGLAHLTPLTALQYLDLSCCE
ITDAGLAHLTPLTGLQHLVLVYCWQLTDAGLAHLTPLTTLQYLYLGSCNRLTDAGLAHLAPLTALQHLALNDCRKLTDTG
LAHLTPLTALQHLTLNRCEKLTDDGLAHLKPLAALQYLDLSYCEITDAGLAHLTHLMALQRLDLYGREITDDGLERFETL
AASFNLEIRLDRFL

Specific function: Mediates the entry of Listeria monocytogenes into cells [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 14 LRR (leucine-rich) repeats [H]

Homologues:

Organism=Homo sapiens, GI22748931, Length=343, Percent_Identity=33.2361516034985, Blast_Score=153, Evalue=6e-37,
Organism=Homo sapiens, GI161333852, Length=457, Percent_Identity=27.5711159737418, Blast_Score=124, Evalue=3e-28,
Organism=Homo sapiens, GI284447308, Length=335, Percent_Identity=32.2388059701493, Blast_Score=122, Evalue=9e-28,
Organism=Homo sapiens, GI27734755, Length=398, Percent_Identity=28.894472361809, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI161333854, Length=332, Percent_Identity=30.1204819277108, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI296531375, Length=371, Percent_Identity=28.5714285714286, Blast_Score=106, Evalue=1e-22,
Organism=Homo sapiens, GI6912466, Length=280, Percent_Identity=31.0714285714286, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI289666746, Length=285, Percent_Identity=35.4385964912281, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI284447314, Length=344, Percent_Identity=29.3604651162791, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI16306588, Length=435, Percent_Identity=27.3563218390805, Blast_Score=67, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI25151694, Length=307, Percent_Identity=31.2703583061889, Blast_Score=109, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI25151696, Length=307, Percent_Identity=31.2703583061889, Blast_Score=109, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6322549, Length=322, Percent_Identity=26.3975155279503, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI17647819, Length=300, Percent_Identity=36.3333333333333, Blast_Score=139, Evalue=9e-33,
Organism=Drosophila melanogaster, GI24662818, Length=329, Percent_Identity=32.8267477203647, Blast_Score=105, Evalue=8e-23,
Organism=Drosophila melanogaster, GI161076545, Length=392, Percent_Identity=29.3367346938776, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24652783, Length=392, Percent_Identity=29.3367346938776, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI161076547, Length=392, Percent_Identity=29.3367346938776, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI161076549, Length=392, Percent_Identity=29.3367346938776, Blast_Score=100, Evalue=5e-21,
Organism=Drosophila melanogaster, GI21357913, Length=266, Percent_Identity=31.9548872180451, Blast_Score=95, Evalue=2e-19,
Organism=Drosophila melanogaster, GI19921840, Length=408, Percent_Identity=26.2254901960784, Blast_Score=72, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014755
- InterPro:   IPR019948
- InterPro:   IPR014756
- InterPro:   IPR001611
- InterPro:   IPR013378
- InterPro:   IPR019931
- InterPro:   IPR012569
- InterPro:   IPR001899 [H]

Pfam domain/function: PF09479 Flg_new; PF00746 Gram_pos_anchor; PF00560 LRR_1; PF08191 LRR_adjacent [H]

EC number: NA

Molecular weight: Translated: 81338; Mature: 81338

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNISNFGFNPSQLVPTTAPSYYPQEISDPLVDENTPLDNPLPNLEETGASTIQAPALSLS
CCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCC
SDEIQLSFQEGTSLTISHSQLALLRDKSPYFKNLWSGQFQETLQHPLALIQKDFTLLLNC
CCCEEEEECCCCEEEEECHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
VMDAKFKVPLEEITSAIQLADYYELTEVVTNLEEQLIDGYKSQRFEPFNSTEESLVRLKE
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
ILNFAQQCRLNPLKNYLEFTVVSALLNQTSQLEKFEKIVNHFSKKIETLNFSENARLTDA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
HLLTLKNCKNLKILHFKKCWGVTDAGLAHLTPLTTLQYLDLSDCEKLTDDGLAHLTPLTG
HEEEECCCCCCEEEEEHHHCCCCCCCHHHHCHHHHHHHCCHHHHHHHHCCCHHHHHHHCC
LQHLDLSWCSSLTDAGLAHLTPLTALQHLNLNRCEYLKDAGLAHLTPLTGLQHLNLNRCK
CHHCCHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHCCCHHCCHHHCCCCCCHHHHH
DLTDAGLSHLKPLTALQHLNLSECWKLTDAGLAHLTPLTALQHLDLSRCNSLTDAGLAHL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHCCHHHHCCHHHCCHHHH
TPLTALQHLDLSDCQNFTDAGLAHLTSLTGLQYLNLSEYKNLTDAGLAHLTPLTALQHLN
HHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHCC
LCNCRKFTDNGLAHLTPLTALQHLDLSHCKNLTDDGLAHLAPLTGLQRLVLSWCDKLTDA
HHHCCCCCCCCCHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
GLAHLTPLTALQYLDLSCCEITDAGLAHLTPLTGLQHLVLVYCWQLTDAGLAHLTPLTTL
CHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
QYLYLGSCNRLTDAGLAHLAPLTALQHLALNDCRKLTDTGLAHLTPLTALQHLTLNRCEK
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
LTDDGLAHLKPLAALQYLDLSYCEITDAGLAHLTHLMALQRLDLYGREITDDGLERFETL
HCCCCHHHHHHHHHHHHHCCHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
AASFNLEIRLDRFL
HHHCCEEEEECCCC
>Mature Secondary Structure
MNISNFGFNPSQLVPTTAPSYYPQEISDPLVDENTPLDNPLPNLEETGASTIQAPALSLS
CCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCC
SDEIQLSFQEGTSLTISHSQLALLRDKSPYFKNLWSGQFQETLQHPLALIQKDFTLLLNC
CCCEEEEECCCCEEEEECHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
VMDAKFKVPLEEITSAIQLADYYELTEVVTNLEEQLIDGYKSQRFEPFNSTEESLVRLKE
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
ILNFAQQCRLNPLKNYLEFTVVSALLNQTSQLEKFEKIVNHFSKKIETLNFSENARLTDA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
HLLTLKNCKNLKILHFKKCWGVTDAGLAHLTPLTTLQYLDLSDCEKLTDDGLAHLTPLTG
HEEEECCCCCCEEEEEHHHCCCCCCCHHHHCHHHHHHHCCHHHHHHHHCCCHHHHHHHCC
LQHLDLSWCSSLTDAGLAHLTPLTALQHLNLNRCEYLKDAGLAHLTPLTGLQHLNLNRCK
CHHCCHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHCCCHHCCHHHCCCCCCHHHHH
DLTDAGLSHLKPLTALQHLNLSECWKLTDAGLAHLTPLTALQHLDLSRCNSLTDAGLAHL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHCCHHHHCCHHHCCHHHH
TPLTALQHLDLSDCQNFTDAGLAHLTSLTGLQYLNLSEYKNLTDAGLAHLTPLTALQHLN
HHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHCC
LCNCRKFTDNGLAHLTPLTALQHLDLSHCKNLTDDGLAHLAPLTGLQRLVLSWCDKLTDA
HHHCCCCCCCCCHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
GLAHLTPLTALQYLDLSCCEITDAGLAHLTPLTGLQHLVLVYCWQLTDAGLAHLTPLTTL
CHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
QYLYLGSCNRLTDAGLAHLAPLTALQHLALNDCRKLTDTGLAHLTPLTALQHLTLNRCEK
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
LTDDGLAHLKPLAALQYLDLSYCEITDAGLAHLTHLMALQRLDLYGREITDDGLERFETL
HCCCCHHHHHHHHHHHHHCCHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
AASFNLEIRLDRFL
HHHCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9541569 [H]