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The map label for this gene is manA

Identifier: 45658762

GI number: 45658762

Start: 3565357

End: 3566349

Strand: Reverse

Name: manA

Synonym: LIC12934

Alternate gene names: 45658762

Gene position: 3566349-3565357 (Counterclockwise)

Preceding gene: 45658763

Following gene: 45658761

Centisome position: 83.38

GC content: 37.66

Gene sequence:

>993_bases
ATGCAGAAAGTGATCCGCTTTCATCCGATCTATAAGGAAAGAATTTGGGGCGGTAGAAAATTAGGAGATTTTCCGGGAAG
AAAAATTCCAGAAGGAAACATAGGGGAATCCTGGGAAATCTCTGATTATGGAAATGATATTTCCATAATCAGGAACGGAC
CTTTGGCGGGCAAAAGTTTTCGAACCGCGTATTTGGAAAATACAGATACAATTTTGGGACGACCCTTTCGAGGAAAATCT
TTTCCTCTTCTAATTAAGATTATAGATGCAAAAGAAAAACTTTCCGTACAAGTACATCCCGATGACGTTTATGCAGAAAC
ATACGATCCGGAGAGCTCTGGAAAAAAAGAGGCCTGGATTGTTTTACAAGCAGAACCAGGATCTAAACTAATATGCGGTT
TTTTGAAAACTACAAACAGAGAAGAATTTAAAACCCTGGTGGAACAAAATAGAGCTGAAGAAATTTTAAGAGAGATTCCA
GTAAAAGAAGGTGACTCTTTTATTTTAAAACCCGGAAGAATTCACGCAATTGGTGCCGGAATTCTTTTGATGGAAGTACA
ACAATCTTCGGATTCTACTTATAGAGTTTACGATTATGGAAGGCTGAGAGAACTTCATCTTCAAAAGGCCCTAGACGTTT
TGGATTATGGCGGACCTTTCGAAGAAGATGTAATGAAACCAGTTCCAAAATCCTGGGATTTTGGAAATAGATTTCGTCTA
ACGGCAAATGATAAATTTTTGATGGAAACTTTGGAAATTTCTGGAAACGGAAAAACATTCCAAATTCCGAATGTTTATAA
AGAACCAGTCTTTCAGATTTTAACCGTTCTTCAGGGTAAAATTGAAATCGAGGGAGAATTACTTTTTCAAGGTGATACTT
TATTTTTAACCGCTGCCGGTCTGGAAGAAGGTATTTTTGCGGTTAATCGAAATGATCTGGCAAAGTTATCCGTGTCCGGA
CCTGGTTCCGATTGGATTATTTATAAAGATTAG

Upstream 100 bases:

>100_bases
TGGATCTTTCCGGATTAAAACTAGAAGGATTTGTCCATTTTAAAAAAAATCGTCTCAAAGTAAAAATTGAACTCCTGGAA
GGAGGGAAAAAATAGGTCTT

Downstream 100 bases:

>100_bases
AATTTTTAAATGGAACCAGAAGATTCTATAGTTTGGATCAGCGAAGAAGAACTCGCAAAACAAAGAAGAATTGCAAAAGA
TCTTCGCAAGACTTCTTGGT

Product: mannose-6-phosphate isomerase

Products: NA

Alternate protein names: Glucomannan utilization protein F; Phosphohexomutase; Phosphomannose isomerase; PMI [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MQKVIRFHPIYKERIWGGRKLGDFPGRKIPEGNIGESWEISDYGNDISIIRNGPLAGKSFRTAYLENTDTILGRPFRGKS
FPLLIKIIDAKEKLSVQVHPDDVYAETYDPESSGKKEAWIVLQAEPGSKLICGFLKTTNREEFKTLVEQNRAEEILREIP
VKEGDSFILKPGRIHAIGAGILLMEVQQSSDSTYRVYDYGRLRELHLQKALDVLDYGGPFEEDVMKPVPKSWDFGNRFRL
TANDKFLMETLEISGNGKTFQIPNVYKEPVFQILTVLQGKIEIEGELLFQGDTLFLTAAGLEEGIFAVNRNDLAKLSVSG
PGSDWIIYKD

Sequences:

>Translated_330_residues
MQKVIRFHPIYKERIWGGRKLGDFPGRKIPEGNIGESWEISDYGNDISIIRNGPLAGKSFRTAYLENTDTILGRPFRGKS
FPLLIKIIDAKEKLSVQVHPDDVYAETYDPESSGKKEAWIVLQAEPGSKLICGFLKTTNREEFKTLVEQNRAEEILREIP
VKEGDSFILKPGRIHAIGAGILLMEVQQSSDSTYRVYDYGRLRELHLQKALDVLDYGGPFEEDVMKPVPKSWDFGNRFRL
TANDKFLMETLEISGNGKTFQIPNVYKEPVFQILTVLQGKIEIEGELLFQGDTLFLTAAGLEEGIFAVNRNDLAKLSVSG
PGSDWIIYKD
>Mature_330_residues
MQKVIRFHPIYKERIWGGRKLGDFPGRKIPEGNIGESWEISDYGNDISIIRNGPLAGKSFRTAYLENTDTILGRPFRGKS
FPLLIKIIDAKEKLSVQVHPDDVYAETYDPESSGKKEAWIVLQAEPGSKLICGFLKTTNREEFKTLVEQNRAEEILREIP
VKEGDSFILKPGRIHAIGAGILLMEVQQSSDSTYRVYDYGRLRELHLQKALDVLDYGGPFEEDVMKPVPKSWDFGNRFRL
TANDKFLMETLEISGNGKTFQIPNVYKEPVFQILTVLQGKIEIEGELLFQGDTLFLTAAGLEEGIFAVNRNDLAKLSVSG
PGSDWIIYKD

Specific function: Seems to be involved in the degradation of glucomannan [H]

COG id: COG1482

COG function: function code G; Phosphomannose isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR001250
- InterPro:   IPR014628
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01238 PMI_typeI [H]

EC number: =5.3.1.8 [H]

Molecular weight: Translated: 37320; Mature: 37320

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKVIRFHPIYKERIWGGRKLGDFPGRKIPEGNIGESWEISDYGNDISIIRNGPLAGKSF
CCCCEEECCCHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCEEEEEECCCCCCCCE
RTAYLENTDTILGRPFRGKSFPLLIKIIDAKEKLSVQVHPDDVYAETYDPESSGKKEAWI
EEEEECCCCHHCCCCCCCCCCEEEEEEECCCCEEEEEECCCCEEEECCCCCCCCCCEEEE
VLQAEPGSKLICGFLKTTNREEFKTLVEQNRAEEILREIPVKEGDSFILKPGRIHAIGAG
EEEECCCCCEEEEEHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEEECC
ILLMEVQQSSDSTYRVYDYGRLRELHLQKALDVLDYGGPFEEDVMKPVPKSWDFGNRFRL
EEEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCEEEE
TANDKFLMETLEISGNGKTFQIPNVYKEPVFQILTVLQGKIEIEGELLFQGDTLFLTAAG
ECCCEEEEEEEEECCCCCEEECCCHHHHHHHHHHHHHCCEEEEEEEEEEECCEEEEEECC
LEEGIFAVNRNDLAKLSVSGPGSDWIIYKD
CCCCEEEECCCCEEEEEECCCCCCEEEEEC
>Mature Secondary Structure
MQKVIRFHPIYKERIWGGRKLGDFPGRKIPEGNIGESWEISDYGNDISIIRNGPLAGKSF
CCCCEEECCCHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCEEEEEECCCCCCCCE
RTAYLENTDTILGRPFRGKSFPLLIKIIDAKEKLSVQVHPDDVYAETYDPESSGKKEAWI
EEEEECCCCHHCCCCCCCCCCEEEEEEECCCCEEEEEECCCCEEEECCCCCCCCCCEEEE
VLQAEPGSKLICGFLKTTNREEFKTLVEQNRAEEILREIPVKEGDSFILKPGRIHAIGAG
EEEECCCCCEEEEEHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEEECC
ILLMEVQQSSDSTYRVYDYGRLRELHLQKALDVLDYGGPFEEDVMKPVPKSWDFGNRFRL
EEEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCEEEE
TANDKFLMETLEISGNGKTFQIPNVYKEPVFQILTVLQGKIEIEGELLFQGDTLFLTAAG
ECCCEEEEEEEEECCCCCEEECCCHHHHHHHHHHHHHCCEEEEEEEEEEECCEEEEEECC
LEEGIFAVNRNDLAKLSVSGPGSDWIIYKD
CCCCEEEECCCCEEEEEECCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9202461; 9384377 [H]