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The map label for this gene is murA

Identifier: 46445863

GI number: 46445863

Start: 325018

End: 326415

Strand: Direct

Name: murA

Synonym: pc0229

Alternate gene names: 46445863

Gene position: 325018-326415 (Clockwise)

Preceding gene: 46445862

Following gene: 46445864

Centisome position: 13.46

GC content: 39.84

Gene sequence:

>1398_bases
ATGGATGTGTTAAAAATTACAGGTGGGATTCCCTTAAAAGGGCAAGTCAAAGCTGCCGGAGCAAAAAATGCCATGACCAA
ATTGCTGGTCGCCTCTCTTTTATCTGATAAAAAATGCACTTTTTATAATGTTCCCAATATTGGGGATGTTGAAGTAACAG
TTTCACTTTGCCAAGAAATTGGCATGGAAGTGAGATGGGATCGCGCAGCAGGAATCATGGAAGTCATTACAAAAGAACTT
AAAACTTCCTATATTCCACAAAGATTTTCGGGATCTAATCGCATTCCTATTTTGATGATAGGGGCTTTATTAGGAAGAAC
AGACCAAGATATTATAGTTCCTACAGCTGGAGGATGTCCTATTGGACAACGGCCAGTGGATTTTCACATTCAAGCATTAG
AGCAGCTTGGAGCAGTCATTGAATATCGAGGAATGAAACGGGAAGGGGCCTACTTCGCGCATGCTCATAATGGTTTGAAA
GGAACGCTTATCACATTGCCTTATCCTTCAGTTGGGGCGACAGAAAATACGATTTTAGCCGGAATCACTGCACGGGGTGT
AACTGTCATTAAAAATGCTGCAATTGAACCTGAAATTGTTGAATTGATTCTCTTTTTACAAAAACTCGGAGCCATTATTA
CAATTGATGTCGATAGAACAATTCGAATTCAAGGTACTCGCCGTTTTTATGAAGTCGAACACACAGTTATTCCAGATCGA
ATTGAGGCAGCTTCTTGGGGTATGGCAGCGATTAGCTCAAAGGGAAAAGTGTTTGTAGAAGGGGCTCAGCATTTGAATAT
GATTACTTTTCTTAATAAGCTTCGAGAAGTAGGTGGAGGATTCGATGTTCGTAGCAATGGGATTGAATTTTTCTATGATG
GACCTTTACAAGGAGGCTTACATCTGGAAACAGATGTCCACCCAGGCTTTATGACAGATTGGCAGCAACCCTTTGTCGTT
TTATTAACGCAGTCTTCTGGCACATCTGTGGTTCATGAGACAGTTTATGAAAATCGTTTTGGCTATACAGATACTTTAAA
AGAAATGGGTGCTGATATTACCCCTTTTAGGCAGTGCCTGGGTGGTAAATCATGTCGATTTGCTTCACAAAGTTTTAGCC
ATAGTGCGATTATTAAAGGGGCAACACCATTAGTTGGAAAGGAAATTCGCATTCCAGATTTAAGAGCTGGTTTTGCTTAT
ATTATGGCAGCTTTAATTGCTAACGATACAAGTACAATTTCAGGACTTCCTTTTATTCAACGTGGTTACGAAAACTTTAT
TGGTAAATTAGCTGATCTTGGAGCCAATGTCAGTTTGGTTGAGGAAGAAAAAAACGTAAAAGAGATGCCTGAAAACTCCT
CCAAACTTCCTTTATTTGCCGAATTGCAGGTGAATTAA

Upstream 100 bases:

>100_bases
GACTTATAATAATTTATTATCCTTTTTATTCGGATTAATGACATTATTTCTAATAAATGATATAAGCTTGTTCTCAATTA
AAAAGTGATAGGTAATAGGG

Downstream 100 bases:

>100_bases
AATAAATGAATAGTTTGTCTTCAAACACTGGATGTTAAAAAAATCTAATAAACTTACGATAATTTAAAATCATTATTTTA
GAATTGTTAAATGCTATTTT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MDVLKITGGIPLKGQVKAAGAKNAMTKLLVASLLSDKKCTFYNVPNIGDVEVTVSLCQEIGMEVRWDRAAGIMEVITKEL
KTSYIPQRFSGSNRIPILMIGALLGRTDQDIIVPTAGGCPIGQRPVDFHIQALEQLGAVIEYRGMKREGAYFAHAHNGLK
GTLITLPYPSVGATENTILAGITARGVTVIKNAAIEPEIVELILFLQKLGAIITIDVDRTIRIQGTRRFYEVEHTVIPDR
IEAASWGMAAISSKGKVFVEGAQHLNMITFLNKLREVGGGFDVRSNGIEFFYDGPLQGGLHLETDVHPGFMTDWQQPFVV
LLTQSSGTSVVHETVYENRFGYTDTLKEMGADITPFRQCLGGKSCRFASQSFSHSAIIKGATPLVGKEIRIPDLRAGFAY
IMAALIANDTSTISGLPFIQRGYENFIGKLADLGANVSLVEEEKNVKEMPENSSKLPLFAELQVN

Sequences:

>Translated_465_residues
MDVLKITGGIPLKGQVKAAGAKNAMTKLLVASLLSDKKCTFYNVPNIGDVEVTVSLCQEIGMEVRWDRAAGIMEVITKEL
KTSYIPQRFSGSNRIPILMIGALLGRTDQDIIVPTAGGCPIGQRPVDFHIQALEQLGAVIEYRGMKREGAYFAHAHNGLK
GTLITLPYPSVGATENTILAGITARGVTVIKNAAIEPEIVELILFLQKLGAIITIDVDRTIRIQGTRRFYEVEHTVIPDR
IEAASWGMAAISSKGKVFVEGAQHLNMITFLNKLREVGGGFDVRSNGIEFFYDGPLQGGLHLETDVHPGFMTDWQQPFVV
LLTQSSGTSVVHETVYENRFGYTDTLKEMGADITPFRQCLGGKSCRFASQSFSHSAIIKGATPLVGKEIRIPDLRAGFAY
IMAALIANDTSTISGLPFIQRGYENFIGKLADLGANVSLVEEEKNVKEMPENSSKLPLFAELQVN
>Mature_465_residues
MDVLKITGGIPLKGQVKAAGAKNAMTKLLVASLLSDKKCTFYNVPNIGDVEVTVSLCQEIGMEVRWDRAAGIMEVITKEL
KTSYIPQRFSGSNRIPILMIGALLGRTDQDIIVPTAGGCPIGQRPVDFHIQALEQLGAVIEYRGMKREGAYFAHAHNGLK
GTLITLPYPSVGATENTILAGITARGVTVIKNAAIEPEIVELILFLQKLGAIITIDVDRTIRIQGTRRFYEVEHTVIPDR
IEAASWGMAAISSKGKVFVEGAQHLNMITFLNKLREVGGGFDVRSNGIEFFYDGPLQGGLHLETDVHPGFMTDWQQPFVV
LLTQSSGTSVVHETVYENRFGYTDTLKEMGADITPFRQCLGGKSCRFASQSFSHSAIIKGATPLVGKEIRIPDLRAGFAY
IMAALIANDTSTISGLPFIQRGYENFIGKLADLGANVSLVEEEKNVKEMPENSSKLPLFAELQVN

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=443, Percent_Identity=34.7629796839729, Blast_Score=230, Evalue=2e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_PARUW (Q6MEP6)

Other databases:

- EMBL:   BX908798
- RefSeq:   YP_007228.1
- ProteinModelPortal:   Q6MEP6
- SMR:   Q6MEP6
- STRING:   Q6MEP6
- GeneID:   2781162
- GenomeReviews:   BX908798_GR
- KEGG:   pcu:pc0229
- NMPDR:   fig|264201.1.peg.229
- eggNOG:   COG0766
- HOGENOM:   HBG482701
- OMA:   LVPKAMV
- ProtClustDB:   PRK09369
- BioCyc:   CPRO264201:PC0229-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 50688; Mature: 50688

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: ACT_SITE 119-119

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVLKITGGIPLKGQVKAAGAKNAMTKLLVASLLSDKKCTFYNVPNIGDVEVTVSLCQEI
CCEEEECCCCCCCCCEECCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHC
GMEVRWDRAAGIMEVITKELKTSYIPQRFSGSNRIPILMIGALLGRTDQDIIVPTAGGCP
CCEEEEHHHHHHHHHHHHHHHHHCCCHHCCCCCCCHHEEEEHHHCCCCCCEEEECCCCCC
IGQRPVDFHIQALEQLGAVIEYRGMKREGAYFAHAHNGLKGTLITLPYPSVGATENTILA
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEEECCCCCCCCCCEEEE
GITARGVTVIKNAAIEPEIVELILFLQKLGAIITIDVDRTIRIQGTRRFYEVEHTVIPDR
EEHHCCEEEECCCCCCHHHHHHHHHHHHCCCEEEEECCCEEEEECCCEEEEEECEECCCH
IEAASWGMAAISSKGKVFVEGAQHLNMITFLNKLREVGGGFDVRSNGIEFFYDGPLQGGL
HHHCCCCHHHHCCCCEEEEECHHHHHHHHHHHHHHHHCCCCEECCCCEEEEECCCCCCCE
HLETDVHPGFMTDWQQPFVVLLTQSSGTSVVHETVYENRFGYTDTLKEMGADITPFRQCL
EEECCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCHHHHHHCCCCCCHHHHHH
GGKSCRFASQSFSHSAIIKGATPLVGKEIRIPDLRAGFAYIMAALIANDTSTISGLPFIQ
CCCCCEECCCCCCCCEEECCCCCCCCCEECCCCCHHHHHHHHHHHHHCCCCCCCCCHHHH
RGYENFIGKLADLGANVSLVEEEKNVKEMPENSSKLPLFAELQVN
HHHHHHHHHHHHCCCCEEEEECHHHHHHCCCCCCCCCEEEEEEEC
>Mature Secondary Structure
MDVLKITGGIPLKGQVKAAGAKNAMTKLLVASLLSDKKCTFYNVPNIGDVEVTVSLCQEI
CCEEEECCCCCCCCCEECCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHC
GMEVRWDRAAGIMEVITKELKTSYIPQRFSGSNRIPILMIGALLGRTDQDIIVPTAGGCP
CCEEEEHHHHHHHHHHHHHHHHHCCCHHCCCCCCCHHEEEEHHHCCCCCCEEEECCCCCC
IGQRPVDFHIQALEQLGAVIEYRGMKREGAYFAHAHNGLKGTLITLPYPSVGATENTILA
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEEECCCCCCCCCCEEEE
GITARGVTVIKNAAIEPEIVELILFLQKLGAIITIDVDRTIRIQGTRRFYEVEHTVIPDR
EEHHCCEEEECCCCCCHHHHHHHHHHHHCCCEEEEECCCEEEEECCCEEEEEECEECCCH
IEAASWGMAAISSKGKVFVEGAQHLNMITFLNKLREVGGGFDVRSNGIEFFYDGPLQGGL
HHHCCCCHHHHCCCCEEEEECHHHHHHHHHHHHHHHHCCCCEECCCCEEEEECCCCCCCE
HLETDVHPGFMTDWQQPFVVLLTQSSGTSVVHETVYENRFGYTDTLKEMGADITPFRQCL
EEECCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCHHHHHHCCCCCCHHHHHH
GGKSCRFASQSFSHSAIIKGATPLVGKEIRIPDLRAGFAYIMAALIANDTSTISGLPFIQ
CCCCCEECCCCCCCCEEECCCCCCCCCEECCCCCHHHHHHHHHHHHHCCCCCCCCCHHHH
RGYENFIGKLADLGANVSLVEEEKNVKEMPENSSKLPLFAELQVN
HHHHHHHHHHHHCCCCEEEEECHHHHHHCCCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA