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The map label for this gene is hemD

Identifier: 46445905

GI number: 46445905

Start: 382941

End: 383594

Strand: Reverse

Name: hemD

Synonym: pc0271

Alternate gene names: NA

Gene position: 383594-382941 (Counterclockwise)

Preceding gene: 46445906

Following gene: 46445904

Centisome position: 15.89

GC content: 38.38

Gene sequence:

>654_bases
TTGAGAAAAATCTTATATACAGGTTTAAATCCCGCTCATTATCACTCCACTGACCAATTAACTCATTGTCCTTTAATCAA
AATTATTCCTCGCCCTTTGACTGATCCCTGCATTCAAAAAGCTTTTCGCGACTTTCACCTTTTTACGCATCTGATTTTTA
CTTCTAAAACGAGTATTCATCTCTTACATGATCATCTTTCTCATTTCGGTTTATCATTAGACGATTGGAAATCTAAAACT
TCGATAGCTGTTGGTCAAGTCTCGGGATCTCATTTGCGAGCCCTTGGTATTCAACCTGCGCTAATTGCTAAAGAAGAAAC
GGCAGAGGGACTTATCATTGAATTGCATCCCCTTTCTCTTCAAAAAGCCAGCTTCTTTTGGCCCCATTCTGCCCAAGCTC
GTTCTGTTTTAGTTGATTTTTTTACTGATCGTCACTTGAATTATTACGCTTGCCCTTTTTATGATACTCAATTTCGGCAA
CCTGAATACATCCCTTCATTAGAACAATTTGACGAGATAGTTTTTACAAGTCCTTCAACTGTTCACGCCTTTGCAAAAAT
ATTTGGCTATTTCCCCATCGATAAAAAATATGTCACAATTGGTCCGATCACCCTACAATGCCTCCAAACTTACATACCCC
AACTGAACAGTTGA

Upstream 100 bases:

>100_bases
CAGGAACAACGGTAGAAGGGCAAGGCCAACTGGCCATTATCGCACGAAAGGACGATGCAAAAATGCAAACTCTTTTTGCC
TGCTTAGATGTGAGAAAAAA

Downstream 100 bases:

>100_bases
TTTTTGGTCATTTTTAAGTCTCATTTATTGCTTAATTTTCTCTATTTGTTCAAAATAATATTATTTTAACCAAATGCAAG
TTTTGAATAAAAACTAATTT

Product: uroporphyrinogen-III synthase

Products: NA

Alternate protein names: Uroporphyrinogen III Synthase/Methyltransferase; Porphyrin Biosynthesis Protein HemD; Porphobilinogen Deaminase/Uroporphyrinogen-III Synthase

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MRKILYTGLNPAHYHSTDQLTHCPLIKIIPRPLTDPCIQKAFRDFHLFTHLIFTSKTSIHLLHDHLSHFGLSLDDWKSKT
SIAVGQVSGSHLRALGIQPALIAKEETAEGLIIELHPLSLQKASFFWPHSAQARSVLVDFFTDRHLNYYACPFYDTQFRQ
PEYIPSLEQFDEIVFTSPSTVHAFAKIFGYFPIDKKYVTIGPITLQCLQTYIPQLNS

Sequences:

>Translated_217_residues
MRKILYTGLNPAHYHSTDQLTHCPLIKIIPRPLTDPCIQKAFRDFHLFTHLIFTSKTSIHLLHDHLSHFGLSLDDWKSKT
SIAVGQVSGSHLRALGIQPALIAKEETAEGLIIELHPLSLQKASFFWPHSAQARSVLVDFFTDRHLNYYACPFYDTQFRQ
PEYIPSLEQFDEIVFTSPSTVHAFAKIFGYFPIDKKYVTIGPITLQCLQTYIPQLNS
>Mature_217_residues
MRKILYTGLNPAHYHSTDQLTHCPLIKIIPRPLTDPCIQKAFRDFHLFTHLIFTSKTSIHLLHDHLSHFGLSLDDWKSKT
SIAVGQVSGSHLRALGIQPALIAKEETAEGLIIELHPLSLQKASFFWPHSAQARSVLVDFFTDRHLNYYACPFYDTQFRQ
PEYIPSLEQFDEIVFTSPSTVHAFAKIFGYFPIDKKYVTIGPITLQCLQTYIPQLNS

Specific function: Unknown

COG id: COG1587

COG function: function code H; Uroporphyrinogen-III synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 24839; Mature: 24839

Theoretical pI: Translated: 7.74; Mature: 7.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKILYTGLNPAHYHSTDQLTHCPLIKIIPRPLTDPCIQKAFRDFHLFTHLIFTSKTSIH
CCEEEEECCCCHHCCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHH
LLHDHLSHFGLSLDDWKSKTSIAVGQVSGSHLRALGIQPALIAKEETAEGLIIELHPLSL
HHHHHHHHHCCCCHHCCCCCEEEEECCCCCEEEEECCCCCEEECCCCCCCEEEEEECCCC
QKASFFWPHSAQARSVLVDFFTDRHLNYYACPFYDTQFRQPEYIPSLEQFDEIVFTSPST
CCCEEECCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCHHHHHHEEECCCHH
VHAFAKIFGYFPIDKKYVTIGPITLQCLQTYIPQLNS
HHHHHHHHHCCCCCCCEEEECHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MRKILYTGLNPAHYHSTDQLTHCPLIKIIPRPLTDPCIQKAFRDFHLFTHLIFTSKTSIH
CCEEEEECCCCHHCCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHH
LLHDHLSHFGLSLDDWKSKTSIAVGQVSGSHLRALGIQPALIAKEETAEGLIIELHPLSL
HHHHHHHHHCCCCHHCCCCCEEEEECCCCCEEEEECCCCCEEECCCCCCCEEEEEECCCC
QKASFFWPHSAQARSVLVDFFTDRHLNYYACPFYDTQFRQPEYIPSLEQFDEIVFTSPST
CCCEEECCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCHHHHHHEEECCCHH
VHAFAKIFGYFPIDKKYVTIGPITLQCLQTYIPQLNS
HHHHHHHHHCCCCCCCEEEECHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA