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The map label for this gene is devB [H]

Identifier: 46446453

GI number: 46446453

Start: 1001027

End: 1001665

Strand: Reverse

Name: devB [H]

Synonym: pc0819

Alternate gene names: 46446453

Gene position: 1001665-1001027 (Counterclockwise)

Preceding gene: 46446454

Following gene: 46446452

Centisome position: 41.49

GC content: 38.5

Gene sequence:

>639_bases
TTGTTTACAGTGGCTTTATCAGGAGGACAAACCCCTAATGCTATTTTTAAAGAATTGAGTCAACAAGACTATTTAAAGCA
ATTGGACTGGACTAAAGTGTTCTGTTTTTGGAGTGATGAAAGGAGCGTTCCTCCGACAGATACGGAGAGCAATTATGCCA
TGGCTATGGAATCTGGCCTCGCTAAACTTCCTTTAAAAAGAGAACATATTTTTCGCATGAAAGCAGAAAGTGACATTGAA
GAGAACGCTCTCGAGTACGAAGCCATCATACGTGAAAAAGTCTCTTCTAATAGCTTTGATTTATTAATGCTAGGAATGGG
AGATGATGGTCATACAGCATCACTTTTTCCTCATACGCAAGGCTTACACGCAAAAGATCGTCTAGTCATTGCTAATTACG
TTCCCCAAAAACATACTTGGCGCATGTCTTTGACCTATGAATGTATTCATTTGGCTAAAACGATTTGTATTTACGCCATG
GGAAAGAAAAAAGCCAATATGGTTGCTCAAGCATTAACAAAAAGCTATGATCCAGATAACCTTCCCATCCAACGTATTGG
TACAACACATCATAAAGCTCTATGGATTTTAGATCATGAAGCTGGTGAAAAACTCTTGCAAATTTTCCAAAGACGGTAA

Upstream 100 bases:

>100_bases
AAGGCGTAATTTTATCGTTGTTGGAAATGCAGAAGAAACAATTCAATTTTGCGTAAAACAATTCATAGAAATTGCGCAAG
AGGCAATTGAAAAACGGGGT

Downstream 100 bases:

>100_bases
ACACTTAAGACAAAAATCCACAAAAATGAAATAGTTTAGACCTTATGTTAGTTTTGGGAATAGAAAGTACTTGTGATGAA
ACAGCGTGTGCCATCGTTCG

Product: putative 6-phosphogluconolactonase (6PGL).

Products: NA

Alternate protein names: 6PGL [H]

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MFTVALSGGQTPNAIFKELSQQDYLKQLDWTKVFCFWSDERSVPPTDTESNYAMAMESGLAKLPLKREHIFRMKAESDIE
ENALEYEAIIREKVSSNSFDLLMLGMGDDGHTASLFPHTQGLHAKDRLVIANYVPQKHTWRMSLTYECIHLAKTICIYAM
GKKKANMVAQALTKSYDPDNLPIQRIGTTHHKALWILDHEAGEKLLQIFQRR

Sequences:

>Translated_212_residues
MFTVALSGGQTPNAIFKELSQQDYLKQLDWTKVFCFWSDERSVPPTDTESNYAMAMESGLAKLPLKREHIFRMKAESDIE
ENALEYEAIIREKVSSNSFDLLMLGMGDDGHTASLFPHTQGLHAKDRLVIANYVPQKHTWRMSLTYECIHLAKTICIYAM
GKKKANMVAQALTKSYDPDNLPIQRIGTTHHKALWILDHEAGEKLLQIFQRR
>Mature_212_residues
MFTVALSGGQTPNAIFKELSQQDYLKQLDWTKVFCFWSDERSVPPTDTESNYAMAMESGLAKLPLKREHIFRMKAESDIE
ENALEYEAIIREKVSSNSFDLLMLGMGDDGHTASLFPHTQGLHAKDRLVIANYVPQKHTWRMSLTYECIHLAKTICIYAM
GKKKANMVAQALTKSYDPDNLPIQRIGTTHHKALWILDHEAGEKLLQIFQRR

Specific function: Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily [H]

Homologues:

Organism=Homo sapiens, GI52145310, Length=209, Percent_Identity=32.5358851674641, Blast_Score=106, Evalue=1e-23,
Organism=Homo sapiens, GI6912586, Length=218, Percent_Identity=30.2752293577982, Blast_Score=97, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI115533060, Length=178, Percent_Identity=29.7752808988764, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI115533058, Length=178, Percent_Identity=29.7752808988764, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6321957, Length=217, Percent_Identity=31.7972350230415, Blast_Score=89, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6321687, Length=216, Percent_Identity=30.0925925925926, Blast_Score=85, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6319918, Length=181, Percent_Identity=29.8342541436464, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324362, Length=180, Percent_Identity=30.5555555555556, Blast_Score=65, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24641119, Length=208, Percent_Identity=33.1730769230769, Blast_Score=90, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005900 [H]

Pfam domain/function: NA

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 24260; Mature: 24260

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTVALSGGQTPNAIFKELSQQDYLKQLDWTKVFCFWSDERSVPPTDTESNYAMAMESGL
CEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCHHHHHCCH
AKLPLKREHIFRMKAESDIEENALEYEAIIREKVSSNSFDLLMLGMGDDGHTASLFPHTQ
HHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEECCCCC
GLHAKDRLVIANYVPQKHTWRMSLTYECIHLAKTICIYAMGKKKANMVAQALTKSYDPDN
CCCCCCCEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCC
LPIQRIGTTHHKALWILDHEAGEKLLQIFQRR
CCHHHCCCCCCEEEEEEECHHHHHHHHHHHCC
>Mature Secondary Structure
MFTVALSGGQTPNAIFKELSQQDYLKQLDWTKVFCFWSDERSVPPTDTESNYAMAMESGL
CEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCHHHHHCCH
AKLPLKREHIFRMKAESDIEENALEYEAIIREKVSSNSFDLLMLGMGDDGHTASLFPHTQ
HHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEECCCCC
GLHAKDRLVIANYVPQKHTWRMSLTYECIHLAKTICIYAMGKKKANMVAQALTKSYDPDN
CCCCCCCEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCC
LPIQRIGTTHHKALWILDHEAGEKLLQIFQRR
CCHHHCCCCCCEEEEEEECHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]