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The map label for this gene is comF [H]

Identifier: 46445939

GI number: 46445939

Start: 422258

End: 422983

Strand: Direct

Name: comF [H]

Synonym: pc0305

Alternate gene names: 46445939

Gene position: 422258-422983 (Clockwise)

Preceding gene: 46445938

Following gene: 46445942

Centisome position: 17.49

GC content: 34.57

Gene sequence:

>726_bases
ATGTATTGGTGGCAGGAGATTAAAAAATCCTGGATCCATTTTGTTTTTCCCGCTACCTGTTTATATTGTAAAGAAAGTTT
ACAACCTAGCCAAGCTGTTTTTTGTTATGCTTGTGCTTCTCTATTAGAATTGATTAATCCCCAAGAAAGATGCCCCATTT
GTTTTGATTTAAAAAATAATACCTTCGTGCATAAATGTGAAAGATGTAAGGCTTTTCCTTCACTTTTTTTACGCCAAGCT
TCAGCTTTTGATTATTTTGGTCCAGCTCAAACGCTTGTCAAACAATTAAAATATGGAAATCAACCTCATTTGGCGAAGGG
GATGGCAGCATTTTTAATGACTCAATTTGATCGATTAAAGTGGCCATTGCCTGATATCGTAATCCCTGTTCCTATGTCTT
TTTCTCATTGGTTAAAAAGAGGATATAATCAAAGTTTTTTATTAGCTGAAGAAATGGCAAAAATTCTTCACATCCCTCTT
TTCAATTGTCTTAAATATACTTCGGGTAATTACGGACAAGCCTCTTTGAATTTAGGACAAAGAAAACAGCTTAAACAAGT
ATTCAAGTTGAAAAAAACGTTTCAGATTCAGGATAAGAGGGTGTTACTCATCGATGATGTCATGACAACAGGAACAACTC
TTCATAAATGTGCGGAGGCTTTAAGTGAAGGTTTTCCTGGTTCTCTTTATGCTTTAACTTTTTGTCGTACAACTGTTTAT
GATTAA

Upstream 100 bases:

>100_bases
ATTATAATGAATGGATAGGAGAAATATTTGATCCTGCAAAAATTGATTTAAATCATTATCGAAAAAATCGTCATGTTTTG
AATCAGGCAGAGGAATAAAA

Downstream 100 bases:

>100_bases
ATCCATTTTTTTTGTCGGAAGTAATGCAACATCAATAAGCTCAAAGTTAGCATGAACAACATAATCAACGGATATCCAAA
TGGATAATGTAATTCTGGCA

Product: putative competence-related protein comF

Products: NA

Alternate protein names: DNA transformation protein ComF; Protein COM101A [H]

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MYWWQEIKKSWIHFVFPATCLYCKESLQPSQAVFCYACASLLELINPQERCPICFDLKNNTFVHKCERCKAFPSLFLRQA
SAFDYFGPAQTLVKQLKYGNQPHLAKGMAAFLMTQFDRLKWPLPDIVIPVPMSFSHWLKRGYNQSFLLAEEMAKILHIPL
FNCLKYTSGNYGQASLNLGQRKQLKQVFKLKKTFQIQDKRVLLIDDVMTTGTTLHKCAEALSEGFPGSLYALTFCRTTVY
D

Sequences:

>Translated_241_residues
MYWWQEIKKSWIHFVFPATCLYCKESLQPSQAVFCYACASLLELINPQERCPICFDLKNNTFVHKCERCKAFPSLFLRQA
SAFDYFGPAQTLVKQLKYGNQPHLAKGMAAFLMTQFDRLKWPLPDIVIPVPMSFSHWLKRGYNQSFLLAEEMAKILHIPL
FNCLKYTSGNYGQASLNLGQRKQLKQVFKLKKTFQIQDKRVLLIDDVMTTGTTLHKCAEALSEGFPGSLYALTFCRTTVY
D
>Mature_241_residues
MYWWQEIKKSWIHFVFPATCLYCKESLQPSQAVFCYACASLLELINPQERCPICFDLKNNTFVHKCERCKAFPSLFLRQA
SAFDYFGPAQTLVKQLKYGNQPHLAKGMAAFLMTQFDRLKWPLPDIVIPVPMSFSHWLKRGYNQSFLLAEEMAKILHIPL
FNCLKYTSGNYGQASLNLGQRKQLKQVFKLKKTFQIQDKRVLLIDDVMTTGTTLHKCAEALSEGFPGSLYALTFCRTTVY
D

Specific function: Involved in transformation (competence for DNA uptake) [H]

COG id: COG1040

COG function: function code R; Predicted amidophosphoribosyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ComF/GntX family [H]

Homologues:

Organism=Escherichia coli, GI87082263, Length=231, Percent_Identity=26.4069264069264, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005222
- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: NA

Molecular weight: Translated: 27839; Mature: 27839

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
4.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYWWQEIKKSWIHFVFPATCLYCKESLQPSQAVFCYACASLLELINPQERCPICFDLKNN
CCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHCCEEEECCCC
TFVHKCERCKAFPSLFLRQASAFDYFGPAQTLVKQLKYGNQPHLAKGMAAFLMTQFDRLK
CHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHC
WPLPDIVIPVPMSFSHWLKRGYNQSFLLAEEMAKILHIPLFNCLKYTSGNYGQASLNLGQ
CCCCCEEEECCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
RKQLKQVFKLKKTFQIQDKRVLLIDDVMTTGTTLHKCAEALSEGFPGSLYALTFCRTTVY
HHHHHHHHHHHHHHEECCCEEEEEHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
D
C
>Mature Secondary Structure
MYWWQEIKKSWIHFVFPATCLYCKESLQPSQAVFCYACASLLELINPQERCPICFDLKNN
CCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHCCEEEECCCC
TFVHKCERCKAFPSLFLRQASAFDYFGPAQTLVKQLKYGNQPHLAKGMAAFLMTQFDRLK
CHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHC
WPLPDIVIPVPMSFSHWLKRGYNQSFLLAEEMAKILHIPLFNCLKYTSGNYGQASLNLGQ
CCCCCEEEECCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
RKQLKQVFKLKKTFQIQDKRVLLIDDVMTTGTTLHKCAEALSEGFPGSLYALTFCRTTVY
HHHHHHHHHHHHHHEECCCEEEEEHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
D
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1916268; 1856167; 7542800 [H]