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The map label for this gene is cdd

Identifier: 45659288

GI number: 45659288

Start: 4247499

End: 4248104

Strand: Direct

Name: cdd

Synonym: LIC13472

Alternate gene names: 45659288

Gene position: 4247499-4248104 (Clockwise)

Preceding gene: 45659287

Following gene: 45659289

Centisome position: 99.31

GC content: 29.7

Gene sequence:

>606_bases
ATGAGCAAATCTCCAAGCGATCAGAATTTATCTGGAAAAAAATCAGATTCGGATCAAAAAAAAGTCAAAACTGAATTCTT
GATTAGTAAAAACATAGAATCAGATTCTATAACTTTCCAACTTTCCACAAAAGAAGATTCAGTCATTAGAACTGATAATA
AGATTTTATCCGATTTCTTAAATAAGTTGGAAAATTTAGTAACACGATACAGAGAAGAAATTCCAAGTTTTACTAGAATC
TATCATAAAGAAAAATTAATTTCAGAGACATTTAACGAAGTAGAAAAAAAATCAGACTCATCTTTTCATAGCGAGATTCT
TTGTATTCGAAACGCAAAAGAAAAATTAAAAACTCGTTATCTTGCAGATTGTATGCTTATTACATCTTTGGAACCATGTT
TGATGTGTGCAGGTACTATTCTTCTTTCCAGAATTCCAAAAGTGGTTTATCTTTTACCAGCAAAACAAGGAGAAGGGATT
TCTTCTCTGAGTATCGAAATGATTTATTCCCGAAATTTTTTTCCGGAACTATTTTGTATTCCAACTGAAATTTCTAAAAA
TGCTTTCAAATCGTTTTTCAAAGTCAGAAGAAAGAAATTCAATTGA

Upstream 100 bases:

>100_bases
TTTAAAAATCTGTCTCGAAATATTAAAAGAAATCATTTTAAATTTTTTAATAGAATACAATAGTTACTATAAATTACACG
TATAACAAAATTAGAATTAC

Downstream 100 bases:

>100_bases
CGTAAAACATTTCGACGGAATTCCTGAAAGCTACAGGAGAAGTGTCAGAGTGGTCTATTGTGCATGCTTGGAAAGCATGT
GTGCCAAAAGCACCCCGGGT

Product: cytidine deaminase

Products: uracil; NH3

Alternate protein names: NA

Number of amino acids: Translated: 201; Mature: 200

Protein sequence:

>201_residues
MSKSPSDQNLSGKKSDSDQKKVKTEFLISKNIESDSITFQLSTKEDSVIRTDNKILSDFLNKLENLVTRYREEIPSFTRI
YHKEKLISETFNEVEKKSDSSFHSEILCIRNAKEKLKTRYLADCMLITSLEPCLMCAGTILLSRIPKVVYLLPAKQGEGI
SSLSIEMIYSRNFFPELFCIPTEISKNAFKSFFKVRRKKFN

Sequences:

>Translated_201_residues
MSKSPSDQNLSGKKSDSDQKKVKTEFLISKNIESDSITFQLSTKEDSVIRTDNKILSDFLNKLENLVTRYREEIPSFTRI
YHKEKLISETFNEVEKKSDSSFHSEILCIRNAKEKLKTRYLADCMLITSLEPCLMCAGTILLSRIPKVVYLLPAKQGEGI
SSLSIEMIYSRNFFPELFCIPTEISKNAFKSFFKVRRKKFN
>Mature_200_residues
SKSPSDQNLSGKKSDSDQKKVKTEFLISKNIESDSITFQLSTKEDSVIRTDNKILSDFLNKLENLVTRYREEIPSFTRIY
HKEKLISETFNEVEKKSDSSFHSEILCIRNAKEKLKTRYLADCMLITSLEPCLMCAGTILLSRIPKVVYLLPAKQGEGIS
SLSIEMIYSRNFFPELFCIPTEISKNAFKSFFKVRRKKFN

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: 3.5.4.1

Molecular weight: Translated: 23218; Mature: 23087

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKSPSDQNLSGKKSDSDQKKVKTEFLISKNIESDSITFQLSTKEDSVIRTDNKILSDFL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHH
NKLENLVTRYREEIPSFTRIYHKEKLISETFNEVEKKSDSSFHSEILCIRNAKEKLKTRY
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LADCMLITSLEPCLMCAGTILLSRIPKVVYLLPAKQGEGISSLSIEMIYSRNFFPELFCI
HHHHHHHHCCCHHHHHHHHHHHHHHCHHEEEEECCCCCCCCHHHHEEEECCCCCCHHEEE
PTEISKNAFKSFFKVRRKKFN
CCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SKSPSDQNLSGKKSDSDQKKVKTEFLISKNIESDSITFQLSTKEDSVIRTDNKILSDFL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHH
NKLENLVTRYREEIPSFTRIYHKEKLISETFNEVEKKSDSSFHSEILCIRNAKEKLKTRY
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LADCMLITSLEPCLMCAGTILLSRIPKVVYLLPAKQGEGISSLSIEMIYSRNFFPELFCI
HHHHHHHHCCCHHHHHHHHHHHHHHCHHEEEEECCCCCCCCHHHHEEEECCCCCCHHEEE
PTEISKNAFKSFFKVRRKKFN
CCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: cytosine; H2O

Specific reaction: cytosine + H2O = uracil + NH3

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]