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The map label for this gene is argS

Identifier: 46445865

GI number: 46445865

Start: 327625

End: 329379

Strand: Reverse

Name: argS

Synonym: pc0231

Alternate gene names: 46445865

Gene position: 329379-327625 (Counterclockwise)

Preceding gene: 46445876

Following gene: 46445861

Centisome position: 13.64

GC content: 37.44

Gene sequence:

>1755_bases
ATGAATACTCTTTTATCAGTTTTAGCAAATCTTTTTCAACAAGCCACAGCTAATGCGTTTCCAGATCTTTCTGTTTTGGA
TCCCAATTTTCAACCTGAAATCACTCCAAGTACTCAAGAAAAATTTGGCCATTATCAATTTAATTCCGCGATGAAGCTCG
CTAAGCTTCTTAAAAAAAATCCTAGACAAGTTGCAGAAGCTATTGTCAATCAATTAACCGACTCTTTGCCCCCCCTATCA
AAAATCGAAATTGCGGGGCCTGGTTTTATTAACATGACTTTTTCGACAGATTTTCTTTCTAAGAATCTCGATATTTTATT
ACGAGATGCTCATTTTGGAATTCCTTTTCCCGAAAAACCAGAAAAAATTATTATTGATTTTTCTTCTCCCAATGTTGCCA
AAGAAATGCATGTGGGACATCTTCGCTCAACAGTTATTGGAGATAGCCTCGCACGTCTATTTGAATTTCTGGGTCATCAT
GTTATTCGCCTCAATCACTTAGGAGATTGGGGAACAGCATTTGGAATGCTAATTGCCTATATGAAAGAAGAAGCTCCTAA
TGTTTTGTCCGGAGAACAAAAGACAGACTTGACTCATTTAGTGAGCTGGTATCGCTCTTCCAAAAAAAAATTTGATGAAG
AACCCGAATTTAAACGTCGTGCACAACTTGAAGTAGTAGCATTGCAACAAGGTGAACAAAAAGCTCGGGAAGCTTGGCAA
ATGATTTGCGAAATCTCCCAAAAAGCCTACCAAGAAATCTATCAACTTTTAGATGTCAAAATCATAGATCGAGGTGAATC
GTTTTACAATCCTTTTTTACCAAACATCGTCTCTGATTTAGAAAAAAAGGGATTAGTTAAAATTTCTGATGGGGCAAAAT
GTATTTTCTTAGAAGGGTTTCAAAATCGTGAAGGCGAAAATCTTCCTTTGATGATTCAAAAATCTGATGGGGGCTATAAT
TATGACACAACGGACATGGCGGCCATTTATCACCGCATTTATCATGAAAAAGGAGATCGCTTAATTTACATCACTGACGC
TGGGCAAGCTACCCATTTTCAAATGATTTTTAAAGCCGCCGAAAAGGCGAAGTATCTTGACACAACACAAATTCGAGTTG
ACCATGTCCCCTTTGGATTGGTTTTAGGAACAGATGGCAAGAAATTTAGAACTCGCTCTGGAGAAACTGAAAAATTAATC
GATCTTCTTAGGACAGCTATTAATTGCGCGGATAAAATTTTAAGTGAAAAAAATCCAGAAATGGAAGAATCGGAGAGACG
TCATCTAGCCAAATCACTTGGAATCGGAGCTATTAAATACGCGGATTTGTCTTGTAATCGCGTTGGAGATTATACATTTA
GTTACGATAGAATGCTTCGTTTTGAAGGAAATACGGCAGCTTTCTTAATGTATGCTTATGTGCGGATTGCTGGGATCAAA
CGTCGACTCAAAGCAAATCTTCCTGCTGTTTTAGAAAACACGCATATAAACTTAGAACACTCGACGGAAATTGAATTAGG
GCTCCATATACTACGTTTTCATGAAACACTAAATTTAATGGCTAATGATTTACTTCCTAATCGTTTAACAGATTATCTTT
ATACACTCGCAGAGAAATTCAATGCTTTTTTTAGAGATTGTCGCGTGGAAGGGACCCCTCAGCAAAACACACGCCTACTT
TTATGCGAAGCTACTGCCAAAGTTCTCAAACAAGGATTAACCATTCTTGGATTGACAACAGTTGATAAAATGTAG

Upstream 100 bases:

>100_bases
TTGGATATGTGTAAGTGACTTGAGAAATAATTCTACAACAGGCATGATCATCAAATTTCTAACTTCATTTCCGAATTAAC
TTAAAATTATCTTAACAATT

Downstream 100 bases:

>100_bases
AATTGAATGACTAAAATGATAATTGAATAGGTGTTTTGTGAGCTTCTCCAGCAATCTCTCTTACATAGCGAGGTATTGCA
TATCCAGATAAGCGTTTGGA

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 584; Mature: 584

Protein sequence:

>584_residues
MNTLLSVLANLFQQATANAFPDLSVLDPNFQPEITPSTQEKFGHYQFNSAMKLAKLLKKNPRQVAEAIVNQLTDSLPPLS
KIEIAGPGFINMTFSTDFLSKNLDILLRDAHFGIPFPEKPEKIIIDFSSPNVAKEMHVGHLRSTVIGDSLARLFEFLGHH
VIRLNHLGDWGTAFGMLIAYMKEEAPNVLSGEQKTDLTHLVSWYRSSKKKFDEEPEFKRRAQLEVVALQQGEQKAREAWQ
MICEISQKAYQEIYQLLDVKIIDRGESFYNPFLPNIVSDLEKKGLVKISDGAKCIFLEGFQNREGENLPLMIQKSDGGYN
YDTTDMAAIYHRIYHEKGDRLIYITDAGQATHFQMIFKAAEKAKYLDTTQIRVDHVPFGLVLGTDGKKFRTRSGETEKLI
DLLRTAINCADKILSEKNPEMEESERRHLAKSLGIGAIKYADLSCNRVGDYTFSYDRMLRFEGNTAAFLMYAYVRIAGIK
RRLKANLPAVLENTHINLEHSTEIELGLHILRFHETLNLMANDLLPNRLTDYLYTLAEKFNAFFRDCRVEGTPQQNTRLL
LCEATAKVLKQGLTILGLTTVDKM

Sequences:

>Translated_584_residues
MNTLLSVLANLFQQATANAFPDLSVLDPNFQPEITPSTQEKFGHYQFNSAMKLAKLLKKNPRQVAEAIVNQLTDSLPPLS
KIEIAGPGFINMTFSTDFLSKNLDILLRDAHFGIPFPEKPEKIIIDFSSPNVAKEMHVGHLRSTVIGDSLARLFEFLGHH
VIRLNHLGDWGTAFGMLIAYMKEEAPNVLSGEQKTDLTHLVSWYRSSKKKFDEEPEFKRRAQLEVVALQQGEQKAREAWQ
MICEISQKAYQEIYQLLDVKIIDRGESFYNPFLPNIVSDLEKKGLVKISDGAKCIFLEGFQNREGENLPLMIQKSDGGYN
YDTTDMAAIYHRIYHEKGDRLIYITDAGQATHFQMIFKAAEKAKYLDTTQIRVDHVPFGLVLGTDGKKFRTRSGETEKLI
DLLRTAINCADKILSEKNPEMEESERRHLAKSLGIGAIKYADLSCNRVGDYTFSYDRMLRFEGNTAAFLMYAYVRIAGIK
RRLKANLPAVLENTHINLEHSTEIELGLHILRFHETLNLMANDLLPNRLTDYLYTLAEKFNAFFRDCRVEGTPQQNTRLL
LCEATAKVLKQGLTILGLTTVDKM
>Mature_584_residues
MNTLLSVLANLFQQATANAFPDLSVLDPNFQPEITPSTQEKFGHYQFNSAMKLAKLLKKNPRQVAEAIVNQLTDSLPPLS
KIEIAGPGFINMTFSTDFLSKNLDILLRDAHFGIPFPEKPEKIIIDFSSPNVAKEMHVGHLRSTVIGDSLARLFEFLGHH
VIRLNHLGDWGTAFGMLIAYMKEEAPNVLSGEQKTDLTHLVSWYRSSKKKFDEEPEFKRRAQLEVVALQQGEQKAREAWQ
MICEISQKAYQEIYQLLDVKIIDRGESFYNPFLPNIVSDLEKKGLVKISDGAKCIFLEGFQNREGENLPLMIQKSDGGYN
YDTTDMAAIYHRIYHEKGDRLIYITDAGQATHFQMIFKAAEKAKYLDTTQIRVDHVPFGLVLGTDGKKFRTRSGETEKLI
DLLRTAINCADKILSEKNPEMEESERRHLAKSLGIGAIKYADLSCNRVGDYTFSYDRMLRFEGNTAAFLMYAYVRIAGIK
RRLKANLPAVLENTHINLEHSTEIELGLHILRFHETLNLMANDLLPNRLTDYLYTLAEKFNAFFRDCRVEGTPQQNTRLL
LCEATAKVLKQGLTILGLTTVDKM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=604, Percent_Identity=45.0331125827815, Blast_Score=494, Evalue=1e-140,
Organism=Homo sapiens, GI197100773, Length=484, Percent_Identity=34.0909090909091, Blast_Score=216, Evalue=3e-56,
Organism=Escherichia coli, GI1788184, Length=563, Percent_Identity=43.8721136767318, Blast_Score=459, Evalue=1e-130,
Organism=Caenorhabditis elegans, GI71985061, Length=603, Percent_Identity=41.4593698175788, Blast_Score=431, Evalue=1e-121,
Organism=Caenorhabditis elegans, GI71985068, Length=562, Percent_Identity=41.6370106761566, Blast_Score=414, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI17532153, Length=491, Percent_Identity=28.3095723014257, Blast_Score=164, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6320548, Length=551, Percent_Identity=29.94555353902, Blast_Score=202, Evalue=1e-52,
Organism=Saccharomyces cerevisiae, GI6321883, Length=550, Percent_Identity=27.2727272727273, Blast_Score=185, Evalue=2e-47,
Organism=Drosophila melanogaster, GI18859963, Length=595, Percent_Identity=44.3697478991597, Blast_Score=483, Evalue=1e-136,
Organism=Drosophila melanogaster, GI28571570, Length=483, Percent_Identity=29.6066252587992, Blast_Score=169, Evalue=7e-42,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_PARUW (Q6MEP4)

Other databases:

- EMBL:   BX908798
- RefSeq:   YP_007230.1
- ProteinModelPortal:   Q6MEP4
- SMR:   Q6MEP4
- STRING:   Q6MEP4
- GeneID:   2779797
- GenomeReviews:   BX908798_GR
- KEGG:   pcu:pc0231
- NMPDR:   fig|264201.1.peg.231
- eggNOG:   COG0018
- HOGENOM:   HBG695395
- OMA:   YNDDLQP
- PhylomeDB:   Q6MEP4
- ProtClustDB:   PRK01611
- BioCyc:   CPRO264201:PC0231-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 66382; Mature: 66382

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTLLSVLANLFQQATANAFPDLSVLDPNFQPEITPSTQEKFGHYQFNSAMKLAKLLKKN
CCHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHCC
PRQVAEAIVNQLTDSLPPLSKIEIAGPGFINMTFSTDFLSKNLDILLRDAHFGIPFPEKP
HHHHHHHHHHHHHHCCCCCCEEEECCCCEEEEEEEHHHHHCCCCEEEEECCCCCCCCCCC
EKIIIDFSSPNVAKEMHVGHLRSTVIGDSLARLFEFLGHHVIRLNHLGDWGTAFGMLIAY
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHH
MKEEAPNVLSGEQKTDLTHLVSWYRSSKKKFDEEPEFKRRAQLEVVALQQGEQKAREAWQ
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHEEEEEHHCCHHHHHHHHH
MICEISQKAYQEIYQLLDVKIIDRGESFYNPFLPNIVSDLEKKGLVKISDGAKCIFLEGF
HHHHHHHHHHHHHHHHHCEEEEECCCHHCCCCCHHHHHHHHHCCCEEECCCCEEEEEECC
QNREGENLPLMIQKSDGGYNYDTTDMAAIYHRIYHEKGDRLIYITDAGQATHFQMIFKAA
CCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHH
EKAKYLDTTQIRVDHVPFGLVLGTDGKKFRTRSGETEKLIDLLRTAINCADKILSEKNPE
HHHHCCCCCEEEEECCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
MEESERRHLAKSLGIGAIKYADLSCNRVGDYTFSYDRMLRFEGNTAAFLMYAYVRIAGIK
HHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEECHHHEEEECCCCHHHHHHHHHHHHHHH
RRLKANLPAVLENTHINLEHSTEIELGLHILRFHETLNLMANDLLPNRLTDYLYTLAEKF
HHHHCCCCHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
NAFFRDCRVEGTPQQNTRLLLCEATAKVLKQGLTILGLTTVDKM
HHHHHHCCCCCCCCCCCEEEEEHHHHHHHHCCCEEEEEECCCCC
>Mature Secondary Structure
MNTLLSVLANLFQQATANAFPDLSVLDPNFQPEITPSTQEKFGHYQFNSAMKLAKLLKKN
CCHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHCC
PRQVAEAIVNQLTDSLPPLSKIEIAGPGFINMTFSTDFLSKNLDILLRDAHFGIPFPEKP
HHHHHHHHHHHHHHCCCCCCEEEECCCCEEEEEEEHHHHHCCCCEEEEECCCCCCCCCCC
EKIIIDFSSPNVAKEMHVGHLRSTVIGDSLARLFEFLGHHVIRLNHLGDWGTAFGMLIAY
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHH
MKEEAPNVLSGEQKTDLTHLVSWYRSSKKKFDEEPEFKRRAQLEVVALQQGEQKAREAWQ
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHEEEEEHHCCHHHHHHHHH
MICEISQKAYQEIYQLLDVKIIDRGESFYNPFLPNIVSDLEKKGLVKISDGAKCIFLEGF
HHHHHHHHHHHHHHHHHCEEEEECCCHHCCCCCHHHHHHHHHCCCEEECCCCEEEEEECC
QNREGENLPLMIQKSDGGYNYDTTDMAAIYHRIYHEKGDRLIYITDAGQATHFQMIFKAA
CCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHH
EKAKYLDTTQIRVDHVPFGLVLGTDGKKFRTRSGETEKLIDLLRTAINCADKILSEKNPE
HHHHCCCCCEEEEECCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
MEESERRHLAKSLGIGAIKYADLSCNRVGDYTFSYDRMLRFEGNTAAFLMYAYVRIAGIK
HHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEECHHHEEEECCCCHHHHHHHHHHHHHHH
RRLKANLPAVLENTHINLEHSTEIELGLHILRFHETLNLMANDLLPNRLTDYLYTLAEKF
HHHHCCCCHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
NAFFRDCRVEGTPQQNTRLLLCEATAKVLKQGLTILGLTTVDKM
HHHHHHCCCCCCCCCCCEEEEEHHHHHHHHCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA