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The map label for this gene is ppnK

Identifier: 46446252

GI number: 46446252

Start: 758693

End: 759532

Strand: Reverse

Name: ppnK

Synonym: pc0618

Alternate gene names: 46446252

Gene position: 759532-758693 (Counterclockwise)

Preceding gene: 46446253

Following gene: 46446251

Centisome position: 31.46

GC content: 35.83

Gene sequence:

>840_bases
ATGATTGCACTATTTCCTAATGAAAGTAAAGATCCCTCCTTAAAAATTGCAGCAGAGATTTGCCAGTTTTTGATTTCTCG
AAATATTGAAATTACTGCCGAAGATAAACATGCCAAACAATTAAACGTATTTCCCCTATCACAAGTAAACGTTCAACATA
TCAATTTTCGTATTTCTCTCGGAGGAGATGGCACAATCTTACGACTCATTCATAAACACCCAACTATTCATGCTCCTTTA
CTTGGAATTAATTTAGGAAGTCTTGGTTTTTTAGCTGACATTCCGTTAGATGGCATTTTTCCAAGCTTAGAAGATTTAAT
TAAAGGACGTTATCGTGTTCAAAAACGGATGATGGTGGAAGGTTCTGTATTATGTAAGCCCTCTTGTTTTGCAGTTAATG
AAGTCGTTATTCACCGTGCTCAGAATCCATGCTTAATTGATTTAGCTATTTATGTGGATGGAAACTATCTCAACACTTTT
TCAGCTGATGGGATGATTATCTCGACTCCTAGTGGATCAACAGCATACTCTTTGGCAGCCGGCGGCCCGATTTTAACGCC
AGAATTAAAAGCTTTTGTTCTTACTCCTATTTGTCCCCATACGATTTCTAATCGCCCCATTGTTTTAATGCCAGAAATAT
CTATTCAAGTTAAATATTTAAGTTCCTACGCTCCCGTTGAAGTTTCCTCAGATGGCATATCGAGTTTTAGCTTATCAACA
AACGAAATTTTTCATGCTTCTATTTCTTCTCAAACTTTTGATTTAGTTTGCTTAGAAAGGCATGATTATTTCGCTACTCT
AAGAGAAAAACTAGGATGGCAAGGAAAATTAAAAATTTAA

Upstream 100 bases:

>100_bases
CAATCTCATTTTAATTTAATAGCACAAAATACCCTTAATCCTGTTGCTTAAATTATTTTCAAAGTTTGTAAGACATACTT
GAACAAGTAGATATGCTATG

Downstream 100 bases:

>100_bases
AAATTTCCTTATTTTCATTTTTTATAAAGTTTTAATTTTATGAATCTAACCAATTCTTTGTGTTTAACAAAACTTTCAAG
AAATCTACTACCTTAATCAT

Product: hypothetical protein

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MIALFPNESKDPSLKIAAEICQFLISRNIEITAEDKHAKQLNVFPLSQVNVQHINFRISLGGDGTILRLIHKHPTIHAPL
LGINLGSLGFLADIPLDGIFPSLEDLIKGRYRVQKRMMVEGSVLCKPSCFAVNEVVIHRAQNPCLIDLAIYVDGNYLNTF
SADGMIISTPSGSTAYSLAAGGPILTPELKAFVLTPICPHTISNRPIVLMPEISIQVKYLSSYAPVEVSSDGISSFSLST
NEIFHASISSQTFDLVCLERHDYFATLREKLGWQGKLKI

Sequences:

>Translated_279_residues
MIALFPNESKDPSLKIAAEICQFLISRNIEITAEDKHAKQLNVFPLSQVNVQHINFRISLGGDGTILRLIHKHPTIHAPL
LGINLGSLGFLADIPLDGIFPSLEDLIKGRYRVQKRMMVEGSVLCKPSCFAVNEVVIHRAQNPCLIDLAIYVDGNYLNTF
SADGMIISTPSGSTAYSLAAGGPILTPELKAFVLTPICPHTISNRPIVLMPEISIQVKYLSSYAPVEVSSDGISSFSLST
NEIFHASISSQTFDLVCLERHDYFATLREKLGWQGKLKI
>Mature_279_residues
MIALFPNESKDPSLKIAAEICQFLISRNIEITAEDKHAKQLNVFPLSQVNVQHINFRISLGGDGTILRLIHKHPTIHAPL
LGINLGSLGFLADIPLDGIFPSLEDLIKGRYRVQKRMMVEGSVLCKPSCFAVNEVVIHRAQNPCLIDLAIYVDGNYLNTF
SADGMIISTPSGSTAYSLAAGGPILTPELKAFVLTPICPHTISNRPIVLMPEISIQVKYLSSYAPVEVSSDGISSFSLST
NEIFHASISSQTFDLVCLERHDYFATLREKLGWQGKLKI

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family

Homologues:

Organism=Homo sapiens, GI55743112, Length=263, Percent_Identity=30.7984790874525, Blast_Score=88, Evalue=1e-17,
Organism=Escherichia coli, GI1788968, Length=265, Percent_Identity=33.5849056603774, Blast_Score=155, Evalue=4e-39,
Organism=Saccharomyces cerevisiae, GI6322509, Length=240, Percent_Identity=31.6666666666667, Blast_Score=122, Evalue=6e-29,
Organism=Saccharomyces cerevisiae, GI6320794, Length=239, Percent_Identity=30.1255230125523, Blast_Score=119, Evalue=7e-28,
Organism=Saccharomyces cerevisiae, GI6325068, Length=207, Percent_Identity=34.7826086956522, Blast_Score=117, Evalue=2e-27,
Organism=Drosophila melanogaster, GI161077047, Length=250, Percent_Identity=30.4, Blast_Score=100, Evalue=8e-22,
Organism=Drosophila melanogaster, GI28573832, Length=255, Percent_Identity=29.8039215686275, Blast_Score=100, Evalue=9e-22,
Organism=Drosophila melanogaster, GI28573826, Length=255, Percent_Identity=29.8039215686275, Blast_Score=100, Evalue=9e-22,
Organism=Drosophila melanogaster, GI28573830, Length=255, Percent_Identity=29.8039215686275, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28573828, Length=252, Percent_Identity=30.1587301587302, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI281363323, Length=271, Percent_Identity=28.4132841328413, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI281363321, Length=271, Percent_Identity=28.4132841328413, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI20129957, Length=271, Percent_Identity=28.4132841328413, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24653424, Length=271, Percent_Identity=28.4132841328413, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24653422, Length=271, Percent_Identity=28.4132841328413, Blast_Score=88, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPNK_PARUW (Q6MDK7)

Other databases:

- EMBL:   BX908798
- RefSeq:   YP_007617.1
- ProteinModelPortal:   Q6MDK7
- SMR:   Q6MDK7
- STRING:   Q6MDK7
- GeneID:   2780280
- GenomeReviews:   BX908798_GR
- KEGG:   pcu:pc0618
- NMPDR:   fig|264201.1.peg.618
- eggNOG:   COG0061
- HOGENOM:   HBG713904
- OMA:   KLHWAGS
- PhylomeDB:   Q6MDK7
- ProtClustDB:   CLSK2762201
- BioCyc:   CPRO264201:PC0618-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00361
- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504
- Gene3D:   G3DSA:2.60.200.30
- Gene3D:   G3DSA:3.40.50.10330
- PANTHER:   PTHR20275

Pfam domain/function: PF01513 NAD_kinase; SSF111331 ATP-NAD_kinase_PpnK-typ

EC number: =2.7.1.23

Molecular weight: Translated: 30646; Mature: 30646

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIALFPNESKDPSLKIAAEICQFLISRNIEITAEDKHAKQLNVFPLSQVNVQHINFRISL
CEEECCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCEEEEEECCCCEEEEEEEEEEE
GGDGTILRLIHKHPTIHAPLLGINLGSLGFLADIPLDGIFPSLEDLIKGRYRVQKRMMVE
CCCCEEEEEEECCCCEECEEEEEECCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHEEC
GSVLCKPSCFAVNEVVIHRAQNPCLIDLAIYVDGNYLNTFSADGMIISTPSGSTAYSLAA
CCEEECCCCHHHHHHHEECCCCCEEEEEEEEEECCEEEEECCCCEEEECCCCCCEEEEEC
GGPILTPELKAFVLTPICPHTISNRPIVLMPEISIQVKYLSSYAPVEVSSDGISSFSLST
CCCEECCCCEEEEECCCCCCCCCCCCEEEECCCEEEEEEECCCCCEEECCCCCCEEEECC
NEIFHASISSQTFDLVCLERHDYFATLREKLGWQGKLKI
CEEEEEECCCCEEEEEEEECCHHHHHHHHHCCCCEEECC
>Mature Secondary Structure
MIALFPNESKDPSLKIAAEICQFLISRNIEITAEDKHAKQLNVFPLSQVNVQHINFRISL
CEEECCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCEEEEEECCCCEEEEEEEEEEE
GGDGTILRLIHKHPTIHAPLLGINLGSLGFLADIPLDGIFPSLEDLIKGRYRVQKRMMVE
CCCCEEEEEEECCCCEECEEEEEECCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHEEC
GSVLCKPSCFAVNEVVIHRAQNPCLIDLAIYVDGNYLNTFSADGMIISTPSGSTAYSLAA
CCEEECCCCHHHHHHHEECCCCCEEEEEEEEEECCEEEEECCCCEEEECCCCCCEEEEEC
GGPILTPELKAFVLTPICPHTISNRPIVLMPEISIQVKYLSSYAPVEVSSDGISSFSLST
CCCEECCCCEEEEECCCCCCCCCCCCEEEECCCEEEEEEECCCCCEEECCCCCCEEEECC
NEIFHASISSQTFDLVCLERHDYFATLREKLGWQGKLKI
CEEEEEECCCCEEEEEEEECCHHHHHHHHHCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA