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The map label for this gene is atoS [H]

Identifier: 45658933

GI number: 45658933

Start: 3804228

End: 3805751

Strand: Reverse

Name: atoS [H]

Synonym: LIC13110

Alternate gene names: 45658933

Gene position: 3805751-3804228 (Counterclockwise)

Preceding gene: 45658934

Following gene: 45658932

Centisome position: 88.98

GC content: 36.09

Gene sequence:

>1524_bases
GTGCAAAAGTTTATGGAATCAAAGTTTACATCGGTACTCGTAATCGACGATGAATTCGAAATTCGTATCGTTTTGGAAAG
AGTTATTTCCAAAGAAGGTTATCAAGTATTATCCGCAAAGGATTCGGATTCTGCTCTCGAAATTATTCGAAACCAAAAAG
TGGATGTGGTTATTTCGGATATCGTAATGAACGGTAAAAGTGGAATCGAAGTTGTAAAAGAAATCCGTAAAATCAATGAA
AATATTCCAGTCATTTTAATGACTGGAAATCCCGATCTCAATTCTGCGGAAGAAGCTGTCCGCAATCGGGCATTCGATTA
CATATCTAAACCGATCCGTCGTAGAAACATTTTGGAGATATTAGAAAGAGCTAAAATAGAAAAAGAAACCAGGGATAAAC
GTGCAGAAAATCTGATTAAATCGGAAACGGAAAATACTAAACTCGCACAAAGAGCTAAGGACTTATATTTACAAAATTAT
AATATTCTTAACGCAACTAGTGATTGTGTAATTACTTTGGATCGAGAATTGAAATTTTCGGGTTTAAACCGAGCCGCATT
AGATGCATTTGGATACGTCGAAGAAGAAATTGTAGGAAAACATTTTGAAGTTCTGATACCAGTTGGAAAAGAAAAACTTT
ATATGGAACGGCTAAATCGGCTCTTAAAAAGAAAAAATAAAAAGCAAATTTCAAGAATCAGCCGAGCCGATCTAAAAAGT
AAAAATGGGGAAGTAAGAGCTTATGAAATTTCGATATGTTATTATGACATAGAAGGTCAAACTTATTATACTGGAATTGC
GAGAGATATAACGAGTAAACTTTTGATTTCTGAAAAACTCATAGATGCGGAACGTAGGGCGTTTCTTTCGATTCTTGCTT
CGAGTATAGGACACGAGATTAACAATTCTTTGACTGCGATTCAAGGTCATATAGAGATTGCAAAACTTCCAGATGCAACG
GATCCGATTCGTCAAAAGGCGATTCAGATCACTTGGAGTCAATTGGTCAAATTGAAGACTCTTACAAACAACCTTTTACA
GTTAGGGAAACCAGGTGAGAATTTCAAAAGGGCTTCGGAGCCGATTGATCTAAACGAATGTGTGGAAAGTGTAATCGACG
TTTTTCAGAAAACTTCCAGACTTAAAAACTGTAAGATCCATTTTAAACCGGAACCGATACCAGTGATTGTAGAATCGAAT
CAGGATCAACTTTCTCTTTTACTTTCCAATATCGTATTAAATTCCGCGGACGCAACTGGAAATCAGGGGAATATTCAAAT
TTCTGTATATATTAAAAATCATCATCCTGTCGTGTCTGTTTTGGACGATGGAGTTGGAATGGACGAAGAAGTGATTCAAA
AAATTTATCAACCGTATTTTACTACAAAAGGAATTGGGAAGGGAACTGGACTCGGAATGTTTGTAGCCAAGGAAATTGCG
GACCAACACAAAATTAAAATCGAAATTGAATCGGAGCCGAACTTCGGAACTGAATTCCGTTTAATTTTTCCGAATAAGGT
ATAA

Upstream 100 bases:

>100_bases
CAATGGAACCATCTCTTTTTGGAGTCTTCCATTGGAAATGGAACTAGGGTTTTGATTCGCCTTCCTATATAAGGACGTTT
TTTTGGTAAAATAGAGTTTA

Downstream 100 bases:

>100_bases
TACTATGAACATTTCAATTCCTCTCACGGATCCAGAGCTGAAGTTTTTGGAATTCTCTGGAAAACTTCCTCAAGAAATTA
CTCCGATCGTTTCCGAAGCC

Product: histidine kinase response regulator hybrid protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 507; Mature: 507

Protein sequence:

>507_residues
MQKFMESKFTSVLVIDDEFEIRIVLERVISKEGYQVLSAKDSDSALEIIRNQKVDVVISDIVMNGKSGIEVVKEIRKINE
NIPVILMTGNPDLNSAEEAVRNRAFDYISKPIRRRNILEILERAKIEKETRDKRAENLIKSETENTKLAQRAKDLYLQNY
NILNATSDCVITLDRELKFSGLNRAALDAFGYVEEEIVGKHFEVLIPVGKEKLYMERLNRLLKRKNKKQISRISRADLKS
KNGEVRAYEISICYYDIEGQTYYTGIARDITSKLLISEKLIDAERRAFLSILASSIGHEINNSLTAIQGHIEIAKLPDAT
DPIRQKAIQITWSQLVKLKTLTNNLLQLGKPGENFKRASEPIDLNECVESVIDVFQKTSRLKNCKIHFKPEPIPVIVESN
QDQLSLLLSNIVLNSADATGNQGNIQISVYIKNHHPVVSVLDDGVGMDEEVIQKIYQPYFTTKGIGKGTGLGMFVAKEIA
DQHKIKIEIESEPNFGTEFRLIFPNKV

Sequences:

>Translated_507_residues
MQKFMESKFTSVLVIDDEFEIRIVLERVISKEGYQVLSAKDSDSALEIIRNQKVDVVISDIVMNGKSGIEVVKEIRKINE
NIPVILMTGNPDLNSAEEAVRNRAFDYISKPIRRRNILEILERAKIEKETRDKRAENLIKSETENTKLAQRAKDLYLQNY
NILNATSDCVITLDRELKFSGLNRAALDAFGYVEEEIVGKHFEVLIPVGKEKLYMERLNRLLKRKNKKQISRISRADLKS
KNGEVRAYEISICYYDIEGQTYYTGIARDITSKLLISEKLIDAERRAFLSILASSIGHEINNSLTAIQGHIEIAKLPDAT
DPIRQKAIQITWSQLVKLKTLTNNLLQLGKPGENFKRASEPIDLNECVESVIDVFQKTSRLKNCKIHFKPEPIPVIVESN
QDQLSLLLSNIVLNSADATGNQGNIQISVYIKNHHPVVSVLDDGVGMDEEVIQKIYQPYFTTKGIGKGTGLGMFVAKEIA
DQHKIKIEIESEPNFGTEFRLIFPNKV
>Mature_507_residues
MQKFMESKFTSVLVIDDEFEIRIVLERVISKEGYQVLSAKDSDSALEIIRNQKVDVVISDIVMNGKSGIEVVKEIRKINE
NIPVILMTGNPDLNSAEEAVRNRAFDYISKPIRRRNILEILERAKIEKETRDKRAENLIKSETENTKLAQRAKDLYLQNY
NILNATSDCVITLDRELKFSGLNRAALDAFGYVEEEIVGKHFEVLIPVGKEKLYMERLNRLLKRKNKKQISRISRADLKS
KNGEVRAYEISICYYDIEGQTYYTGIARDITSKLLISEKLIDAERRAFLSILASSIGHEINNSLTAIQGHIEIAKLPDAT
DPIRQKAIQITWSQLVKLKTLTNNLLQLGKPGENFKRASEPIDLNECVESVIDVFQKTSRLKNCKIHFKPEPIPVIVESN
QDQLSLLLSNIVLNSADATGNQGNIQISVYIKNHHPVVSVLDDGVGMDEEVIQKIYQPYFTTKGIGKGTGLGMFVAKEIA
DQHKIKIEIESEPNFGTEFRLIFPNKV

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=368, Percent_Identity=26.6304347826087, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1790436, Length=238, Percent_Identity=28.1512605042017, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1790299, Length=113, Percent_Identity=36.283185840708, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790437, Length=131, Percent_Identity=32.824427480916, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI48994928, Length=395, Percent_Identity=24.8101265822785, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788550, Length=124, Percent_Identity=34.6774193548387, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786600, Length=252, Percent_Identity=25.7936507936508, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788905, Length=120, Percent_Identity=28.3333333333333, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790346, Length=233, Percent_Identity=23.6051502145923, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1788713, Length=224, Percent_Identity=23.6607142857143, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788393, Length=227, Percent_Identity=23.3480176211454, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1786912, Length=234, Percent_Identity=24.7863247863248, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 57504; Mature: 57504

Theoretical pI: Translated: 7.96; Mature: 7.96

Prosite motif: PS50112 PAS ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN ; PS00136 SUBTILASE_ASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKFMESKFTSVLVIDDEFEIRIVLERVISKEGYQVLSAKDSDSALEIIRNQKVDVVISD
CCHHHHCCCCEEEEECCCCHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHCCCCEEEEEE
IVMNGKSGIEVVKEIRKINENIPVILMTGNPDLNSAEEAVRNRAFDYISKPIRRRNILEI
HHHCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LERAKIEKETRDKRAENLIKSETENTKLAQRAKDLYLQNYNILNATSDCVITLDRELKFS
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEECCCCCEEEEEECCEECC
GLNRAALDAFGYVEEEIVGKHFEVLIPVGKEKLYMERLNRLLKRKNKKQISRISRADLKS
CCCHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
KNGEVRAYEISICYYDIEGQTYYTGIARDITSKLLISEKLIDAERRAFLSILASSIGHEI
CCCCEEEEEEEEEEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NNSLTAIQGHIEIAKLPDATDPIRQKAIQITWSQLVKLKTLTNNLLQLGKPGENFKRASE
CCCCEEEECCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCC
PIDLNECVESVIDVFQKTSRLKNCKIHFKPEPIPVIVESNQDQLSLLLSNIVLNSADATG
CCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEEECCCHHHHHHHHHHHHCCCCCCC
NQGNIQISVYIKNHHPVVSVLDDGVGMDEEVIQKIYQPYFTTKGIGKGTGLGMFVAKEIA
CCCCEEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHCHHCCCCCCCCCCHHHHHHHHHC
DQHKIKIEIESEPNFGTEFRLIFPNKV
CCCEEEEEEECCCCCCCEEEEECCCCC
>Mature Secondary Structure
MQKFMESKFTSVLVIDDEFEIRIVLERVISKEGYQVLSAKDSDSALEIIRNQKVDVVISD
CCHHHHCCCCEEEEECCCCHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHCCCCEEEEEE
IVMNGKSGIEVVKEIRKINENIPVILMTGNPDLNSAEEAVRNRAFDYISKPIRRRNILEI
HHHCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LERAKIEKETRDKRAENLIKSETENTKLAQRAKDLYLQNYNILNATSDCVITLDRELKFS
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEECCCCCEEEEEECCEECC
GLNRAALDAFGYVEEEIVGKHFEVLIPVGKEKLYMERLNRLLKRKNKKQISRISRADLKS
CCCHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
KNGEVRAYEISICYYDIEGQTYYTGIARDITSKLLISEKLIDAERRAFLSILASSIGHEI
CCCCEEEEEEEEEEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NNSLTAIQGHIEIAKLPDATDPIRQKAIQITWSQLVKLKTLTNNLLQLGKPGENFKRASE
CCCCEEEECCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCC
PIDLNECVESVIDVFQKTSRLKNCKIHFKPEPIPVIVESNQDQLSLLLSNIVLNSADATG
CCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEEECCCHHHHHHHHHHHHCCCCCCC
NQGNIQISVYIKNHHPVVSVLDDGVGMDEEVIQKIYQPYFTTKGIGKGTGLGMFVAKEIA
CCCCEEEEEEEECCCCEEEEECCCCCCCHHHHHHHHHCHHCCCCCCCCCCHHHHHHHHHC
DQHKIKIEIESEPNFGTEFRLIFPNKV
CCCEEEEEEECCCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]