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The map label for this gene is aspC [H]

Identifier: 46446319

GI number: 46446319

Start: 833564

End: 834826

Strand: Reverse

Name: aspC [H]

Synonym: pc0685

Alternate gene names: 46446319

Gene position: 834826-833564 (Counterclockwise)

Preceding gene: 46446320

Following gene: 46446318

Centisome position: 34.58

GC content: 38.4

Gene sequence:

>1263_bases
ATGAACTTCCTCAAGAGTGGATCTCTCATGGTTAAGCGTAATGTGCATTTGACAAAACTCCAATCAGGGTATTTATTTCC
AGAAATCAATCGAAGGAAAAATGAATTTTTAAAAAAACATCCTTCCGCTCAATTAATTAATTTAGGCATCGGTGACACTA
CGCAACCCATCCCTCTTTATATTTCTGAAGCGATGCAAAATTTTGCCAAACAATTAGCCTCAGAAAAAACTTACAGAGGT
TATGGAACAGAACAGGGTTCGATACTTCTTAGAGAAGCGATTGCTGAGCAGTATTACCAAGGCAAAATTGATCCTCAAGA
AGTTTTTGTTTCAGACGGATCTAAATGTGATGTGGGTCGTTTGCAAATCCTTTTTGGATCAGATGCAACTATCGCCGTAC
AAAATCCTACTTATCCTGCTTATGTAGATACCGGTGTGATTAATGGGCAAGCATCCTTCTTTCAAACATCTACTAAACAA
TATCAGAGAATAACTTATATGAGTTGTTTACCTGAAAACAATTTTTTTCCTGACTTAGCAAATTTACCAAAAACAGATTT
GATTTATTTTTGTTCTCCTAATAATCCAACGGGCAGTGCTGCAACAAACGAACAATTAAGGGAATTAGTTCAATTTGCCA
AAAAGCGCCAATCTATCATTATTTTCGATGCTGCTTATGCAAGCTTCGTCAGAAGTTCACATATCCCTCGTTCAATCTAT
GAAATTGAAGGGGCGAAAGAAGTGGCCATTGAAGTAGGCTCTTTTTCTAAAATGATTGGGTTCACAGGTGTTCGCTTGGG
TTGGAGTGTTGTTCCAAAACAACTGCGTTTTGAAGATGGTCATTCAGTTCAACAAGATTGGGAGCGAATTGTCTGCACTT
TTTTTAATGGCGCCTCAAATATTGCCCAAGCAGGAGGATTAGCCGCCCTACAAAAAGAGGGATTGCAAGCCATTGACGAA
CTTTCCAGCTATTATATGAAGAATAGCAATATCCTTAAAAAAGCTTTTGAAGAGTGTGGATATAAGGTGTATGGAGGAGA
AAATGTTCCTTATCTATGGGTTCATTTTCCACAACTAACGTCTTGGGAAGCTTTTGAAATCCTACTTAAACAATCGCAAC
TTGTCAGCGTCCCAGGTAGTGGATTTGGATCGGCTGGAGAAGGGTTTTTGCGCTTTAGTGCTTTTGGTAAACAATCTGAC
ATTACTGTCGCTTTGCCCAGAATCAAACATGCTTTATTGAAGATTAAGCCTACAGTTTACTGA

Upstream 100 bases:

>100_bases
AAAGCGGCCTTATCTTTAAGTAAACTGCCAGCAGGTTCCTGCCGTCTCCCTTTATGTGATCTCAGTCAGAATCATTCCCA
AAAGCTAGCTCAAATTCTTA

Downstream 100 bases:

>100_bases
TTGAAGGAATTTAAGCTTGTTCACTTAAAAATCTTTGATAAGCATCTCAAATAGATCTGGCCATTTTCTGTCGCAATTAG
AATCCCTTAAGTTGAATAAA

Product: L,L-diaminopimelate aminotransferase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MNFLKSGSLMVKRNVHLTKLQSGYLFPEINRRKNEFLKKHPSAQLINLGIGDTTQPIPLYISEAMQNFAKQLASEKTYRG
YGTEQGSILLREAIAEQYYQGKIDPQEVFVSDGSKCDVGRLQILFGSDATIAVQNPTYPAYVDTGVINGQASFFQTSTKQ
YQRITYMSCLPENNFFPDLANLPKTDLIYFCSPNNPTGSAATNEQLRELVQFAKKRQSIIIFDAAYASFVRSSHIPRSIY
EIEGAKEVAIEVGSFSKMIGFTGVRLGWSVVPKQLRFEDGHSVQQDWERIVCTFFNGASNIAQAGGLAALQKEGLQAIDE
LSSYYMKNSNILKKAFEECGYKVYGGENVPYLWVHFPQLTSWEAFEILLKQSQLVSVPGSGFGSAGEGFLRFSAFGKQSD
ITVALPRIKHALLKIKPTVY

Sequences:

>Translated_420_residues
MNFLKSGSLMVKRNVHLTKLQSGYLFPEINRRKNEFLKKHPSAQLINLGIGDTTQPIPLYISEAMQNFAKQLASEKTYRG
YGTEQGSILLREAIAEQYYQGKIDPQEVFVSDGSKCDVGRLQILFGSDATIAVQNPTYPAYVDTGVINGQASFFQTSTKQ
YQRITYMSCLPENNFFPDLANLPKTDLIYFCSPNNPTGSAATNEQLRELVQFAKKRQSIIIFDAAYASFVRSSHIPRSIY
EIEGAKEVAIEVGSFSKMIGFTGVRLGWSVVPKQLRFEDGHSVQQDWERIVCTFFNGASNIAQAGGLAALQKEGLQAIDE
LSSYYMKNSNILKKAFEECGYKVYGGENVPYLWVHFPQLTSWEAFEILLKQSQLVSVPGSGFGSAGEGFLRFSAFGKQSD
ITVALPRIKHALLKIKPTVY
>Mature_420_residues
MNFLKSGSLMVKRNVHLTKLQSGYLFPEINRRKNEFLKKHPSAQLINLGIGDTTQPIPLYISEAMQNFAKQLASEKTYRG
YGTEQGSILLREAIAEQYYQGKIDPQEVFVSDGSKCDVGRLQILFGSDATIAVQNPTYPAYVDTGVINGQASFFQTSTKQ
YQRITYMSCLPENNFFPDLANLPKTDLIYFCSPNNPTGSAATNEQLRELVQFAKKRQSIIIFDAAYASFVRSSHIPRSIY
EIEGAKEVAIEVGSFSKMIGFTGVRLGWSVVPKQLRFEDGHSVQQDWERIVCTFFNGASNIAQAGGLAALQKEGLQAIDE
LSSYYMKNSNILKKAFEECGYKVYGGENVPYLWVHFPQLTSWEAFEILLKQSQLVSVPGSGFGSAGEGFLRFSAFGKQSD
ITVALPRIKHALLKIKPTVY

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788722, Length=380, Percent_Identity=26.3157894736842, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1788627, Length=243, Percent_Identity=26.3374485596708, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17567663, Length=245, Percent_Identity=25.3061224489796, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019942
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 46890; Mature: 46890

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFLKSGSLMVKRNVHLTKLQSGYLFPEINRRKNEFLKKHPSAQLINLGIGDTTQPIPLY
CCCCCCCCEEEEECCEEEEECCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCHHHH
ISEAMQNFAKQLASEKTYRGYGTEQGSILLREAIAEQYYQGKIDPQEVFVSDGSKCDVGR
HHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHEECCCCCCCCCE
LQILFGSDATIAVQNPTYPAYVDTGVINGQASFFQTSTKQYQRITYMSCLPENNFFPDLA
EEEEECCCCEEEEECCCCCCEEECCEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
NLPKTDLIYFCSPNNPTGSAATNEQLRELVQFAKKRQSIIIFDAAYASFVRSSHIPRSIY
CCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCCCHHH
EIEGAKEVAIEVGSFSKMIGFTGVRLGWSVVPKQLRFEDGHSVQQDWERIVCTFFNGASN
HHCCCCEEEEECCCHHHHHHCCCHHCCHHHCCHHHCCCCCCCHHHHHHHHHHHHHCCHHH
IAQAGGLAALQKEGLQAIDELSSYYMKNSNILKKAFEECGYKVYGGENVPYLWVHFPQLT
HHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEECCCCCCEEEEECCCCC
SWEAFEILLKQSQLVSVPGSGFGSAGEGFLRFSAFGKQSDITVALPRIKHALLKIKPTVY
CHHHHHHHHHHCCEEECCCCCCCCCCCCEEEEEECCCCCCEEEEHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNFLKSGSLMVKRNVHLTKLQSGYLFPEINRRKNEFLKKHPSAQLINLGIGDTTQPIPLY
CCCCCCCCEEEEECCEEEEECCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCHHHH
ISEAMQNFAKQLASEKTYRGYGTEQGSILLREAIAEQYYQGKIDPQEVFVSDGSKCDVGR
HHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHEECCCCCCCCCE
LQILFGSDATIAVQNPTYPAYVDTGVINGQASFFQTSTKQYQRITYMSCLPENNFFPDLA
EEEEECCCCEEEEECCCCCCEEECCEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
NLPKTDLIYFCSPNNPTGSAATNEQLRELVQFAKKRQSIIIFDAAYASFVRSSHIPRSIY
CCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCCCHHH
EIEGAKEVAIEVGSFSKMIGFTGVRLGWSVVPKQLRFEDGHSVQQDWERIVCTFFNGASN
HHCCCCEEEEECCCHHHHHHCCCHHCCHHHCCHHHCCCCCCCHHHHHHHHHHHHHCCHHH
IAQAGGLAALQKEGLQAIDELSSYYMKNSNILKKAFEECGYKVYGGENVPYLWVHFPQLT
HHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEECCCCCCEEEEECCCCC
SWEAFEILLKQSQLVSVPGSGFGSAGEGFLRFSAFGKQSDITVALPRIKHALLKIKPTVY
CHHHHHHHHHHCCEEECCCCCCCCCCCCEEEEEECCCCCCEEEEHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA