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The map label for this gene is groEs [H]

Identifier: 46445665

GI number: 46445665

Start: 46386

End: 46733

Strand: Reverse

Name: groEs [H]

Synonym: pc0031

Alternate gene names: 46445665

Gene position: 46733-46386 (Counterclockwise)

Preceding gene: 46445666

Following gene: 46445664

Centisome position: 1.94

GC content: 37.36

Gene sequence:

>348_bases
ATGCTTTTTTTCAGAGTCAATAAAACAGATGAAAATAACAGGAGAATAGACATGACAACTAAGACTAAAATTAAACCTTT
GGGAGATCGCGTTGTAGTTCAACGAGCAAAAGCTGCTACTTCAAAAGGCGGCATTCTTCTTCCTGATTCAGCGCAAGAAA
AACCAAGAGAAGGACATGTCATTGCCGCAGGTCCTGGTAAAATGAGTGAAAGCGGACAACTTGAACCTATTTCTGTTAAA
GTTGGTGATCGCATTCTTTTTGGAGCCTACGCTGGTACAGAGGTTAAAGATAATGATGAAGATTATTTAATCTTATCCGA
AAACGATATTCTAGGAATTTTATCTTAA

Upstream 100 bases:

>100_bases
CCTCTATTGAACCCTTCCATTTAGCAAAACTAGCAATTACAACAAGTAACTGCTAAAATTTTATTTCAGCTCCTTGACAT
AAATCGTTTTCAATCCTAAA

Downstream 100 bases:

>100_bases
TCTTTTTAATGCAAGGACCCGTTTATGGCAAAATTATTACAATTTAACGAAGAAGCCTTAAAATCAATCTTAAAAGGTGT
AAAAACGCTTGCTAAAGCCG

Product: chaperonin groES

Products: NA

Alternate protein names: GroES protein 1; Protein Cpn10 1 [H]

Number of amino acids: Translated: 115; Mature: 115

Protein sequence:

>115_residues
MLFFRVNKTDENNRRIDMTTKTKIKPLGDRVVVQRAKAATSKGGILLPDSAQEKPREGHVIAAGPGKMSESGQLEPISVK
VGDRILFGAYAGTEVKDNDEDYLILSENDILGILS

Sequences:

>Translated_115_residues
MLFFRVNKTDENNRRIDMTTKTKIKPLGDRVVVQRAKAATSKGGILLPDSAQEKPREGHVIAAGPGKMSESGQLEPISVK
VGDRILFGAYAGTEVKDNDEDYLILSENDILGILS
>Mature_115_residues
MLFFRVNKTDENNRRIDMTTKTKIKPLGDRVVVQRAKAATSKGGILLPDSAQEKPREGHVIAAGPGKMSESGQLEPISVK
VGDRILFGAYAGTEVKDNDEDYLILSENDILGILS

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter [H]

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family [H]

Homologues:

Organism=Homo sapiens, GI4504523, Length=91, Percent_Identity=46.1538461538462, Blast_Score=77, Evalue=2e-15,
Organism=Homo sapiens, GI169210012, Length=93, Percent_Identity=40.8602150537634, Blast_Score=71, Evalue=2e-13,
Organism=Homo sapiens, GI310125356, Length=94, Percent_Identity=40.4255319148936, Blast_Score=63, Evalue=5e-11,
Organism=Homo sapiens, GI239752758, Length=94, Percent_Identity=40.4255319148936, Blast_Score=63, Evalue=5e-11,
Organism=Homo sapiens, GI310118571, Length=94, Percent_Identity=40.4255319148936, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1790585, Length=93, Percent_Identity=45.1612903225806, Blast_Score=76, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17555568, Length=102, Percent_Identity=46.078431372549, Blast_Score=85, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6324594, Length=97, Percent_Identity=36.0824742268041, Blast_Score=60, Evalue=7e-11,
Organism=Drosophila melanogaster, GI21356029, Length=96, Percent_Identity=43.75, Blast_Score=71, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21358317, Length=95, Percent_Identity=40, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032 [H]

Pfam domain/function: PF00166 Cpn10 [H]

EC number: NA

Molecular weight: Translated: 12557; Mature: 12557

Theoretical pI: Translated: 7.54; Mature: 7.54

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFFRVNKTDENNRRIDMTTKTKIKPLGDRVVVQRAKAATSKGGILLPDSAQEKPREGHV
CEEEEECCCCCCCEEEEEEECCEEEECCCCEEEEHHHCCCCCCCEECCCCCCCCCCCCCE
IAAGPGKMSESGQLEPISVKVGDRILFGAYAGTEVKDNDEDYLILSENDILGILS
EEECCCCCCCCCCCCEEEEEECCEEEEEEECCCCCCCCCCCEEEECCCCEEEEEC
>Mature Secondary Structure
MLFFRVNKTDENNRRIDMTTKTKIKPLGDRVVVQRAKAATSKGGILLPDSAQEKPREGHV
CEEEEECCCCCCCEEEEEEECCEEEECCCCEEEEHHHCCCCCCCEECCCCCCCCCCCCCE
IAAGPGKMSESGQLEPISVKVGDRILFGAYAGTEVKDNDEDYLILSENDILGILS
EEECCCCCCCCCCCCEEEEEECCEEEEEEECCCCCCCCCCCEEEECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA