Click here to switch to the map view.

The map label for this gene is mltA

Identifier: 45659006

GI number: 45659006

Start: 3896135

End: 3897235

Strand: Reverse

Name: mltA

Synonym: LIC13184

Alternate gene names: 45659006

Gene position: 3897235-3896135 (Counterclockwise)

Preceding gene: 45659007

Following gene: 45659005

Centisome position: 91.12

GC content: 32.79

Gene sequence:

>1101_bases
ATGCGTTTGTTATCTATTTTTATTTGTTTTATTATACTCAACGTATATTCGTTATATTCGCAAGAGTTAGAAAAATCTGG
ATTTATTGTTCATCAAAAGTTCGATTCAATTTTACAATTGGAGGATTTTGATTCTTTGGATCGTGCTTTAAAAGAATCGG
AATCGTATTACCAAAAACTTCCTTCTAATTGGAAAACTCAAGTTCGAAAAACTTCGTATCATAAAAACCAAATGTTGAAT
TCTTTGAAGATTTTAAAAAAAATTCTTCGAGAAAAAAATCCAGAGTCTAGAAAAATCCAATTTCAAAATTCGTTTTTACT
TTTAGAAACAAAGGATGAAGCTCTTGGAAGAATTACTGCATATTATGAAGTTATAATAGAAGGGAGGTTTTATCCAGAAG
GAGATTTTATTTATCCAGTTTTGGAAACTCCATCTGATTTAATTGTAAAAAAAGACGGAAATAAAAAATCCGTTGGCAAA
ATTATAAATGAGGTTTTTGTTCCGTATGAAACTAGAGAGGAGTTGTCTCATACTTCCGTTTGGAAAAAACGATCAAAGGC
GATCGTATATGTCAAAATTGTAGATTTACATCTCGCACAATTAGAAGGTTCGGCTTTTGTAAAAGTTCCGGATCATATTC
CATTTCGCATAACGTATTCAGAGGATAATGGAAAAGAATATCAGAGTCCTGCGGAATCTCTAAAGGGAATTTGCAGTAGT
TTGATTCCTTCCGATTTAAAAAGTTGTATTCTTAAATATCCGAAAGAGGTCGAAATGGCTATCCTCAAAAATCCAAGATA
TATTTTTTTTAAACTAGAATCTTCTGCACCTCGAGGAAGTGGGGGAATTGAGCTGATTCCGAAACGGTCTGTTGCAATGG
ATCCAGGGATTCCTTTGGGGATTCCAGTTTTGATTTCTTTTGAATCTTCTGTTTTAACTGAAAAAAATAGAATTGTATTT
GTCCATGATAGAGGATCTCAAATTACGGGGCACGGTCGTTTGGATTATTTTTTGGGAACTGGTGAAACGGCAGAATATCA
AGCCGGGAAGATTAATACCCAAGGAAAAATTTTTTTAATTCTGCCTAAAATAAAGAATTAG

Upstream 100 bases:

>100_bases
AAATTATTACTGGGCTTACTTTCTAATTGAATGTTATAATTTAAAAAAAGATCGTTTGGGCCGCTACTGGATTTTAAATT
AAATATCGATAATCTATAAA

Downstream 100 bases:

>100_bases
ACTTTTGTAAATTAAGAATTTTTGAAATATTCTTCAATAGATTAACGTGGTCTAAAATGAGAAATTGGAGCGAACCGGGT
TCTCGGCTTTGGCTAATAAC

Product: putative membrane-bound lytic murein transglycosylase A transmembrane protein

Products: Muramic Acid Residue [C]

Alternate protein names: MltA Domain Protein; Membrane-Bound Lytic Murein Transglycosylase; Membrane-Bound Lytic Murein Transglycosylase A; MltA/3D Domain Protein; Transglycosylase; Membrane-Bound Lytic Transglycosylase A; MltA N-Terminal Domain Family; Membrane-Bound Transglycolase; MltA3D; Lytic Murein Transglycosylase A Protein; MltA Family Protein; Peptidoglycan N-Acetylmuramoylhydrolase; Murein Degrading Transglycosylase Protein; Lytic Murein Transglycosylase; Membrane-Bound Lytic Murein Transglycosylase Family Protein; Murein Transglycosylase A; Membrane-Bound Lytic Murein Transglycolase A; Outer Membrane-Bound Lytic Murein Transglycolase A; Mlta Domain Protein; MltA/3D Domain-Containing Protein; Outer Membrane-Bound Lytic Murein Transglycosylase; Transglycosylase MltA; Lipoprotein

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MRLLSIFICFIILNVYSLYSQELEKSGFIVHQKFDSILQLEDFDSLDRALKESESYYQKLPSNWKTQVRKTSYHKNQMLN
SLKILKKILREKNPESRKIQFQNSFLLLETKDEALGRITAYYEVIIEGRFYPEGDFIYPVLETPSDLIVKKDGNKKSVGK
IINEVFVPYETREELSHTSVWKKRSKAIVYVKIVDLHLAQLEGSAFVKVPDHIPFRITYSEDNGKEYQSPAESLKGICSS
LIPSDLKSCILKYPKEVEMAILKNPRYIFFKLESSAPRGSGGIELIPKRSVAMDPGIPLGIPVLISFESSVLTEKNRIVF
VHDRGSQITGHGRLDYFLGTGETAEYQAGKINTQGKIFLILPKIKN

Sequences:

>Translated_366_residues
MRLLSIFICFIILNVYSLYSQELEKSGFIVHQKFDSILQLEDFDSLDRALKESESYYQKLPSNWKTQVRKTSYHKNQMLN
SLKILKKILREKNPESRKIQFQNSFLLLETKDEALGRITAYYEVIIEGRFYPEGDFIYPVLETPSDLIVKKDGNKKSVGK
IINEVFVPYETREELSHTSVWKKRSKAIVYVKIVDLHLAQLEGSAFVKVPDHIPFRITYSEDNGKEYQSPAESLKGICSS
LIPSDLKSCILKYPKEVEMAILKNPRYIFFKLESSAPRGSGGIELIPKRSVAMDPGIPLGIPVLISFESSVLTEKNRIVF
VHDRGSQITGHGRLDYFLGTGETAEYQAGKINTQGKIFLILPKIKN
>Mature_366_residues
MRLLSIFICFIILNVYSLYSQELEKSGFIVHQKFDSILQLEDFDSLDRALKESESYYQKLPSNWKTQVRKTSYHKNQMLN
SLKILKKILREKNPESRKIQFQNSFLLLETKDEALGRITAYYEVIIEGRFYPEGDFIYPVLETPSDLIVKKDGNKKSVGK
IINEVFVPYETREELSHTSVWKKRSKAIVYVKIVDLHLAQLEGSAFVKVPDHIPFRITYSEDNGKEYQSPAESLKGICSS
LIPSDLKSCILKYPKEVEMAILKNPRYIFFKLESSAPRGSGGIELIPKRSVAMDPGIPLGIPVLISFESSVLTEKNRIVF
VHDRGSQITGHGRLDYFLGTGETAEYQAGKINTQGKIFLILPKIKN

Specific function: Murein-Degrading Enzyme. May Play A Role In Recycling Of Muropeptides During Cell Elongation And/Or Cell Division. Optimal Activity Is Between pH 4.0 And 4.5; Loses Its Activity Rapidly At Temperatures Above 30 Degrees Celsius. Degrades Murein Glycan Stra

COG id: COG2821

COG function: function code M; Membrane-bound lytic murein transglycosylase

Gene ontology:

Cell location: Attached To The Outer Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.2.1.- [C]

Molecular weight: Translated: 41871; Mature: 41871

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLSIFICFIILNVYSLYSQELEKSGFIVHQKFDSILQLEDFDSLDRALKESESYYQKL
CHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHCCHHHHHHHHHHHHHHHHHC
PSNWKTQVRKTSYHKNQMLNSLKILKKILREKNPESRKIQFQNSFLLLETKDEALGRITA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCEEEEEECCHHHHHHHE
YYEVIIEGRFYPEGDFIYPVLETPSDLIVKKDGNKKSVGKIINEVFVPYETREELSHTSV
EEEEEEECCCCCCCCEEEEEECCCCCEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHH
WKKRSKAIVYVKIVDLHLAQLEGSAFVKVPDHIPFRITYSEDNGKEYQSPAESLKGICSS
HHHCCCEEEEEEEEEEEEEHCCCCEEEECCCCCCEEEEEECCCCCHHCCHHHHHHHHHHH
LIPSDLKSCILKYPKEVEMAILKNPRYIFFKLESSAPRGSGGIELIPKRSVAMDPGIPLG
HCHHHHHHHHHHCCCHHHHHEECCCCEEEEEEECCCCCCCCCEEEEECCCCCCCCCCCCC
IPVLISFESSVLTEKNRIVFVHDRGSQITGHGRLDYFLGTGETAEYQAGKINTQGKIFLI
CEEEEEECHHHCCCCCCEEEEECCCCEEECCCCEEEEEECCCCCCCCCCEECCCCEEEEE
LPKIKN
ECCCCC
>Mature Secondary Structure
MRLLSIFICFIILNVYSLYSQELEKSGFIVHQKFDSILQLEDFDSLDRALKESESYYQKL
CHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHCCHHHHHHHHHHHHHHHHHC
PSNWKTQVRKTSYHKNQMLNSLKILKKILREKNPESRKIQFQNSFLLLETKDEALGRITA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCEEEEEECCHHHHHHHE
YYEVIIEGRFYPEGDFIYPVLETPSDLIVKKDGNKKSVGKIINEVFVPYETREELSHTSV
EEEEEEECCCCCCCCEEEEEECCCCCEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHH
WKKRSKAIVYVKIVDLHLAQLEGSAFVKVPDHIPFRITYSEDNGKEYQSPAESLKGICSS
HHHCCCEEEEEEEEEEEEEHCCCCEEEECCCCCCEEEEEECCCCCHHCCHHHHHHHHHHH
LIPSDLKSCILKYPKEVEMAILKNPRYIFFKLESSAPRGSGGIELIPKRSVAMDPGIPLG
HCHHHHHHHHHHCCCHHHHHEECCCCEEEEEEECCCCCCCCCEEEEECCCCCCCCCCCCC
IPVLISFESSVLTEKNRIVFVHDRGSQITGHGRLDYFLGTGETAEYQAGKINTQGKIFLI
CEEEEEECHHHCCCCCCEEEEECCCCEEECCCCEEEEEECCCCCCCCCCEECCCCEEEEE
LPKIKN
ECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic [C]

General reaction: Cleavage Bond [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA