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The map label for this gene is kynB [H]

Identifier: 46446469

GI number: 46446469

Start: 1018312

End: 1019460

Strand: Direct

Name: kynB [H]

Synonym: pc0835

Alternate gene names: 46446469

Gene position: 1018312-1019460 (Clockwise)

Preceding gene: 46446468

Following gene: 46446470

Centisome position: 42.18

GC content: 35.51

Gene sequence:

>1149_bases
ATGAAAAATTCTAAAACATTGATTACTTTACTAAGTTCCTTTGAGGCTAAACAAGCTTATCATGAAATGTTAGGGTTCTT
GCCCGAGCTTTTTGGCAATTCTAAAACCGAAGAGAAAGAGCAAAGTGTTACTAAAGAAAAATGTTTTTTCGGATACTTTA
TAGATAGAATTTGTTTAGGAATACTTGCTCTTGAATTTCCGTTTGTTCAGACAGCGCATATTGATTGGATAAGGGTTAAA
GAAAACTCGCCGACACAAGAAATCGAAAAGGCTTTACTTTGTCATGCAGAAATGTTTTGCCAAGAACATTCTATTTATTC
TTTGACCGCAGAAACACGAATTCCATTAAAAAATGAACATTTAAAAGGATTTGAATTTTATATTAAAGCTGGTTTTAGAC
CTTTGTTTGAGCGTAGAAACGCTGATCTTGGCTATGTAATCGTTTATTTAAATAAAATCATCTCTCCAAAAATATTTAAG
TGGGTTGATTTGACACATGAACTTTCTGAAAAGATTCCCACTTGGGATAGAAACTGTGGATTTAAACACAAAGAAATTTC
GACATATGAAGAGGGGACAACTGACTGTCAGTTTTCGATTCAAAGCATTGAAATGTTGGCGGGTGCTGGAACACATATAG
ATGCTCCAGCGCATTGTTATCCCCACAGTAAAACAGTTATAGATCTGCCATTACAATCTTTAATTTCTCCCTGTGTTGTG
ATAGATGTGTCTGAAGAAGCTCATGACCGCTATTCGGTTGATATTCTAACTATAAGAAATTTTGAAAGGAAATATGGAAA
TATTTGTAAAAATACTTTCGTTATTTTTTATACGGGTTGGGAGCGATTTTGGAAGCAACCTGAAAAATATCATAATCATT
TCGATTTTCCCTCCGTCACCCAGGAAGTAGCTGAATATCTCGTATCTAAAGATATTCGAGGTATTGGCATTGACACCCTT
TCTCCTGACAGACCAGATAGCAAATTTCCAGTTCATCAGATAATTTTAGGGGCAGGTAAATACATTGTTGAAAATGTTGC
CAAGGCAAATTTATTACCTGCTGTTGGAAGTTACGTTTTTGTCATGCCCATACCCATAGTGAAGGGGACTGAAGCTCCTA
TTCGTCTTTTAGGAATGTTTCCTGGATGA

Upstream 100 bases:

>100_bases
AAATTAAGGGAAATCTTGATCCAATGAATTTTTTTAATTTAGCAATAAGTATTCTAAAAACTTATTCCAGTCTATTTGAT
GACGTTAACTTAGGAAATTA

Downstream 100 bases:

>100_bases
CAAATATGTTTTTTCTTTTTAAGATCGTTACATCAATGTTAGAAAAATTAAATGAATGCAAAGAAAGTACCAGAGGTCAA
ATGCCTTAAATGAATTGAGA

Product: hypothetical protein

Products: NA

Alternate protein names: KFA; N-formylkynurenine formamidase [H]

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MKNSKTLITLLSSFEAKQAYHEMLGFLPELFGNSKTEEKEQSVTKEKCFFGYFIDRICLGILALEFPFVQTAHIDWIRVK
ENSPTQEIEKALLCHAEMFCQEHSIYSLTAETRIPLKNEHLKGFEFYIKAGFRPLFERRNADLGYVIVYLNKIISPKIFK
WVDLTHELSEKIPTWDRNCGFKHKEISTYEEGTTDCQFSIQSIEMLAGAGTHIDAPAHCYPHSKTVIDLPLQSLISPCVV
IDVSEEAHDRYSVDILTIRNFERKYGNICKNTFVIFYTGWERFWKQPEKYHNHFDFPSVTQEVAEYLVSKDIRGIGIDTL
SPDRPDSKFPVHQIILGAGKYIVENVAKANLLPAVGSYVFVMPIPIVKGTEAPIRLLGMFPG

Sequences:

>Translated_382_residues
MKNSKTLITLLSSFEAKQAYHEMLGFLPELFGNSKTEEKEQSVTKEKCFFGYFIDRICLGILALEFPFVQTAHIDWIRVK
ENSPTQEIEKALLCHAEMFCQEHSIYSLTAETRIPLKNEHLKGFEFYIKAGFRPLFERRNADLGYVIVYLNKIISPKIFK
WVDLTHELSEKIPTWDRNCGFKHKEISTYEEGTTDCQFSIQSIEMLAGAGTHIDAPAHCYPHSKTVIDLPLQSLISPCVV
IDVSEEAHDRYSVDILTIRNFERKYGNICKNTFVIFYTGWERFWKQPEKYHNHFDFPSVTQEVAEYLVSKDIRGIGIDTL
SPDRPDSKFPVHQIILGAGKYIVENVAKANLLPAVGSYVFVMPIPIVKGTEAPIRLLGMFPG
>Mature_382_residues
MKNSKTLITLLSSFEAKQAYHEMLGFLPELFGNSKTEEKEQSVTKEKCFFGYFIDRICLGILALEFPFVQTAHIDWIRVK
ENSPTQEIEKALLCHAEMFCQEHSIYSLTAETRIPLKNEHLKGFEFYIKAGFRPLFERRNADLGYVIVYLNKIISPKIFK
WVDLTHELSEKIPTWDRNCGFKHKEISTYEEGTTDCQFSIQSIEMLAGAGTHIDAPAHCYPHSKTVIDLPLQSLISPCVV
IDVSEEAHDRYSVDILTIRNFERKYGNICKNTFVIFYTGWERFWKQPEKYHNHFDFPSVTQEVAEYLVSKDIRGIGIDTL
SPDRPDSKFPVHQIILGAGKYIVENVAKANLLPAVGSYVFVMPIPIVKGTEAPIRLLGMFPG

Specific function: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine [H]

COG id: COG1878

COG function: function code R; Predicted metal-dependent hydrolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kynB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017484
- InterPro:   IPR007325 [H]

Pfam domain/function: PF04199 Cyclase [H]

EC number: =3.5.1.9 [H]

Molecular weight: Translated: 43788; Mature: 43788

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNSKTLITLLSSFEAKQAYHEMLGFLPELFGNSKTEEKEQSVTKEKCFFGYFIDRICLG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ILALEFPFVQTAHIDWIRVKENSPTQEIEKALLCHAEMFCQEHSIYSLTAETRIPLKNEH
HHHHHCCCEEEECCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCC
LKGFEFYIKAGFRPLFERRNADLGYVIVYLNKIISPKIFKWVDLTHELSEKIPTWDRNCG
CCCCEEEEHHCCHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCC
FKHKEISTYEEGTTDCQFSIQSIEMLAGAGTHIDAPAHCYPHSKTVIDLPLQSLISPCVV
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCHHHHCCCEEE
IDVSEEAHDRYSVDILTIRNFERKYGNICKNTFVIFYTGWERFWKQPEKYHNHFDFPSVT
EECCHHCCCCEEEEEEEECCHHHHHHHHHCCCEEEEECCHHHHCCCHHHHCCCCCCHHHH
QEVAEYLVSKDIRGIGIDTLSPDRPDSKFPVHQIILGAGKYIVENVAKANLLPAVGSYVF
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCEEE
VMPIPIVKGTEAPIRLLGMFPG
EEECCCCCCCCCCEEEEECCCC
>Mature Secondary Structure
MKNSKTLITLLSSFEAKQAYHEMLGFLPELFGNSKTEEKEQSVTKEKCFFGYFIDRICLG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ILALEFPFVQTAHIDWIRVKENSPTQEIEKALLCHAEMFCQEHSIYSLTAETRIPLKNEH
HHHHHCCCEEEECCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCC
LKGFEFYIKAGFRPLFERRNADLGYVIVYLNKIISPKIFKWVDLTHELSEKIPTWDRNCG
CCCCEEEEHHCCHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCC
FKHKEISTYEEGTTDCQFSIQSIEMLAGAGTHIDAPAHCYPHSKTVIDLPLQSLISPCVV
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCHHHHCCCEEE
IDVSEEAHDRYSVDILTIRNFERKYGNICKNTFVIFYTGWERFWKQPEKYHNHFDFPSVT
EECCHHCCCCEEEEEEEECCHHHHHHHHHCCCEEEEECCHHHHCCCHHHHCCCCCCHHHH
QEVAEYLVSKDIRGIGIDTLSPDRPDSKFPVHQIILGAGKYIVENVAKANLLPAVGSYVF
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCEEE
VMPIPIVKGTEAPIRLLGMFPG
EEECCCCCCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA