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The map label for this gene is nfi [H]

Identifier: 46446491

GI number: 46446491

Start: 1038389

End: 1038634

Strand: Direct

Name: nfi [H]

Synonym: pc0857

Alternate gene names: 46446491

Gene position: 1038389-1038634 (Clockwise)

Preceding gene: 46446490

Following gene: 46446492

Centisome position: 43.01

GC content: 42.28

Gene sequence:

>246_bases
GTGGCAAACTACAAGCTCGTCATAAACCTATGCATAAAACAACTCGACATGGCTTTTCCCTCATTTACAGAGGAAGCAAA
AAAAATACAGAAGGTCATGGCCGAAAAGGTGGTTGTAGAAGATCCTTTTCAGGAGCCTCAGTGGATCGGTGGTATGGATG
TCAGTAATAACCTCTATGATCCTAGCCAACTCATTTATGCAACAATTGTCGTGCTTAAATTCCCCGAGTTTCAGTTAGTG
GAGTAG

Upstream 100 bases:

>100_bases
AGAGCCAGCAATTAATGCGTGTTATGCGAGAGGATGCTGATCATTATCGCTACGAGAACTTAGGATCTGTACAATTTGTA
CCGCTCGTTGGAAAAGAAGG

Downstream 100 bases:

>100_bases
GAGGGAGTTATAGAAGAGCAGACTCCTCCTTATATCCTAGGTTTATTAGGGTTTCGAGAAGCGCCCTCTCTTGTTCATGC
ATTTGAGCGCCTGCAAAGGC

Product: hypothetical protein

Products: NA

Alternate protein names: Deoxyinosine 3'endonuclease; Deoxyribonuclease V; DNase V [H]

Number of amino acids: Translated: 81; Mature: 80

Protein sequence:

>81_residues
MANYKLVINLCIKQLDMAFPSFTEEAKKIQKVMAEKVVVEDPFQEPQWIGGMDVSNNLYDPSQLIYATIVVLKFPEFQLV
E

Sequences:

>Translated_81_residues
MANYKLVINLCIKQLDMAFPSFTEEAKKIQKVMAEKVVVEDPFQEPQWIGGMDVSNNLYDPSQLIYATIVVLKFPEFQLV
E
>Mature_80_residues
ANYKLVINLCIKQLDMAFPSFTEEAKKIQKVMAEKVVVEDPFQEPQWIGGMDVSNNLYDPSQLIYATIVVLKFPEFQLVE

Specific function: Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the endonuclease V family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007581 [H]

Pfam domain/function: PF04493 Endonuclease_5 [H]

EC number: =3.1.21.7 [H]

Molecular weight: Translated: 9326; Mature: 9195

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANYKLVINLCIKQLDMAFPSFTEEAKKIQKVMAEKVVVEDPFQEPQWIGGMDVSNNLYD
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
PSQLIYATIVVLKFPEFQLVE
HHHHHHHHHHHHCCCCEEECC
>Mature Secondary Structure 
ANYKLVINLCIKQLDMAFPSFTEEAKKIQKVMAEKVVVEDPFQEPQWIGGMDVSNNLYD
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
PSQLIYATIVVLKFPEFQLVE
HHHHHHHHHHHHCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA