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The map label for this gene is sms [H]

Identifier: 46445907

GI number: 46445907

Start: 384258

End: 385628

Strand: Reverse

Name: sms [H]

Synonym: pc0273

Alternate gene names: 46445907

Gene position: 385628-384258 (Counterclockwise)

Preceding gene: 46445908

Following gene: 46445906

Centisome position: 15.97

GC content: 38.66

Gene sequence:

>1371_bases
ATGGCTAAGCAAAAAACTGTCTGGTATTGCTCTGAATGTGGGCACAAACAACTTAAATGGTTAGGACAATGTCCTTCGTG
TACAAACTGGAATACTTTTCAAGAAGAATTAGAATTATCTTCTCTTCCTAAACGTTTTGAGTCCCAAACTGCTATTACAA
CCCGCCCCATCAAATTGAAAGAAGTAAAACTCCAAGAAACACCACGTATTCAAACGAAGATTGGAGAATGTGACCGTTTA
TTAGGAGGAGGTCTTGTTCCGGGTTCGCTCACTTTAGTGGGAGGTGATCCAGGTATTGGAAAATCCACCTTGATGCTACA
ACTTTCTTATGCTTTAGCCAAACAAGGACTTATTGTCTTATATATTTGTGGAGAAGAGTCTGTTGATCAAACCTCTTTAA
GAGCTAATCGATTGGGCATTCAAACAGATAATCTATTTTTACTTTCGGAAACCAATTTCTCTTTAATAAAATCTCAAATC
GATCAACTTAACCCTGATGTTTTAATCGTCGATTCGATTCAAATCGTTTATAAAAGCGAAATTACTTCAGCTCCAGGATC
GGTGACACAAGTACGTGAAACTACAACAGAGTTTATGCATTTAGCTAAAGGACGTGGAATTTCAACATTTTTAATTGGAC
ACGTCACAAAATCTGGCGAAATTGCAGGTCCAAGAGTTTTAGAACATCTTGTGGATACGGTTCTTTACTTTGAAGGTGAT
AAACAACACCATTATCGAATGATTCGAGTTGTTAAAAATCGGTTTGGCCCTACAGATGAAATTGCAGTCTTCCAAATGAA
ACAATCAGGGCTGGTTGAAGTACCCAATCCTTCCGAAATTTTTTTAGAAGAACGAAGAAAAGATAGCATAGGATCTGTCA
TCATACCTACGTTAGAAGGCTCTCGCCCTATTCTTATTGAAGTACAGGCTTTAGTGACGCAAACAGTCTTTAGTACTCCT
TCACGAAGATGCACAGGATTAGATCAAAATAGACTTGCTCTACTACTTGCTGTGCTTGAAAAAAGGATGGGATATCAACT
TCATAAATGTGATGTTTTTGTTTCTGTCGCAGGAGGTCTAAGAATTATAGAACCTGCCATCGATCTAGGCCTTCTTTTGG
CTTCGGCTTCTTCCATGCGTAATTCAATCATTGACCCTGAAACAACTGTCGTTGGAGAAGTGGGTTTGGGAGGCGAGATA
CGAAGCGTTTCGAGAATTGAAAGTCGACTTAAAGAAGCCATTCATATGGGATTTAGACGTTGCATTATCCCTAAAAGAAA
CGCTAAAGGAATTGCTGAAGATATTCTTCGAAAGATTGTGGTACAAGGCGTAGAATTTGTTGAGGAAGCGATCGATGCTT
TACTCAAATAA

Upstream 100 bases:

>100_bases
AGGAAAGGGAACATCCAAAAAAGAAGCTCAGCAAGCTGCCGCTGCTGATGCTCTTTCACGAGTTGAACTTCCTTAATGTT
TTTCTTAAAGGTACGTTTAA

Downstream 100 bases:

>100_bases
TTCCCAACCCTATTCTATCTCTGTCGGGGCTCGTTCTTCACCACTCTCACGTGCGCAAGTACAAGAGATTTTAAAAGCAC
TTAGATCTTTTTATCCTTCT

Product: DNA repair protein RadA

Products: NA

Alternate protein names: DNA repair protein sms homolog [H]

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MAKQKTVWYCSECGHKQLKWLGQCPSCTNWNTFQEELELSSLPKRFESQTAITTRPIKLKEVKLQETPRIQTKIGECDRL
LGGGLVPGSLTLVGGDPGIGKSTLMLQLSYALAKQGLIVLYICGEESVDQTSLRANRLGIQTDNLFLLSETNFSLIKSQI
DQLNPDVLIVDSIQIVYKSEITSAPGSVTQVRETTTEFMHLAKGRGISTFLIGHVTKSGEIAGPRVLEHLVDTVLYFEGD
KQHHYRMIRVVKNRFGPTDEIAVFQMKQSGLVEVPNPSEIFLEERRKDSIGSVIIPTLEGSRPILIEVQALVTQTVFSTP
SRRCTGLDQNRLALLLAVLEKRMGYQLHKCDVFVSVAGGLRIIEPAIDLGLLLASASSMRNSIIDPETTVVGEVGLGGEI
RSVSRIESRLKEAIHMGFRRCIIPKRNAKGIAEDILRKIVVQGVEFVEEAIDALLK

Sequences:

>Translated_456_residues
MAKQKTVWYCSECGHKQLKWLGQCPSCTNWNTFQEELELSSLPKRFESQTAITTRPIKLKEVKLQETPRIQTKIGECDRL
LGGGLVPGSLTLVGGDPGIGKSTLMLQLSYALAKQGLIVLYICGEESVDQTSLRANRLGIQTDNLFLLSETNFSLIKSQI
DQLNPDVLIVDSIQIVYKSEITSAPGSVTQVRETTTEFMHLAKGRGISTFLIGHVTKSGEIAGPRVLEHLVDTVLYFEGD
KQHHYRMIRVVKNRFGPTDEIAVFQMKQSGLVEVPNPSEIFLEERRKDSIGSVIIPTLEGSRPILIEVQALVTQTVFSTP
SRRCTGLDQNRLALLLAVLEKRMGYQLHKCDVFVSVAGGLRIIEPAIDLGLLLASASSMRNSIIDPETTVVGEVGLGGEI
RSVSRIESRLKEAIHMGFRRCIIPKRNAKGIAEDILRKIVVQGVEFVEEAIDALLK
>Mature_455_residues
AKQKTVWYCSECGHKQLKWLGQCPSCTNWNTFQEELELSSLPKRFESQTAITTRPIKLKEVKLQETPRIQTKIGECDRLL
GGGLVPGSLTLVGGDPGIGKSTLMLQLSYALAKQGLIVLYICGEESVDQTSLRANRLGIQTDNLFLLSETNFSLIKSQID
QLNPDVLIVDSIQIVYKSEITSAPGSVTQVRETTTEFMHLAKGRGISTFLIGHVTKSGEIAGPRVLEHLVDTVLYFEGDK
QHHYRMIRVVKNRFGPTDEIAVFQMKQSGLVEVPNPSEIFLEERRKDSIGSVIIPTLEGSRPILIEVQALVTQTVFSTPS
RRCTGLDQNRLALLLAVLEKRMGYQLHKCDVFVSVAGGLRIIEPAIDLGLLLASASSMRNSIIDPETTVVGEVGLGGEIR
SVSRIESRLKEAIHMGFRRCIIPKRNAKGIAEDILRKIVVQGVEFVEEAIDALLK

Specific function: May play a role in the repair of endogenous alkylation damage [H]

COG id: COG1066

COG function: function code O; Predicted ATP-dependent serine protease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recA family. RadA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790850, Length=434, Percent_Identity=45.6221198156682, Blast_Score=388, Evalue=1e-109,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR014774
- InterPro:   IPR004504
- InterPro:   IPR008269
- InterPro:   IPR020568 [H]

Pfam domain/function: PF06745 KaiC; PF05362 Lon_C [H]

EC number: NA

Molecular weight: Translated: 50462; Mature: 50331

Theoretical pI: Translated: 7.96; Mature: 7.96

Prosite motif: PS50162 RECA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKQKTVWYCSECGHKQLKWLGQCPSCTNWNTFQEELELSSLPKRFESQTAITTRPIKLK
CCCCCEEEEHHHCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEECCEEEE
EVKLQETPRIQTKIGECDRLLGGGLVPGSLTLVGGDPGIGKSTLMLQLSYALAKQGLIVL
EECCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHEEEHHHHHHCCEEEE
YICGEESVDQTSLRANRLGIQTDNLFLLSETNFSLIKSQIDQLNPDVLIVDSIQIVYKSE
EECCCCCCCHHHHHHHHCCCEECCEEEEECCCHHHHHHHHHHCCCCEEEEECEEEEEEHH
ITSAPGSVTQVRETTTEFMHLAKGRGISTFLIGHVTKSGEIAGPRVLEHLVDTVLYFEGD
CCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHEECCC
KQHHYRMIRVVKNRFGPTDEIAVFQMKQSGLVEVPNPSEIFLEERRKDSIGSVIIPTLEG
CHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEECCCCHHHHHHHHCCCCCCCEEEEECCC
SRPILIEVQALVTQTVFSTPSRRCTGLDQNRLALLLAVLEKRMGYQLHKCDVFVSVAGGL
CCCEEEEHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEEEEEECCCC
RIIEPAIDLGLLLASASSMRNSIIDPETTVVGEVGLGGEIRSVSRIESRLKEAIHMGFRR
EEEHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
CIIPKRNAKGIAEDILRKIVVQGVEFVEEAIDALLK
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AKQKTVWYCSECGHKQLKWLGQCPSCTNWNTFQEELELSSLPKRFESQTAITTRPIKLK
CCCCEEEEHHHCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEECCEEEE
EVKLQETPRIQTKIGECDRLLGGGLVPGSLTLVGGDPGIGKSTLMLQLSYALAKQGLIVL
EECCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHEEEHHHHHHCCEEEE
YICGEESVDQTSLRANRLGIQTDNLFLLSETNFSLIKSQIDQLNPDVLIVDSIQIVYKSE
EECCCCCCCHHHHHHHHCCCEECCEEEEECCCHHHHHHHHHHCCCCEEEEECEEEEEEHH
ITSAPGSVTQVRETTTEFMHLAKGRGISTFLIGHVTKSGEIAGPRVLEHLVDTVLYFEGD
CCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHEECCC
KQHHYRMIRVVKNRFGPTDEIAVFQMKQSGLVEVPNPSEIFLEERRKDSIGSVIIPTLEG
CHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEECCCCHHHHHHHHCCCCCCCEEEEECCC
SRPILIEVQALVTQTVFSTPSRRCTGLDQNRLALLLAVLEKRMGYQLHKCDVFVSVAGGL
CCCEEEEHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEEEEEECCCC
RIIEPAIDLGLLLASASSMRNSIIDPETTVVGEVGLGGEIRSVSRIESRLKEAIHMGFRR
EEEHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
CIIPKRNAKGIAEDILRKIVVQGVEFVEEAIDALLK
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]