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The map label for this gene is pdxA

Identifier: 45658650

GI number: 45658650

Start: 3423358

End: 3424416

Strand: Reverse

Name: pdxA

Synonym: LIC12820

Alternate gene names: 45658650

Gene position: 3424416-3423358 (Counterclockwise)

Preceding gene: 45658651

Following gene: 45658649

Centisome position: 80.06

GC content: 39.75

Gene sequence:

>1059_bases
GTGAACCGGATTCTGATTACAGAAGGAGATCCTTGTGGGATCGGTCCGGAGATTTTTCTCGATACACTTTCCCTTTTAAA
AAAAATCTCTAAAACAAGACCAATCGTCTATTTTCATTCCGGTAAATATTCGCTTCCAAAAGAATTTGTTTCGATGCCGA
TGGACGTCGCCGATGTTTCGTCGATCAATGCGGTTTTCAATTCTAAAATTTCAGAGCGTCTTATAGCAGAAGCCTCGTCC
CAAATTTTGAAAAAAGGTTTGTTCTCGATTTCGCATAACGTACTTTCTAAAAAGGAAATTTCTGCTTTGAAATTTGGCAA
ACCGTCCGCTTTGTCTGGAAAATCTGCGTTGGCTACTCTTTCTCTTGCAGTGAGATTTCAAAAAGAAGGAGGTGGTGATT
TAATCACTCTTCCGTTGAGTAAAGAATGGGTAATTGCTTCTGGGGCTTCTACGTTTCGAGGTCATACTGAATTTCTCGCG
GAAGAATATCGTACTCAGACATTTATGCTGATGTCCGGCAAAGATCTTCAGGTTCTTCCTTTAACGACTCATGTTCCACT
CGTAAAAGTTCCGGAGTTTTTGAAAGAGGTAGATTTAGATTCTCTTGCTGATTCTATTTTTTCTTGTCAGAAAATCGATC
TCAAAAAACCGATCGTGTTTCTTGGTCTTAACCCACACGCGGGGGAAGGTGGTAAAATAGGAAAGGAAGAAGTCGAGATT
CTCGAACCTATAATTCAATTCTTAAAGAAAAAAGGTTTAAAAGTAGAAGGGCCCCTTTCCGCTGATTCAATGTTTGGTGA
ATCTTCTCGAAAAAAATTTGGTCTTCATATAGCCTGTTATCACGATCAGGGGCTGATTCCTTTTAAAATGTGGGAGGGAA
AAAGGGGTGTAAATCTAACTTTGGGCCTTCCATTTATAAGGGTTTCTCCGGATCATGGAACTGCATTTGACATTGCTGGG
AAAGGACTTGCAGATTCGACTAGTTTTGTAGAATGCCTGAACCAAGTTGTGAAAGATCTTCAAGCAAAACGTTCTAACAA
AGAAAAGTTTCGTTTGTAG

Upstream 100 bases:

>100_bases
CGTTGAAAAAATCTTCGGAAAACAATCCGGGGCTAGAGAATAATTCGCAAGGTTTTCTTTCCGGAAAAAAATTTTCGGAA
TCAAAACAGACTTCAAAGAA

Downstream 100 bases:

>100_bases
GTAAGTTAGAAGTGTCGATGTTAAAAAATAGAAACGAGGTTTTATGCCTGGACTTTTAGAACAAATCGTATTTCCAATTT
TCCTTTTTTGGTTTTGCGGA

Product: pyridoxal phosphate biosynthesis protein

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MNRILITEGDPCGIGPEIFLDTLSLLKKISKTRPIVYFHSGKYSLPKEFVSMPMDVADVSSINAVFNSKISERLIAEASS
QILKKGLFSISHNVLSKKEISALKFGKPSALSGKSALATLSLAVRFQKEGGGDLITLPLSKEWVIASGASTFRGHTEFLA
EEYRTQTFMLMSGKDLQVLPLTTHVPLVKVPEFLKEVDLDSLADSIFSCQKIDLKKPIVFLGLNPHAGEGGKIGKEEVEI
LEPIIQFLKKKGLKVEGPLSADSMFGESSRKKFGLHIACYHDQGLIPFKMWEGKRGVNLTLGLPFIRVSPDHGTAFDIAG
KGLADSTSFVECLNQVVKDLQAKRSNKEKFRL

Sequences:

>Translated_352_residues
MNRILITEGDPCGIGPEIFLDTLSLLKKISKTRPIVYFHSGKYSLPKEFVSMPMDVADVSSINAVFNSKISERLIAEASS
QILKKGLFSISHNVLSKKEISALKFGKPSALSGKSALATLSLAVRFQKEGGGDLITLPLSKEWVIASGASTFRGHTEFLA
EEYRTQTFMLMSGKDLQVLPLTTHVPLVKVPEFLKEVDLDSLADSIFSCQKIDLKKPIVFLGLNPHAGEGGKIGKEEVEI
LEPIIQFLKKKGLKVEGPLSADSMFGESSRKKFGLHIACYHDQGLIPFKMWEGKRGVNLTLGLPFIRVSPDHGTAFDIAG
KGLADSTSFVECLNQVVKDLQAKRSNKEKFRL
>Mature_352_residues
MNRILITEGDPCGIGPEIFLDTLSLLKKISKTRPIVYFHSGKYSLPKEFVSMPMDVADVSSINAVFNSKISERLIAEASS
QILKKGLFSISHNVLSKKEISALKFGKPSALSGKSALATLSLAVRFQKEGGGDLITLPLSKEWVIASGASTFRGHTEFLA
EEYRTQTFMLMSGKDLQVLPLTTHVPLVKVPEFLKEVDLDSLADSIFSCQKIDLKKPIVFLGLNPHAGEGGKIGKEEVEI
LEPIIQFLKKKGLKVEGPLSADSMFGESSRKKFGLHIACYHDQGLIPFKMWEGKRGVNLTLGLPFIRVSPDHGTAFDIAG
KGLADSTSFVECLNQVVKDLQAKRSNKEKFRL

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=346, Percent_Identity=33.2369942196532, Blast_Score=153, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 38652; Mature: 38652

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRILITEGDPCGIGPEIFLDTLSLLKKISKTRPIVYFHSGKYSLPKEFVSMPMDVADVS
CCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHCCCCHHHHH
SINAVFNSKISERLIAEASSQILKKGLFSISHNVLSKKEISALKFGKPSALSGKSALATL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHEE
SLAVRFQKEGGGDLITLPLSKEWVIASGASTFRGHTEFLAEEYRTQTFMLMSGKDLQVLP
EEEEEEECCCCCCEEEECCCCCEEEECCCHHHCHHHHHHHHHHCCEEEEEECCCCEEEEE
LTTHVPLVKVPEFLKEVDLDSLADSIFSCQKIDLKKPIVFLGLNPHAGEGGKIGKEEVEI
ECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCHHHHHH
LEPIIQFLKKKGLKVEGPLSADSMFGESSRKKFGLHIACYHDQGLIPFKMWEGKRGVNLT
HHHHHHHHHHCCCEEECCCCHHHHCCCCCCCEECEEEEEEECCCCEEEEECCCCCCCEEE
LGLPFIRVSPDHGTAFDIAGKGLADSTSFVECLNQVVKDLQAKRSNKEKFRL
ECCCEEEECCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHCCC
>Mature Secondary Structure
MNRILITEGDPCGIGPEIFLDTLSLLKKISKTRPIVYFHSGKYSLPKEFVSMPMDVADVS
CCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHCCCCHHHHH
SINAVFNSKISERLIAEASSQILKKGLFSISHNVLSKKEISALKFGKPSALSGKSALATL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHEE
SLAVRFQKEGGGDLITLPLSKEWVIASGASTFRGHTEFLAEEYRTQTFMLMSGKDLQVLP
EEEEEEECCCCCCEEEECCCCCEEEECCCHHHCHHHHHHHHHHCCEEEEEECCCCEEEEE
LTTHVPLVKVPEFLKEVDLDSLADSIFSCQKIDLKKPIVFLGLNPHAGEGGKIGKEEVEI
ECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCHHHHHH
LEPIIQFLKKKGLKVEGPLSADSMFGESSRKKFGLHIACYHDQGLIPFKMWEGKRGVNLT
HHHHHHHHHHCCCEEECCCCHHHHCCCCCCCEECEEEEEEECCCCEEEEECCCCCCCEEE
LGLPFIRVSPDHGTAFDIAGKGLADSTSFVECLNQVVKDLQAKRSNKEKFRL
ECCCEEEECCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA