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The map label for this gene is gcp

Identifier: 46446452

GI number: 46446452

Start: 999951

End: 1000982

Strand: Reverse

Name: gcp

Synonym: pc0818

Alternate gene names: 46446452

Gene position: 1000982-999951 (Counterclockwise)

Preceding gene: 46446453

Following gene: 46446451

Centisome position: 41.46

GC content: 37.98

Gene sequence:

>1032_bases
ATGTTAGTTTTGGGAATAGAAAGTACTTGTGATGAAACAGCGTGTGCCATCGTTCGTGATGGAAAAGATATTTTGTCAAA
CATTGTCGCTTCACAAATTGATTTACACAAAGAATACGGAGGCGTTGTTCCTGAACTGGCTTGTCGAAGGCATATTGATT
TAATTATTCCAGTCATTGATCAAGCTCTTAATCAAGCAAAATTAACACTTGAACAAATTGATTTAATTGCGGTTGCAAAT
GGCCCAGGGTTAATTGGAGCTTTACTGATTGGTTTAAATACTGCTAAAGCACTCGCTTTAGCCCTTCGAAAACCTTTTAT
TGGCATTAATCACGTGGAAGCTCATTTATATGCAGCAATTATGTCACACCCTCAAGATTTTCAATTTCCTTGTTTAGGCG
TCGTTCTGTCTGGCGGTCATACTGCTCTTGTTTTAATTAAACAAATTGGTCAATACGAACTTATCGGGCAAACTGTGGAT
GATGCAGTCGGAGAAGCTTTTGATAAAGTCGCTAAGATGCTTAATCTTCCCTATCCTGGTGGACCAGAAATAGAAAATTT
AGCAAGGCACGGCCGTTCTGTTAAATTTAATTTTAAAGCTGGACAAGTGAAAGGTCGCCCTTTGGATTTTTCTTTCAGCG
GACTAAAAACAGCAGTCCTTTATGCTATTAAAGATCCTAAAGCGCTTAAAGAGATGGTTCTTTTATCCTCCGAAATGACT
CAAGATATCGCAGCAAGTTTCCAAGAAGCCGCTTGCAGTGATATTGTGAAAAAATCTCTATTGGCTGCAAAACAATATGG
TGTCAATACTCTCTTATTTGGGGGGGGTGTAACGAATAATTGTTACTTAAGAAAATTATTTTCTGTGGCCAATTCAAACT
TAAACTATATATGGCCTTCTGCCGGTTTAAGTTTGGATAATGCTGCCATGATCGCAGGTCTTGGATACTACCGTTATCAA
TTACAAAACAAAAGTGATTCCATGGATTTAGAACCATTAACACGAACCCCTTTACAATCCGTAAAAGAATAG

Upstream 100 bases:

>100_bases
GGATTTTAGATCATGAAGCTGGTGAAAAACTCTTGCAAATTTTCCAAAGACGGTAAACACTTAAGACAAAAATCCACAAA
AATGAAATAGTTTAGACCTT

Downstream 100 bases:

>100_bases
ATTTCGCGCATAAACAAACTGAAAAGTTACAAATATTCTTATTTCGACTATTGAATTTAAACATTTATTAAGTTAAGATT
AATAATCTTAAGAAAAACCC

Product: O-sialoglycoprotein

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MLVLGIESTCDETACAIVRDGKDILSNIVASQIDLHKEYGGVVPELACRRHIDLIIPVIDQALNQAKLTLEQIDLIAVAN
GPGLIGALLIGLNTAKALALALRKPFIGINHVEAHLYAAIMSHPQDFQFPCLGVVLSGGHTALVLIKQIGQYELIGQTVD
DAVGEAFDKVAKMLNLPYPGGPEIENLARHGRSVKFNFKAGQVKGRPLDFSFSGLKTAVLYAIKDPKALKEMVLLSSEMT
QDIAASFQEAACSDIVKKSLLAAKQYGVNTLLFGGGVTNNCYLRKLFSVANSNLNYIWPSAGLSLDNAAMIAGLGYYRYQ
LQNKSDSMDLEPLTRTPLQSVKE

Sequences:

>Translated_343_residues
MLVLGIESTCDETACAIVRDGKDILSNIVASQIDLHKEYGGVVPELACRRHIDLIIPVIDQALNQAKLTLEQIDLIAVAN
GPGLIGALLIGLNTAKALALALRKPFIGINHVEAHLYAAIMSHPQDFQFPCLGVVLSGGHTALVLIKQIGQYELIGQTVD
DAVGEAFDKVAKMLNLPYPGGPEIENLARHGRSVKFNFKAGQVKGRPLDFSFSGLKTAVLYAIKDPKALKEMVLLSSEMT
QDIAASFQEAACSDIVKKSLLAAKQYGVNTLLFGGGVTNNCYLRKLFSVANSNLNYIWPSAGLSLDNAAMIAGLGYYRYQ
LQNKSDSMDLEPLTRTPLQSVKE
>Mature_343_residues
MLVLGIESTCDETACAIVRDGKDILSNIVASQIDLHKEYGGVVPELACRRHIDLIIPVIDQALNQAKLTLEQIDLIAVAN
GPGLIGALLIGLNTAKALALALRKPFIGINHVEAHLYAAIMSHPQDFQFPCLGVVLSGGHTALVLIKQIGQYELIGQTVD
DAVGEAFDKVAKMLNLPYPGGPEIENLARHGRSVKFNFKAGQVKGRPLDFSFSGLKTAVLYAIKDPKALKEMVLLSSEMT
QDIAASFQEAACSDIVKKSLLAAKQYGVNTLLFGGGVTNNCYLRKLFSVANSNLNYIWPSAGLSLDNAAMIAGLGYYRYQ
LQNKSDSMDLEPLTRTPLQSVKE

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=339, Percent_Identity=32.1533923303835, Blast_Score=158, Evalue=7e-39,
Organism=Homo sapiens, GI8923380, Length=334, Percent_Identity=28.4431137724551, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI1789445, Length=331, Percent_Identity=41.0876132930514, Blast_Score=243, Evalue=1e-65,
Organism=Caenorhabditis elegans, GI17557464, Length=359, Percent_Identity=29.2479108635098, Blast_Score=118, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI71995670, Length=321, Percent_Identity=30.2180685358255, Blast_Score=102, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6320099, Length=366, Percent_Identity=30.0546448087432, Blast_Score=129, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6322891, Length=317, Percent_Identity=27.1293375394322, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI20129063, Length=358, Percent_Identity=32.4022346368715, Blast_Score=159, Evalue=4e-39,
Organism=Drosophila melanogaster, GI21357207, Length=326, Percent_Identity=28.8343558282209, Blast_Score=103, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_PARUW (Q6MD07)

Other databases:

- EMBL:   BX908798
- RefSeq:   YP_007817.1
- ProteinModelPortal:   Q6MD07
- SMR:   Q6MD07
- STRING:   Q6MD07
- MEROPS:   M22.001
- GeneID:   2781206
- GenomeReviews:   BX908798_GR
- KEGG:   pcu:pc0818
- NMPDR:   fig|264201.1.peg.818
- eggNOG:   COG0533
- HOGENOM:   HBG304663
- OMA:   MEVIGQT
- PhylomeDB:   Q6MD07
- ProtClustDB:   CLSK2762266
- BioCyc:   CPRO264201:PC0818-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 37038; Mature: 37038

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVLGIESTCDETACAIVRDGKDILSNIVASQIDLHKEYGGVVPELACRRHIDLIIPVID
CEEECCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
QALNQAKLTLEQIDLIAVANGPGLIGALLIGLNTAKALALALRKPFIGINHVEAHLYAAI
HHHHHHHHHHHHEEEEEEECCCCHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHH
MSHPQDFQFPCLGVVLSGGHTALVLIKQIGQYELIGQTVDDAVGEAFDKVAKMLNLPYPG
HCCCCCCCCCEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GPEIENLARHGRSVKFNFKAGQVKGRPLDFSFSGLKTAVLYAIKDPKALKEMVLLSSEMT
CCCHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHEEEEEEECCHHHHHHHHHHHHHHH
QDIAASFQEAACSDIVKKSLLAAKQYGVNTLLFGGGVTNNCYLRKLFSVANSNLNYIWPS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCCCCEECCC
AGLSLDNAAMIAGLGYYRYQLQNKSDSMDLEPLTRTPLQSVKE
CCCCCCCHHHHHHCHHEEEEECCCCCCCCCCCCCCCHHHHHCC
>Mature Secondary Structure
MLVLGIESTCDETACAIVRDGKDILSNIVASQIDLHKEYGGVVPELACRRHIDLIIPVID
CEEECCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
QALNQAKLTLEQIDLIAVANGPGLIGALLIGLNTAKALALALRKPFIGINHVEAHLYAAI
HHHHHHHHHHHHEEEEEEECCCCHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHH
MSHPQDFQFPCLGVVLSGGHTALVLIKQIGQYELIGQTVDDAVGEAFDKVAKMLNLPYPG
HCCCCCCCCCEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GPEIENLARHGRSVKFNFKAGQVKGRPLDFSFSGLKTAVLYAIKDPKALKEMVLLSSEMT
CCCHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHEEEEEEECCHHHHHHHHHHHHHHH
QDIAASFQEAACSDIVKKSLLAAKQYGVNTLLFGGGVTNNCYLRKLFSVANSNLNYIWPS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCCCCEECCC
AGLSLDNAAMIAGLGYYRYQLQNKSDSMDLEPLTRTPLQSVKE
CCCCCCCHHHHHHCHHEEEEECCCCCCCCCCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA