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The map label for this gene is yvgR [H]

Identifier: 46445860

GI number: 46445860

Start: 321638

End: 322792

Strand: Direct

Name: yvgR [H]

Synonym: pc0226

Alternate gene names: 46445860

Gene position: 321638-322792 (Clockwise)

Preceding gene: 46445859

Following gene: 46445862

Centisome position: 13.32

GC content: 34.81

Gene sequence:

>1155_bases
ATGAATTATTCTACATATAATAAACAAAATCCTTTTTTAGCTACGATTAGAAATCGATACCAACTATCAAAATCTGGATC
TCAAAAAAATACGCAACATCTTGTTCTTGATTTGCGAGGATCTCAGTTGACTTATGAAGCAGGGGATAGTATTGGAGTTT
ATCCCAAACATGATCCAGAACTTATTAATAAAACATTAATTGCAGCAAGAGCCAGTGGCGAGGAATACATTCAATCAAAA
CAAACTGGTGAAACAATTTCTTTAAGAGATTTCTTTTCTAAACAAGGAAATATCACGGACGTAAGTCAGAAACTCTTAAA
AGAGTTATATAATAGGCAAACAAATTTAGACAAAAAACACCAATTAGAACTGCTTTTAGATGAAAATAATCGAGTAGCAT
TGAAAGCGTACTTGGCTTTACATGAAGTTTGGGATTTATTATTATTTCATGTAGAAGTGCATTTCACTCCTCAAGAACTT
GCTGATTTGCTAATGCCTCTTTTACCCCGTTTTTACTCTATTTCTTCTTCTCAGAAATATGTGGGAGAAGAGGTGCACTT
AACAATTGCTCATTTAGAATATGAAACAAATGGTCATAAAAGAAGGGGAGTTTGTACTCATTATCTATGTGAATTAGTGA
AATTGCATAATCCTGAGGTTCCTGTTTTTATTCAGCCTTCTCACAGTTTTAGATTACCTGAAGATTTACACGCTCCTCTT
GTCATGGTTGGACCTGGAACAGGTGTTGCTCCTTTCCGGGCATTTTTACAAGAACGGGTACTGCACCACCAAACCAAAGG
AAAACACTGGCTGTTTTTTGGTGAAAGGAATCGCTCTTCAGATTTCTTTTACGAAGAAGATTGGCGATTATTTGAACAAC
ATGGACATTTACGATTAGATGCTGTTTTTTCGAGAGATCAGGAAGAAAAAGTTTATGTTCAACATAAGATGTTTGAACAT
GGGGAAGAGTTATTTAAATGGCTTGAAGAAGGGGCTTATCTTTTTGTTTGTGGTGATGCAGAGAGAATGGCAAAGGATGT
TGAGATAACTCTCCTTGCAATTATTCAAGAATTTGGTAAAAAAGATTTTCAAGAAGCTCGTGAATATGTGAAACGCCTAC
GGCAACAAAAAAAATATTTAAGAGATGTGTATTAA

Upstream 100 bases:

>100_bases
CAGCTGCGGCAGAAGATTTTCTGGTGAAGTATTTAGGTGGAAGAAGTGAGCCCGCCTCTTCAGCCGAAGATTGGAAAACT
CTTAGAAAATAAAGGATTTT

Downstream 100 bases:

>100_bases
CGTTTTGATCGGGACTATTTTAAAGTAGTGATTCAAGATTTTATTTTATGACTGTTTCAGGGTATTTTTTAAATATCGGA
GCATTTGATGAACATTTCTT

Product: putative sulfite reductase (NADPH) flavoprotein

Products: NA

Alternate protein names: SiR-FP [H]

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MNYSTYNKQNPFLATIRNRYQLSKSGSQKNTQHLVLDLRGSQLTYEAGDSIGVYPKHDPELINKTLIAARASGEEYIQSK
QTGETISLRDFFSKQGNITDVSQKLLKELYNRQTNLDKKHQLELLLDENNRVALKAYLALHEVWDLLLFHVEVHFTPQEL
ADLLMPLLPRFYSISSSQKYVGEEVHLTIAHLEYETNGHKRRGVCTHYLCELVKLHNPEVPVFIQPSHSFRLPEDLHAPL
VMVGPGTGVAPFRAFLQERVLHHQTKGKHWLFFGERNRSSDFFYEEDWRLFEQHGHLRLDAVFSRDQEEKVYVQHKMFEH
GEELFKWLEEGAYLFVCGDAERMAKDVEITLLAIIQEFGKKDFQEAREYVKRLRQQKKYLRDVY

Sequences:

>Translated_384_residues
MNYSTYNKQNPFLATIRNRYQLSKSGSQKNTQHLVLDLRGSQLTYEAGDSIGVYPKHDPELINKTLIAARASGEEYIQSK
QTGETISLRDFFSKQGNITDVSQKLLKELYNRQTNLDKKHQLELLLDENNRVALKAYLALHEVWDLLLFHVEVHFTPQEL
ADLLMPLLPRFYSISSSQKYVGEEVHLTIAHLEYETNGHKRRGVCTHYLCELVKLHNPEVPVFIQPSHSFRLPEDLHAPL
VMVGPGTGVAPFRAFLQERVLHHQTKGKHWLFFGERNRSSDFFYEEDWRLFEQHGHLRLDAVFSRDQEEKVYVQHKMFEH
GEELFKWLEEGAYLFVCGDAERMAKDVEITLLAIIQEFGKKDFQEAREYVKRLRQQKKYLRDVY
>Mature_384_residues
MNYSTYNKQNPFLATIRNRYQLSKSGSQKNTQHLVLDLRGSQLTYEAGDSIGVYPKHDPELINKTLIAARASGEEYIQSK
QTGETISLRDFFSKQGNITDVSQKLLKELYNRQTNLDKKHQLELLLDENNRVALKAYLALHEVWDLLLFHVEVHFTPQEL
ADLLMPLLPRFYSISSSQKYVGEEVHLTIAHLEYETNGHKRRGVCTHYLCELVKLHNPEVPVFIQPSHSFRLPEDLHAPL
VMVGPGTGVAPFRAFLQERVLHHQTKGKHWLFFGERNRSSDFFYEEDWRLFEQHGHLRLDAVFSRDQEEKVYVQHKMFEH
GEELFKWLEEGAYLFVCGDAERMAKDVEITLLAIIQEFGKKDFQEAREYVKRLRQQKKYLRDVY

Specific function: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow f

COG id: COG0369

COG function: function code P; Sulfite reductase, alpha subunit (flavoprotein)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 flavodoxin-like domain [H]

Homologues:

Organism=Homo sapiens, GI127139033, Length=408, Percent_Identity=32.5980392156863, Blast_Score=188, Evalue=7e-48,
Organism=Homo sapiens, GI7657393, Length=401, Percent_Identity=29.1770573566085, Blast_Score=173, Evalue=2e-43,
Organism=Homo sapiens, GI221316709, Length=401, Percent_Identity=29.1770573566085, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI221316705, Length=410, Percent_Identity=28.5365853658537, Blast_Score=165, Evalue=5e-41,
Organism=Homo sapiens, GI24041029, Length=415, Percent_Identity=31.3253012048193, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI221316707, Length=358, Percent_Identity=28.4916201117318, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI40254422, Length=405, Percent_Identity=31.8518518518519, Blast_Score=138, Evalue=8e-33,
Organism=Homo sapiens, GI169790956, Length=424, Percent_Identity=28.7735849056604, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI169790958, Length=424, Percent_Identity=28.7735849056604, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI10835173, Length=424, Percent_Identity=29.4811320754717, Blast_Score=132, Evalue=8e-31,
Organism=Escherichia coli, GI1789123, Length=382, Percent_Identity=37.696335078534, Blast_Score=270, Evalue=1e-73,
Organism=Caenorhabditis elegans, GI17554134, Length=399, Percent_Identity=30.3258145363409, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17566446, Length=351, Percent_Identity=28.2051282051282, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17531441, Length=259, Percent_Identity=30.1158301158301, Blast_Score=88, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6321832, Length=442, Percent_Identity=28.5067873303167, Blast_Score=152, Evalue=7e-38,
Organism=Saccharomyces cerevisiae, GI6321143, Length=409, Percent_Identity=26.161369193154, Blast_Score=130, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6325305, Length=243, Percent_Identity=28.8065843621399, Blast_Score=104, Evalue=3e-23,
Organism=Drosophila melanogaster, GI17137192, Length=405, Percent_Identity=33.0864197530864, Blast_Score=193, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24582192, Length=405, Percent_Identity=33.0864197530864, Blast_Score=193, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24583543, Length=382, Percent_Identity=31.151832460733, Blast_Score=155, Evalue=5e-38,
Organism=Drosophila melanogaster, GI78706876, Length=382, Percent_Identity=31.151832460733, Blast_Score=155, Evalue=5e-38,
Organism=Drosophila melanogaster, GI78706872, Length=382, Percent_Identity=31.151832460733, Blast_Score=155, Evalue=5e-38,
Organism=Drosophila melanogaster, GI24660907, Length=242, Percent_Identity=33.4710743801653, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24660903, Length=242, Percent_Identity=33.4710743801653, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24647438, Length=405, Percent_Identity=23.9506172839506, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010199
- InterPro:   IPR003097
- InterPro:   IPR017927
- InterPro:   IPR001094
- InterPro:   IPR008254
- InterPro:   IPR001709
- InterPro:   IPR023173
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00667 FAD_binding_1; PF00258 Flavodoxin_1; PF00175 NAD_binding_1 [H]

EC number: =1.8.1.2 [H]

Molecular weight: Translated: 45068; Mature: 45068

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYSTYNKQNPFLATIRNRYQLSKSGSQKNTQHLVLDLRGSQLTYEAGDSIGVYPKHDPE
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEEECCCEEEEECCCCCCCCCCCCHH
LINKTLIAARASGEEYIQSKQTGETISLRDFFSKQGNITDVSQKLLKELYNRQTNLDKKH
HHHHHHHHHHCCCHHHHHHHCCCCEEEHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHH
QLELLLDENNRVALKAYLALHEVWDLLLFHVEVHFTPQELADLLMPLLPRFYSISSSQKY
EEEEEEECCCCEEHHHHHHHHHHHHHHHHHHEEEECHHHHHHHHHHHHHHHHCCCCCHHH
VGEEVHLTIAHLEYETNGHKRRGVCTHYLCELVKLHNPEVPVFIQPSHSFRLPEDLHAPL
CCCEEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHHCCCE
VMVGPGTGVAPFRAFLQERVLHHQTKGKHWLFFGERNRSSDFFYEEDWRLFEQHGHLRLD
EEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCEEEE
AVFSRDQEEKVYVQHKMFEHGEELFKWLEEGAYLFVCGDAERMAKDVEITLLAIIQEFGK
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHCH
KDFQEAREYVKRLRQQKKYLRDVY
HHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNYSTYNKQNPFLATIRNRYQLSKSGSQKNTQHLVLDLRGSQLTYEAGDSIGVYPKHDPE
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEEECCCEEEEECCCCCCCCCCCCHH
LINKTLIAARASGEEYIQSKQTGETISLRDFFSKQGNITDVSQKLLKELYNRQTNLDKKH
HHHHHHHHHHCCCHHHHHHHCCCCEEEHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHH
QLELLLDENNRVALKAYLALHEVWDLLLFHVEVHFTPQELADLLMPLLPRFYSISSSQKY
EEEEEEECCCCEEHHHHHHHHHHHHHHHHHHEEEECHHHHHHHHHHHHHHHHCCCCCHHH
VGEEVHLTIAHLEYETNGHKRRGVCTHYLCELVKLHNPEVPVFIQPSHSFRLPEDLHAPL
CCCEEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHHCCCE
VMVGPGTGVAPFRAFLQERVLHHQTKGKHWLFFGERNRSSDFFYEEDWRLFEQHGHLRLD
EEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCEEEE
AVFSRDQEEKVYVQHKMFEHGEELFKWLEEGAYLFVCGDAERMAKDVEITLLAIIQEFGK
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHCH
KDFQEAREYVKRLRQQKKYLRDVY
HHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]