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The map label for this gene is cya1 [H]

Identifier: 45658831

GI number: 45658831

Start: 3655614

End: 3656858

Strand: Direct

Name: cya1 [H]

Synonym: LIC13004

Alternate gene names: 45658831

Gene position: 3655614-3656858 (Clockwise)

Preceding gene: 45658829

Following gene: 45658833

Centisome position: 85.47

GC content: 38.31

Gene sequence:

>1245_bases
TTGAGAGCAACTTTAATTACTATTCCAAATACAAATGATATGCGAGCGTCGAAAGTAAAAATGAAAGACATTATCCATTG
GTTATCCACTCACGAATCCAGAGCCTTAGAGGCCAAAGAACTGATAGAAATTTTAAGTCGTAAAATGATGGAGGCCGGAA
TTCCGATCTGGAGATTTTTTACGAGTATCCCCACCATGCACCCAGAAGTGATGGTGAGATCGATCATTTGGACAAGAGGA
GAAGAAACTCAAATCGTATTCATTCCACACGATGGCTTACAACAACCGCAATATAAAGATAGTCCGATCTATCTCATCCG
GGAAAAACAAATCGATTTTATTCGTTGTAAATTGACCGGCCCAGAAGCAGATCTTTCTTACCCGATCTGTATCGACTTAC
ACGAAAAAGGTGGAACGGATTATTGTATCTTCGCTTCCGTTTTTGGAAATAATACACGAAGTGCCATTTCTTGGAGCACG
GACACGCCTGGCGGTTTTACGGATGAACAAATTGATTGTTTAAATTCGATTCGAAGTATTTTGTCTTTACGTTTAGATTT
AGAATCCAGAAAATTTTCAATCAATGAACTTTTAGAAGTTTATTTAGGTCCTAACGCTTCTAAAAGAGTCTTATCTGGAG
AATTTAGAAGAGGCACAGGAGAAACAATCTACGCGGCAATTCTTTGCGCAGATTTACGAGACTTCTCATTTTTAAGCGAA
AATAATCCTCCAAAAAGAATCGTGGAAATTTTAGACAATTACTTTGAACTAACCGCACAACCTATTCAAGAAGAAAAAGG
AGAAATTTTAAAATTTATAGGAGACGCGATTCTTGCAATTTTTCCTGCAGAAGTAGATTCGTATAAGGCATGTTTGGCGG
CACTCAATGCGGCTCAAAAGATTAAGAATTCCGTAATACGATGGAACGAAGAACATCCGGATTTACAAATTTATCTGGGT
ATGGCGCTGAACGTTGGAGACGTAGTTTATGGTAACGTAGGTGCAAAAGATAGACTTGATTTTACCGTAATCGGAAACGC
GGTCAATCAGGCTTTTCGAGTCGAGTCTTTGTGTAAAGATTTAGGAAAAAATATTCTTGCCACCGAAGAATTTATCCTGA
AAGCAGGGAAAGAACTTTTCGAATTTGTAGGAGCTAAACGTCTCAAAGGAATCAGCGGGGAAAGAAATATTTATTCTCCT
TTAAGTCAAGAACCTGACCCAAACCCTAGAAATGTAAAGTCATGA

Upstream 100 bases:

>100_bases
TGAAAGGTTAGACGTCTTTTAAAATAGTTCCTTATTTGTTTTTTAGTGTATTCTCAAAACCAATTCATATTGCTTATTTT
AAAGCCAAAACAAAAAGTTT

Downstream 100 bases:

>100_bases
TATATCTTTTTTATTCTTCCGTTTTTAATCGCAGGTTGCAATCCAAAGTTCCCGCCAAATGCTGAATTGCTCAAAGAATT
TCGGCTTGATACCTAATGCC

Product: adenylate/guanylate cyclase

Products: NA

Alternate protein names: ATP pyrophosphate-lyase 1; Adenylyl cyclase 1 [H]

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MRATLITIPNTNDMRASKVKMKDIIHWLSTHESRALEAKELIEILSRKMMEAGIPIWRFFTSIPTMHPEVMVRSIIWTRG
EETQIVFIPHDGLQQPQYKDSPIYLIREKQIDFIRCKLTGPEADLSYPICIDLHEKGGTDYCIFASVFGNNTRSAISWST
DTPGGFTDEQIDCLNSIRSILSLRLDLESRKFSINELLEVYLGPNASKRVLSGEFRRGTGETIYAAILCADLRDFSFLSE
NNPPKRIVEILDNYFELTAQPIQEEKGEILKFIGDAILAIFPAEVDSYKACLAALNAAQKIKNSVIRWNEEHPDLQIYLG
MALNVGDVVYGNVGAKDRLDFTVIGNAVNQAFRVESLCKDLGKNILATEEFILKAGKELFEFVGAKRLKGISGERNIYSP
LSQEPDPNPRNVKS

Sequences:

>Translated_414_residues
MRATLITIPNTNDMRASKVKMKDIIHWLSTHESRALEAKELIEILSRKMMEAGIPIWRFFTSIPTMHPEVMVRSIIWTRG
EETQIVFIPHDGLQQPQYKDSPIYLIREKQIDFIRCKLTGPEADLSYPICIDLHEKGGTDYCIFASVFGNNTRSAISWST
DTPGGFTDEQIDCLNSIRSILSLRLDLESRKFSINELLEVYLGPNASKRVLSGEFRRGTGETIYAAILCADLRDFSFLSE
NNPPKRIVEILDNYFELTAQPIQEEKGEILKFIGDAILAIFPAEVDSYKACLAALNAAQKIKNSVIRWNEEHPDLQIYLG
MALNVGDVVYGNVGAKDRLDFTVIGNAVNQAFRVESLCKDLGKNILATEEFILKAGKELFEFVGAKRLKGISGERNIYSP
LSQEPDPNPRNVKS
>Mature_414_residues
MRATLITIPNTNDMRASKVKMKDIIHWLSTHESRALEAKELIEILSRKMMEAGIPIWRFFTSIPTMHPEVMVRSIIWTRG
EETQIVFIPHDGLQQPQYKDSPIYLIREKQIDFIRCKLTGPEADLSYPICIDLHEKGGTDYCIFASVFGNNTRSAISWST
DTPGGFTDEQIDCLNSIRSILSLRLDLESRKFSINELLEVYLGPNASKRVLSGEFRRGTGETIYAAILCADLRDFSFLSE
NNPPKRIVEILDNYFELTAQPIQEEKGEILKFIGDAILAIFPAEVDSYKACLAALNAAQKIKNSVIRWNEEHPDLQIYLG
MALNVGDVVYGNVGAKDRLDFTVIGNAVNQAFRVESLCKDLGKNILATEEFILKAGKELFEFVGAKRLKGISGERNIYSP
LSQEPDPNPRNVKS

Specific function: Plays essential roles in regulation of cellular metabolism by catalyzing the synthesis of a second messenger, cAMP [H]

COG id: COG2114

COG function: function code T; Adenylate cyclase, family 3 (some proteins contain HAMP domain)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HAMP domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00211 Guanylate_cyc; PF00672 HAMP [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 46697; Mature: 46697

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: PS00037 MYB_1 ; PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRATLITIPNTNDMRASKVKMKDIIHWLSTHESRALEAKELIEILSRKMMEAGIPIWRFF
CCEEEEECCCCCCCHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHCCHHHHHH
TSIPTMHPEVMVRSIIWTRGEETQIVFIPHDGLQQPQYKDSPIYLIREKQIDFIRCKLTG
HHCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCEEEEEEECC
PEADLSYPICIDLHEKGGTDYCIFASVFGNNTRSAISWSTDTPGGFTDEQIDCLNSIRSI
CCCCCCCCEEEEEECCCCCCEEEEEEECCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHH
LSLRLDLESRKFSINELLEVYLGPNASKRVLSGEFRRGTGETIYAAILCADLRDFSFLSE
HHHHHCCCCCCCCHHHHHHHHCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
NNPPKRIVEILDNYFELTAQPIQEEKGEILKFIGDAILAIFPAEVDSYKACLAALNAAQK
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
IKNSVIRWNEEHPDLQIYLGMALNVGDVVYGNVGAKDRLDFTVIGNAVNQAFRVESLCKD
HHHHHHCCCCCCCCEEEEEEEEECCCCEEECCCCCCCCCEEEEECHHHHHHHHHHHHHHH
LGKNILATEEFILKAGKELFEFVGAKRLKGISGERNIYSPLSQEPDPNPRNVKS
HCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRATLITIPNTNDMRASKVKMKDIIHWLSTHESRALEAKELIEILSRKMMEAGIPIWRFF
CCEEEEECCCCCCCHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHCCHHHHHH
TSIPTMHPEVMVRSIIWTRGEETQIVFIPHDGLQQPQYKDSPIYLIREKQIDFIRCKLTG
HHCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCEEEEEEECC
PEADLSYPICIDLHEKGGTDYCIFASVFGNNTRSAISWSTDTPGGFTDEQIDCLNSIRSI
CCCCCCCCEEEEEECCCCCCEEEEEEECCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHH
LSLRLDLESRKFSINELLEVYLGPNASKRVLSGEFRRGTGETIYAAILCADLRDFSFLSE
HHHHHCCCCCCCCHHHHHHHHCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
NNPPKRIVEILDNYFELTAQPIQEEKGEILKFIGDAILAIFPAEVDSYKACLAALNAAQK
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
IKNSVIRWNEEHPDLQIYLGMALNVGDVVYGNVGAKDRLDFTVIGNAVNQAFRVESLCKD
HHHHHHCCCCCCCCEEEEEEEEECCCCEEECCCCCCCCCEEEEECHHHHHHHHHHHHHHH
LGKNILATEEFILKAGKELFEFVGAKRLKGISGERNIYSPLSQEPDPNPRNVKS
HCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11481430; 1970565 [H]