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The map label for this gene is cdsA [H]

Identifier: 46445954

GI number: 46445954

Start: 438511

End: 439449

Strand: Reverse

Name: cdsA [H]

Synonym: pc0320

Alternate gene names: 46445954

Gene position: 439449-438511 (Counterclockwise)

Preceding gene: 46445955

Following gene: 46445953

Centisome position: 18.2

GC content: 36.0

Gene sequence:

>939_bases
TTGCACCTGTCCTTTGGCCAGATTTTACTCCTAATCATCTTCTGGAAGCCATTGTCGATTATCAAAAAAGAGAAAGAAGA
TGGGGAGGCGTATAAATTGGCAAATCAGTTTAAACAACGAGTTGTCACAAGCAGCGTGACTATTTTCTTAGTCATTATCT
CGATTTATTTTTCTCATGTTCCTTACTTTAAACCTATTTTTGTATTACTTAATGCAGCAATTATCTCATTGGCTCTTCTC
GAGTATTATCAATTGGCACATTATAAAGGATTTCAACCTTTAAATTTATTAGGTGTGGGAACAACAACAGCTTATGTCAT
CAGCAGTTTTTACGCTGGACAAGAACCCAATTTATCTGATCTTCCTCTTTTTGTTTTATTAGGCTGTCTTCTACTATTTT
TTTTAGCCTATTTTAATAAACAGTTAGAACCCTTAGGTAATATTGCTGTCAACCTATTCGGAATTGGCTATGTCGTCATC
CCTTTGACATGTGCTTTGCAAATCAATTATTTTTCATCTCCTCATATAACTGATGGACGTTTGTGGCTCGCCTATGCACT
TGCTGTTACCAAAATGACAGATGTTGGTGGATATATAAGCGGAAAAATTTTCGGAAAAATCAAATTAGCTTCTCATATTA
GCCCCAAAAAAACTATCGAAGGTTCCATTGGAGGTTTAATATTGTCTCTTTTGACTAGCCTAGCTTTTTATTATTTTGTA
TTCCCTTTTAAACATCCAATCTCCTTTTGGCAAAGTATATGGCTAGGAATAGTCATCAGTGTACTTTCTCAATTCGGAGA
CTTATCTGAATCCATCTTAAAGAGAGACGCTGGGGTCAAAGATAGCAGTCAACTACCGGGTTTAGGGGGCATCCTTGATA
TGACAGATTCTCTTGTTTTTACCTTGCCTTTAGTGTATCTTTGGCTAAAAGTTTCATGA

Upstream 100 bases:

>100_bases
ACCCATCAATGGCCAGATCCTGAGCTATTAATTCGAACAAGTGGTGAAATGAGAATTAGTAATTTTCTTCTTTGGCAAAT
TTCTTATACAGAAATTTATA

Downstream 100 bases:

>100_bases
CATGAGTAAAATCTTTCCTCTATAATATGAGGATATTAAATATGAGAAATTTATGATCATTACTATTGATGGACCTGTTG
CAACAGGAAAAAGTACAATT

Product: putative phosphatidate cytidylyltransferase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MHLSFGQILLLIIFWKPLSIIKKEKEDGEAYKLANQFKQRVVTSSVTIFLVIISIYFSHVPYFKPIFVLLNAAIISLALL
EYYQLAHYKGFQPLNLLGVGTTTAYVISSFYAGQEPNLSDLPLFVLLGCLLLFFLAYFNKQLEPLGNIAVNLFGIGYVVI
PLTCALQINYFSSPHITDGRLWLAYALAVTKMTDVGGYISGKIFGKIKLASHISPKKTIEGSIGGLILSLLTSLAFYYFV
FPFKHPISFWQSIWLGIVISVLSQFGDLSESILKRDAGVKDSSQLPGLGGILDMTDSLVFTLPLVYLWLKVS

Sequences:

>Translated_312_residues
MHLSFGQILLLIIFWKPLSIIKKEKEDGEAYKLANQFKQRVVTSSVTIFLVIISIYFSHVPYFKPIFVLLNAAIISLALL
EYYQLAHYKGFQPLNLLGVGTTTAYVISSFYAGQEPNLSDLPLFVLLGCLLLFFLAYFNKQLEPLGNIAVNLFGIGYVVI
PLTCALQINYFSSPHITDGRLWLAYALAVTKMTDVGGYISGKIFGKIKLASHISPKKTIEGSIGGLILSLLTSLAFYYFV
FPFKHPISFWQSIWLGIVISVLSQFGDLSESILKRDAGVKDSSQLPGLGGILDMTDSLVFTLPLVYLWLKVS
>Mature_312_residues
MHLSFGQILLLIIFWKPLSIIKKEKEDGEAYKLANQFKQRVVTSSVTIFLVIISIYFSHVPYFKPIFVLLNAAIISLALL
EYYQLAHYKGFQPLNLLGVGTTTAYVISSFYAGQEPNLSDLPLFVLLGCLLLFFLAYFNKQLEPLGNIAVNLFGIGYVVI
PLTCALQINYFSSPHITDGRLWLAYALAVTKMTDVGGYISGKIFGKIKLASHISPKKTIEGSIGGLILSLLTSLAFYYFV
FPFKHPISFWQSIWLGIVISVLSQFGDLSESILKRDAGVKDSSQLPGLGGILDMTDSLVFTLPLVYLWLKVS

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=141, Percent_Identity=39.7163120567376, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787677, Length=122, Percent_Identity=38.5245901639344, Blast_Score=85, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 34714; Mature: 34714

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLSFGQILLLIIFWKPLSIIKKEKEDGEAYKLANQFKQRVVTSSVTIFLVIISIYFSHV
CCCCHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PYFKPIFVLLNAAIISLALLEYYQLAHYKGFQPLNLLGVGTTTAYVISSFYAGQEPNLSD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHCCCCCCCCC
LPLFVLLGCLLLFFLAYFNKQLEPLGNIAVNLFGIGYVVIPLTCALQINYFSSPHITDGR
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCH
LWLAYALAVTKMTDVGGYISGKIFGKIKLASHISPKKTIEGSIGGLILSLLTSLAFYYFV
HHHHHHHHHHHHHHCCCCCCCHHEEEEEHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHH
FPFKHPISFWQSIWLGIVISVLSQFGDLSESILKRDAGVKDSSQLPGLGGILDMTDSLVF
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHH
TLPLVYLWLKVS
HHHHHHHHHCCC
>Mature Secondary Structure
MHLSFGQILLLIIFWKPLSIIKKEKEDGEAYKLANQFKQRVVTSSVTIFLVIISIYFSHV
CCCCHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PYFKPIFVLLNAAIISLALLEYYQLAHYKGFQPLNLLGVGTTTAYVISSFYAGQEPNLSD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHCCCCCCCCC
LPLFVLLGCLLLFFLAYFNKQLEPLGNIAVNLFGIGYVVIPLTCALQINYFSSPHITDGR
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCH
LWLAYALAVTKMTDVGGYISGKIFGKIKLASHISPKKTIEGSIGGLILSLLTSLAFYYFV
HHHHHHHHHHHHHHCCCCCCCHHEEEEEHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHH
FPFKHPISFWQSIWLGIVISVLSQFGDLSESILKRDAGVKDSSQLPGLGGILDMTDSLVF
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHH
TLPLVYLWLKVS
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]