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The map label for this gene is argJ

Identifier: 45659092

GI number: 45659092

Start: 4010128

End: 4011285

Strand: Direct

Name: argJ

Synonym: LIC13271

Alternate gene names: 45659092

Gene position: 4010128-4011285 (Clockwise)

Preceding gene: 45659091

Following gene: 45659093

Centisome position: 93.76

GC content: 37.22

Gene sequence:

>1158_bases
ATGCACATGCCTAAAGGATTTTTATCTTTTGGAATTAATATCGGTATCAAGGACGATACAAAGGATTTTGGAGTTATTTA
TTCCGAAATCCCGTGTAAGGCGACTGCTGTGTTTACCAAAAACAATTTTCCAGGAGCTCCAGTGATTGTTGGCAAAGAAC
ACGTTCGGTCCGGAGTTCTTCAGGCAATTGTTATCAATTCTAAAAACTCGAACGTTGCAACTGGCGAAAAAGGAATTCAA
AATTCAAGAGAAATTTGTAAGATAATTGGAGAATCTCTTGATATCAAAGAAACGTTAGTCCTTCCTTCGTCTACTGGTGT
AATCGGAGTTCCTCTGAAAATGGAAATCATTCTGCCAGCTTGCAAAAAAGCGAAATCCCTTTTAAAACCGGGCAACTTGG
AAGAAGTCGCCGAGGCGATTATGACAACGGATACTAGAAAAAAAATTTCTTCCCGAAATATTAAAACGAAATCAGGACAA
GGAACAATTTACGGAATCGCAAAAGGCGCCGGTATGATTGAACCAAATATGGCGACTATGCTTTGTTATATTCTTTCGGA
TGTTTCGCTTCCAGAAGGAACTGATCTATATTCTATTTTAAAATCTTCGGTTGATCAAAGTTTCAATTGTTTAACAATTG
ATTCGGATACTTCAACGTCTGATACGGTTGCATTACTCTGTAACGGTTTATCCGGAGAAAGTAGTGTTCAAGATTTTTCT
AAAGCGCTTACTGAAATTTGTATCGATCTTACCAAACTGATTGCAACTGATGGGGAAGGTGCAACGAAACTGATTGAGCT
TACTATCTCAGGAGCTAAAAGTGAAGCCCAAGCAAGAAAAATCGGGAAGTCTATTTTAAATTCTCCTTTGGTTAAAACTG
CAATTTATGGCGGAGATCCTAACTGGGGAAGATTGATTATGGCGGTTGGCAAAGTTTTTGACGAACCCATTCCGTTCGAA
GGTCTTCAGATTTATTTCGGAACACTTCCGGTCAAAGAAGCCAATCCGGAAACTTTAAAAAAGCTTTCTGAATATTTAAA
AAATAATACTGAAATTTCTTTAAATGTAGTGTTGAATGTTGGGACGATTTCCATGAAATTTTGGGGTTGTGATTTTACAG
AAAAATATATAGAAGAAAATGCTTACTATACAACCTGA

Upstream 100 bases:

>100_bases
TTCCCACTCGTTATCAGACCGAAACATCCTGAATTTATTCTTTTCGACAGAGATAATTTTCTAAATATAGATCCAATCGA
CTCGCTCAAGGGATCTACTC

Downstream 100 bases:

>100_bases
AAGCAAAAATACCAATAGTGGATTTAAAGAAACATTCCGTTCTTTAGTTACGGATTATTATCTCATTTCCACAATCATCA
ATCTATTCGCAAAAGGAAGT

Product: bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein

Products: NA

Alternate protein names: Glutamate N-acetyltransferase; Ornithine acetyltransferase; OATase; Ornithine transacetylase; Amino-acid acetyltransferase; N-acetylglutamate synthase; AGS

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MHMPKGFLSFGINIGIKDDTKDFGVIYSEIPCKATAVFTKNNFPGAPVIVGKEHVRSGVLQAIVINSKNSNVATGEKGIQ
NSREICKIIGESLDIKETLVLPSSTGVIGVPLKMEIILPACKKAKSLLKPGNLEEVAEAIMTTDTRKKISSRNIKTKSGQ
GTIYGIAKGAGMIEPNMATMLCYILSDVSLPEGTDLYSILKSSVDQSFNCLTIDSDTSTSDTVALLCNGLSGESSVQDFS
KALTEICIDLTKLIATDGEGATKLIELTISGAKSEAQARKIGKSILNSPLVKTAIYGGDPNWGRLIMAVGKVFDEPIPFE
GLQIYFGTLPVKEANPETLKKLSEYLKNNTEISLNVVLNVGTISMKFWGCDFTEKYIEENAYYTT

Sequences:

>Translated_385_residues
MHMPKGFLSFGINIGIKDDTKDFGVIYSEIPCKATAVFTKNNFPGAPVIVGKEHVRSGVLQAIVINSKNSNVATGEKGIQ
NSREICKIIGESLDIKETLVLPSSTGVIGVPLKMEIILPACKKAKSLLKPGNLEEVAEAIMTTDTRKKISSRNIKTKSGQ
GTIYGIAKGAGMIEPNMATMLCYILSDVSLPEGTDLYSILKSSVDQSFNCLTIDSDTSTSDTVALLCNGLSGESSVQDFS
KALTEICIDLTKLIATDGEGATKLIELTISGAKSEAQARKIGKSILNSPLVKTAIYGGDPNWGRLIMAVGKVFDEPIPFE
GLQIYFGTLPVKEANPETLKKLSEYLKNNTEISLNVVLNVGTISMKFWGCDFTEKYIEENAYYTT
>Mature_385_residues
MHMPKGFLSFGINIGIKDDTKDFGVIYSEIPCKATAVFTKNNFPGAPVIVGKEHVRSGVLQAIVINSKNSNVATGEKGIQ
NSREICKIIGESLDIKETLVLPSSTGVIGVPLKMEIILPACKKAKSLLKPGNLEEVAEAIMTTDTRKKISSRNIKTKSGQ
GTIYGIAKGAGMIEPNMATMLCYILSDVSLPEGTDLYSILKSSVDQSFNCLTIDSDTSTSDTVALLCNGLSGESSVQDFS
KALTEICIDLTKLIATDGEGATKLIELTISGAKSEAQARKIGKSILNSPLVKTAIYGGDPNWGRLIMAVGKVFDEPIPFE
GLQIYFGTLPVKEANPETLKKLSEYLKNNTEISLNVVLNVGTISMKFWGCDFTEKYIEENAYYTT

Specific function: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis:the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate

COG id: COG1364

COG function: function code E; N-acetylglutamate synthase (N-acetylornithine aminotransferase)

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgJ family

Homologues:

Organism=Saccharomyces cerevisiae, GI6323707, Length=418, Percent_Identity=34.9282296650718, Blast_Score=197, Evalue=3e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGJ_LEPIC (P62062)

Other databases:

- EMBL:   AE016823
- RefSeq:   YP_003178.1
- ProteinModelPortal:   P62062
- SMR:   P62062
- GeneID:   2772095
- GenomeReviews:   AE016823_GR
- KEGG:   lic:LIC13271
- NMPDR:   fig|267671.1.peg.3178
- HOGENOM:   HBG284202
- OMA:   AMAIGKC
- ProtClustDB:   PRK05388
- BioCyc:   LINT-130-01:LINT-130-01-003178-MONOMER
- BioCyc:   LINT267671:LIC_13271-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01106
- InterPro:   IPR002813
- InterPro:   IPR016117
- PANTHER:   PTHR23100
- TIGRFAMs:   TIGR00120

Pfam domain/function: PF01960 ArgJ; SSF56266 Pept_S58_DmpA/Arg_biosyn_ArgJ

EC number: =2.3.1.35; =2.3.1.1

Molecular weight: Translated: 41503; Mature: 41503

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHMPKGFLSFGINIGIKDDTKDFGVIYSEIPCKATAVFTKNNFPGAPVIVGKEHVRSGVL
CCCCCCCHHCCEEEECCCCCCCCCEEEECCCCCEEEEEECCCCCCCCEEECHHHHHHCCE
QAIVINSKNSNVATGEKGIQNSREICKIIGESLDIKETLVLPSSTGVIGVPLKMEIILPA
EEEEEECCCCCCCCCCHHCCCHHHHHHHHCCCCCCCEEEEECCCCCEEECCEEEEEECHH
CKKAKSLLKPGNLEEVAEAIMTTDTRKKISSRNIKTKSGQGTIYGIAKGAGMIEPNMATM
HHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHCCCEECCCCEEEEEEECCCCCCCCCHHHH
LCYILSDVSLPEGTDLYSILKSSVDQSFNCLTIDSDTSTSDTVALLCNGLSGESSVQDFS
HHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEEEECCCCCHHHHHHH
KALTEICIDLTKLIATDGEGATKLIELTISGAKSEAQARKIGKSILNSPLVKTAIYGGDP
HHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCHHEEEECCCC
NWGRLIMAVGKVFDEPIPFEGLQIYFGTLPVKEANPETLKKLSEYLKNNTEISLNVVLNV
CHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEEEEEE
GTISMKFWGCDFTEKYIEENAYYTT
CEEEEEEECCCHHHHHHHCCCCCCC
>Mature Secondary Structure
MHMPKGFLSFGINIGIKDDTKDFGVIYSEIPCKATAVFTKNNFPGAPVIVGKEHVRSGVL
CCCCCCCHHCCEEEECCCCCCCCCEEEECCCCCEEEEEECCCCCCCCEEECHHHHHHCCE
QAIVINSKNSNVATGEKGIQNSREICKIIGESLDIKETLVLPSSTGVIGVPLKMEIILPA
EEEEEECCCCCCCCCCHHCCCHHHHHHHHCCCCCCCEEEEECCCCCEEECCEEEEEECHH
CKKAKSLLKPGNLEEVAEAIMTTDTRKKISSRNIKTKSGQGTIYGIAKGAGMIEPNMATM
HHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHCCCEECCCCEEEEEEECCCCCCCCCHHHH
LCYILSDVSLPEGTDLYSILKSSVDQSFNCLTIDSDTSTSDTVALLCNGLSGESSVQDFS
HHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEEEECCCCCHHHHHHH
KALTEICIDLTKLIATDGEGATKLIELTISGAKSEAQARKIGKSILNSPLVKTAIYGGDP
HHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCHHEEEECCCC
NWGRLIMAVGKVFDEPIPFEGLQIYFGTLPVKEANPETLKKLSEYLKNNTEISLNVVLNV
CHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEEEEEE
GTISMKFWGCDFTEKYIEENAYYTT
CEEEEEEECCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA