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The map label for this gene is putA [H]

Identifier: 46445667

GI number: 46445667

Start: 48362

End: 52009

Strand: Direct

Name: putA [H]

Synonym: pc0033

Alternate gene names: 46445667

Gene position: 48362-52009 (Clockwise)

Preceding gene: 46445662

Following gene: 46445668

Centisome position: 2.0

GC content: 36.95

Gene sequence:

>3648_bases
TTGATTGAAAATGCCTTATTTCAAATTCATTCAGTCAAAGGAAAAAAACTTTCATTACAAGAAAGGCAAGATCTGGCGAT
TTCGTTAGCAGCTAAAATGTTAAAAGAGGCGCAATATATTCAAACAAAAGTTGAAAAAAGGCAACAAGCAGAACTTGCTG
GAATGATGAACGATTCCGTTGGTAAGATTTTTACAACCGTCTTAACAGACCAGTGTTTTAGAAGTCTTCAAAATAGTAGA
GTGGCTGATCAGCTTGCGCAAGTCATTCACAAATATGGAATCCCCATCTACTTATCGGATAAAAAACGACTAGCCTTAAA
AGCTTTTAGCCTAGTTGGTAAAATTCTCTCTTCTTTAGCAGTTCCTATTACTATTCGACTGATTCAGAAAGAAACAAGGC
ATATTATTTTACCAGGAGAGCCTCAAGCGTTTGCTAAACACATGAAAAAGAGGTGTCAAGAGGGAGTAAGAATTAATCTT
AATCATCTAGGTGAAGCAATTTTAGGAGAAGATGAAGCCAGGCGTCGTTTGCAAATTTATCTGGATGATTTAGCAAATCC
TTTGATCGAGTATATTTCTATTAAAATTTCTACTATTTATAGCCAAATCCATTTACTGGCTTGGGAAGAAACGTTAGAAA
TTTTATCTGAAAGACTTCGCTTATTGTATCGAGCAGCAATTAAAAATAAATATAGACGAGCAACGGGTGAAGTCATATCG
AAATTTGTTAATTTAGATATGGAAGAATATCGAGACTTAAACCTAACAGTCGCACTTTTTAAAAAAGTTTTAGATGAGCC
TGAGTTTTTTCAATATCAAGGCGGAATTGTTTTGCAAAGCTATTTACCCGATTCCTTTTTAATTCAACAAGAGCTAACGC
AGTGGGCGATGCAAAGAGTTAATCGGATGGGAGCTCCTATCAAAATCCGCCTTGTAAAAGGTGCTAATTTAGCGATGGAG
CAATTTGAATCCGCTGTTCGTTTATGGCCACAGGCTCCTTACACAACTAAAGCAGATGTAGATGCAAATTATAAACGAAT
GGTCACGTATGGATGCGAGTTTCAACGTGCTCAGGCAGCTCATTTAGGGATTGCTAGTCATAATTTATTTGATATCGCTT
ATGCTTTATTACTCCGTTCTGAAAATCACGTTGAAAAAGAAGTCTGCTTTGAAATGCTGGAGGGAATGGCTGATCATATT
CGACGAGTTGTTCAAACTTTAGCAGATGACATGCTTCTTTACTGCCCAACTGCCACTAAAGAAGAATTTCAAAGCGCCGT
TGCTTATCTTGTCAGACGTTTAGATGAAAATACAGCTCCTGAAAACTTCTTACGACATGCTTTTGATTTAAGGCCTGGCA
CTGATGATTGGAATAATCAAGTTCATTTGTTTAAACAAGCTTGTCAAAATTACGAACAAGTTTCCGATCAACCTAGGCGT
TTACAAAATAGATTGCATAAAGATCGTTTGCTCAATCAACGAAAATGTTTCCAAAATGTGGCAGATACTGACTGGTCATT
ATCTCACAATCGCCAATGGGCGAAAATAATTATTGATCAATGGAAAAATAAAAAACATCCAGATGTTCCTTTAGTCATTA
ATGGCTTCCACTATACTTCAGAAAATCGCTGGGGAATTGGAGAAGATCCCTCTTTTCCTGGAAAAATTTTGTATCGCTAT
GCGTTAGCTTCCAAAGAACAAGTTGATGAAGCTTTAGACGCTGCCCAAAATGCTTATTTAAAATGGTCTGCGACAACTTC
TCAAGAACGGGCCAATTTATTAATAAAAATAGCGCAAGGTTTAGAGCTGCATCGTGCTGATTTGATTGGAGCTATGATTG
CTGATACGGCTAAAACATTGATTGAAGCAGATATAGAAGTTTCCGAAGCGATCGATTTTGCTAATTATTATCGCTTCAAT
TTATTAGAATGGATGTATTTGGAAGATGTCAAGTGGAGTGCTAAAGGTGTTGTTGTCATTGCTCCTCCTTGGAATTTTCC
ATGTTCGATAGCGGCTGGCGGTATTTTAGCAGCATTAGTTACTGGCAATACGGTAATTTTAAAACCTGCTTTTGAGTCTG
TTTTAGTTTGTTGGCATTTAGCTCAAATTTTTTGGGAGGCGGGAATTAGCCAGCAAGTGTTACAATTTGTTGTTTGCGAA
GATGAACCTGTGGGAAGCGCCTTAATTCAAGATTCTCGAGTGAATGCAGTTGTCTTAACTGGTGCGACAGAAACTGCAAA
ACTTTTTTTACGCTTAAGGGCAGATTTGGATTTAATGGCCGAAACGGGTGGTAAAAACACAATGATTATAACCTCTATGG
CTGATCGTGATTTAGCGATTAAAGATTTGGTTCAATCGGCGTTTAGTCATGCAGGACAAAAATGTAGCGCATGTAGTTTG
GCTATTGTAGAAGCAGAGACTTATGATAATCTTCACTTTCGTCAGCAATTAAAAGATTCTGTAGAAAGTTTATCAATCGG
TTCCCCGTGGAAATTAAAATCTAAAGTTAATCCTTTAATTCGTGAAGCTAACCCCAATCTGTTACGTGGTTTAACGCAGT
TAGAGGAAGGGGAAGAATGGCTTGTACAACCTAAGCAAGATCCTCAAAATCCTTATCTGTGGAGTCCGGGAATTAAGCTT
GGTGTAAAACCAGGGAATTTTACCTATAATACAGAGTTATTTGGACCTGTTTTGGGGCTTGTAAGAGCAGAAAATTTCGA
TGAAGCCTTACACATGATGAATCAAACAGGCTACGGTTTAACAGCAGGTATTCATACCCTAGATGAAAGAGAGCAGAAGC
AATGGTTTCAAAAAATAGAGGCAGGGAATTGTTATATTAATAGGACTATGACAGGAGCTATTGTTGAAAGACAACCATTT
GGAGGGTGTAAAGAAAGCAGTTTTGGAAAAGGATCGAAAGCTGGAGGTCCTAATTATCTAGTGCAGTTTATGCAAACTTC
TCAAAAAAACTTACCTACAGAGCAAAAAGAGTTAAAAGAAATGCCTCTGGCATTTCTAAAAAATGTTCAGAGACTAAAGT
ATTTGAGTTCCGAAGAATATGAAATTTTTAGTTTAAGTATGAAAAATTATGCTTTCTATTATGATTTATATTTTTCTCGA
TCTCATGATCCTAGTTTAGTTAGAGGGCAAGATAATTTACAAACTTATCGCCCGCATAATCAAATTTCGGTTAGGGTACA
ATCACCTGATCGTTTAGTAGACTTATTACGTTTGATAGCAGCCTCTATTATTTGTTCTACCCCTTTAATGTTGAGTACAG
ATAATCAAGAGACTTACCAAAAATTCCAGTCTTTACGTTTACCTCCTTTCATTTCTTTTAAATTGGAGGCTGAATCGACC
TTTATCGAAAGATTAGAGCGAGGTGAGATCAAAAGAATGCGTGTGTTAAGCCCTTTCTCTAAATCTTTAGAAAATACTTT
AGCGAATGCAGCTTGTCATTTAAATAGAGGGGAAGTAATGGCCAATGGACGATTAGAACTTCTTCATTTTTTAAGAGAAG
TAAGTTTAAGTTTTGATTATCACAGGTATGGAAACCTTGCCGAGCGAGAAAAAGAATATAGACATCCATTACCCGGTCAT
AAAGGAAAAACCTGTTTACCTTGTGGAGCTTGTTGTTGTGATGGATAA

Upstream 100 bases:

>100_bases
TTAAAGAGATAAGTTTGTTATAAAGAGCGCTTGGTTTTGCGTTGCAAAAGGATCAATTAATCCTCTATCAAACCTGGGTT
AGAACATGAAAAAGTCTTCT

Downstream 100 bases:

>100_bases
TTTATTTAATTTAAATAAAGAGCAAAAAGATGCTGTGACAACCTTAGAAGGTCCAGTATTAGTATTAGCGGGGGCGGGAT
CTGGAAAAACGCGTGTTGTT

Product: putative bifunctional protein (proline dehydrogenase and delta-1-pyrroline-5-carboxylate dehydrogenase)

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1215; Mature: 1215

Protein sequence:

>1215_residues
MIENALFQIHSVKGKKLSLQERQDLAISLAAKMLKEAQYIQTKVEKRQQAELAGMMNDSVGKIFTTVLTDQCFRSLQNSR
VADQLAQVIHKYGIPIYLSDKKRLALKAFSLVGKILSSLAVPITIRLIQKETRHIILPGEPQAFAKHMKKRCQEGVRINL
NHLGEAILGEDEARRRLQIYLDDLANPLIEYISIKISTIYSQIHLLAWEETLEILSERLRLLYRAAIKNKYRRATGEVIS
KFVNLDMEEYRDLNLTVALFKKVLDEPEFFQYQGGIVLQSYLPDSFLIQQELTQWAMQRVNRMGAPIKIRLVKGANLAME
QFESAVRLWPQAPYTTKADVDANYKRMVTYGCEFQRAQAAHLGIASHNLFDIAYALLLRSENHVEKEVCFEMLEGMADHI
RRVVQTLADDMLLYCPTATKEEFQSAVAYLVRRLDENTAPENFLRHAFDLRPGTDDWNNQVHLFKQACQNYEQVSDQPRR
LQNRLHKDRLLNQRKCFQNVADTDWSLSHNRQWAKIIIDQWKNKKHPDVPLVINGFHYTSENRWGIGEDPSFPGKILYRY
ALASKEQVDEALDAAQNAYLKWSATTSQERANLLIKIAQGLELHRADLIGAMIADTAKTLIEADIEVSEAIDFANYYRFN
LLEWMYLEDVKWSAKGVVVIAPPWNFPCSIAAGGILAALVTGNTVILKPAFESVLVCWHLAQIFWEAGISQQVLQFVVCE
DEPVGSALIQDSRVNAVVLTGATETAKLFLRLRADLDLMAETGGKNTMIITSMADRDLAIKDLVQSAFSHAGQKCSACSL
AIVEAETYDNLHFRQQLKDSVESLSIGSPWKLKSKVNPLIREANPNLLRGLTQLEEGEEWLVQPKQDPQNPYLWSPGIKL
GVKPGNFTYNTELFGPVLGLVRAENFDEALHMMNQTGYGLTAGIHTLDEREQKQWFQKIEAGNCYINRTMTGAIVERQPF
GGCKESSFGKGSKAGGPNYLVQFMQTSQKNLPTEQKELKEMPLAFLKNVQRLKYLSSEEYEIFSLSMKNYAFYYDLYFSR
SHDPSLVRGQDNLQTYRPHNQISVRVQSPDRLVDLLRLIAASIICSTPLMLSTDNQETYQKFQSLRLPPFISFKLEAEST
FIERLERGEIKRMRVLSPFSKSLENTLANAACHLNRGEVMANGRLELLHFLREVSLSFDYHRYGNLAEREKEYRHPLPGH
KGKTCLPCGACCCDG

Sequences:

>Translated_1215_residues
MIENALFQIHSVKGKKLSLQERQDLAISLAAKMLKEAQYIQTKVEKRQQAELAGMMNDSVGKIFTTVLTDQCFRSLQNSR
VADQLAQVIHKYGIPIYLSDKKRLALKAFSLVGKILSSLAVPITIRLIQKETRHIILPGEPQAFAKHMKKRCQEGVRINL
NHLGEAILGEDEARRRLQIYLDDLANPLIEYISIKISTIYSQIHLLAWEETLEILSERLRLLYRAAIKNKYRRATGEVIS
KFVNLDMEEYRDLNLTVALFKKVLDEPEFFQYQGGIVLQSYLPDSFLIQQELTQWAMQRVNRMGAPIKIRLVKGANLAME
QFESAVRLWPQAPYTTKADVDANYKRMVTYGCEFQRAQAAHLGIASHNLFDIAYALLLRSENHVEKEVCFEMLEGMADHI
RRVVQTLADDMLLYCPTATKEEFQSAVAYLVRRLDENTAPENFLRHAFDLRPGTDDWNNQVHLFKQACQNYEQVSDQPRR
LQNRLHKDRLLNQRKCFQNVADTDWSLSHNRQWAKIIIDQWKNKKHPDVPLVINGFHYTSENRWGIGEDPSFPGKILYRY
ALASKEQVDEALDAAQNAYLKWSATTSQERANLLIKIAQGLELHRADLIGAMIADTAKTLIEADIEVSEAIDFANYYRFN
LLEWMYLEDVKWSAKGVVVIAPPWNFPCSIAAGGILAALVTGNTVILKPAFESVLVCWHLAQIFWEAGISQQVLQFVVCE
DEPVGSALIQDSRVNAVVLTGATETAKLFLRLRADLDLMAETGGKNTMIITSMADRDLAIKDLVQSAFSHAGQKCSACSL
AIVEAETYDNLHFRQQLKDSVESLSIGSPWKLKSKVNPLIREANPNLLRGLTQLEEGEEWLVQPKQDPQNPYLWSPGIKL
GVKPGNFTYNTELFGPVLGLVRAENFDEALHMMNQTGYGLTAGIHTLDEREQKQWFQKIEAGNCYINRTMTGAIVERQPF
GGCKESSFGKGSKAGGPNYLVQFMQTSQKNLPTEQKELKEMPLAFLKNVQRLKYLSSEEYEIFSLSMKNYAFYYDLYFSR
SHDPSLVRGQDNLQTYRPHNQISVRVQSPDRLVDLLRLIAASIICSTPLMLSTDNQETYQKFQSLRLPPFISFKLEAEST
FIERLERGEIKRMRVLSPFSKSLENTLANAACHLNRGEVMANGRLELLHFLREVSLSFDYHRYGNLAEREKEYRHPLPGH
KGKTCLPCGACCCDG
>Mature_1215_residues
MIENALFQIHSVKGKKLSLQERQDLAISLAAKMLKEAQYIQTKVEKRQQAELAGMMNDSVGKIFTTVLTDQCFRSLQNSR
VADQLAQVIHKYGIPIYLSDKKRLALKAFSLVGKILSSLAVPITIRLIQKETRHIILPGEPQAFAKHMKKRCQEGVRINL
NHLGEAILGEDEARRRLQIYLDDLANPLIEYISIKISTIYSQIHLLAWEETLEILSERLRLLYRAAIKNKYRRATGEVIS
KFVNLDMEEYRDLNLTVALFKKVLDEPEFFQYQGGIVLQSYLPDSFLIQQELTQWAMQRVNRMGAPIKIRLVKGANLAME
QFESAVRLWPQAPYTTKADVDANYKRMVTYGCEFQRAQAAHLGIASHNLFDIAYALLLRSENHVEKEVCFEMLEGMADHI
RRVVQTLADDMLLYCPTATKEEFQSAVAYLVRRLDENTAPENFLRHAFDLRPGTDDWNNQVHLFKQACQNYEQVSDQPRR
LQNRLHKDRLLNQRKCFQNVADTDWSLSHNRQWAKIIIDQWKNKKHPDVPLVINGFHYTSENRWGIGEDPSFPGKILYRY
ALASKEQVDEALDAAQNAYLKWSATTSQERANLLIKIAQGLELHRADLIGAMIADTAKTLIEADIEVSEAIDFANYYRFN
LLEWMYLEDVKWSAKGVVVIAPPWNFPCSIAAGGILAALVTGNTVILKPAFESVLVCWHLAQIFWEAGISQQVLQFVVCE
DEPVGSALIQDSRVNAVVLTGATETAKLFLRLRADLDLMAETGGKNTMIITSMADRDLAIKDLVQSAFSHAGQKCSACSL
AIVEAETYDNLHFRQQLKDSVESLSIGSPWKLKSKVNPLIREANPNLLRGLTQLEEGEEWLVQPKQDPQNPYLWSPGIKL
GVKPGNFTYNTELFGPVLGLVRAENFDEALHMMNQTGYGLTAGIHTLDEREQKQWFQKIEAGNCYINRTMTGAIVERQPF
GGCKESSFGKGSKAGGPNYLVQFMQTSQKNLPTEQKELKEMPLAFLKNVQRLKYLSSEEYEIFSLSMKNYAFYYDLYFSR
SHDPSLVRGQDNLQTYRPHNQISVRVQSPDRLVDLLRLIAASIICSTPLMLSTDNQETYQKFQSLRLPPFISFKLEAEST
FIERLERGEIKRMRVLSPFSKSLENTLANAACHLNRGEVMANGRLELLHFLREVSLSFDYHRYGNLAEREKEYRHPLPGH
KGKTCLPCGACCCDG

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG1012

COG function: function code C; NAD-dependent aldehyde dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI238859541, Length=502, Percent_Identity=27.0916334661355, Blast_Score=153, Evalue=8e-37,
Organism=Homo sapiens, GI25777736, Length=502, Percent_Identity=27.0916334661355, Blast_Score=153, Evalue=1e-36,
Organism=Homo sapiens, GI25777734, Length=502, Percent_Identity=27.0916334661355, Blast_Score=153, Evalue=1e-36,
Organism=Homo sapiens, GI25777730, Length=473, Percent_Identity=26.8498942917548, Blast_Score=152, Evalue=2e-36,
Organism=Homo sapiens, GI115387104, Length=438, Percent_Identity=26.027397260274, Blast_Score=142, Evalue=3e-33,
Organism=Homo sapiens, GI153266822, Length=437, Percent_Identity=28.3752860411899, Blast_Score=141, Evalue=4e-33,
Organism=Homo sapiens, GI12007648, Length=449, Percent_Identity=26.0579064587973, Blast_Score=139, Evalue=2e-32,
Organism=Homo sapiens, GI25777732, Length=436, Percent_Identity=26.8348623853211, Blast_Score=137, Evalue=6e-32,
Organism=Homo sapiens, GI25777724, Length=426, Percent_Identity=27.6995305164319, Blast_Score=131, Evalue=3e-30,
Organism=Homo sapiens, GI21361176, Length=426, Percent_Identity=26.9953051643192, Blast_Score=128, Evalue=3e-29,
Organism=Homo sapiens, GI25777728, Length=399, Percent_Identity=27.5689223057644, Blast_Score=123, Evalue=1e-27,
Organism=Homo sapiens, GI21614513, Length=415, Percent_Identity=25.7831325301205, Blast_Score=122, Evalue=2e-27,
Organism=Homo sapiens, GI238814322, Length=322, Percent_Identity=27.3291925465839, Blast_Score=117, Evalue=7e-26,
Organism=Homo sapiens, GI4507229, Length=437, Percent_Identity=25.4004576659039, Blast_Score=112, Evalue=2e-24,
Organism=Homo sapiens, GI11095441, Length=443, Percent_Identity=23.9277652370203, Blast_Score=112, Evalue=2e-24,
Organism=Homo sapiens, GI25952152, Length=439, Percent_Identity=24.6013667425968, Blast_Score=112, Evalue=3e-24,
Organism=Homo sapiens, GI25777726, Length=423, Percent_Identity=26.241134751773, Blast_Score=107, Evalue=1e-22,
Organism=Homo sapiens, GI25777721, Length=450, Percent_Identity=24.6666666666667, Blast_Score=104, Evalue=6e-22,
Organism=Homo sapiens, GI188035924, Length=470, Percent_Identity=24.2553191489362, Blast_Score=103, Evalue=1e-21,
Organism=Homo sapiens, GI310128103, Length=456, Percent_Identity=24.1228070175439, Blast_Score=100, Evalue=6e-21,
Organism=Homo sapiens, GI310128093, Length=443, Percent_Identity=23.9277652370203, Blast_Score=99, Evalue=2e-20,
Organism=Homo sapiens, GI206597441, Length=419, Percent_Identity=23.3890214797136, Blast_Score=94, Evalue=1e-18,
Organism=Homo sapiens, GI206597439, Length=419, Percent_Identity=23.3890214797136, Blast_Score=94, Evalue=1e-18,
Organism=Homo sapiens, GI22907049, Length=419, Percent_Identity=23.3890214797136, Blast_Score=94, Evalue=1e-18,
Organism=Homo sapiens, GI73466520, Length=381, Percent_Identity=23.0971128608924, Blast_Score=89, Evalue=3e-17,
Organism=Homo sapiens, GI4557303, Length=381, Percent_Identity=23.0971128608924, Blast_Score=88, Evalue=4e-17,
Organism=Homo sapiens, GI310128091, Length=384, Percent_Identity=24.7395833333333, Blast_Score=87, Evalue=8e-17,
Organism=Homo sapiens, GI301500698, Length=263, Percent_Identity=26.2357414448669, Blast_Score=80, Evalue=1e-14,
Organism=Homo sapiens, GI310128089, Length=334, Percent_Identity=24.251497005988, Blast_Score=79, Evalue=4e-14,
Organism=Homo sapiens, GI4502043, Length=421, Percent_Identity=22.0902612826603, Blast_Score=77, Evalue=1e-13,
Organism=Homo sapiens, GI238814371, Length=421, Percent_Identity=22.0902612826603, Blast_Score=77, Evalue=1e-13,
Organism=Homo sapiens, GI71773324, Length=317, Percent_Identity=23.3438485804416, Blast_Score=75, Evalue=4e-13,
Organism=Homo sapiens, GI310128087, Length=260, Percent_Identity=24.6153846153846, Blast_Score=72, Evalue=3e-12,
Organism=Homo sapiens, GI310128097, Length=255, Percent_Identity=25.8823529411765, Blast_Score=67, Evalue=8e-11,
Organism=Homo sapiens, GI73695881, Length=317, Percent_Identity=22.0820189274448, Blast_Score=67, Evalue=8e-11,
Organism=Homo sapiens, GI73695879, Length=317, Percent_Identity=22.0820189274448, Blast_Score=67, Evalue=8e-11,
Organism=Escherichia coli, GI1787250, Length=829, Percent_Identity=30.2774427020507, Blast_Score=285, Evalue=2e-77,
Organism=Escherichia coli, GI87081896, Length=489, Percent_Identity=28.0163599182004, Blast_Score=150, Evalue=4e-37,
Organism=Escherichia coli, GI1787684, Length=455, Percent_Identity=28.5714285714286, Blast_Score=145, Evalue=1e-35,
Organism=Escherichia coli, GI1788042, Length=458, Percent_Identity=29.6943231441048, Blast_Score=140, Evalue=7e-34,
Organism=Escherichia coli, GI87081926, Length=431, Percent_Identity=25.754060324826, Blast_Score=138, Evalue=2e-33,
Organism=Escherichia coli, GI1789015, Length=444, Percent_Identity=28.6036036036036, Blast_Score=134, Evalue=3e-32,
Organism=Escherichia coli, GI1787558, Length=458, Percent_Identity=27.5109170305677, Blast_Score=132, Evalue=2e-31,
Organism=Escherichia coli, GI1786504, Length=437, Percent_Identity=27.6887871853547, Blast_Score=123, Evalue=8e-29,
Organism=Escherichia coli, GI87082295, Length=445, Percent_Identity=26.9662921348315, Blast_Score=120, Evalue=4e-28,
Organism=Escherichia coli, GI1787715, Length=461, Percent_Identity=27.3318872017354, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI25143876, Length=455, Percent_Identity=28.3516483516484, Blast_Score=155, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI25143874, Length=455, Percent_Identity=28.3516483516484, Blast_Score=155, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17562198, Length=435, Percent_Identity=28.0459770114943, Blast_Score=149, Evalue=8e-36,
Organism=Caenorhabditis elegans, GI25144435, Length=437, Percent_Identity=27.9176201372998, Blast_Score=141, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17551164, Length=447, Percent_Identity=26.3982102908277, Blast_Score=140, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17534447, Length=464, Percent_Identity=27.801724137931, Blast_Score=139, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI133930964, Length=444, Percent_Identity=26.3513513513513, Blast_Score=128, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI32564736, Length=341, Percent_Identity=27.8592375366569, Blast_Score=126, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI115534176, Length=453, Percent_Identity=25.8278145695364, Blast_Score=122, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI71986308, Length=405, Percent_Identity=24.4444444444444, Blast_Score=117, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI115532534, Length=396, Percent_Identity=27.5252525252525, Blast_Score=113, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI32564151, Length=412, Percent_Identity=26.2135922330097, Blast_Score=108, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17534119, Length=449, Percent_Identity=23.8307349665924, Blast_Score=108, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71995606, Length=440, Percent_Identity=23.1818181818182, Blast_Score=103, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI71990744, Length=275, Percent_Identity=30.5454545454545, Blast_Score=100, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI25146391, Length=413, Percent_Identity=24.455205811138, Blast_Score=99, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI32566756, Length=413, Percent_Identity=24.455205811138, Blast_Score=99, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI25146394, Length=413, Percent_Identity=24.455205811138, Blast_Score=99, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71995613, Length=396, Percent_Identity=22.979797979798, Blast_Score=89, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17564084, Length=428, Percent_Identity=22.4299065420561, Blast_Score=88, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6323821, Length=450, Percent_Identity=28.2222222222222, Blast_Score=155, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6320917, Length=448, Percent_Identity=28.7946428571429, Blast_Score=154, Evalue=7e-38,
Organism=Saccharomyces cerevisiae, GI6323822, Length=439, Percent_Identity=26.879271070615, Blast_Score=144, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6321826, Length=530, Percent_Identity=27.5471698113208, Blast_Score=140, Evalue=9e-34,
Organism=Saccharomyces cerevisiae, GI6325196, Length=476, Percent_Identity=26.890756302521, Blast_Score=139, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6324950, Length=444, Percent_Identity=25.9009009009009, Blast_Score=134, Evalue=6e-32,
Organism=Saccharomyces cerevisiae, GI6319478, Length=486, Percent_Identity=25.1028806584362, Blast_Score=108, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6321828, Length=494, Percent_Identity=22.6720647773279, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI281362580, Length=448, Percent_Identity=28.3482142857143, Blast_Score=167, Evalue=6e-41,
Organism=Drosophila melanogaster, GI62472918, Length=448, Percent_Identity=28.3482142857143, Blast_Score=167, Evalue=6e-41,
Organism=Drosophila melanogaster, GI62472926, Length=448, Percent_Identity=28.3482142857143, Blast_Score=167, Evalue=6e-41,
Organism=Drosophila melanogaster, GI62472936, Length=448, Percent_Identity=28.3482142857143, Blast_Score=167, Evalue=6e-41,
Organism=Drosophila melanogaster, GI21356737, Length=448, Percent_Identity=28.3482142857143, Blast_Score=167, Evalue=6e-41,
Organism=Drosophila melanogaster, GI24668425, Length=489, Percent_Identity=28.0163599182004, Blast_Score=152, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24668417, Length=489, Percent_Identity=28.0163599182004, Blast_Score=152, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24668413, Length=489, Percent_Identity=28.0163599182004, Blast_Score=152, Evalue=2e-36,
Organism=Drosophila melanogaster, GI20129399, Length=428, Percent_Identity=28.7383177570093, Blast_Score=147, Evalue=5e-35,
Organism=Drosophila melanogaster, GI24585660, Length=481, Percent_Identity=26.6112266112266, Blast_Score=138, Evalue=2e-32,
Organism=Drosophila melanogaster, GI28571798, Length=487, Percent_Identity=25.4620123203285, Blast_Score=136, Evalue=9e-32,
Organism=Drosophila melanogaster, GI28571796, Length=487, Percent_Identity=25.4620123203285, Blast_Score=136, Evalue=9e-32,
Organism=Drosophila melanogaster, GI28571794, Length=487, Percent_Identity=25.4620123203285, Blast_Score=136, Evalue=9e-32,
Organism=Drosophila melanogaster, GI28571806, Length=487, Percent_Identity=25.4620123203285, Blast_Score=136, Evalue=1e-31,
Organism=Drosophila melanogaster, GI28571802, Length=487, Percent_Identity=25.4620123203285, Blast_Score=136, Evalue=1e-31,
Organism=Drosophila melanogaster, GI28571800, Length=487, Percent_Identity=25.4620123203285, Blast_Score=136, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24650465, Length=435, Percent_Identity=26.4367816091954, Blast_Score=133, Evalue=6e-31,
Organism=Drosophila melanogaster, GI24638876, Length=442, Percent_Identity=23.3031674208145, Blast_Score=102, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24638878, Length=442, Percent_Identity=23.3031674208145, Blast_Score=102, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24666674, Length=449, Percent_Identity=24.0534521158129, Blast_Score=95, Evalue=3e-19,
Organism=Drosophila melanogaster, GI28574525, Length=453, Percent_Identity=22.5165562913907, Blast_Score=92, Evalue=2e-18,
Organism=Drosophila melanogaster, GI281360299, Length=421, Percent_Identity=23.9904988123515, Blast_Score=80, Evalue=8e-15,
Organism=Drosophila melanogaster, GI281360297, Length=421, Percent_Identity=23.9904988123515, Blast_Score=80, Evalue=8e-15,
Organism=Drosophila melanogaster, GI281360295, Length=421, Percent_Identity=23.9904988123515, Blast_Score=80, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24586250, Length=421, Percent_Identity=23.9904988123515, Blast_Score=80, Evalue=8e-15,
Organism=Drosophila melanogaster, GI281360301, Length=421, Percent_Identity=23.9904988123515, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI45552499, Length=421, Percent_Identity=23.5154394299287, Blast_Score=77, Evalue=9e-14,
Organism=Drosophila melanogaster, GI281360303, Length=421, Percent_Identity=23.5154394299287, Blast_Score=76, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 138436; Mature: 138436

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU ; PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIENALFQIHSVKGKKLSLQERQDLAISLAAKMLKEAQYIQTKVEKRQQAELAGMMNDSV
CCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
GKIFTTVLTDQCFRSLQNSRVADQLAQVIHKYGIPIYLSDKKRLALKAFSLVGKILSSLA
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHH
VPITIRLIQKETRHIILPGEPQAFAKHMKKRCQEGVRINLNHLGEAILGEDEARRRLQIY
HHHHHEEEECCCCEEEECCCHHHHHHHHHHHHHCCCEEEHHHHCHHHCCCHHHHHHHHHH
LDDLANPLIEYISIKISTIYSQIHLLAWEETLEILSERLRLLYRAAIKNKYRRATGEVIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KFVNLDMEEYRDLNLTVALFKKVLDEPEFFQYQGGIVLQSYLPDSFLIQQELTQWAMQRV
HHHCCCHHHHCCCCHHHHHHHHHHCCCCCEEECCCEEEECCCCCHHHHHHHHHHHHHHHH
NRMGAPIKIRLVKGANLAMEQFESAVRLWPQAPYTTKADVDANYKRMVTYGCEFQRAQAA
HHCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHEEECCCHHHHHHH
HLGIASHNLFDIAYALLLRSENHVEKEVCFEMLEGMADHIRRVVQTLADDMLLYCPTATK
HCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCH
EEFQSAVAYLVRRLDENTAPENFLRHAFDLRPGTDDWNNQVHLFKQACQNYEQVSDQPRR
HHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHH
LQNRLHKDRLLNQRKCFQNVADTDWSLSHNRQWAKIIIDQWKNKKHPDVPLVINGFHYTS
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEECEEECC
ENRWGIGEDPSFPGKILYRYALASKEQVDEALDAAQNAYLKWSATTSQERANLLIKIAQG
CCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHCC
LELHRADLIGAMIADTAKTLIEADIEVSEAIDFANYYRFNLLEWMYLEDVKWSAKGVVVI
CHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
APPWNFPCSIAAGGILAALVTGNTVILKPAFESVLVCWHLAQIFWEAGISQQVLQFVVCE
ECCCCCCCHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCC
DEPVGSALIQDSRVNAVVLTGATETAKLFLRLRADLDLMAETGGKNTMIITSMADRDLAI
CCCCCHHHHCCCCCCEEEEECCCHHHHHHHHHHCCHHHHHCCCCCCEEEEEECCCCCHHH
KDLVQSAFSHAGQKCSACSLAIVEAETYDNLHFRQQLKDSVESLSIGSPWKLKSKVNPLI
HHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCEEHHHCCHHH
REANPNLLRGLTQLEEGEEWLVQPKQDPQNPYLWSPGIKLGVKPGNFTYNTELFGPVLGL
HCCCCHHHHHHHHHHCCCHHCCCCCCCCCCCEEECCCCEEECCCCCEEECHHHHHHHHHH
VRAENFDEALHMMNQTGYGLTAGIHTLDEREQKQWFQKIEAGNCYINRTMTGAIVERQPF
HHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEECCEEECCCC
GGCKESSFGKGSKAGGPNYLVQFMQTSQKNLPTEQKELKEMPLAFLKNVQRLKYLSSEEY
CCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCCC
EIFSLSMKNYAFYYDLYFSRSHDPSLVRGQDNLQTYRPHNQISVRVQSPDRLVDLLRLIA
EEEEEEECCEEEEEEEEEECCCCCCCCCCCCCCHHCCCCCEEEEEECCHHHHHHHHHHHH
ASIICSTPLMLSTDNQETYQKFQSLRLPPFISFKLEAESTFIERLERGEIKRMRVLSPFS
HHHHHCCCCEEECCCHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHCCHHHHHHHHHHH
KSLENTLANAACHLNRGEVMANGRLELLHFLREVSLSFDYHRYGNLAEREKEYRHPLPGH
HHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHCCCCCCC
KGKTCLPCGACCCDG
CCCCCCCCCCCCCCC
>Mature Secondary Structure
MIENALFQIHSVKGKKLSLQERQDLAISLAAKMLKEAQYIQTKVEKRQQAELAGMMNDSV
CCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
GKIFTTVLTDQCFRSLQNSRVADQLAQVIHKYGIPIYLSDKKRLALKAFSLVGKILSSLA
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHH
VPITIRLIQKETRHIILPGEPQAFAKHMKKRCQEGVRINLNHLGEAILGEDEARRRLQIY
HHHHHEEEECCCCEEEECCCHHHHHHHHHHHHHCCCEEEHHHHCHHHCCCHHHHHHHHHH
LDDLANPLIEYISIKISTIYSQIHLLAWEETLEILSERLRLLYRAAIKNKYRRATGEVIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KFVNLDMEEYRDLNLTVALFKKVLDEPEFFQYQGGIVLQSYLPDSFLIQQELTQWAMQRV
HHHCCCHHHHCCCCHHHHHHHHHHCCCCCEEECCCEEEECCCCCHHHHHHHHHHHHHHHH
NRMGAPIKIRLVKGANLAMEQFESAVRLWPQAPYTTKADVDANYKRMVTYGCEFQRAQAA
HHCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHEEECCCHHHHHHH
HLGIASHNLFDIAYALLLRSENHVEKEVCFEMLEGMADHIRRVVQTLADDMLLYCPTATK
HCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCH
EEFQSAVAYLVRRLDENTAPENFLRHAFDLRPGTDDWNNQVHLFKQACQNYEQVSDQPRR
HHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHH
LQNRLHKDRLLNQRKCFQNVADTDWSLSHNRQWAKIIIDQWKNKKHPDVPLVINGFHYTS
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEECEEECC
ENRWGIGEDPSFPGKILYRYALASKEQVDEALDAAQNAYLKWSATTSQERANLLIKIAQG
CCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHCC
LELHRADLIGAMIADTAKTLIEADIEVSEAIDFANYYRFNLLEWMYLEDVKWSAKGVVVI
CHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
APPWNFPCSIAAGGILAALVTGNTVILKPAFESVLVCWHLAQIFWEAGISQQVLQFVVCE
ECCCCCCCHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCC
DEPVGSALIQDSRVNAVVLTGATETAKLFLRLRADLDLMAETGGKNTMIITSMADRDLAI
CCCCCHHHHCCCCCCEEEEECCCHHHHHHHHHHCCHHHHHCCCCCCEEEEEECCCCCHHH
KDLVQSAFSHAGQKCSACSLAIVEAETYDNLHFRQQLKDSVESLSIGSPWKLKSKVNPLI
HHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCEEHHHCCHHH
REANPNLLRGLTQLEEGEEWLVQPKQDPQNPYLWSPGIKLGVKPGNFTYNTELFGPVLGL
HCCCCHHHHHHHHHHCCCHHCCCCCCCCCCCEEECCCCEEECCCCCEEECHHHHHHHHHH
VRAENFDEALHMMNQTGYGLTAGIHTLDEREQKQWFQKIEAGNCYINRTMTGAIVERQPF
HHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEECCEEECCCC
GGCKESSFGKGSKAGGPNYLVQFMQTSQKNLPTEQKELKEMPLAFLKNVQRLKYLSSEEY
CCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCCC
EIFSLSMKNYAFYYDLYFSRSHDPSLVRGQDNLQTYRPHNQISVRVQSPDRLVDLLRLIA
EEEEEEECCEEEEEEEEEECCCCCCCCCCCCCCHHCCCCCEEEEEECCHHHHHHHHHHHH
ASIICSTPLMLSTDNQETYQKFQSLRLPPFISFKLEAESTFIERLERGEIKRMRVLSPFS
HHHHHCCCCEEECCCHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHCCHHHHHHHHHHH
KSLENTLANAACHLNRGEVMANGRLELLHFLREVSLSFDYHRYGNLAEREKEYRHPLPGH
HHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHCCCCCCC
KGKTCLPCGACCCDG
CCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]