| Definition | Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_005823 |
| Length | 4,277,185 |
Click here to switch to the map view.
The map label for this gene is kinE [H]
Identifier: 45658934
GI number: 45658934
Start: 3805797
End: 3808106
Strand: Reverse
Name: kinE [H]
Synonym: LIC13111
Alternate gene names: 45658934
Gene position: 3808106-3805797 (Counterclockwise)
Preceding gene: 45658935
Following gene: 45658933
Centisome position: 89.03
GC content: 35.76
Gene sequence:
>2310_bases ATGCCAGATTCATTACTTTCCGTGTTTTATTCTTTTTTCCATCCTACTCAGGAAGGAATTCTTGCTTTAGATACAGAGAC GGAAACTATTCTTTATTTAAATCCAGCTCTTGAAAACATCTTAGGTTATTCCTCGGAAGAGCTCCAGGGAAAATCACTCG ATTTCATTTTATCTAGTTCGACACATCCAAAAGAAACTCTAACAATCAAACACAACGAACCCTTAAGAGTTTATTGGCAA CTCAAACATAAAAGTGGAGAAGACAAACTTGTAAATTTTACGGTAAACAGTACTCACTTTGAAGGAAGAGGATTGTTGTT ATTTTATTTCACCGATCAGTCTGAAATTCAGCAGACAGAACTCAGACTTTATTATATGCAAAGTATCTTAAGAACCTTAA GGCTTTTAAGACAAAACTTAAGATATTTGACTTCTGAGAGTTCTATCTTTCAAAAACTCTGCGATACTCTTAAGGAAAAT CCGCATTACTTTTTAGTTTGGGCTTTTTTTTTCAAGGAAGGAGAGTTACAAATTCTGGGACAAAAGGGGATGAATCCAGA ATTAAAACATAAAATTCATTCATTCATTTCTTCTAATGTTCCATTTCCGATGAGAAATTTGATAGATACAAAGGATAACT TTGTCATACATGAATTCGGTAATGGGAAGTATCCGGAATGGGAATCTATTTTTACGGATCATAAATTCCGAAGAAGTCTT TCTCTTGGAATCCGAGAAAAAGAAAACCTTTTAGGAGGAGTTGAAATTCTATCTTTAGAGGAAATGGCTTTTGATTCCGG TGAAAATTTTCTATATGAGGAAATTCTTTCGGACATACATAGCTCGTTACAAAATGCTAAGACGGAACGAACCAGGATTG AAAATTCCAAAAAATTACAGTTTCAAGGAGCACTTCTTAATTCTATAGAAGTCCCTCTTATCTCCACTGATGACGAGGGT TATATTACGTACGGAAACAGAAGTCTTGAAAGAATATTAGGAGTTTATAAAGAAGATTTCATTGATCTTCCAATTGGCGA ATTTTTAAATTTGCCTCCAGCCGTTTTAGAGAGACTTTCTAAGGAAGAATTCAGAACCGAAATCAAAATGAAAATTTTTC CAGATATGGAAGTGCCAATGCTTCTTGCCTCTTCGAGAATAAGGGATGAATATGGAAATCCTATTGGAACTATTTTGTTA CTTCTAGATATTACGGAACAAAAGAAGAATGAGGAATTGATCCGTTCTTCCGAAATCAAACTGAGAAACTTATTTTCTGC GATGAACAATGGAATTGTAATCCTCACTTCAGAAGGAATCGTTTTAGAAGTGGCTCCGATTCTCAAGTTCCTTTTATTCC AAATATTGAATGTAGTTATCGGTGAGAATTTTTTCTCGCTTTTTGTTCAGAATGTAGCGGAAGAACTTAAAAACGGAGTC AAAAACTGTCTCGATTCCAGAAGAGCTGTATTTTTAGACCTTTTAATTCCGTTTATTAGGGAGCAGGAAAATTTCTTTTC GATTAAAATTCTTCCGTTAAAAAAATATAGGGAAAACGGAGGTGAGGCAGTTATGTTGATCTTCTCGGATGTCACACAAA CCAAACTTCTGGACAAACAACTTTATGAAACCGCAAGATTCGCTTCTATAGGAGAACTCGCCGCAGGGATTGCGCACGAA GTAAATAATCCTCTTCAGGCGAGTTTACTTTATCTAGAAGAGTTAATAGAAACCGAAGAATCTGATCCTGCAGAAAGGTT AAAGATTTATAAAAGAATTGAAGCTGCAAGTGTTCGAATCCGAGATCTTATTAAGTCTTTACTGGATTTAGGAAGAACCG TAGCAAGGGAAAAAGAACTTGTATCTCCTTACTACATTCTTCTCAGAGCTTGCGAGTTGATTGAAGTTTCCTGTAAAAAA AATGGGATCGAATTAAAACGAATTGCAGATCCGGATCTTCCTAAAATTCGAGCTGCTTGGCAAGAAATCGAACAGGTTTT AATCAATTGTTTGGTAAACGCGATTAACGCGATTGCCGAAATGGAAACAAAACCTTTTTTACCTAATATTTCGATCACGG TTCAGAAAGAATTTCATTTGAATCGAGACTCGATTCTTTTTACAATTTCGGATAACGGCCCAGGAATGACTAAAGAAGTT TTAGAAAAAGCGTTTCTTCCTCTTTATACTACTCGGAGAGGAAAACAAGGAACCGGTTTGGGGCTTTCCATTTCCCAAAG AATCATTTCGGAACACAATGGAACCATCTCTTTTTGGAGTCTTCCATTGGAAATGGAACTAGGGTTTTGA
Upstream 100 bases:
>100_bases TTATCAAAGAGACGTTTGATTTGGTATGTTTTCCGGAATTAGTTCTTGCAAAGAATCGAAAGTAAGTCGAGACTCACTTC AGGTTATACTGGAAATCAGG
Downstream 100 bases:
>100_bases TTCGCCTTCCTATATAAGGACGTTTTTTTGGTAAAATAGAGTTTAGTGCAAAAGTTTATGGAATCAAAGTTTACATCGGT ACTCGTAATCGACGATGAAT
Product: histidine kinase sensor protein
Products: NA
Alternate protein names: Sensor histidine kinase E [H]
Number of amino acids: Translated: 769; Mature: 768
Protein sequence:
>769_residues MPDSLLSVFYSFFHPTQEGILALDTETETILYLNPALENILGYSSEELQGKSLDFILSSSTHPKETLTIKHNEPLRVYWQ LKHKSGEDKLVNFTVNSTHFEGRGLLLFYFTDQSEIQQTELRLYYMQSILRTLRLLRQNLRYLTSESSIFQKLCDTLKEN PHYFLVWAFFFKEGELQILGQKGMNPELKHKIHSFISSNVPFPMRNLIDTKDNFVIHEFGNGKYPEWESIFTDHKFRRSL SLGIREKENLLGGVEILSLEEMAFDSGENFLYEEILSDIHSSLQNAKTERTRIENSKKLQFQGALLNSIEVPLISTDDEG YITYGNRSLERILGVYKEDFIDLPIGEFLNLPPAVLERLSKEEFRTEIKMKIFPDMEVPMLLASSRIRDEYGNPIGTILL LLDITEQKKNEELIRSSEIKLRNLFSAMNNGIVILTSEGIVLEVAPILKFLLFQILNVVIGENFFSLFVQNVAEELKNGV KNCLDSRRAVFLDLLIPFIREQENFFSIKILPLKKYRENGGEAVMLIFSDVTQTKLLDKQLYETARFASIGELAAGIAHE VNNPLQASLLYLEELIETEESDPAERLKIYKRIEAASVRIRDLIKSLLDLGRTVAREKELVSPYYILLRACELIEVSCKK NGIELKRIADPDLPKIRAAWQEIEQVLINCLVNAINAIAEMETKPFLPNISITVQKEFHLNRDSILFTISDNGPGMTKEV LEKAFLPLYTTRRGKQGTGLGLSISQRIISEHNGTISFWSLPLEMELGF
Sequences:
>Translated_769_residues MPDSLLSVFYSFFHPTQEGILALDTETETILYLNPALENILGYSSEELQGKSLDFILSSSTHPKETLTIKHNEPLRVYWQ LKHKSGEDKLVNFTVNSTHFEGRGLLLFYFTDQSEIQQTELRLYYMQSILRTLRLLRQNLRYLTSESSIFQKLCDTLKEN PHYFLVWAFFFKEGELQILGQKGMNPELKHKIHSFISSNVPFPMRNLIDTKDNFVIHEFGNGKYPEWESIFTDHKFRRSL SLGIREKENLLGGVEILSLEEMAFDSGENFLYEEILSDIHSSLQNAKTERTRIENSKKLQFQGALLNSIEVPLISTDDEG YITYGNRSLERILGVYKEDFIDLPIGEFLNLPPAVLERLSKEEFRTEIKMKIFPDMEVPMLLASSRIRDEYGNPIGTILL LLDITEQKKNEELIRSSEIKLRNLFSAMNNGIVILTSEGIVLEVAPILKFLLFQILNVVIGENFFSLFVQNVAEELKNGV KNCLDSRRAVFLDLLIPFIREQENFFSIKILPLKKYRENGGEAVMLIFSDVTQTKLLDKQLYETARFASIGELAAGIAHE VNNPLQASLLYLEELIETEESDPAERLKIYKRIEAASVRIRDLIKSLLDLGRTVAREKELVSPYYILLRACELIEVSCKK NGIELKRIADPDLPKIRAAWQEIEQVLINCLVNAINAIAEMETKPFLPNISITVQKEFHLNRDSILFTISDNGPGMTKEV LEKAFLPLYTTRRGKQGTGLGLSISQRIISEHNGTISFWSLPLEMELGF >Mature_768_residues PDSLLSVFYSFFHPTQEGILALDTETETILYLNPALENILGYSSEELQGKSLDFILSSSTHPKETLTIKHNEPLRVYWQL KHKSGEDKLVNFTVNSTHFEGRGLLLFYFTDQSEIQQTELRLYYMQSILRTLRLLRQNLRYLTSESSIFQKLCDTLKENP HYFLVWAFFFKEGELQILGQKGMNPELKHKIHSFISSNVPFPMRNLIDTKDNFVIHEFGNGKYPEWESIFTDHKFRRSLS LGIREKENLLGGVEILSLEEMAFDSGENFLYEEILSDIHSSLQNAKTERTRIENSKKLQFQGALLNSIEVPLISTDDEGY ITYGNRSLERILGVYKEDFIDLPIGEFLNLPPAVLERLSKEEFRTEIKMKIFPDMEVPMLLASSRIRDEYGNPIGTILLL LDITEQKKNEELIRSSEIKLRNLFSAMNNGIVILTSEGIVLEVAPILKFLLFQILNVVIGENFFSLFVQNVAEELKNGVK NCLDSRRAVFLDLLIPFIREQENFFSIKILPLKKYRENGGEAVMLIFSDVTQTKLLDKQLYETARFASIGELAAGIAHEV NNPLQASLLYLEELIETEESDPAERLKIYKRIEAASVRIRDLIKSLLDLGRTVAREKELVSPYYILLRACELIEVSCKKN GIELKRIADPDLPKIRAAWQEIEQVLINCLVNAINAIAEMETKPFLPNISITVQKEFHLNRDSILFTISDNGPGMTKEVL EKAFLPLYTTRRGKQGTGLGLSISQRIISEHNGTISFWSLPLEMELGF
Specific function: Phosphorylates the sporulation-regulatory protein spo0A under biofilm growth conditions. Also able to weakly phosphorylate spo0F [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Integral Membrane Protein. Inner Membrane [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 4 PAS (PER-ARNT-SIM) domains [H]
Homologues:
Organism=Escherichia coli, GI1788549, Length=243, Percent_Identity=32.5102880658436, Blast_Score=109, Evalue=8e-25, Organism=Escherichia coli, GI1790300, Length=249, Percent_Identity=29.3172690763052, Blast_Score=94, Evalue=4e-20, Organism=Escherichia coli, GI1790436, Length=236, Percent_Identity=27.5423728813559, Blast_Score=92, Evalue=1e-19,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003594 - InterPro: IPR000014 - InterPro: IPR013767 - InterPro: IPR004358 - InterPro: IPR003661 - InterPro: IPR005467 - InterPro: IPR009082 [H]
Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]
EC number: =2.7.13.3 [H]
Molecular weight: Translated: 88238; Mature: 88107
Theoretical pI: Translated: 5.12; Mature: 5.12
Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 1.7 %Met (Translated Protein) 2.3 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 2.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MPDSLLSVFYSFFHPTQEGILALDTETETILYLNPALENILGYSSEELQGKSLDFILSSS CCHHHHHHHHHHHCCCCCCEEEEECCCCEEEEECHHHHHHHCCCCHHCCCCCEEEEECCC THPKETLTIKHNEPLRVYWQLKHKSGEDKLVNFTVNSTHFEGRGLLLFYFTDQSEIQQTE CCCCEEEEEECCCCEEEEEEEECCCCCCEEEEEEEECEEECCCEEEEEEECCCHHHHHHH LRLYYMQSILRTLRLLRQNLRYLTSESSIFQKLCDTLKENPHYFLVWAFFFKEGELQILG HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCEEEEC QKGMNPELKHKIHSFISSNVPFPMRNLIDTKDNFVIHEFGNGKYPEWESIFTDHKFRRSL CCCCCHHHHHHHHHHHHCCCCCCHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHH SLGIREKENLLGGVEILSLEEMAFDSGENFLYEEILSDIHSSLQNAKTERTRIENSKKLQ HCCCCHHHHHHCCHHEEEHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE FQGALLNSIEVPLISTDDEGYITYGNRSLERILGVYKEDFIDLPIGEFLNLPPAVLERLS EECHHHCCCCCCEEECCCCCEEEECCHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHH KEEFRTEIKMKIFPDMEVPMLLASSRIRDEYGNPIGTILLLLDITEQKKNEELIRSSEIK HHHHHHHEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHEEEEECHHCCCHHHHHHHHHHH LRNLFSAMNNGIVILTSEGIVLEVAPILKFLLFQILNVVIGENFFSLFVQNVAEELKNGV HHHHHHHHCCCEEEEECCCCEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH KNCLDSRRAVFLDLLIPFIREQENFFSIKILPLKKYRENGGEAVMLIFSDVTQTKLLDKQ HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEHHHHHCCCCCEEEEEECCCHHHHHHHHH LYETARFASIGELAAGIAHEVNNPLQASLLYLEELIETEESDPAERLKIYKRIEAASVRI HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH RDLIKSLLDLGRTVAREKELVSPYYILLRACELIEVSCKKNGIELKRIADPDLPKIRAAW HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHH QEIEQVLINCLVNAINAIAEMETKPFLPNISITVQKEFHLNRDSILFTISDNGPGMTKEV HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCEEEEECCCCCCCHHHH LEKAFLPLYTTRRGKQGTGLGLSISQRIISEHNGTISFWSLPLEMELGF HHHHCCCHHHCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCEEEECCC >Mature Secondary Structure PDSLLSVFYSFFHPTQEGILALDTETETILYLNPALENILGYSSEELQGKSLDFILSSS CHHHHHHHHHHHCCCCCCEEEEECCCCEEEEECHHHHHHHCCCCHHCCCCCEEEEECCC THPKETLTIKHNEPLRVYWQLKHKSGEDKLVNFTVNSTHFEGRGLLLFYFTDQSEIQQTE CCCCEEEEEECCCCEEEEEEEECCCCCCEEEEEEEECEEECCCEEEEEEECCCHHHHHHH LRLYYMQSILRTLRLLRQNLRYLTSESSIFQKLCDTLKENPHYFLVWAFFFKEGELQILG HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCEEEEC QKGMNPELKHKIHSFISSNVPFPMRNLIDTKDNFVIHEFGNGKYPEWESIFTDHKFRRSL CCCCCHHHHHHHHHHHHCCCCCCHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHH SLGIREKENLLGGVEILSLEEMAFDSGENFLYEEILSDIHSSLQNAKTERTRIENSKKLQ HCCCCHHHHHHCCHHEEEHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE FQGALLNSIEVPLISTDDEGYITYGNRSLERILGVYKEDFIDLPIGEFLNLPPAVLERLS EECHHHCCCCCCEEECCCCCEEEECCHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHH KEEFRTEIKMKIFPDMEVPMLLASSRIRDEYGNPIGTILLLLDITEQKKNEELIRSSEIK HHHHHHHEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHEEEEECHHCCCHHHHHHHHHHH LRNLFSAMNNGIVILTSEGIVLEVAPILKFLLFQILNVVIGENFFSLFVQNVAEELKNGV HHHHHHHHCCCEEEEECCCCEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH KNCLDSRRAVFLDLLIPFIREQENFFSIKILPLKKYRENGGEAVMLIFSDVTQTKLLDKQ HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEHHHHHCCCCCEEEEEECCCHHHHHHHHH LYETARFASIGELAAGIAHEVNNPLQASLLYLEELIETEESDPAERLKIYKRIEAASVRI HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH RDLIKSLLDLGRTVAREKELVSPYYILLRACELIEVSCKKNGIELKRIADPDLPKIRAAW HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHH QEIEQVLINCLVNAINAIAEMETKPFLPNISITVQKEFHLNRDSILFTISDNGPGMTKEV HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCEEEEECCCCCCCHHHH LEKAFLPLYTTRRGKQGTGLGLSISQRIISEHNGTISFWSLPLEMELGF HHHHCCCHHHCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCEEEECCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 9384377 [H]